Clinical Trials on Malignant Disease

Total 381311 results

Li Yu

Unknown

Clinical Study of DC-CIK Cells as a Post-remission Treatment for Malignant Tumors

Malignant Neoplasm

China
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Early Oral Supplementation in Improving Nutritional Status in Patients Undergoing Hematopoietic Stem Cell Transplant

Malignant Neoplasm

United States
Medical University of Vienna

Unknown

EXtendedAnalysis for Cancer Treatment

Malignant Solid Tumor

Austria
Sanofi
Merck KGaA, Darmstadt, Germany

Completed

A Safety and Efficacy Study of SAR405838 and Pimasertib in Cancer Patients

Neoplasm Malignant

Netherlands, France
Sanofi

Completed

Phase I, Dose Escalation of SAR125844 in Asian Solid Tumor Patients (SARMETA)

Neoplasm Malignant

Korea, Republic of, Japan
Yonsei University

Completed

A Prospective Randomized Study for Efficacy of Uncovered Double Bare Metallic Stent Compared to Uncovered Single Bare Metallic Stent in Malignant Biliary Obstruction

Malignant Biliary Obstruction

Korea, Republic of
Sanofi
Regeneron Pharmaceuticals

Completed

A Phase I Study of Aflibercept Plus FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin) in Chinese Patients With Advanced Solid Malignancies

Neoplasm Malignant

China
Sanofi

Completed

Effect of SAR302503 on ECG Activity in Patients With Solid Tumors

Neoplasm Malignant

Belgium, United States
Sanofi
Regeneron Pharmaceuticals

Completed

A Study of Intravenous Aflibercept With Docetaxel in Chinese Patients With Solid Tumors

Neoplasm Malignant

China
Sanofi

Completed

Effect of Cabazitaxel on the QTc Interval in Cancer Patients (QT-Cab)

Neoplasms, Malignant

United States, Belgium, Denmark, Netherlands, Sweden
Ethicon Endo-Surgery

Completed

Harmonic ACE®+7 Shears in Laparoscopic Colectomy

Benign or Malignant Disease Indicated for Colectomy

United States, Belgium, United Kingdom
Singapore General Hospital

Completed

A Prospective, Randomized Controlled Trial for a Rapid Pleurodesis Protocol for the Management of Pleural Effusions

Malignant Pleural Effusions

Singapore
Eastern Regional Medical Center

Recruiting

Combination Tissue Plasminogen Activator (Tpa) and Dornase Alfa (Dnase) Administration Through Intrapleural Catheters for the Treatment of Loculated or Non-Draining Malignant Pleural Effusions

Loculated or Non-draining Malignant Pleural Effusions

United States
Hutchison Medipharma Limited

Recruiting

HMPL-453 in Advanced Malignant Mesothelioma

Advanced Malignant Mesothelioma

China
Vanderbilt-Ingram Cancer Center
National Institute of Nursing Research (NINR); Palliative Care Research Cooperative...

Completed

PCRC-Supported Legacy Intervention in Pediatric Palliative Care

Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | Care Giver

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Recruiting

Palliative Radiation Therapy in Reducing Pain in Patients With Bone Metastasis

Pain | Metastatic Malignant Neoplasm in the Bone | Malignant Neoplasm

United States
National Cancer Institute (NCI)

Completed

PXD101 as Second-Line Therapy in Treating Patients With Malignant Mesothelioma of the Chest That Cannot Be Removed By Surgery

Recurrent Malignant Mesothelioma | Advanced Malignant Mesothelioma | Epithelial Mesothelioma | Sarcomatous Mesothelioma

United States
National Cancer Institute (NCI)

Completed

S0509 - AZD2171 in Treating Patients With Malignant Pleural Mesothelioma That Cannot Be Removed By Surgery

Recurrent Malignant Mesothelioma | Advanced Malignant Mesothelioma | Epithelial Mesothelioma | Sarcomatous Mesothelioma

United States
National Cancer Institute (NCI)

Completed

Gefitinib in Treating Patients With Malignant Mesothelioma

Recurrent Malignant Mesothelioma | Advanced Malignant Mesothelioma | Epithelial Mesothelioma | Sarcomatous Mesothelioma

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Brain

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

EHealth Mindful Movement and Breathing in Improving Outcomes in Participants Undergoing Gynecologic Surgery

Ovarian Carcinoma | Malignant Uterine Neoplasm | Malignant Female Reproductive System Neoplasm | Ovarian Neoplasm | Uterine Neoplasm | Female Reproductive System Neoplasm | Suspicious for Malignancy

United States
Henan Cancer Hospital

Not yet recruiting

Application of LARS Ligament in Bone Prosthesis Replacement

Malignant Tumor

China
University of Houston

Not yet recruiting

Cancer Survivors Acute Exercise Response 1

Neoplasms Malignant
National Cancer Institute, Naples

Active, not recruiting

"Principle Test" for Isolation and Characterization of Circulating Cancer Cells (CTC)-CXCR4+.

Neoplasm Malignant

Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Survey of Post-Acute Inpatient Rehabilitation Safety Concerns in Participants With Cancer

Malignant Neoplasm

United States
Jiangsu Simcere Pharmaceutical Co., Ltd.

Completed

Endostar and/or Cisplatin for Treatment of Malignant Pleural Effusion or Ascites

Malignant Ascites | Malignant Pleural Effusion

China
China Meitan General Hospital
Marino Biotechnology Co., Ltd.

Unknown

Chimeric Switch Receptor Modified T Cells for Patients With PD-L1+ Recurrent or Metastatic Malignant Tumors

Recurrent PD-L1+ Malignant Tumors | Metastatic PD-L1+ Malignant Tumors

China
Grupo Español Multidisciplinar de Melanoma
GlaxoSmithKline

Completed

Retrospective Analysis of Dabrafenib +/- Trametinib Compassionate Use Experience in Spain (DEIS)

Malignant Melanoma Stage IV | Malignant Melanoma Stage IIIc

Spain
Henan Cancer Hospital

Not yet recruiting

Application of Douyin in Perioperative Period of Malignant Tumor Patients

Perioperative Period | Malignant Tumor of Bone
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Neratinib and Everolimus, Palbociclib, or Trametinib in Treating Participants With Refractory and Advanced or Metastatic Solid Tumors With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | KRAS Gene Mutation | Metastatic Malignant Solid Neoplasm | EGFR Gene Mutation | ERBB2 Gene Amplification | ERBB2 Gene Mutation | EGFR Gene Amplification | ERBB3 Gene Mutation | ERBB4 Gene Mutation

United States
Sinocelltech Ltd.

Not yet recruiting

Aims to Explore the Safety, Tolerability, and Preliminary Efficacy of SCTB14 in Adult Patients With Advanced Malignant Solid Tumours.

Advanced Malignant Solid Tumours
Mabwell (Shanghai) Bioscience Co., Ltd.

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetic Properties and Preliminary Efficacy of 9MW3811 in Patients With Advanced Solid Tumors

Advanced Malignant Solid Tumor

China
Daiichi Sankyo Co., Ltd.

Completed

Phase 1 Study of DS-6051b in Japanese Subjects With Advanced Solid Malignant Tumors

Advanced Solid Malignant Tumors

Japan
Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Active, not recruiting

Clinical Study of a Personalized Neoantigen Cancer Vaccine in Treating Patients With Advanced Malignant Tumor

Advanced Malignant Solid Tumor

China
University of Cincinnati

Completed

Chloroquine in Combination With Carboplatin/Gemcitabine in Advanced Solid Tumors

Solid Tumors | Malignant Neoplasm

United States
Daiichi Sankyo Co., Ltd.

Completed

Study of DS-1123a in Advanced Solid Tumours

Advanced Solid Malignant Tumors

Japan
Puma Biotechnology, Inc.

Completed

Study Evaluating Safety And Tolerability, Solid Tumor

Advanced Malignant Solid Tumors

Japan
Puma Biotechnology, Inc.

Completed

Study Evaluating Neratinib In Combination With Temsirolimus In Subjects With Solid Tumors

Neoplasms | Malignant Carcinoma

United States, France
Puma Biotechnology, Inc.

Completed

Study Evaluating Neratinib In Combination With Vinorelbine In Subjects With Advanced Or Metastatic Solid Tumors

Advanced Malignant Solid Tumors

Japan
Daiichi Sankyo Co., Ltd.

Terminated

Open Label Study of DS-5573a

Advanced Solid Malignant Tumors

Japan
Seattle Children's Hospital

Suspended

Radiofrequency Ablation (RFA) Of Tumors Acquired In Childhood

Neoplasms, Benign | Neoplasms, Malignant

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care

Delirium | Metastatic Malignant Neoplasm | Recurrent Malignant Neoplasm | Locally Advanced Malignant Neoplasm

United States, Brazil
M.D. Anderson Cancer Center

Terminated

Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for Pleurodesis

Advanced Cancers | Malignant Pleural Effusions

United States
Mayo Clinic

Recruiting

Virtual Mindfulness and Weight Management to Mitigate Risk of Relapse and Improve Wellbeing in Cancer Survivors

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm | Obesity-Related Malignant Neoplasm

United States
NRG Oncology
National Cancer Institute (NCI)

Active, not recruiting

Testing Whether Treating Breast Cancer Metastases With Surgery or High-Dose Radiation Improves Survival

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Metastatic Malignant Neoplasm in the Lymph Nodes | Metastatic Malignant Neoplasm in the Liver | Metastatic Breast Carcinoma | Metastatic Malignant Neoplasm in the Lung and other conditions

United States, Canada, Saudi Arabia, Korea, Republic of
Genmab
BioNTech SE

Recruiting

Trial to Assess the Safety and Preliminary Efficacy of GEN1055 on Malignant Solid Tumors as Monotherapy and as Combination Therapy

Malignant Solid Tumor

Spain
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Phase I Clinical Study of HRS-7058 in Patients With Advanced Malignant Tumour

Advanced Malignant Tumour
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

TQB2928 Injection Combined With Penpulimab in Treatment of Advanced Malignant Tumors.

Advanced Malignant Neoplasm

China
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

Phase I Clinical Study of SHR-5495 in the Treatment of Patients With Advanced Malignant Tumors

Advanced Malignant Tumor

China
Shanghai Junshi Bioscience Co., Ltd.
Sponsor GmbH

Not yet recruiting

The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of JS207 in Patients With Advanced Malignant Tumor

Advanced Malignant Tumor

China

Clinical Trials on Malignant Disease

Sponsors and Collaborators

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Drug Interventions

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Drug Interventions

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