Clinical Trials on Malignant Neoplasms of Eye Brain and Other Parts of Central Nervous System in Japan

Total 253 results

Hokkaido University Hospital

Completed

Prospective Randomized Trial Between WBRT Plus SRS Versus SRS Alone for 1-4 Brain Metastases

Brain Metastasis

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Brexpiprazole for the Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's Type

Agitation Associated With Dementia of the Alzheimer's Type

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Brexpiprazole for the Long-term Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's Type

Agitation Associated With Dementia of the Alzheimer's Type

Japan
Otsuka Pharmaceutical Co., Ltd.

Terminated

Aripiprazole for the Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's Type

Agitation Associated With Dementia of the Alzheimer's Type

Japan
Nihon Pharmaceutical Co., Ltd

Completed

Phase II Clinical Trial of NPB-01 in Patients With Anti-aquaporin 4 Antibody Positive Neuromyelitis Optica Spectrum Disorder Not Provided Adequate Effect of Therapy to Steroids Plus Therapy.

Neuromyelitis Optica Spectrum Disorder

Japan
HeadSense Medical

Suspended

An Evaluation of Non-Invasive ICP Monitoring in Patients Undergoing Invasive ICP Monitoring Via an Intraparenchymal Pressure Monitoring Device

Stroke | Brain Injuries | Brain Neoplasms | Intracranial Hypertension | Hydrocephalus

Japan
Karthick Balasubramanian

Not yet recruiting

tDCS for Neurological Disability Among Subacute Stroke Survivors to Improve Multiple Domains in Quality of Life

Stroke | Stroke, Ischemic

Saudi Arabia
European Organisation for Research and Treatment...
Japan Clinical Oncology Group; European Society of Surgical Oncology

Completed

Diffusion-Weighted MRI for Liver Metastasis (DREAM)

Colorectal Cancer | Colon Cancer Liver Metastasis | Malignant Neoplasm of Rectum Metastatic to Liver

France, Japan, Belgium, United States, Austria
Kyoto Breast Cancer Research Network
Pfizer

Completed

Neoadjuvant Hormonal Therapy Plus Palbociclib in Operable, Hormone Sensitive and HER2-Negative Primary Breast Cancer

Hormone Receptor Positive Malignant Neoplasm of Breast | Breast Cancer Female

Taiwan, Japan, Korea, Republic of, Australia, Hong Kong
University Hospital, Lille

Completed

Pre-stroke Cognitive Status and Thrombolytic Therapy (OPHELIE-COG)

Brain Ischemia | Dementia | Adverse Effect of Thrombolytic Drugs | Impaired Cognition

France, Japan
Nobelpharma

Completed

Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC)

Plaque | Tuberous Sclerosis | Angiofibroma | Hypomelanotic Macule

Japan
Nobelpharma

Completed

Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex

Plaque | Tuberous Sclerosis | Angiofibroma | Hypomelanotic Macule

Japan
Janssen Pharmaceutical K.K.

Completed

Evaluation of Efficacy and Safety of Galantamine in Patients With Dementia of Alzheimer's Type Who Failed to Benefit From Donepezil

Alzheimer's Disease

Japan
Benesis Corporation

Completed

Efficacy and Safety Study of GB-0998 for Treatment of Generalized Myasthenia Gravis

Generalized Myasthenia Gravis

Japan
Bayer

Completed

SH L 562BB Phase II/III Dose Justification and Gadoteridol-controlled Comparative Study

Brain Metastases

Japan
Translational Research Center for Medical Innovation...
Department of Nuerosurgery, Osaka Medical College

Completed

Boron Neutron Capture Therapy, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

Japan
Takeda

Completed

Copaxone Subcutaneous Injection Syringe Special Drug Use-Result Investigation (All-Case Investigation) "Prevention of Relapse of Multiple Sclerosis"

Multiple Sclerosis

Japan
Nagano Children's Hospital

Completed

Summary of Infants Weighing 500 Grams or Less

Microcephaly | Infant, Extremely Low Birth Weight

Japan
Sumitomo Pharma Co., Ltd.

Completed

A Study of DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade Gliomas

Glioblastoma | Diffuse Intrinsic Pontine Glioma

Japan
Bayer

Completed

Magnevist (SH L 451A) Intra-individual Dose Comparison Study in Patients With Brain Metastasis

Brain Neoplasms

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Cilostazol Stroke Prevention Study : A Placebo-controlled Double-blind Trial for Secondary Prevention of Cerebral Infarction. (CSPS)

Cerebral Infarction

Japan
Nobelpharma

Active, not recruiting

Clinical Study of NPC-12Y Gel in Patients With Skin Lesions Associated With TSC

Tuberous Sclerosis Complex

Japan
Nihon Pharmaceutical Co., Ltd

Completed

Phase III Clinical Trial of NPB-01 in Patients With Guillain-Barré Syndrome

Guillain-Barré Syndrome

Japan
National Center of Neurology and Psychiatry, Japan

Completed

Phase II Clinical Trial of OCH-NCNP1

Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive

Japan
Hoffmann-La Roche
Chugai Pharmaceutical Co.

Terminated

A Study In Neuromyelitis Optica Spectrum Disorder (NMOSD) With Satralizumab As An Intervention (SAkuraBonsai)

Neuromyelitis Optica Spectrum Disorder | NMOSD

United States, Korea, Republic of, Italy, Canada, Japan, Turkey
Otsuka Pharmaceutical Co., Ltd.

Completed

A Multicenter Trial to Investigate the Efficacy and Safety of Tolvaptan in Patients With Hyponatremia in SIADH

Syndrome of Inappropriate Antidiuretic Hormone Secretion

Japan
Eisai Inc.

Completed

A Post-marketing Observational Study on Risk Factors for Hepatic Encephalopathy in Participants With Unresectable Hepatocellular Carcinoma

Carcinoma, Hepatocellular

Japan
UCB Japan Co. Ltd.
Parexel

Completed

Open-label Study to Evaluate the Safety and Tolerability of iv Lacosamide in Japanese Adults With Partial-onset Seizures

Epilepsy | Partial-onset Seizures

Japan
Japan Blood Products Organization

Completed

Efficacy and Safety Study of GB-0998 for Guillain-Barré Syndrome

Guillain-Barré Syndrome

Japan
Astellas Pharma Inc

Completed

An Open Study for Steroid Resistant, Non-Thymectomized MG Patients

Myasthenia Gravis

Japan
Translational Research Center for Medical Innovation...
Ministry of Health, Labour and Welfare, Japan; Hiroshima University

Completed

Japan Statin Treatment Against Recurrent Stroke (J-STARS)

Ischemic Stroke

Japan
Takeda

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TAK-925 in Healthy Volunteers and Participants With Narcolepsy

Healthy Participants | Narcolepsy

Japan
Eisai Co., Ltd.

Completed

Investigation of the Clinical Safety and Efficacy of Long-term Treatment With Fycompa Tablets in Adolescence Epilepsy Patients With Partial-onset Seizures (With or Without Secondary Generalized Seizures) or Primary Generalized Tonic-clonic Seizures (FYC02T)

Partial Seizures (With or Without Secondary Generalized Seizures) | Primary Generalized Tonic-clonic Seizures

Japan
Novo Nordisk A/S

Completed

Non-interventional Study of Patients Using Norditropin® for Growth Hormone Deficiency or Turner Syndrome (NordiPAD)

Turner Syndrome | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder

Japan
Eisai Co., Ltd.

Completed

Investigation of the Clinical Safety and Efficacy of Long-term Treatment With Fycompa Tablets in Adult Epilepsy Patients With Partial-onset Seizures (With or Without Secondary Generalized Seizures) or Primary Generalized Tonic-clonic Seizures (FYC01S)

Partial Seizures (With or Without Secondary Generalized Seizures) | Primary Generalized Tonic-clonic Seizures

Japan
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., Japan

Completed

SJ-0021 (Gonalef®) Versus Purified Pituitary Gonadotropin (Fertinorm-P®) for Ovulation Induction in Japanese Infertile Women

Infertility | Ovulation Induction

Japan
Takeda

Completed

Phase 1 TAK-925 Study in Healthy Adult and Elderly Volunteers and Participants With Narcolepsy

Healthy Participants and Patients With Narcolepsy

Japan
Kochi University

Completed

Preoperative Oral Supplementation With Branched-Chain Amino Acids (BCAA) Improves Postoperative Quality of Life (KMS)

Hepatocellular Carcinoma | Chronic Liver Disease

Japan
Kyowa Kirin Co., Ltd.

Completed

A Drug Interaction Study of KW-6356 With Midazolam, Caffeine, or Rosuvastatin

Parkinson's Disease

Japan
Kyowa Kirin Co., Ltd.

Completed

A Study of Single and Multiple Doses of KW-6356 in Healthy Subjects

Parkinson's Disease

Japan
Kyowa Kirin Co., Ltd.

Completed

Long-Term Safety Study of KW-6500 in Patients With Parkinson's Disease

Parkinson's Disease

Japan
Takeda

Completed

Rasagiline Tablets Special Drug Use-Results Survey "Survey on Long-term Safety"

Parkinson's Disease

Japan
H. Lundbeck A/S

Completed

A Trial Investigating Lu AF28996 in Adult Japanese Participants With Parkinson's Disease (PD)

Parkinson Disease

Japan
Kyowa Kirin Co., Ltd.

Completed

A Study of Istradefylline (KW-6002) for the Treatment of Parkinson's Disease in Patients Taking Levodopa

Parkinson's Disease

Japan
Kyowa Kirin Co., Ltd.

Completed

A Phase 2b Study of Istradefylline (KW-6002) for the Treatment of Parkinson's Disease in Patients Taking Levodopa

Parkinson's Disease

Japan
Kyowa Kirin Co., Ltd.

Completed

Study of KW-6002 (Istradefylline) for the Treatment of Parkinson's Disease in Patients Taking Levodopa (6002-009)

Parkinson's Disease

Japan
UCB Japan Co. Ltd.

Completed

A Trial to Evaluate the Long Term Safety and Tolerability of Lacosamide Taken as Monotherapy in Adults With Partial-onset Seizures

Epilepsy | Partial-onset Seizures

Japan
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

A Trial of Postoperative Whole Brain Radiation Therapy vs. Salvage Stereotactic Radiosurgery Therapy for Metastasis

Neoplasm Metastasis | Brain Neoplasms

Japan
Kyowa Kirin Co., Ltd.

Completed

Long-Term Safety Study of KW-6002 (Istradefylline) in Parkinson's Disease Patients (6002-010)

Parkinson's Disease

Japan
Kyowa Kirin Co., Ltd.

Completed

A Study of Istradefylline (KW-6002) for the Treatment of Parkinson's Disease

Parkinson's Disease

Japan

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