Clinical Trials on Lung Neuroendocrine Neoplasm

Total 149557 results

Samsung Medical Center

Recruiting

The Molecular Screening Study for the Umbrella Trial (SUKSES) in Relapsed Small Cell Lung Cancer Patients [SUKSES-S]

Neuroendocrine Carcinoma | Small Cell Lung Cancers

Korea, Republic of
Peking Union Medical College Hospital
Harbin Medical University; The First Affiliated Hospital of Xiamen University

Recruiting

Chidamide Plus Sintilimab for Chemotherapy-refractory Advanced High-grade Neuroendocrine Neoplasm

Neuroendocrine Tumors | Neuroendocrine Carcinoma | Neuroendocrine Neoplasm | Neuroendocrine Tumor Grade 3

China
Fox Chase Cancer Center
Oryzon Genomics S.A.

Recruiting

Iadademstat in Combination With Paclitaxel in Relapsed/Refractory SCLC and Extrapulmonary High Grade NET

Small-cell Lung Cancer | Neuroendocrine Carcinoma

United States
Boehringer Ingelheim

Recruiting

DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers

Neuroendocrine Neoplasms

United States, Spain, Germany, Japan
National Cancer Institute (NCI)

Completed

A Phase I Study of Belinostat in Combination With Cisplatin and Etoposide in Adults With Small Cell Lung Carcinoma and Other Advanced Cancers

Small Cell Lung Carcinoma | Malignant Epithelial Neoplasms | Carcinoma Neuroendocrine

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer

Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Unresectable Pancreatic Adenocarcinoma | Metastatic... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab and Concurrent Chemoradiotherapy or Radiation Therapy in Treating Patients With Small Cell Lung Cancer

Neuroendocrine Neoplasm | Extensive Stage Small Cell Lung Carcinoma | Limited Stage Small Cell Lung Carcinoma

United States
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Not yet recruiting

Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by Dose Expansion Study in Participants With Neuroendocrine Carcinoma.

Neuroendocrine Carcinoma

China
King's College Hospital NHS Trust
Ampersand Health Ltd; Neuroendocrine Cancer UK

Recruiting

Mobile Application to Collect PRO Data in NET Patients

Neuroendocrine Neoplasms (Tumours)

United Kingdom
M.D. Anderson Cancer Center

Active, not recruiting

Stereotactic Body Radiation Therapy With or Without Nivolumab in Treating Patients With Stage I-IIA or Recurrent Non-small Cell Lung Cancer

Lung Non-Small Cell Squamous Carcinoma | Stage IIA Lung Cancer AJCC v8 | Neuroendocrine Carcinoma | Lung Atypical Carcinoid Tumor | Minimally Invasive Lung Adenocarcinoma | Lung Neuroendocrine Neoplasm | Stage I Lung Cancer AJCC v8 | Stage IA1 Lung Cancer AJCC v8 | Stage IA2 Lung Cancer AJCC v8 | Stage... and other conditions

United States
European Institute of Oncology

Recruiting

YOUNg Adults With Gastro-inteSTinal (GI) and nEuroendocrine canceRs. (YOUNGSTER)

Adenocarcinoma | Neuroendocrine Neoplasm

Italy
Tarveda Therapeutics

Completed

PEN-221 in Somatostatin Receptor 2 Expressing Advanced Cancers Including Neuroendocrine and Small Cell Lung Cancers

Neuroendocrine Tumors | Neuroendocrine Carcinoma | Carcinoma, Small Cell Lung

United States, United Kingdom
Roswell Park Cancer Institute
NeuroEndocrine Tumor Research Foundation (NETRF)

Recruiting

Survivin Long Peptide Vaccine in Treating Patients With Metastatic Neuroendocrine Tumors

Lung Atypical Carcinoid Tumor | Metastatic Pancreatic Neuroendocrine Tumor | Lung Typical Carcinoid Tumor

United States
Vyriad, Inc.
Mayo Clinic

Recruiting

Ph I/II Trial of Systemic VSV-IFNβ-NIS in Combination With Checkpoint Inhibitor Therapy in Patients With Select Solid Tumors

Solid Tumor | Non Small Cell Lung Cancer | Neuroendocrine Carcinoma

United States
Washington University School of Medicine
Exelixis

Recruiting

Cabozantinib in High Grade Neuroendocrine Neoplasms

High Grade Neuroendocrine Neoplasms

United States
Ipsen

Terminated

Efficacy and Safety of Lanreotide Autogel/ Depot 120 mg vs. Placebo in Subjects With Lung Neuroendocrine Tumours (SPINET)

Neuroendocrine Tumors in Lung

Canada, United States, Germany, France, United Kingdom, Netherlands, Spain, Denmark, Italy, Austria, Poland
National Cancer Institute (NCI)

Suspended

A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors

Advanced Solid Tumors | SCLC | HRD Cancer

United States
Novartis Pharmaceuticals
Eckert & Ziegler Radiopharma GmbH

Recruiting

A Prospective, Open-label Study of [68Ga]Ga-DOTA-TATE in Patients With Neuroendocrine Neoplasms (NENs) and Healthy Volunteers in Japan

Neuroendocrine Neoplasms

Japan
Fudan University

Recruiting

Neuroendocrine Transformation in RB1/TP53 Inactivated NSCLC

Non-small Cell Lung Cancer | Neuroendocrine Carcinoma | Histology Transformation

China
Harpoon Therapeutics

Recruiting

Study in Patients With Advanced Cancers Associated With Expression of DLL3

Neuroendocrine Carcinoma | Small-Cell Lung Cancer

United States
Translational Research in Oncology
Bayer; Novartis

Withdrawn

Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers (REFIT-MSS)

Soft Tissue Sarcoma | Small Cell Lung Carcinoma | Colorectal Neoplasms | Anal Squamous Cell Carcinoma | Malignant Pleural Mesothelioma | Castrate Resistant Prostate Cancer | Gastroenteropancreatic Neuroendocrine Neoplasm | Neuroendocrine Carcinoma of Prostate
National Cancer Institute (NCI)

Active, not recruiting

Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine Tumors

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Lung Neuroendocrine Neoplasm | Metastatic Malignant Neoplasm in the Brain | Metastatic Lung Small Cell Carcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, Triapine, to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Neuroendocrine Tumors

Metastatic Digestive System Neuroendocrine Neoplasm | Metastatic Neuroendocrine Tumor

United States
National Cancer Institute (NCI)

Completed

Cisplatin and Etoposide With or Without Veliparib in Treating Patients With Extensive Stage Small Cell Lung Cancer

Neuroendocrine Carcinoma | Small Cell Carcinoma | Extensive Stage Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer AJCC v7 | Large Cell Lung Carcinoma

United States
The University of Texas Health Science Center,...

Unknown

Hyperthermia/Thermal Therapy With Chemotherapy to Treat Inoperable or Metastatic Tumors (FR-WB-TT/che)

Small Cell Lung Cancer | Gastric Cancer | Non-Small Cell Lung Cancer | Neuroendocrine Cancer

United States
Vanderbilt-Ingram Cancer Center

Recruiting

Surgical Debulking Prior to Peptide Receptor Radionuclide Therapy in Well Differentiated Gastroenteropancreatic Neuroendocrine Tumors

Metastatic Digestive System Neuroendocrine Neoplasm | Metastatic Malignant Neoplasm in the Liver | Pancreatic Neuroendocrine Tumor G1 | Pancreatic Neuroendocrine Tumor G2 | Digestive System Neuroendocrine Tumor G1 | Digestive System Neuroendocrine Tumor G2

United States
M.D. Anderson Cancer Center

Suspended

A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers

Small Cell Lung Cancer | Hodgkin's Lymphoma | Cervical Carcinoma | Peritoneal Mesothelioma | Pleural Mesothelioma | Neuroendocrine Carcinomas | Microsatellite High Cancers | Extrapulmonary High Grade

United States
Xian-Jun Yu

Not yet recruiting

Neuroendocrine Neoplasm Based on Multi-omics Integrated Analysis

Neuroendocrine Neoplasm

China
University Hospital, Basel, Switzerland
University Hospital, Zürich; University Hospital Freiburg; Krebsforschung Schweiz... and other collaborators

Recruiting

177Lu-PP-F11N for Receptor Targeted Therapy and Imaging of Metastatic Thyroid Cancer. (Lumed)

Thyroid Cancer, Medullary | Neuroendocrine Tumor of the Lung Grade 1 and 2 | Neuroendocrine Tumor of the Thymus Grade 1 and 2 | Neuroendocrine Tumor GEP Grade 1-3

Switzerland
European Institute of Oncology

Recruiting

Definition of a Multiparametric Prognostic and Predictive System of Classification of NET G3 Patients (TAPIOCA)

Neuroendocrine Neoplasm

Italy
Biotheus Inc.

Recruiting

A Study of PM8002 Injection in Combination With Chemotherapy in Patients With NEN

Neuroendocrine Neoplasm

China
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of An Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Pancreatic Neuroendocrine Tumors

Neuroendocrine Neoplasm

United States
Jagiellonian University
Medical University Innsbruck; University Medical Centre Ljubljana; University... and other collaborators

Completed

Novel 99mTc-labeled Somatostatin Antaginosts in the Diagnostic Algotithm of Neuroendocrine Neoplasms (TECANT)

Neuroendocrine Tumors

Austria, Poland, Slovenia
Xiangya Hospital of Central South University

Unknown

A Study of 18F-AlF-NOTA-octreotide PET/CT for Imaging Neuroendocrine Neoplasms

Neuroendocrine Neoplasm

China
M.D. Anderson Cancer Center

Active, not recruiting

Niraparib and Dostarlimab for the Treatment of Small Cell Lung Cancer and Other High-Grade Neuroendocrine Carcinomas

Stage III Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Neuroendocrine Carcinoma | Stage IIIC Lung Cancer AJCC v8 | Lung Small Cell Carcinoma

United States
Peking University

Recruiting

Sintilimab Combined With IBI310 and Surufatinib for the Treatment of G3-NET and NEC

Neuroendocrine Neoplasm

China
Fudan University
D1 Medical Technology (Shanghai) Co., Ltd, China

Recruiting

Single-cell Sequencing and Establishment of Models in Neuroendocrine Neoplasm

Neuroendocrine Neoplasm

China
Tine Gregersen, MD

Recruiting

Dosimetry Based PRRT Versus Standard Dose PRRT With Lu-177-DOTATOC in NEN Patients (DOBATOC)

Neuroendocrine Neoplasm

Denmark
National Cancer Institute (NCI)

Completed

Pazopanib Hydrochloride in Treating Patients With Advanced Neuroendocrine Cancer

Lung Carcinoid Tumor | Metastatic Digestive System Neuroendocrine Tumor G1 | Pancreatic Polypeptide Tumor | Multiple Endocrine Neoplasia Type 1 | Pancreatic Glucagonoma | Pancreatic Insulinoma | Somatostatin-Producing Neuroendocrine Tumor | Recurrent Digestive System Neuroendocrine Tumor G1 | Recurrent... and other conditions

United States
Fudan University

Not yet recruiting

Nimotuzumab in EGFR Highly Expressed Pancreatic Neuroendocrine Neoplasms

Pancreatic Neuroendocrine Neoplasm

China
Rahul Aggarwal
Janssen Scientific Affairs, LLC

Active, not recruiting

Apalutamide Plus Cetrelimab in Patients With Treatment-Emergent Small Cell Neuroendocrine Prostate Cancer

Prostate Cancer | Small Cell Carcinoma | Small Cell Neuroendocrine Carcinoma

United States
Guangdong Zhongsheng Pharmaceutical Co., Ltd.

Unknown

A Phase 1 Study of ZSP1602 in Participants With Advanced Solid Tumors

Small Cell Lung Cancer | Glioblastoma | Medulloblastoma | Neuroendocrine Neoplasm | Basal Cell Carcinoma | Adenocarcinoma of Esophagogastric Junction

China
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Observational Study on GEP-and Pulm-NET Treated at FPG (ETNA-FPG)

Neuroendocrine Tumors | Pulmonary Neuroendocrine Neoplasm | Gep Net

Italy
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Recruiting

A Trial Aiming to Assess the Safety and Activity of the Combination of Cabozantinib Plus Lanreotide in GEP and NET (LOLA)

Neuroendocrine Tumors | Metastatic Well Differentiated Neuroendocrine Neoplasm

Italy
Excel Diagnostics and Nuclear Oncology Center

Withdrawn

Phase-II Study of Lu177DOTATOC in Adults With STTR(+)Pulmonary, Pheochromocytoma, Paraganglioma, Unknown Primary, Thymus NETs (PUTNET), or Any Other Non-.GEP-NET. (PUTNET)

Neuroendocrine Tumors | Pheochromocytoma | Paraganglioma | Unknown Primary Tumors | Pulmonary Neuroendocrine Neoplasm | Thymus Carcinoid | Neuroendocrine Skin Carcinoma | Neuroendocrine Breast Tumor | Neuroendocrine Carcinoma Metastatic | Neuroendocrine Neoplasm of Ovary

United States
Catholic University of the Sacred Heart

Completed

Endoscopic Ultrasound-guided RadioFrequency Ablation for the Treatment Pancreatic NeuroEndocrine Neoplasms (RAPNEN)

Neuroendocrine Tumors | Neuroendocrine Carcinoma | Pancreas Neoplasm | Neuroendocrine Tumor Gastrointestinal, Hormone-Secreting

Italy
The Christie NHS Foundation Trust
Pancreatic Cancer UK

Completed

Pancreatic Cancer Dietary Assessment Study (PanDA)

Pancreas Adenocarcinoma | Pancreatic Neoplasm | Malignant Neoplasm of Pancreas | Well-Differentiated Neuroendocrine Carcinoma

United Kingdom
Nicholas Fidelman, MD
Merck Sharp & Dohme LLC; BTG International Inc.

Active, not recruiting

Pembrolizumab With Liver-Directed or Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors and Liver Metastases

Neuroendocrine Neoplasm | Metastatic Malignant Neoplasm in the Liver

United States
National Cancer Institute (NCI)

Recruiting

Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

Advanced Extrapulmonary Neuroendocrine Carcinoma | Metastatic Extrapulmonary Neuroendocrine Carcinoma | Recurrent Extrapulmonary Neuroendocrine Carcinoma | Unresectable Extrapulmonary Neuroendocrine Carcinoma

United States
Fundación de investigación HM
Syntax for Science, S.L

Recruiting

A Clinical Study to Assess the Combination of Two Drugs (177Lu-DOTATATE and Nivolumab) in Neuroendocrine Tumours

Neuroendocrine Tumours (NET) | Neuroendocrine Carcinomas (NEC)

Spain

Clinical Trials on Lung Neuroendocrine Neoplasm

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