Example: Heart Attack

Clinical Trials on Malformations of Cortical Development

Total 91 results

    • NCT02451696
      Completed
      A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD
      Conditions: Epilepsy; Tuberous Sclerosis Complex; Focal Cortical Dysplasia
    • NCT00687024
      Completed
      Determining the Extent of Diffusion Tensor Abnormalities in Focal Cortical Dysplasia
      Conditions: Focal Cortical Dysplasia; Epilepsy
    • NCT03198949
      Unknown status
      A Study Investigating the Anti-epileptic Efficacy of Afinitor (Everolimus) in Patients With Refractory Seizures Who Have Focal Cortical Dysplasia Type II (FCD II)
      Conditions: Epilepsy and Focal Cortical Dysplasia II
    • NCT02261753
      Terminated
      Evaluating Dietary Intervention Before surgicaL Treatment for Epilepsy
      Conditions: Cortical Dysplasia
    • NCT02890641
      Recruiting
      Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies
      Conditions: Cortical Dysplasia-Focal Epilepsy Syndrome
    • NCT00041600
      Recruiting
      Human Epilepsy Genetics--Neuronal Migration Disorders Study
      Conditions: Epilepsy; Seizures; Cognition Disorders; Neuronal Migration Disorders
    • NCT04344626
      Recruiting
      Use of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy Surgery
      Conditions: Epilepsy; Focal Cortical Dysplasia; Tuberous Sclerosis; Hemimegalencephaly; Polymicrogyria; Rasmussen Encephalitis; Sturge-Weber Syndrome; Gliosis; Stroke; Tumor, Brain
    • NCT02654340
      Recruiting
      Biomarkers for Tuberous Sclerosis Complex (BioTuScCom)
      Conditions: Hypomelanotic Macules; Facial Angiofibroma; Shagreen Patches; Ungual Fibromas; Cortical Dysplasia; Cardiac Rhabdomyoma; Lymphangioleiomyomatosis; Renal Angiomyolipoma; Subependymal Giant Cell Astrocytoma
    • NCT00552045
      Completed
      Epilepsy Phenome/Genome Project
      Conditions: Epilepsy; Localization-related Epilepsy; Infantile Spasms; Lennox-Gastaut Syndrome; Polymicrogyria; Periventricular Heterotopias
    • NCT03321240
      Recruiting
      Study of Predictive Biomarkers for Rational Management of Drug-resistant Epilepsy Associated With Focal Cortical Dysplasia
      Conditions: Refractory Epilepsy; Focal Epilepsy; Focal Cortical Dysplasia
    • NCT00686530
      Withdrawn
      Comparison of Abnormal Cortical Development in Brain Malformations on Postmortem Imaging With Autopsy
      Conditions: Brain Malformation
    • NCT04816175
      Recruiting
      Intensive Therapy for Children With Microcephaly, Hyperkinetic Movements, or Global Developmental Delay
      Conditions: Microcephaly; Hyperkinesis With Developmental Delay; Global Developmental Delay
    • NCT03255369
      Unknown status
      Vertical Exposure to Zika Virus and Its Consequences for Child Neurodevelopment (ZIKVIRUSIFF)
      Conditions: ZIKA VIRUS INFECTION; Child Development; Microcephaly
    • NCT03548779
      Enrolling by invitation
      North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2
      Conditions: Epilepsy; Seizure; Neuromuscular Diseases; Brain Malformation; Intellectual Disability; Autism Spectrum Disorder; Hypotonia; Inborn Errors of Metabolism; Movement Disorders; Genetic Disease; Development Delay; Chromosome Abnormality; Hearing Loss; Dysmorphic Features; Skeletal Dysplasia; Congenital Abnormality; Microcephaly; Macrocephaly
    • NCT00001639
      Completed
      Evaluation of Patients With Unresolved Chromosome Abnormalities
      Conditions: Abnormalities; Failure to Thrive; Mental Retardation; Microcephaly
    • NCT04463316
      Recruiting
      GROWing Up With Rare GENEtic Syndromes
      Conditions: Prader-Willi Syndrome; PWS-like Syndrome; Silver Russel Syndrome; Congenital Hypopituitarism; Klinefelter (XXY-)Syndrome; Congenital Adrenal Hyperplasia; XXXXY Syndrome; XXYY Syndrome; XXXX Syndrome (Tetra-X Syndrome); Disorders of Sex Development; Turner Syndrome; 46, XY DSD; Tuberous Sclerosis; Neurofibromatosis; Albright Hereditaire Osteodystrofie; Cornelia de Lange Syndrome; Saethre-Chotzen Syndrome; 17p- Deletiesyndrome; VCF Syndrome; POLR3A Mutatie; Ohdo Syndrome; Jacobsen Syndrome / 11 q Syndrome; Myrhe Syndrome; CHARGE Syndrome; 1q25-32 Deletie; Bardet Biedl Syndrome; Rett Syndrome; 22q11 Deletion Syndrome; Allan-Herndon-Dudley Syndrome; Kallmann Syndrome; Rare Bone Disorders; Noonan Syndrome; Williams-Beuren Syndrome
    • NCT01151462
      Withdrawn
      Postnatal HCMV Infection in Very Preterm Infants. Implications, Morbidity, Growth and Neurodevelopmental Outcomes.
      Conditions: Hearing Loss; Mental Retardation; Microcephaly; Chorioretinitis
    • NCT03922594
      Recruiting
      Surveillance of Zika-related Microcephaly in Sub-Saharan Africa and Asia
      Conditions: Microcephaly; Congenital Infection
    • NCT03651687
      Recruiting
      Guangzhou Surveillance and Clinical Study in Microcephaly (GSCSM)
      Conditions: Microcephaly
    • NCT02943304
      Unknown status
      Neurodevelopment Outcome of Newborns Exposed to Zika Virus (ZIKV) in Utero
      Conditions: Microcephaly; Mental Retardation
    • NCT04569149
      Recruiting
      Primordial Dwarfism Registry
      Conditions: MOPDII; MOPDI; MOPDIII; Taybi Linder Syndrome; Meier-Gorlin Syndrome; Saul-Wilson Syndrome; Ligase 4 Syndrome; Lowry Wood Syndrome; Microcephalic Primordial Dwarfism
    • NCT04656171
      Not yet recruiting
      Microcephaly, Fanconi Anemia and Praxial Disorders
      Conditions: Fanconi Anemia
    • NCT04595513
      Recruiting
      Stopping TSC Onset and Progression 2: Epilepsy Prevention in TSC Infants
      Conditions: Tuberous Sclerosis Complex; Epilepsy
    • NCT04485104
      Recruiting
      Safety, Pharmacokinetics, and Exploratory Efficacy Assessment of Adjunctive Cannabidiol Oral Solution (GWP42003-P) Compared With Standard of Care Antiepileptic Therapy, in Patients Age 1 Month to <12 Months of Age With Tuberous Sclerosis Complex Who Experience Inadequately-controlled Seizures
      Conditions: Seizure in Participants With Tuberous Sclerosis Complex
    • NCT04285346
      Recruiting
      Adjunctive Ganaxolone Treatment (Part A) in TSC Followed by Long-term Treatment (Part B)
      Conditions: Tuberous Sclerosis
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