Clinical Trials on Malignant Astrocytoma

Total 5954 results

Duke University
Genentech, Inc.

Completed

Bevacizumab Beyond Progression (BBP) (BBP)

Glioblastoma | Malignant Glioma | Gliosarcoma | Grade 4 Malignant Glioma

United States
Sun Yat-sen University

Terminated

Treatment Strategy for Low-grade Gliomas

Oligoastrocytoma | Astrocytomas | Oligodendrogliomas

China
Novelwise Pharmaceutical Corporation

Recruiting

NBM-BMX Administered Orally to Patients With Solid Tumors or Newly Diagnosed Glioblastoma

Malignant Neoplasm | Malignant Neoplasm of Brain

Taiwan
National Cancer Institute (NCI)

Terminated

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV Melanoma

Recurrent Melanoma | Stage IV Melanoma | Acral Lentiginous Malignant Melanoma | Lentigo Maligna Malignant Melanoma | Nodular Malignant Melanoma | Solar Radiation-related Skin Melanoma | Superficial Spreading Malignant Melanoma

United States
University of Florida
National Cancer Institute (NCI)

Completed

Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme (ATTAC-II)

Glioblastoma | Glioblastoma Multiforme | Malignant Glioma | GBM | Astrocytoma, Grade IV

United States
Oblato, Inc.

Active, not recruiting

Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma

Recurrent Malignant Glioma | Brain Glioblastoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Mind-Body Intervention in Glioma Couples

Glioblastoma | Malignant Glioma | WHO Grade III Glioma | Metastatic Malignant Neoplasm in the Brain | Low Grade Glioma | Partner

United States
National Cancer Institute (NCI)

Completed

AZD8055 for Adults With Recurrent Gliomas

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Brainstem Glioma

United States
INSYS Therapeutics Inc

Completed

Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Mixed Oligoastrocytoma

United States
Fondazione Policlinico Universitario Agostino Gemelli...
Catholic University of the Sacred Heart; Heinrich-Heine University, Duesseldorf and other collaborators

Recruiting

Grafts of GSCs Into Brain Organoids for Testing Anti-invasion Drugs (2253)

Glioblastoma | Glioma, Malignant

Italy
Sanofi

Completed

Study of the Poly (ADP-ribose) Polymerase-1 (PARP-1) Inhibitor BSI-201 in Patients With Newly Diagnosed Malignant Glioma

Glioblastoma

United States
Fondazione Policlinico Universitario Agostino Gemelli...
Istituto Superiore di Sanità; Fondazione C.N.R./Regione Toscana "G. Monasterio...

Recruiting

Modulation of Ciliogenesis in Glioma Stem Cells (RF2019-1236878)

Glioblastoma | Glioma, Malignant

Italy
Duke University

Not yet recruiting

Bispecific T Cell Engager BRiTE for Patients With Grade IV Malignant Glioma (BRiTE)

Glioblastoma | Malignant Glioma

United States
Michael Gunn
National Cancer Institute (NCI)

Withdrawn

Monocyte Antigen Carrier Cells for Newly Diagnosed GBM (DEMAND)

Glioblastoma | Glioma, Malignant

United States
Duke University
Personalis Inc.

Recruiting

GRETeL: Tumor Response to Standard Radiotherapy and TMZ Patients With GBM

Glioblastoma | Glioma, Malignant

United States
InSightec

Recruiting

Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption in GBM Patients

Glioblastoma | Glioma, Malignant

Italy, Spain
Zentrum fur Humangenetik Tuebingen

Available

Glioblastoma and Individualized Therapies

Glioma, Malignant

Germany
Mayo Clinic
National Cancer Institute (NCI)

Completed

18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy

Glioblastoma | Malignant Glioma

United States
Pfizer

Terminated

First in Patient Study for PF-06840003 in Malignant Gliomas

Astrocytoma | Malignant Glioma | Oligodendroglioma

United States
Duke University

Terminated

Procedural Outcomes in Endobronchial Ultrasound - Transbronchial Needle Aspiration (EBUS-TBNA) With and Without Rapid On-Site Evaluation (ROSE) (ROSE)

ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION | Benign and Malignant Mediastinal and Hilar Lymph Nodes Known or Suspected Malignancy

United States
Fred Hutchinson Cancer Center

Terminated

O6-Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cell in Treating Patients With Malignant Gliomas

Glioblastoma | Gliosarcoma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Treovir, LLC; American Lebanese Syrian Associated...

Not yet recruiting

HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma

Neoplasms | Malignant Glioma of Brain | Glioblastoma Multiforme | High Grade Glioma | Giant Cell Glioblastoma | High-grade Glioma | Anaplastic Astrocytoma of Brain | Anaplastic Glioma

United States
Tactical Therapeutics, Inc.

Active, not recruiting

Safety and Tolerability of Carboxyamidotriazole Orotate (CTO) in Solid Tumors or With Temodar® in Glioblastoma or Other Recurrent Malignant Gliomas or in Combination With Temodar® and Radiation Therapy for Patients With Newly Diagnosed Glioblastoma and Malignant Gliomas

Solid Tumors, Glioblastoma, Recurrent Malignant Gliomas

United States
Indiana University

Terminated

Pilot Study of Cabozantinib for Recurrent or Progressive Central Nervous System Tumors in Children

Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Malignant Brain Tumor

United States
Thomas Jefferson University

Recruiting

Analysis of Cell Count, Viability, and Immunogenicity of Discarded Newly Diagnosed Glioblastoma Tissue or Solid Tumor Tissues

Malignant Solid Neoplasm | Glioblastoma

United States
Duke University
GlaxoSmithKline; Genentech, Inc.

Completed

Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma

Glioblastoma | Malignant Glioma | Gliosarcoma

United States
Celldex Therapeutics

Completed

Phase II Study of Rindopepimut (CDX-110) in Patients With Glioblastoma Multiforme (ACT III)

Malignant Glioma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent WHO Grade III Glioma | Recurrent Gliosarcoma | Recurrent Anaplastic Astrocytoma | Recurrent Anaplastic Oligoastrocytoma | Recurrent Anaplastic Oligodendroglioma

United States
National Cancer Institute (NCI)

Completed

VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Terminated

RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Patients With Recurrent or Progressive Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
University of Michigan Rogel Cancer Center
Phase One Foundation

Completed

Combined Cytotoxic and Immune-Stimulatory Therapy for Glioma

Glioblastoma Multiforme | Malignant Glioma

United States
AbbVie

Completed

Study Evaluating ABT-414 in Japanese Subjects With Malignant Glioma

Glioblastoma Multiforme | Malignant Glioma

Japan
Hopital Foch
National Cancer Institute, France

Not yet recruiting

Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide (OPTIMUM)

Glioblastoma, IDH-wildtype

France, Italy
University of Cincinnati

Active, not recruiting

Feasibility Study of Modified Atkins Ketogenic Diet in the Treatment of Newly Diagnosed Malignant Glioma

Glioblastoma

United States
Taichung Veterans General Hospital

Unknown

Simultaneous Integrated Boost in Malignant Glioma Patients Treated With Chemoradiation

Chemoradiation | Glioblastoma Multiforme

Taiwan
Duke University
Genentech, Inc.; Eisai Inc.

Terminated

A Study of Gliadel Followed by Avastin + Irinotecan for Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme | Malignant Glioma | Gliosarcoma

United States
Burzynski Research Institute

Completed

Antineoplaston Therapy in Treating Children With Low-Grade Astrocytoma

Low Grade Astrocytomas

United States
Duke University
Pfizer

Completed

Ph. II Treatment of Adults w Primary Malignant Glioma w Irinotecan + Temozolomide

Glioblastoma

United States
Henry Ford Health System

Recruiting

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

Glioma | Glioblastoma | Astrocytoma | Malignant Glioma of Brain | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | GBM | Malignant Astrocytoma

United States
St. Jude Children's Research Hospital

Recruiting

Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma

Glioma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Pilocytic Astrocytoma | Optic Pathway Glioma | Pilomyxoid Astrocytoma

United States
Celgene
Triphase

Completed

Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumab

Glioblastoma | Malignant Glioma

United States, Canada
Celgene
Triphase

Completed

Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancer

Glioblastoma | Malignant Glioma

United States, Canada, Switzerland
National Cancer Institute (NCI)

Completed

Sunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or Ependymoma

Recurrent Childhood Ependymoma | Childhood Infratentorial Ependymoma | Childhood Supratentorial Ependymoma | Recurrent Childhood Cerebellar Astrocytoma | Recurrent Childhood Cerebral Astrocytoma | Recurrent Childhood Subependymal Giant Cell Astrocytoma | Childhood Mixed Glioma | Childhood Oligodendroglioma and other conditions

United States, Canada, Australia
NanoPharmaceuticals LLC

Recruiting

Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma

Glioma, Malignant

United States
Duke University

Recruiting

The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluation

Glioblastoma | Malignant Glioma

United States
Rigshospitalet, Denmark
Danish Center for Interventional Research in Radiation Oncology (CIRRO)

Terminated

Image Guided Reirradiation of High-grade Glioma

Glioblastoma | Malignant Glioma

Sweden, Denmark
Nanfang Hospital of Southern Medical University
The First Affiliated Hospital of Nanchang University; Xiangya Hospital of Central... and other collaborators

Unknown

Treatment Response and Prognosis in Glioma Patients: Q Cell and Its Biological Characteristics

Glioblastoma | Malignant Glioma

China
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma

Malignant Neoplasms of Eye, Brain and Other Parts of Central Nervous System

United States
Armando Santoro, MD
GlaxoSmithKline; Istituto Clinico Humanitas

Not yet recruiting

Niraparib and Temozolomide in Patients Glioblastoma (ONC-2022-001)

Glioma, Malignant

Italy

Clinical Trials on Malignant Astrocytoma

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Estonia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations