Clinical Trials on MGMT-Methylated Glioblastoma in New Zealand

Total 316 results

National Cancer Institute (NCI)

Suspended

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

Recurrent Glioblastoma, IDH-Wildtype | MGMT-Methylated Glioblastoma | Recurrent MGMT-Methylated Glioblastoma

United States
NYU Langone Health

Completed

Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated Glioblastoma

GBM | MGMT-unmethylated Glioblastoma (GBM)

United States
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma

Gliosarcoma | MGMT-Unmethylated Glioblastoma

United States
National Cancer Institute (NCI)

Recruiting

Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer

Glioblastoma | Gliosarcoma | Recurrent Glioblastoma | MGMT-Unmethylated Glioblastoma

United States
Northern Sydney and Central Coast Area Health Service
Merck KGaA, Darmstadt, Germany

Unknown

Temozolomide and Procarbazine With Cilengitide for Patients With Glioblastoma Multiforme Without Methylation of the MGMT Promoter Gene (ExCentric)

Newly Diagnosed Non Methylated Glioblastoma Multiforme Grade 4

Australia
Waikato Hospital
Wellington Hospital

Recruiting

Metabolic Therapy Program In Conjunction With Standard Treatment For Glioblastoma

Glioblastoma

New Zealand
Telix International Pty Ltd

Recruiting

131I-TLX-101 for Treatment of Newly Diagnosed Glioblastoma (IPAX-2) (IPAX-2)

Glioblastoma | Glioblastoma Multiforme | Neoplastic Disease

Australia, Austria, Netherlands, New Zealand
Neurological Surgery, P.C.

Unknown

Hyperbaric Hyperoxygenation With Radiotherapy and Temozolomide in Adults With Newly Diagnosed Glioblastoma (HBO)

Gliosarcoma | Glioblastomas

United States
Jazz Pharmaceuticals
Yale University

Completed

TAU-2014-1: Mibefradil and Hypofractionated Re-Irradiation Therapy in Recurrent GBM

Glioblastoma Multiforme (GBM)

United States
Northwell Health

Completed

Super-Selective Intraarterial Cerebral Infusion of Cetuximab (Erbitux) for Treatment of Relapsed/Refractory GBM and AA

GBM | Anaplastic Astrocytoma | Glioblastoma Multiforme (GBM) | ANAPLASTIC ASTROCYTOMA (AOA)

United States
Northwell Health

Recruiting

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

Glioblastoma | Brain Cancer | Glioblastoma Multiforme | GBM | Glioma, Malignant | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult

United States
Celldex Therapeutics

Completed

A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma (ReACT)

Glioblastoma | Gliosarcoma | Recurrent Glioblastoma | Small Cell Glioblastoma | Giant Cell Glioblastoma | Glioblastoma With Oligodendroglial Component | Relapsed Glioblastoma

United States
TVAX Biomedical
FDA Office of Orphan Products Development

Recruiting

Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme of Brain

United States
NuvOx LLC

Recruiting

A Phase II Double-blind, RandomizEd, Prospective, Placebo Controlled STudy of NanO2TM Combined With Radiation and Temozolomide in Patients With Newly-diagnosed Glioblastoma multiformE: (RESTORE)

Glioblastoma Multiforme

United States
Orbus Therapeutics, Inc.

Recruiting

Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma

Glioblastoma | Glioblastoma Multiforme | GBM | Glioblastoma, IDH-wildtype | Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype

United States
New York Presbyterian Brooklyn Methodist Hospital

Recruiting

MRI Predictors of Response to Tumor Treating Fields

Glioblastoma Multiforme

United States
Hackensack Meridian Health
NovoCure Ltd.

Completed

NovoTTF-200A and Temozolomide Chemoradiation for Newly Diagnosed Glioblastoma

Glioblastoma, Adult

United States
Dartmouth-Hitchcock Medical Center

Completed

Phase II Feasibility Study of Dendritic Cell Vaccination for Newly Diagnosed Glioblastoma Multiforme

Glioblastoma Multiforme

United States
Dartmouth-Hitchcock Medical Center
Genentech, Inc.

Completed

Exploratory Study of the Modulation of the Immune System by VEGF Blockade in Patients With Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme

United States
Yale University

Terminated

Early Detection of Glioblastoma Multiforme (GBM) Treatment Responses Using Multiple Magnetic Resonance Modalities

Glioblastoma Multiforme

United States
Northwell Health
Feinstein Institute for Medical Research

Recruiting

Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States
Northwell Health

Suspended

Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab Plus Carboplatin For Treatment Of Relapsed/Refractory GBM And Anaplastic Astrocytoma

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States
Northwell Health

Completed

Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab)

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States
Northwell Health
Feinstein Institute for Medical Research; Hofstra North Shore

Completed

Super-Selective Intraarterial Cerebral Infusion Of Temozolomide (Temodar) For Treatment Of Newly Diagnosed GBM And AA

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States
Stony Brook University
Genentech, Inc.

Recruiting

Atezolizumab and Pre-Surgical Brain Radiation Therapy for Glioblastoma Multiforme

Glioblastoma Multiforme

United States
Aivita Biomedical, Inc.

Active, not recruiting

Autologous Dendritic Cells Loaded With Autologous Tumor Associated Antigens for Treatment of Newly Diagnosed Glioblastoma

Newly Diagnosed Glioblastoma

United States
Shuttle Pharmaceuticals, Inc.

Not yet recruiting

Ropidoxuridine as a Radiosensitizer in Newly Diagnosed IDH-Wildtype Glioblastoma With Unmethylated MGMT Promoter

Glioblastoma, IDH-wildtype

United States
Celldex Therapeutics

Completed

Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma (ACT IV)

Glioblastoma | Gliosarcoma | Small Cell Glioblastoma | Giant Cell Glioblastoma | Glioblastoma With Oligodendroglial Component

United States, Canada, Australia, Israel, Taiwan, United Kingdom, Belgium, France, Spain, Germany, Austria, Brazil, Colombia, Czechia, Greece, Hungary, India, Italy, Mexico, Netherlands, New Zealand, Peru, Switzerland, Thailand
Northwell Health
Feinstein Institute for Medical Research

Completed

Repeated Super-Selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Newly Diagnosed GBM

Brain Tumor | Glioblastoma Multiforme

United States
Boston Scientific Corporation

Recruiting

A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM (FRONTIER)

Glioblastoma Multiforme | Recurrent Glioblastoma

United States
Celularity Incorporated

Withdrawn

CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Type (CYNK001GBM02)

Glioblastoma | Glioblastoma Multiforme | Giant Cell Glioblastoma | Astrocytoma, Grade IV

United States
Northwell Health

Recruiting

Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma

Glioblastoma | Brain Cancer | Glioblastoma Multiforme | High Grade Glioma | GBM | Glioma, Malignant | Glioblastoma Multiforme, Adult

United States
Chembrain LTD
University of Oulu; Jyväskylä Central Hospital; Apollo Hospital, New Delhi, India

Active, not recruiting

The Efficacy and Safety of Brain-targeting Immune Cells (EGFRvIII-CAR T Cells) in Treating Patients With Leptomeningeal Disease From Glioblastoma. Administering Patients EGFRvIII -CAR T Cells May Help to Recognize and Destroy Brain Tumor Cells in Patients (CARTREMENDOUS)

Glioblastoma | Glioblastoma Multiforme | Glioma, Malignant

Finland, India
Neonc Technologies, Inc.

Recruiting

Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma

Glioblastoma Multiforme

United States
NuvOx LLC
The Alfred

Completed

The Effects of NVX-108 as a Radiation Sensitizer in Glioblastoma (GBM)

Glioblastoma Multiforme

Australia
MimiVax, LLC
Translational Drug Development; Merit

Active, not recruiting

SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE) (SURVIVE)

Newly Diagnosed Glioblastoma

United States
Northwell Health

Recruiting

Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)

Glioma | Glioblastoma | Brain Cancer | Glioblastoma Multiforme | High Grade Glioma | GBM | Glioma, Malignant | Glioblastoma Multiforme of Brain

United States
Northwell Health

Suspended

Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM)

Glioma | Glioblastoma | Brain Cancer | Glioblastoma Multiforme | GBM | Glioma, Malignant | Glioblastoma Multiforme of Brain

United States
Cortice Biosciences, Inc.

Terminated

Safety & Efficacy Study of TPI 287 + Avastin in Adults With Glioblastoma That Progressed Following Prior Avastin Therapy

Glioblastoma Multiforme

United States
Weill Medical College of Cornell University
Eisai Inc.

Withdrawn

Examination of Changes on Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy (MRS) in Patients Who Receive Gliadel Wafers During Initial Surgery for Glioblastoma Multiforme. Response or Failure to Gliadel Wafers for Subjects With Glioblastoma Multiforme. (Gliadel-MRS)

Glioblastoma Multiforme | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

United States
Northwell Health
Genentech, Inc.

Completed

Oral Tarceva Study for Recurrent/Residual Glioblastoma Multiforme and Anaplastic Astrocytoma

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States
Stony Brook University
Garnett McKeen Laboratory Inc.

Completed

Dose Evaluation Safety STudy IN Individuals With Astrocytoma Taking PolyMVA (DESSTINI_A)

Glioblastoma Multiform (Grade IV Astrocytoma)

United States
INSYS Therapeutics Inc

Completed

Histologic Effect/Safety of Pre/Post-Operative IL13-PE38QQR in Recurrent Resectable Supratentorial Malignant Glioma Patients

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Mixed Oligoastrocytoma | Malignant Astrocytoma

United States
VBI Vaccines Inc.

Recruiting

Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects

Glioblastoma Multiforme

United States
Cortice Biosciences, Inc.

Suspended

Dose-Escalation Study of TPI 287 + Avastin Followed by Randomized Study of the Same Versus Avastin for Glioblastoma

Glioblastoma Multiforme

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fields

Glioblastoma | Recurrent Glioblastoma | Skin Toxicity

United States
Photolitec LLC
National Cancer Institute (NCI); Roswell Park Cancer Institute

Recruiting

Intracavitary Photodynamic Therapy as an Adjuvant to Resection of Glioblastoma or Gliosarcoma Using IV Photobac®

Glioblastoma Multiforme of Brain | Glioma, Sarcomatous

United States
Precision Life Sciences Group

Completed

A Study of ICT-107 Immunotherapy in Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme

United States
Gilead Sciences

Terminated

Efficacy Study of CYT997 in Combination With Carboplatin in Glioblastoma

Glioblastoma Multiforme

Australia
Northwell Health

Recruiting

Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM (CAPTEM)

Cancer | Glioblastoma | Brain Cancer | Brain Tumor | Brain Tumor, Primary | Brain Tumor Adult | Glioma of Brain | Glioblastoma, Adult | Glioblastoma Multiforme (GBM)

United States

Clinical Trials on MGMT-Methylated Glioblastoma in New Zealand

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