Clinical Trials on Macula Abnormality

Total 2759 results

Pfizer

Completed

Observational Study Of The Long-Term Effect Of Macugen In Patients With Wet Age-Related Macular Degeneration (MACULA)

Macular Degeneration | Age-related Macular Degeneration | Neovascular Macular Degeneration
Assiut University

Recruiting

Single-stage Correction of Acute Angle Coxa Vara (Coxavara)

Coxa Vara

Egypt
University Hospital, Lille

Recruiting

Transhepatic Echography for Fluid Responsiveness After Cardiovascular Surgery (THEFRACS)

Fluid Overload | Fluid Responsiveness | Venous Congestion | Cardiovascular Surgery | Inferior Vena Cava Abnormality

France
Agricultural University of Athens

Completed

Acute Effects of Juice Consumption With Biofunctional Compounds and Probiotics on Glucose Metabolism

Appetite Disorders | Potential Abnormality of Glucose Tolerance

Greece
VA Office of Research and Development

Recruiting

Active AMD Study to Improve Function in Veterans

Age Related Macular Degeneration (AMD)

United States
Ain Shams University

Recruiting

Comparative Study Between IVI of Ranibizumab With and Without Prior ACP in Patients With DME Using OCT-A

Diabetic Macular Edema

Egypt
Oslo University Hospital

Not yet recruiting

Photobiomodulation for Dry Age Related Macula Degeneration

Age-Related Macular Degeneration | Photobiomodulation
Shin Kong Wu Ho-Su Memorial Hospital

Recruiting

Maximum Treatment Interval With Aflibercept T&E

Neovascular Age-related Macular Degeneration

Taiwan
Novartis Pharmaceuticals

Recruiting

Effectiveness of Brolucizumab in Pre-treated Patients With nAMD in the Real-world Setting

Neovascular Age-related Macular Degeneration

United Arab Emirates
Berner Augenklinik
medignition AG

Enrolling by invitation

Comparison of Rapid Aflibercept and Brolucizumab T&E in wAMD (SPARROW)

Wet Age-related Macular Degeneration

Switzerland
Bio-Thera Solutions

Completed

Clinical Study of the Safety and Efficacy of BAT5906 Injection

Diabetic Macular Edema

China
Texas Retina Associates
The Emmes Company, LLC

Completed

One Year Trial Evaluating Safety of Ozurdex With Eylea (COED)

Diabetic Macular Edema

United States
Shanghai Biomabs Pharmaceutical Co., Ltd.

Completed

Phase I Study to Compare CMAB818 Injection and Lucentis® in Patients With Wet AMD

Wet Age-related Macular Degeneration

China
Novartis Pharmaceuticals

Completed

Treatment Patterns With Brolucizumab in Germany - a Retrospective Cohort Study Based on Longitudinal Prescription Data: REALIZE Study

Neovascular Age-related Macular Degeneration

Portugal
Beijing Hospital

Completed

Combination of Intravitreal Ranibizumab With or Without Micropulse Laser for the Treatment of DME

Diabetic Macular Edema

China
Michel Giunta
Bayer

Active, not recruiting

Treat and Extend Analysis Trial With Aflibercept in Wet-AMD

Wet Age-related Macular Degeneration

Canada
Frank G. Holz
Radboud University Medical Center; Bayer; Hoffmann-La Roche; Novartis Pharmaceuticals and other collaborators

Active, not recruiting

Development of Novel Clinical Endpoints in Intermediate AMD (MACUSTAR)

Age Related Macular Degeneration (AMD)

Germany, Italy, Netherlands, United Kingdom, France, Portugal, Denmark
Qilu Pharmaceutical Co., Ltd.

Completed

A Study to Compare QL1207 to Eylea® in Subjects With Wet Age-related Macular Degeneration (wAMD)

Wet Age-related Macular Degeneration

China
Novartis Pharmaceuticals

Completed

Real-world Evaluation of Brolucizumab for the Treatment of Neovascular (Wet) Age-related Macular Degeneration (AMD) (IRIS Study)

Age-related Macular Degeneration (AMD)

United States
Novartis Pharmaceuticals

Completed

Evaluation of Number of Patient Eyes That Remained on or Switched to Anti-VEGF Treatment After Initiation of Broluciumab

Age-related Macular Degeneration (AMD)

United States
Bioeq GmbH

Completed

Efficacy and Safety of the Biosimilar Ranibizumab FYB201 in Comparison to Lucentis in Patients With Neovascular Age-related Macular Degeneration (COLUMBUS-AMD)

Age-related Macular Degeneration (AMD)

France, Italy, Poland, Russian Federation, Spain, United Kingdom, Germany, Hungary, Ukraine, Austria, Czechia, Israel
i-Lumen Scientific, Inc.

Withdrawn

Microcurrent Stimulation for Dry Age-related Macular Degeneration (i-SIGHT)

Dry Age-related Macular Degeneration
Alkahest, Inc.

Completed

Evaluate the Effects and Safety of ALK4290 in Patients With Newly Diagnosed Wet Age-Related Macular Degeneration

Wet Age-related Macular Degeneration

Hungary
Vienna Institute for Research in Ocular Surgery

Completed

Intraretinal Cystoid Changes After Vitrectomy With Membrane Peeling

Macular Edema, Cystoid

Austria
Southeast Retina Center, Georgia

Completed

IAI for Persistent DME After Treatment With Bevacizumab And Ranibizumab (ROTATED)

Diabetic Macular Edema

United States
Andrew Moshfeghi, MD, MBA
Case Western Reserve University

Withdrawn

Evaluation of Bromocriptine, Metoprolol and Tamsulosin in Eyes With Non-Central DME

Diabetic Macular Edema
Alcon, a Novartis Company

Completed

LHA510 Proof-of-Concept Study as a Maintenance Therapy for Patients With Wet Age-Related Macular Degeneration

Exudative Age-Related Macular Degeneration

United States
Tennessee Retina
Regeneron Pharmaceuticals

Unknown

Two-week Retreatment Interval Study for Treated Age-related Macular Degeneration Refractory to Monthly Aflibercept (TRISTAR)

Neovascular Age-related Macular Degeneration

United States
Chinese Academy of Sciences
The First Affiliated Hospital of Zhengzhou University

Unknown

Treatment of Dry Age Related Macular Degeneration Disease With Retinal Pigment Epithelium Derived From Human Embryonic Stem Cells

Dry Age-related Macular Degeneration

China
CHA University

Unknown

The Safety and Tolerability of Sub-retinal Transplantation of SCNT-hES-RPE Cells in Patients With Advanced Dry AMD

Dry Age Related Macular Degeneration

Korea, Republic of
Maisonneuve-Rosemont Hospital
Novartis; Foundation Fighting Blindness; Fonds de recherche en ophtalmologie... and other collaborators

Completed

Omega-3 Supplementation and Vitreal VEGF Levels in Wet-AMD

Exudative Age Related Macular Degeneration

Canada
Novartis Pharmaceuticals

Terminated

A Prospective, Observational, Multicentre, 2 Year Study Evaluating the Use of Eylea (Aflibercept) for the Treatment of Neovascular (Wet) Age-related Macular Degeneration in UK NHS Opthalmology Clinics

Wet Age-related Macular Degeneration

United Kingdom
PanOptica, Inc.

Completed

Phase 1 Study of Topical Ocular PAN-90806 for Neovascular AMD

Age-Related Macular Degeneration (AMD)

United States
Palmetto Retina Center, LLC

Unknown

Treat and Extend Therapy Study Using Intravitreal Aflibercept for Patients Exited From Protocol VGFT-OD 0910 (RANGE)

Exudative Age-related Macular Degeneration

United States
Ohr Pharmaceutical Inc.

Completed

Efficacy and Safety of Squalamine Lactate Eye Drops in Subjects With Neovascular (Wet) Age-related Macular Degeneration (AMD)

Neovascular Age Related Macular Degeneration

United States
Allergan
Molecular Partners AG

Terminated

Study of MP0112 Intravitreal Injection in Patients With Wet Age Related Macular Degeneration

Wet Age-Related Macular Degeneration

Switzerland, France, Czech Republic
Lawson Health Research Institute

Completed

Intravitreal Injection Anesthesia - Comparison of Different Topical Agents

Age-Related Macular Degeneration (AMD)

Canada
The Ludwig Boltzmann Institute of Retinology and...

Completed

The Spectralis-Cirrus Study

Exudative Age Related Macular Degeneration

Austria
Oculis
ICON plc

Recruiting

Study of the Efficacy and Safety of OCS-01 Eye Drops in Subjects With Diabetic Macular Edema (DIAMOND-2)

Diabetic Macular Edema

United States
Novartis Pharmaceuticals

Not yet recruiting

Post Marketing Study to Evaluate the Safety and Effectiveness of Brolucizumab in Patients With Diabetic Macular Edema.

Diabetic Macular Edema
Yeungnam University College of Medicine
Novartis

Not yet recruiting

Prospective triAl of Modified Treat-and-extend Regimens With BroLucizumab in pachychOroid Neovasculopathy (PABLO)

Age-Related Macular Degeneration | Pachychoroid Neovasculopathy
Hoffmann-La Roche

Recruiting

A Study to Investigate Vamikibart in Participants With Uveitic Macular Edema (Meerkat)

Uveitic Macular Edema

United States, Korea, Republic of, United Kingdom, China, Netherlands, Canada, Israel, Austria, Brazil, Italy, Taiwan, Poland, Portugal, Mexico
Vista Klinik

Not yet recruiting

Intravitreal Faricimab in Diabetic Macular Edema With Limited Response to Aflibercept

Diabetic Macular Edema
Chinese University of Hong Kong

Recruiting

Comparing Conventional Grid Laser Photocoagulation and Subthreshold Micropulse Laser in Diabetic Macular Edema Using OCT Angiography

Diabetic Macular Edema

China
Laboratorios Sophia S.A de C.V.

Recruiting

Clinical Study to Evaluate PRO-169 for Diabetic Macular Edema (PRO-169)

Diabetic Macular Edema

Colombia, Mexico
Centre Hospitalier Universitaire Dijon

Recruiting

Medico Economic Evaluation of Fluocinolone Acetonide Implant Versus Dexametheasone Implant in Resistant Diabetic Macular Oedema (EMMA)

Diabetic Macular Edema

France
Uptown Eye Specialists

Not yet recruiting

Ozurdex in Suboptimal Diabetic Macular Edema Patients (DME)

Diabetic Macular Edema
Hospices Civils de Lyon

Recruiting

Pilot and Phase 2 Study of the Efficacy of a Treatment Protocol With Dexamethasone Implant Loading Dose in Patients With Diabetic Macular Edema (LOADEX) (LOADEX)

Diabetic Macular Edema

France
Moorfields Eye Hospital NHS Foundation Trust
University College, London

Recruiting

A Study Of Implantation Of Retinal Pigment Epithelium In Subjects With Acute Wet Age Related Macular Degeneration

Age Related Macular Degeneration

United Kingdom
Asociación para Evitar la Ceguera en México

Withdrawn

Intravitreal Bevacizumab (Avastin) for Pseudophakic Macular Edema (PME)

Cystoid Macular Edema

Mexico

Clinical Trials on Macula Abnormality

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