Clinical Trials on Lower Respiratory Tract Infections

Total 65975 results

Chinese University of Hong Kong

Recruiting

Incidence of HANA Conditions in HIV-infected Individuals

Metabolic Syndrome | Vitamin D Deficiency | Renal Impairment | HIV | Osteoporosis | Osteopenia | Liver Fibroses

Hong Kong
Genelux Corporation

Completed

GL-ONC1 Oncolytic Immunotherapy in Patients With Recurrent or Refractory Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Carcinomatosis

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Triple-Negative Breast Carcinoma and other conditions

United States, Canada
Istituti Clinici Scientifici Maugeri SpA
University of Pavia; Academisch Medisch Centrum - Universiteit van Amsterdam... and other collaborators

Completed

Pilot Study of the eHealth Application "Cancer Patients Better Life Experience" (CAPABLE) - Italy (CAPABLE-IT)

Stomach Cancer | Breast Cancer | Head and Neck Cancer | Lung Cancer | Thyroid Cancer | Renal Cell Carcinoma Metastatic | Ovary Cancer

Italy
Cancer Research UK

Active, not recruiting

A CR-UK Phase I Trial of LY3143921

a. Colorectal Cancer | b. High Grade Serous Ovarian Cancer | c. Non Small-cell Lung Cancer (Squamous Cell Variant) | d. Squamous Carcinoma of the Oesophagus | e. Squamous Carcinoma of the Head and Neck (HPV Negative) | f. Urothelial Cancer | g. Breast Cancer (Triple Negative Type) | h. Pancreatic...

United Kingdom
Genmab
AbbVie

Terminated

A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors

Esophageal Cancer | Prostate Cancer | Bladder Cancer | Non-small Cell Lung Cancer (NSCLC) | Uterine Cancer | Triple Negative Breast Cancer (TNBC) | Squamous Cell Carcinoma of Head and Neck (SCCHN) | Locally Advanced or Metastatic Solid Tumor(s)

Spain, Israel, United States, Denmark
Roswell Park Cancer Institute

Completed

Body Warming in Improving Blood Flow and Oxygen Delivery to Tumors in Patients With Cancer

Melanoma | Soft Tissue Sarcoma | Breast Carcinoma | Lung Carcinoma | Malignant Neoplasm | Colon Carcinoma | Ovarian Neoplasm | Malignant Head and Neck Neoplasm | Adult Liver Carcinoma | Kidney Neoplasm

United States
MacroGenics

Terminated

Safety Study of MGD009 in B7-H3-expressing Tumors

Melanoma | Soft Tissue Sarcoma | Clear Cell Renal Cell Carcinoma | Breast Cancer | Pancreatic Cancer | Ovarian Cancer | Prostate Cancer | Non Small Cell Lung Cancer | Mesothelioma | Squamous Cell Carcinoma of the Head and Neck | Bladder Cancer | Colon Cancer | Thyroid Cancer

United States, Australia, Canada
HiFiBiO Therapeutics

Recruiting

A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors

Melanoma | Sarcoma | Renal Cell Carcinoma | Cervical Cancer | Testicular Germ Cell Tumor | Gastric Cancer | Non Small Cell Lung Cancer | Mesothelioma | Head and Neck Squamous Cell Carcinoma

United States, Spain
Fusion Pharmaceuticals Inc.

Terminated

A Study of [225Ac]-FPI-1966 in Participants With Advanced Solid Tumours

Breast Cancer | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Liver Cancer | Bladder Carcinoma | Susceptible FGFR3 Genetic Alterations | FGFR3 | FGFR3 Overexpression | FGFR3 Receptor | FGFR3 Protein Overexpression

United States, Australia
Pfizer

Terminated

Study to Test the Safety and Tolerability of PF-07209960 in Advanced or Metastatic Solid Tumors

Renal Cell Carcinoma | Non-small-cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Urothelial Carcinoma | Colorectal Carcinoma | Ovarian Carcinoma

United States
Michael Har-Noy
Hadassah Medical Organization

Completed

Experimental Therapeutic Cancer Vaccine Created In-situ in Patients With Stage II-Stage IV Cancer

Melanoma | Sarcoma | Breast Cancer | Colorectal Cancer | Ovarian Cancer | Prostate Cancer | Non-small Cell Lung Cancer | Solid Tumors Stage II, Stage III and Stage IV

Israel
Xencor, Inc.
ICON plc

Completed

A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors (DUET-2)

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Nasopharyngeal Carcinoma | Small Cell Lung Carcinoma | Hepatocellular Carcinoma | Thymic Carcinoma | Thymoma | Non-small Cell Lung Carcinoma | Mesothelioma | Squamous Cell Carcinoma of the Head and Neck | Cholangiocarcinoma | Breast Carcinoma | Fallopian Tube Carcinoma and other conditions

United States
Mayo Clinic

Recruiting

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Malignant Solid Neoplasm | Renal Cell Carcinoma | Hepatocellular Carcinoma | Metastatic Cutaneous Melanoma | Unresectable Cutaneous Melanoma | Lung Non-Small Cell Carcinoma | Urothelial Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Recurrent Head and Neck Squamous... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

National Cancer Institute "Cancer Moonshot Biobank"

Malignant Solid Neoplasm | Acute Myeloid Leukemia | Multiple Myeloma | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer... and other conditions

United States, Puerto Rico
LG Chem

Not yet recruiting

Study to Evaluate LB-LR1109 for the Treatment of Solid Tumors (LB-LR1109)

Urothelial Carcinoma | Malignant Melanoma | Non-small Cell Lung Cancer(NSCLC) | Head and Neck Squamous Cell Carcinoma(HNSCC) | Renal Cell Carcinoma(RCC)
Sensei Biotherapeutics, Inc.
Regeneron Pharmaceuticals

Recruiting

A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Melanoma | Sarcoma | Kidney Cancer | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Bladder Cancer | Cervix Cancer | Advanced Solid Tumor | Advanced Cancer | Colon Cancer | Thyroid Cancer | Solid Tumor... and other conditions

United States
Mohamed Abdel-Rahman

Recruiting

Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

Renal Cell Carcinoma | Hepatocellular Carcinoma | Mesothelioma | Cholangiocarcinoma | Uveal Melanoma | Cutaneous Melanoma | Meningioma Atypical | BAP1 Gene Mutation

United States
Kymab Limited
Sanofi

Active, not recruiting

Safety and Efficacy of KY1044 and Atezolizumab in Advanced Cancer

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Metastatic Cancer | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Advanced Cancer

United States, Hungary, Italy, Poland, Taiwan, United Kingdom
Comprehensive Support Project for Oncology Research

Active, not recruiting

Patient Reported Outcomes Study Using Electronic Monitoring System for Advanced or Metastatic Solid Cancer

Stomach Cancer | Breast Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Endometrial Cancer | Liver Cancer

Japan
NGM Biopharmaceuticals, Inc
Merck Sharp & Dohme LLC

Active, not recruiting

Study of NGM438 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumors

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Breast Cancer | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Non Small Cell Lung Cancer | Mesothelioma | Squamous Cell Carcinoma of Head and Neck | Cholangiocarcinoma | Bladder Urothelial Cancer | Endocervical...

United States
Numab Therapeutics AG

Terminated

A Study of NM21-1480 in Adult Patients With Advanced Solid Tumors

Colorectal Cancer | Fallopian Tube Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Non-small Cell Lung Cancer | Peritoneal Carcinoma | Head and Neck Squamous Cell Carcinoma | Ovarian Carcinoma | Squamous Cell Carcinoma

United States, Taiwan, Spain
Kite, A Gilead Company

Terminated

A Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers

Multiple Myeloma | Ovarian Cancer | Fallopian Tube Cancer | Non-Small Cell Lung Cancer | Triple Negative Breast Cancer | Pancreatic Ductal Adenocarcinoma

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center

Not yet recruiting

Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

HIV Infection | Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Recurrent... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IVA Lip and Oral... and other conditions

United States, Canada
Abramson Cancer Center of the University of Pennsylvania

Completed

Capecitabine and Lapatinib Ditosylate in Treating Patients With Squamous Cell Cancer of the Head and Neck

Head and Neck Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck Cancer

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IV Hypopharyngeal Carcinoma AJCC v8 | Stage IV Laryngeal Cancer... and other conditions

United States
University of South Florida
Boston University; University of Pennsylvania; Data Management and Coordinating...

Completed

Educational Needs of Patients With Systemic Vasculitis

Giant Cell Arteritis | Vasculitis, Central Nervous System | Microscopic Polyangiitis | Churg-Strauss Syndrome | Polyarteritis Nodosa | Takayasu's Arteritis | Behcet's Disease | Henoch-Schoenlein Purpura | Wegener Granulomatosis

United States
Marcelo Bonomi

Recruiting

Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

Prognostic Stage IIIC Breast Cancer AJCC v8 | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Melanoma | Stage IV Lung Cancer AJCC v8 | Locally Advanced Malignant Solid Neoplasm | Locally... and other conditions

United States
M.D. Anderson Cancer Center
Millennium Pharmaceuticals, Inc.

Withdrawn

Alisertib and TAK-228 in Participants With Human Papilloma Virus (HPV) Associated Malignancies

Malignant Neoplasms of Female Genital Organs | Malignant Neoplasms of Lip Oral Cavity and Pharynx | Malignant Neoplasms of Digestive Organs | Malignant Neoplasms of Male Genital Organs
GeneMedicine Co., Ltd.

Recruiting

GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors

Renal Cell Carcinoma | Cervical Cancer | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Malignant Melanoma

Korea, Republic of
Adrenas Therapeutics Inc

Recruiting

A Study to Determine Eligibility for CAH-301 (A Study of Gene Therapy for Classic Congenital Adrenal Hyperplasia (CAH) [NCT04783181])

Congenital Adrenal Hyperplasia

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center; Janssen... and other collaborators

Recruiting

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

Plasmablastic Lymphoma | Ann Arbor Stage I Diffuse Large B-Cell Lymphoma | Ann Arbor Stage II Diffuse Large B-Cell Lymphoma | Ann Arbor Stage III Diffuse Large B-Cell Lymphoma | Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Small Intestine Cancer | Brain and Central Nervous System Tumors | Lymphoproliferative Disorder

United States, Canada
University Hospital, Bordeaux

Recruiting

Functional Tests to Resolve Unsolved Rare Diseases. Rares. (RID)

Intellectual Disability | Cystic Fibrosis | Neurodegeneration With Brain Iron Accumulation (NBIA) | Congenital Heart Defect | Albinism | Rubinstein-Taybi Syndrome | Periventricular Nodular Heterotopia

France
Masonic Cancer Center, University of Minnesota

Recruiting

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies

Common Variable Immunodeficiency | Chronic Granulomatous Disease | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | X-linked Lymphoproliferative Disease | Langerhan's Cell Histiocytosis | Chediak-Higashi Syndrome | Griscelli Syndrome | Bare Lymphocyte Syndrome | SCID | Omenn's Syndrome | Reticular... and other conditions

United States
University of South Florida
Boston University; Yale University

Completed

Vasculitis Illness Perception (VIP) Study

Giant Cell Arteritis | Microscopic Polyangiitis | Churg-Strauss Syndrome | Polyarteritis Nodosa | Takayasu's Arteritis | Behcet's Disease | CNS Vasculitis | Henoch-Schoenlein Purpura | Wegener Granulomatosis

United States
University of South Florida
Boston University; Duke University; Data Management and Coordinating Center (DMCC)

Completed

Reproductive Health in Men and Women With Vasculitis

Giant Cell Arteritis | Vasculitis, Central Nervous System | Wegener's Granulomatosis | Microscopic Polyangiitis | Churg-Strauss Syndrome | Polyarteritis Nodosa | Takayasu's Arteritis | Kawasaki Disease | Behcet's Disease | Henoch-schoenlein Purpura | Drug-induced Necrotizing Vasculitis

United States
Loxo Oncology, Inc.
Eli Lilly and Company

Recruiting

A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumors (LIBRETTO-121)

Soft Tissue Sarcoma | Medullary Thyroid Cancer | Papillary Thyroid Cancer | Infantile Fibrosarcoma | Infantile Myofibromatosis

United States, Australia, Japan, Canada, Germany, Korea, Republic of, France, Spain, United Kingdom, Denmark, Italy
Steno Diabetes Center Copenhagen
King's College London; Juvenile Diabetes Research Foundation; Glostrup University...

Not yet recruiting

Prevention of Chronic Kidney Disease(CDK) Progression in Type 1 Diabetes With Long Term Use of Sodium-Glucose-coTransporter Inhibitors Avoiding Kidney hypOxia (PLUTO)

Hypoxia | Diabetes Mellitus, Type 1 | Diabetic Nephropathies | Albuminuria | Nephropathy | Diabetic Complications Renal | Diabetic Complications Cardiovascular

Denmark
Kyunghee Burkitt, DO, PhD

Not yet recruiting

Vorinostat in Combination With Chemoradiation in Locally Advanced HPV Negative HNSCC (HPV)

Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Oral Cavity | HPV-Related Squamous Cell Carcinoma | Squamous Cell Carcinoma of the Oropharynx | Squamous Cell Carcinoma of the Hypopharynx

United States
University of Arkansas

Withdrawn

PK and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia

Acute Kidney Injury | Hypoxic-Ischemic Encephalopathy | Caffeine

United States
Wroclaw Medical University

Enrolling by invitation

Selected Disorders and Sleep Bruxism

Cardiovascular Diseases | Hypertension | Sleep Apnea | Cardiovascular Risk Factor | Sleep Disorders | Temporomandibular Disorder | Sleep Bruxism | Thyroid Dysfunction | Mental Status Change

Poland
Beijing Anzhen Hospital

Completed

Tissue Oxygenation During Treatment of Infant Congenital Heart Defects

Acute Kidney Injury | Hypoxia-Ischemia, Brain | Mesenteric Ischemia

China
Maastricht Radiation Oncology

Terminated

Tumor Hypoxia With HX4 PET in Several Diseases (HX4 SD)

Prostatic Neoplasms | Esophageal Neoplasms | Rectal Neoplasms | Brain Neoplasm, Primary | Neoplasm Metastases, Brain

Netherlands
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Thalidomide in Treating Patients With Metastatic Neuroendocrine Tumors

Lung Cancer | Islet Cell Tumor | Gastrointestinal Carcinoid Tumor | Neoplastic Syndrome

United States
N.N. Petrov National Medical Research Center of...

Recruiting

Leflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS Mutations (NТО-RAS)

Melanoma | Lung Cancer | Pancreas Cancer | Refractory Cancer | Colorectal Cancer Recurrent | RAS Mutation | Ras (Kras or Nras) Gene Mutation

Russian Federation
Erasmus Medical Center

Not yet recruiting

Fluorescence-guided Surgery in Laryngeal- and Hypopharyngeal Cancer: a Feasibility Trial (STELLAR)

Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Hypopharynx

Netherlands
Seagen Inc.

Recruiting

A Study of SGN-BB228 in Advanced Melanoma and Other Solid Tumors

Colorectal Neoplasms | Pancreatic Neoplasms | Mesothelioma | Non-small Cell Lung Cancer | Cutaneous Melanoma

United States, Canada, Switzerland, France, Germany, United Kingdom

Clinical Trials on Lower Respiratory Tract Infections

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