Clinical Trials on Lung Injury in United Kingdom

Total 23589 results

Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Study in Adult and Adolescent Subjects With PAR (Perennial Allergic Rhinitis)

Rhinitis, Allergic, Perennial

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Inhaled Sargramostim in Treating Patients With Melanoma Metastatic to the Lung

Metastatic Cancer | Melanoma (Skin)

United States
Novartis Pharmaceuticals

Terminated

Study of Efficacy and Safety of Ligelizumab in Adolescents and Adults With Chronic Inducible Urticaria Who Remain Symptomatic Despite Treatment With H1- Antihistamines (PEARL-PROVOKE)

Chronic Inducible Urticaria

Taiwan, Turkey, United States, Australia, Hungary, Spain, Greece, Russian Federation, Slovakia
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Collection of Patient-Reported Symptoms and Performance Status Via the Internet

Leukemia | Breast Cancer | Multiple Myeloma | Colorectal Cancer | Lung Cancer | Prostate Cancer

United States
Advancis Pharmaceutical Corporation

Completed

APC-111 MP Tablet Once a Day vs.Penicillin VK Four Times a Day Both for 10 Days in Patients With Strep Throat

Tonsillitis | Pharyngitis | Sore Throat

United States, Canada
National Institute of Allergy and Infectious Diseases...
Juvenile Diabetes Research Foundation; Immune Tolerance Network (ITN)

Terminated

A Research Trial of Aralast in New Onset Diabetes (RETAIN) (RETAIN)

Diabetes Mellitus, Type 1

United States
Edwards Lifesciences

Active, not recruiting

ALTERRA: SAPIEN 3 THV With the Alterra Adaptive Prestent

Tetralogy of Fallot | Pulmonary Disease | Congenital Heart Disease | Pulmonary Regurgitation | Transcatheter Pulmonary Valve Replacement (TPVR)

United States
GlaxoSmithKline

Completed

Persistence Study of GSK Biologicals' Tdap Vaccine 1, 3, 5 and 9 Years Following Administration as an Initial Single Dose in Healthy Young Adults and to Evaluate the Immunogenicity and Safety of Boostrix as a Second Dose of Tdap, When Administered at Year 9

Tetanus | Diphtheria | Acellular Pertussis

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Paclitaxel, Cisplatin, and Filgrastim Combined With Radiation Therapy in Treating Patients With Locally Recurrent Head and Neck Cancer

Head and Neck Cancer

United States, Canada
Janssen Research & Development, LLC
Janssen Pharmaceuticals

Completed

Study of Acute Uncomplicated Seasonal Influenza A in Adult Subjects

Influenza A

United States, Germany, Bulgaria, Canada, Estonia, Latvia, Belgium, Puerto Rico
Washington University School of Medicine
University of Rochester; ResMed Foundation; The Hebrew University Hadassah Medical...

Terminated

Sleep Apnea and Fetal Growth Restriction (SAFER)

Obstructive Sleep Apnea | Pregnancy Related | Fetal Growth Restriction

United States, Israel
I-Mab Biopharma US Limited

Completed

A Clinical Study of TJ004309 With Atezolizumab (TECENTRIQ®) in Patients With Ovarian Cancer and Selected Solid Tumors

Head and Neck Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Gastrointestinal Cancer | Ovarian Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Chemotherapy and/or Metastasectomy in Treating Patients With Metastatic Colorectal Adenocarcinoma With Lung Metastases

Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Colorectal Carcinoma Metastatic in the Lung

United States, Canada
GlaxoSmithKline

Completed

Fluticasone Furoate Nasal Spray Versus Oral Fexofenadine

Rhinitis, Allergic, Seasonal

United States
Gilead Sciences

Completed

Pharmacokinetics of Eleclazine in Adults With Normal and Impaired Hepatic Function

Long QT Syndrome

United States, Romania, New Zealand, Germany
University of Colorado, Denver
National Cancer Institute (NCI)

Completed

Multimedia Educational Program for Patients With Early-Stage Prostate Cancer or Breast Cancer

Depression | Breast Cancer | Prostate Cancer | Psychosocial Effects of Cancer and Its Treatment | Long-term Effects of Cancer Treatment

United States
Lyra Therapeutics

Active, not recruiting

Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (ENLIGHTEN 1)

Chronic Sinusitis | Chronic Rhinosinusitis (Diagnosis)

United States, Austria, Czechia, Poland, Spain
Eli Lilly and Company

Not yet recruiting

A Study of Lebrikizumab in Adult Participants With Perennial Allergic Rhinitis (PREPARED-1)

Perennial Allergic Rhinitis (PAR)

United States
University of Utah
National Cancer Institute (NCI)

Terminated

CPAP in Treating Obstructive Sleep Apnea in Patients With Polycythemia Vera or Essential Thrombocythemia

Obstructive Sleep Apnea Syndrome | Polycythemia Vera | Essential Thrombocythemia | CALR Gene Mutation | JAK2 Gene Mutation | MPL Gene Mutation

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR); Medical Research Council of...

Completed

Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP) (TIPP)

Ductus Arteriosus, Patent | Infant, Very Low Birth Weight | Infant, Premature

United States
University of Maryland, Baltimore

Recruiting

Comparing Direct vs Indirect Methods for Cascade Screening

Familial Hypercholesterolemia | Long QT Syndrome | Genetic Testing | Ethics

United States
BioCryst Pharmaceuticals

Completed

A Phase II, Multicenter, Randomized, Placebo -Controlled, Study To Evaluate The Efficacy and Safety Of Intramuscular Peramivir 600 mg In Subjects With Uncomplicated Acute Influenza

Acute, Uncomplicated Human Influenza

United States, Australia, New Zealand, South Africa
VA Office of Research and Development
US Department of Veterans Affairs

Completed

Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program

Heart Failure | Pneumonia | Cellulitis | Urinary Retention | Deep Venous Thrombosis | Hydronephrosis | Pleural Effusion | Abdominal Aortic Aneurysm | Acute Cholecystitis | Other Acute Illnesses Presenting to the Hospital | Peritoneal Free Fluid

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Cutaneous Melanoma | Recurrent Malignant Female Reproductive System Neoplasm | Refractory Malignant Female Reproductive System Neoplasm | Recurrent Lip and Oral Cavity Carcinoma | Recurrent Malignant Endocrine... and other conditions

United States
Novo Nordisk A/S

Terminated

Effect of Inhaled Pre-prandial Human Insulin on Blood Glucose Control in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

United States
Haiyan Li
Peking University; Food and Drug Administration (FDA); Spaulding Clinical Research... and other collaborators

Unknown

Race Difference Moxifloxacin-induced QT Prolongation Between Healthy Chinese and Caucasian Volunteers

Cardiac Toxicity

United States, China
Mannkind Corporation

Completed

Comparison of Technosphere® Insulin Versus Technosphere Powder (Placebo) in Insulin-Naive Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes

United States, Russian Federation, Brazil, Ukraine
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Flu Vaccine in Preventing Influenza Infection in Healthy Volunteers and in Patients Who Have Undergone Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Nonmalignant Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Safety and Effectiveness of Zidovudine in the Treatment of HIV-Infected Children With Mild to Moderate Symptoms

HIV Infections

United States
AstraZeneca

Completed

Investigation of the Efficacy and Safety of Concomitant Administration of Ciclesonide Nasal Spray and Azelastine Nasal Spray in Patients (18 Years or Older) With Perennial Allergic Rhinitis (PAR) Not Adequately Controlled on an Intranasal Corticosteroid or Antihistamine Monotherapy (BY9010/M1-490)

Rhinitis, Allergic, Perennial

United States
GlaxoSmithKline

Completed

Once-Daily Investigational Nasal Spray In Adults And Adolescents With Perennial Allergic Rhinitis (PAR)

Rhinitis, Allergic, Perennial

Australia, Estonia, United States, Germany, Canada, New Zealand, Russian Federation, Lithuania, Latvia
GlaxoSmithKline

Completed

A Clinical Study To Test A Nasal Spray (Fluticasone Furoate Nasal Spray) For The Treatment Of Perennial (Year-round) Allergic Rhinitis

Rhinitis, Allergic, Perennial

Estonia, United States, Canada, Germany, Slovakia, Russian Federation, Hungary
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Evaluate the Effects of Azithromycin on MAC Disease Prevention in HIV-Positive Patients

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
University of Chicago

Suspended

Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy

Gastric Cancers

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Recruiting

A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

Cervical Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Bladder Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Renal Pelvis Cancer | Urinary Bladder Neoplasm | Recurrent...

United States
University of Michigan
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Recruiting

Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia

Obstructive Sleep Apnea | Down Syndrome | Tolerance | Trisomy 21 | Hypertonia, Muscle | Nasal Airway Obstruction

United States
Exelixis

Active, not recruiting

Study of Cabozantinib in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors

Renal Cell Carcinoma | Head and Neck Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Triple Negative Breast Cancer | Endometrial Cancer | Castration-resistant Prostate Cancer | Urothelial Carcinoma | Differentiated Thyroid Cancer | Gastroesophageal... and other conditions

United States, Australia, Belgium, France, Germany, Italy, Netherlands, Spain, United Kingdom
Tempest Therapeutics

Completed

TPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced Cancers

Sarcoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | Pancreatic Cancer | Squamous Cell Carcinoma of Head and Neck | Cholangiocarcinoma | Non-small Cell Lung Cancer | Urothelial Carcinoma | GastroEsophageal Cancer | Triple-Negative Breast Cancer | Metastatic Castration Resistant Prostate...

United States
MedImmune LLC

Completed

A Phase 1, Randomized, Placebo-controlled, Dose-escalation Safety Study of MEDI4212 in Subjects With IgE >= 30 IU/mL

Allergic Rhinitis | Healthy Volunteers | Atopic Dermatitis | Allergic Asthma

United States
University of Pittsburgh

Suspended

Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study (GREAT1)

Multiple Sclerosis | Diabetes Mellitus | Chronic Kidney Diseases | Gastritis | Rheumatoid Arthritis | Chronic Pain | Irritable Bowel Syndrome | Hepatitis | Inflammatory Bowel Diseases | Dyslipidemias | Chronic Disease | Celiac Disease | Cholecystitis | Crohn Disease | Cystic Fibrosis | Chronic Pancreatitis | NASH - Nonalcoholic... and other conditions

United States
Glenmark Specialty S.A.

Completed

Long Term Safety and Efficacy of Fixed Dose Combination GSP 301 Nasal Spray (NS) in the Treatment of Perennial Allergic Rhinitis (PAR) (GSP 301-303)

Perennial Allergic Rhinitis

United States
Novartis Pharmaceuticals

Terminated

Safety and Efficacy of Pimecrolimus Cream 1% in Atopic Disease Modification

Atopic Dermatitis

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study of Fluzone Vaccine Administered by Intradermal Route in Comparison With Standard Fluzone® in Adults

Influenza | Orthomyxoviridae Infection | Myxovirus Infection

United States, Puerto Rico
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Study of an Investigational Nasal Aerosol or Placebo in Children (Ages 4 to 11) With Perennial Allergic Rhinitis (PAR)

Allergic Rhinitis

United States
Inspire Medical Systems, Inc.

Active, not recruiting

Adherence and Outcome of Upper Airway Stimulation (UAS) for OSA International Registry

Obstructive Sleep Apnea

United States, Belgium, Germany, Netherlands, Switzerland
National Cancer Institute (NCI)

Completed

Depsipeptide in Unresectable Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Stage IV Squamous Cell Carcinoma of the Hypopharynx | Stage IV Squamous Cell Carcinoma of the Larynx | Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage IV Squamous Cell Carcinoma of the Oropharynx

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Long Term Safety and Efficacy Trial of Beclomethasone Dipropionate - Hydrofluoroalkane (BDP-HFA) 320 mcg in Allergic Rhinitis

Rhinitis, Allergic, Perennial

United States
Novo Nordisk A/S

Terminated

Effect of Inhaled Insulin (AERx® iDMS) on Blood Glucose Control in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

United States
Ascentage Pharma Group Inc.

Recruiting

Study of Safety, Pharmacokinetic and Efficacy of APG-5918 in Advanced Solid Tumors or Lymphomas

Sarcoma | Nasopharyngeal Carcinoma | Gastric Cancer | B Cell Lymphoma | Mesothelioma | Non Hodgkin Lymphoma | Ovarian Clear Cell Carcinoma | Epithelioid Sarcoma | Castrate Resistant Prostate Cancer

United States
Ontario Clinical Oncology Group (OCOG)
Pfizer

Completed

Dalteparin Low Molecular Weight Heparin for Primary Prophylaxis of Venous Thromboembolism in Brain Tumour Patients

Venous Thromboembolism | Brain Tumors

United States, Canada, Australia, Italy

Clinical Trials on Lung Injury in United Kingdom

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