Clinical Trials on MGMT-Unmethylated Glioblastoma

Total 1678 results

Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Clinical Trial of the ATM-Inhibitor WSD0628 in Combination With Radiation Therapy for Recurrent Brain Tumors

Glioblastoma

United States
RasCal Therapeutics, Inc.

Recruiting

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

Glioblastoma | Pancreatic Cancer | Lung Cancer | Colon Cancer | Advanced Malignant Solid Neoplasm | RAS Mutation

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); BerGenBio ASA

Terminated

AXL Inhibitor BGB324 in Treating Participants With Recurrent Glioblastoma Undergoing Surgery

Brain and Central Nervous System Tumors

United States
Sumitomo Pharma Co., Ltd.

Completed

A Study of DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade Gliomas

Glioblastoma | Diffuse Intrinsic Pontine Glioma

Japan
Jonsson Comprehensive Cancer Center

Completed

Sirolimus in Treating Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Bevacizumab and Sorafenib in Treating Patients With Recurrent Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Terminated

O(6)-Benzylguanine and Temozolomide in Treating Patients With Glioblastoma Multiforme That Did Not Respond to Previous Temozolomide and Radiation Therapy

Brain and Central Nervous System Tumors

United States
The Cleveland Clinic

Unknown

Erlotinib in Treating Patients With Recurrent or Progressive Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Atlantic Health System

Unknown

Combination Chemotherapy in Treating Patients With Recurrent Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Withdrawn

Temozolomide Plus Carboplatin in Treating Patients With Recurrent Glioblastoma Multiforme

Brain and Central Nervous System Tumors
Ludwig-Maximilians - University of Munich

Unknown

Combined O-(2-[18F]Fluoroethyl)-L-tyrosine (FET) Positron Emission Tomography (PET) and Simultaneous Magnetic Resonance Imaging (MRI) Follow-up in Re-irradiated Recurrent Glioblastoma Patients

Glioma | Neoplasms by Histologic Type | Glioblastoma | Astrocytoma | Neoplasms, Neuroepithelial | Neuroectodermal Tumors | Neoplasms, Nerve Tissue | Central Nervous System Neoplasms | Nervous System Neoplasms

Germany
European Organisation for Research and Treatment...

Completed

Epothilone ZK-219477 in Treating Patients With Recurrent Glioblastoma

Brain and Central Nervous System Tumors

Switzerland
Kyrre Eeg Emblem

Enrolling by invitation

Imaging Perfusion Restrictions From Extracellular Solid Stress - An Open-label Losartan Study (ImPRESS)

Glioblastoma | Brain Metastases

Norway
The University of Texas Health Science Center at...
Gilead Sciences

Active, not recruiting

Neuro/Sacituzumab Govitecan/Breast Brain Metastasis/Glioblastoma/Ph 0

Glioblastoma

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

A Phase I Clinical Trial of Bevacizumab Injection

Cervical Cancer | Glioblastoma | Ovarian Cancer | Lung Cancer | Rectal Cancer

China
Dana-Farber Cancer Institute
Merck Sharp & Dohme LLC

Completed

A Pilot Surgical Trial To Evaluate Early Immunologic Pharmacodynamic Parameters For The PD-1 Checkpoint Inhibitor, Pembrolizumab (MK-3475), In Patients With Surgically Accessible Recurrent/Progressive Glioblastoma

Brain Cancer

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Terminated

Radiation Therapy Followed by Bleomycin in Treating Adult Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy and Tamoxifen in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States, Canada
Jonsson Comprehensive Cancer Center

Completed

Bevacizumab, Temozolomide, and External Beam Radiation Therapy as First-Line Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

Brain and Central Nervous System Tumors

United States
Massachusetts General Hospital
National Cancer Institute (NCI)

Terminated

MRI Scans in Evaluating the Effects of Radiation Therapy and Chemotherapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Glioma

Brain and Central Nervous System Tumors

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIII

Glioblastoma | Brain Cancer | Malignant Glioma | Gliosarcoma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Hydroxychloroquine, Radiation, and Temozolomide Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Northwestern University
M.D. Anderson Cancer Center

Completed

Bevacizumab and Erlotinib After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

Brain and Central Nervous System Tumors

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Gadolinium Texaphyrin Plus Radiation Therapy in Treating Patients With Supratentorial Glioblastoma Multiforme

Brain and Central Nervous System Tumors
Translational Research Center for Medical Innovation...
Department of Nuerosurgery, Osaka Medical College

Completed

Boron Neutron Capture Therapy, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

Japan
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Completed

Temozolomide, Thalidomide, and Celecoxib Following Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Irinotecan Plus Radiation Therapy Followed By Chemotherapy in Treating Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors
Barrett Cancer Center

Unknown

Radiation Therapy Plus Hyperbaric Oxygen in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Biological Therapy in Treating Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Cancer Research UK

Terminated

Boron Phenylalanine With or Without Mannitol in Treating Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United Kingdom
Duke University
National Cancer Institute (NCI)

Completed

Temozolomide in Treating Adults With Newly Diagnosed Primary Malignant Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Motexafin Gadolinium Plus Radiation Therapy to the Brain in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
NYU Langone Health

Completed

Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Glioblastoma Multiforme or Brain Stem Tumors

Brain and Central Nervous System Tumors

United States
Assistance Publique - Hôpitaux de Paris
Association de Neuro-Oncologues d'Expression Francaise

Completed

Temozolomide in Elderly Patients With KPS < 70 (TAG)

Glioblastoma | Primary Brain Tumor

France
IRCCS San Raffaele

Recruiting

Glutamate Excitotoxicity and Its Role in Glioblastoma Biology

Brain Tumor, Primary

Italy
SonoClear AS

Recruiting

SonoClear Acoustic Coupling Fluid (ACF) Mimicking Brain Tissue

Glioblastoma | High Grade Glioma | Low-grade Glioma | Brain Tumour

Germany, Slovakia, Italy
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Dalteparin and Radiation Therapy in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas

Glioblastoma | Brain Tumor | Anaplastic Glioma

United States
BeiGene USA, Inc.

Completed

A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma

Brain and Central Nervous System Tumors

United States, Netherlands, Switzerland
National Cancer Institute (NCI)

Completed

Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma

Glioblastoma | Astrocytoma | Brain Tumor | Gliosarcoma | Astroglioma

United States
Case Comprehensive Cancer Center

Terminated

Radiosurgery Plus Bevacizumab in Glioblastoma

Glioblastoma | Brain Tumor | Gliosarcoma

United States
National Institute of Neurological Disorders and...

Withdrawn

Bevacizumab With or Without Surgery for Adult Glioblastomas

Glioblastoma | Brain Neoplasm
Abramson Cancer Center of the University of Pennsylvania
National Cancer Institute (NCI)

Completed

Iodine I 131 Monoclonal Antibody TNT-1/B in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Direct Therapeutics

Unknown

Carmustine in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Center for Molecular Medicine

Unknown

Phosphorus 32 in Treating Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Neurocrine Biosciences

Completed

NBI-3001 Followed by Surgery in Treating Patients With Recurrent Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Novartis Pharmaceuticals

Completed

AEE788 and Everolimus in Treating Patients With Recurrent or Relapsed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
European Organisation for Research and Treatment...

Completed

Acridine Carboxamide in Treating Patients With Recurrent Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United Kingdom

Clinical Trials on MGMT-Unmethylated Glioblastoma

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