Clinical Trials on Malignant Lymph Node Neoplasm in South Africa

Total 1619 results

Trans Tasman Radiation Oncology Group
University Medical Center Groningen; Australian and New Zealand Intensive Care...

Completed

Immediate Radiotherapy or Observation After Surgery for Melanoma Involving Lymph Nodes

Lymph Node Disease | Malignant Melanoma

Australia, New Zealand, Netherlands, Brazil
Akesobio Australia Pty Ltd

Completed

A Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK117 as Monotherapy or in Combination With AK104

Neoplasms Malignant

Australia
Hoffmann-La Roche

Completed

An Open-Label Study of Zelboraf (Vemurafenib) in Patients With Braf V600 Mutation Positive Metastatic Melanoma

Malignant Melanoma

South Africa
Nova Laboratories Limited

Completed

Bioequivalence of An Oral Mercaptopurine Suspension 100 Mg / 5 Ml Versus Tablet in Healthy Male Subjects Under Fasting Conditions

Acute Lymphoblastic Leukemia

South Africa
NRG Oncology
National Cancer Institute (NCI)

Active, not recruiting

Testing Whether Treating Breast Cancer Metastases With Surgery or High-Dose Radiation Improves Survival

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Metastatic Malignant Neoplasm in the Lymph Nodes | Metastatic Malignant Neoplasm in the Liver | Metastatic Breast Carcinoma | Metastatic Malignant Neoplasm in the Lung and other conditions

United States, Canada, Saudi Arabia, Korea, Republic of
University of Cape Town

Recruiting

Evaluating Acid Reflux After Oesophageal Stenting Using Anti-reflux Stents

Esophageal Cancer | Reflux, Gastroesophageal

South Africa
National Cancer Institute (NCI)

Unknown

Combination Chemotherapy in Patients With Advanced or Recurrent Mycosis Fungoides

Lymphoma

South Africa
Akesobio Australia Pty Ltd

Recruiting

A Study of AK112, a PD-1/VEGF Bispecific Antibody, for Advanced Solid Tumors

Neoplasms Malignant

Australia
Hoffmann-La Roche

Completed

A Pharmacokinetics (PK) Study to Investigate the Effect of Rifampin on PK of Vemurafenib (Zelboraf)

Malignant Melanoma, Neoplasms

United States, South Africa, Croatia, Brazil, Egypt
Johns Hopkins University
United States Agency for International Development (USAID)

Not yet recruiting

Shortened Regimen for Drug-susceptible TB in Children (SMILE-TB)

Tuberculosis | Tuberculosis, Pulmonary | Mycobacterium Tuberculosis | Tuberculosis, Lymph Node

Uganda, South Africa, Mozambique, Indonesia, Zambia
National Cancer Institute (NCI)

Recruiting

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

Malignant Solid Neoplasm

United States
Gary Morrow
National Cancer Institute (NCI)

Completed

Multimedia Psychoeducation or Print Education in Preparing Cancer Patients for Decision Making About Clinical Trials

Malignant Neoplasm

United States
National Cancer Institute (NCI)

Recruiting

Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With AKT Mutations, A ComboMATCH Treatment Trial

Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Puerto Rico
University of Cape Town

Completed

Iron Deficiency Anaemia in Pregnant Patients Presenting for Antenatal Care

Iron Deficiency Anemia of Pregnancy

South Africa
BioSyngen Pte Ltd

Unknown

A Study of Syngenon (BSG-001) for Inhalation in Subjects With Malignant Pleural Effusion and/or Malignant Ascites

Malignant Ascites | Malignant Pleural Effusion

Australia
University Medical Center Groningen
NRG Oncology; Dutch Cancer Society

Recruiting

Groningen International Study on Sentinel Nodes in Vulvar Cancer-III (GROINSS-VIII)

Vulvar Cancer | Sentinel Lymph Node | Lymph Node Metastases

United States, Netherlands
National Cancer Institute (NCI)

Active, not recruiting

Molecular Profiling in Tissue Samples From Patients With Cancer Who Are Exceptional Responders to Treatment

Malignant Neoplasm

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Does the Use of a Genomic Tumor Board Increase the Number of Patients Who Receive Genome-Informed Treatment

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Puerto Rico
Hoffmann-La Roche

Completed

A Study of Continued Treatment Among Participants Who Have Responded to Peginterferon Alfa-2a (Pegasys®) or Recombinant Interferon Alfa-2a (Roferon-A®) in Prior Clinical Studies

Renal Cell Carcinoma | Chronic Myelogenous Leukemia | Malignant Melanoma

Canada, India, Bulgaria, Russian Federation, Spain, South Africa, Slovakia
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Reproductive Health Program in Patients With Cancer (EROS)

Malignant Neoplasm

United States
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Neuropsychological and Behavioral Testing in Younger Patients With Cancer

Childhood Malignant Neoplasm

United States, Canada, Puerto Rico, Australia, New Zealand
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors

Childhood Malignant Neoplasm

United States, Canada, Australia, Puerto Rico, Switzerland
National Cancer Institute (NCI)

Suspended

Testing the Use of Nilotinib and Paclitaxel as a Treatment for Patients With Prior Taxane Treatment, A ComboMATCH Treatment Trial

Refractory Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Recruiting

Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Metastatic Malignant Neoplasm in the Lymph Nodes | Metastatic Malignant Neoplasm in the Soft Tissues | Metastatic Malignant Neoplasm in the Viscera and other conditions

United States, Puerto Rico
Hoffmann-La Roche

Completed

A Pharmacokinetics Study to Investigate the Effect of Vemurafenib on Digoxin in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma

Malignant Melanoma, Neoplasms

Russian Federation, Korea, Republic of, Israel, South Africa, Belarus
City of Hope Medical Center
Patient-Centered Outcomes Research Institute; National Cancer Institute (NCI)

Active, not recruiting

Home Base Telemonitoring in Gastrointestinal, Genitourinary, or Gynecologic Cancer Patients Undergoing Abdominal Surgery

Malignant Solid Neoplasm | Digestive System Carcinoma | Malignant Female Reproductive System Neoplasm | Genitourinary System Carcinoma

United States
Clover Biopharmaceuticals AUS Pty Ltd

Completed

Study With SCB-313 (Recombinant Human TRAIL-Trimer Fusion Protein) for Treatment of Malignant Pleural Effusions

Malignant Pleural Effusions

Australia
National Cancer Institute (NCI)

Terminated

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV Melanoma

Recurrent Melanoma | Stage IV Melanoma | Acral Lentiginous Malignant Melanoma | Lentigo Maligna Malignant Melanoma | Nodular Malignant Melanoma | Solar Radiation-related Skin Melanoma | Superficial Spreading Malignant Melanoma

United States
BioCryst Pharmaceuticals

Completed

First-in-Human Study of BCX9930 in Healthy Volunteers and Patients With PNH

Paroxysmal Nocturnal Hemoglobinuria

United Kingdom, Austria, South Africa
Brigham and Women's Hospital
Harvard Medical School (HMS and HSDM); Massachusetts General Hospital; Columbia... and other collaborators

Active, not recruiting

Standing Tall (Yima Nkqo)

HIV

United States, South Africa
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Financial Navigation Program to Improve Understanding and Management of Financial Aspects of Cancer Care for Patients and Their Spouses (CREDIT)

Hematopoietic and Lymphoid Cell Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Puerto Rico
BioCryst Pharmaceuticals

Recruiting

Dose Escalation of BCX10013 in Subjects With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

South Africa, Malaysia
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Vincristine Pharmacokinetics in Infants

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States, Australia, Canada
Wales Cancer Trials Unit
Velindre NHS Trust; June Hancock Mesothelioma Research Fund; Velindre Cancer...

Unknown

A Phase II Trial to Assess TroVax® Plus Chemotherapy in Patients With Malignant Pleural Mesothelioma (SKOPOS)

Mesothelioma | Malignant | Pleural

United Kingdom
Exact Sciences Corporation

Terminated

Blood Sample Collection to Evaluate Biomarkers in Subjects With Untreated Hematologic Malignancies

Hematologic Malignancy

United States
Clarity Pharmaceuticals Ltd

Completed

64Cu-SAR-bisPSMA for Identification of Participants With Recurrence of Prostate Cancer (COBRA) (COBRA)

Biochemical Recurrence of Malignant Neoplasm of Prostate

United States
Millennium Pharmaceuticals, Inc.

Terminated

A Dose Escalation Study of MLN7243 (TAK-243) in Adult Participants With Advanced Solid Tumors

Advanced Malignant Solid Tumors

United States
The Netherlands Cancer Institute
Bristol-Myers Squibb

Active, not recruiting

Optimal Neo-adjuvant Combination Scheme of Ipilimumab and Nivolumab (OpACIN-neo)

Malignant Melanoma Stage III

Austria, Netherlands, Australia, Sweden
Virttu Biologics Limited

Completed

Intrapleural Administration of HSV1716 to Treat Patients With Malignant Pleural Mesothelioma. (1716-12)

Malignant Pleural Mesothelioma

United Kingdom
Agendia

Completed

PRospective Study Of MammaPrint in Patients With an Intermediate Recurrence Score (PROMIS)

Hormone Receptor Positive Malignant Neoplasm of Breast

United States
Children's Oncology Group
National Cancer Institute (NCI); MedStar Georgetown University Hospital

Active, not recruiting

Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States, Canada
International Atomic Energy Agency

Completed

Palliative Radiotherapy and Brachytherapy for Oesophageal Cancer Dysphagia

Esophageal Cancer

China, Canada, Croatia, India, Pakistan, South Africa, Thailand
Clarity Pharmaceuticals Ltd

Active, not recruiting

64Cu-SAR-BBN for Identification of Participants With Recurrence of Prostate Cancer (SABRE) (SABRE)

Biochemical Recurrence of Malignant Neoplasm of Prostate

United States
BioCryst Pharmaceuticals

Terminated

A Long Term Safety Study of BCX9930 in Subjects With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria | PNH

United Kingdom, Austria, South Africa
Akeso

Not yet recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK114

Metastasis | Advanced or Metastatic Solid Tumors | Malignancy

Australia
Piramal Enterprises Limited
Melanoma Research Foundation Breakthrough Consortium

Suspended

Study of an Oral Cdk Inhibitor Administered With an Oral BRAF Inhibitor in Patients With Advanced or Inoperable Malignant Melanoma With BRAF Mutation

Advanced or Inoperable Malignant Melanoma With BRAF Mutation

United States
Asbestos Diseases Research Foundation
EnGeneIC Limited

Completed

MesomiR 1: A Phase I Study of TargomiRs as 2nd or 3rd Line Treatment for Patients With Recurrent MPM and NSCLC

Non-Small Cell Lung Cancer | Malignant Pleural Mesothelioma

Australia
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central Nervous System Neoplasm | Childhood Solid Neoplasm

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

Hepatoblastoma | Fibrolamellar Carcinoma | Childhood Hepatocellular Carcinoma | Childhood Malignant Liver Neoplasm | Hepatocellular Malignant Neoplasm, Not Otherwise Specified

United States, Canada, Saudi Arabia, Puerto Rico, Australia, New Zealand
Pfizer

Terminated

An Investigational Drug, Crizotinib (PF-02341066), Is Being Studied In Tumors, Except Non-Small Cell Lung Cancer, That Are Positive For Anaplastic Lymphoma Kinase (ALK)

Neoplasms Malignant

United States, Korea, Republic of, Japan, China, Taiwan, Italy, Russian Federation

Clinical Trials on Malignant Lymph Node Neoplasm in South Africa

Sponsors and Collaborators

Medical Conditions

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CROs by country

CROs in Liberia

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Rare Diseases

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