Clinical Trials on Malignant Gastrointestinal Stromal Tumor

Total 3109 results

First Affiliated Hospital of Zhejiang University
Zhejiang Cancer Hospital; Second Affiliated Hospital, School of Medicine, Zhejiang... and other collaborators

Recruiting

Prospective Multicenter Clinical Study of Neoadjuvant Imatinib Mesylate for Gastrointestinal Stromal Tumors (ZJGIST-01)

Gastrointestinal Stromal Tumor | Progression-free Survival | Neoadjuvant

China
National Cancer Institute (NCI)

Completed

Dasatinib and Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumors or Other Sarcomas That Cannot Be Removed by Surgery or Are Metastatic

Gastrointestinal Stromal Tumor | Stage III Soft Tissue Sarcoma | Stage IV Soft Tissue Sarcoma

United States
Northwestern University

Completed

Prospective Trial of EUS-FNA Versus EUS-FNB Using a Novel Core Biopsy Needle (MUCIN)

Pancreatic Cancer | Lymphadenopathy | Gastrointestinal Stromal Tumor

United States
Institut Bergonié

Completed

Efficacy and Safety of PD-0332991 in Advanced Gastrointestinal Stromal Tumors Refractory to Imatinib and Sunitinib (CYCLIGIST)

Advanced Gastrointestinal Stromal Tumors

France
Asan Medical Center

Completed

Phase II Study of Regorafenib Continuous Dosing of Regorafenib in Patients With GISTs

Gastrointestinal Stromal Tumors (GISTs)

Korea, Republic of
Novartis Pharmaceuticals

Completed

Phase II Study Aiming to Evaluate the Efficacy and Safety of Nilotinib Patients With Gastrointestinal Stromal Tumors (GIST) Resistant or Intolerant to Imatinib and or to 2nd Line Tyrosine Kinas (TK) Inhibitor

Gastrointestinal Stromal Tumors (GIST)

Israel
Blueprint Medicines Corporation

Completed

(NAVIGATOR) Study of BLU-285 in Patients With Gastrointestinal Stromal Tumors (GIST) and Other Relapsed and Refractory Solid Tumors

Gastrointestinal Stromal Tumors (GIST) | Other Relapsed or Refractory Solid Tumors

United States, United Kingdom, France, Korea, Republic of, Belgium, Germany, Italy, Netherlands, Poland, Spain
Asan Medical Center

Completed

A Study of Intermittent Dosing Schedule of Imatinib in Patients With Tyrosine Kinase Inhibitor Refractory GISTs

Gastrointestinal Stromal Tumors (GISTs)

Korea, Republic of
Novartis Pharmaceuticals

Completed

A Prospective, Multicenter Study on Best Clinical Use of Imatinib in the Advanced Gastrointestinal Stromal Tumors

Advanced Gastrointestinal Stromal Tumors

Italy
Pamela L. Kunz
Genentech, Inc.

Completed

Ph II of Capecitabine, Carboplatin & Bevacizumab for Gastroesophageal Junction & Gastric Carcinoma

Stomach Cancer | Gastrointestinal Stromal Tumor (GIST) | Gastric (Stomach) Cancer | Neoplasm of Cardioesophageal Junction

United States
Centre Leon Berard
Blueprint Medicines Corporation

Active, not recruiting

French Long Term Registry With Longitudinal Follow up of PDGFRA D842V-GIST Patients (AVIATOR2020)

GIST, Malignant | GIST | PDGFR-Alpha D842V

France
University Medical Center Groningen
Dutch Cancer Society

Recruiting

The GALLOP-11 Study

Gastro-intestinal Stromal Tumors

Netherlands
AB Science

Terminated

Masitinib in First Line Treatment of Gastro-Intestinal Stromal Tumor (GIST)

Gastrointestinal Stromal Tumors

United States, France, Lebanon
TG Therapeutics, Inc.
SCRI Development Innovations, LLC

Completed

TGR-1202 Alone and in Combination With Either Nab-paclitaxel + Gemcitabine or With FOLFOX in Patients With Select Relapsed or Refractory Solid Tumors

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Rectal Cancer | Gastrointestinal Stromal Tumor (GIST)

United States
National Cancer Institute (NCI)

Completed

Doxorubicin Hydrochloride and Alvocidib in Treating Patients With Metastatic or Recurrent Sarcoma That Cannot Be Removed By Surgery

Gastrointestinal Stromal Tumor | Recurrent Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma

United States
Elpiscience Biopharma, Ltd.

Completed

A Study of ES102 (OX40 Agonist) in Patients With Advanced Solid Tumors

Neoplasms | Solid Tumors | Malignant Tumor

China
Elpiscience Biopharma, Ltd.

Terminated

A Study of ES101 (PD-L1x4-1BB Bispecific Antibody) in Patients With Advanced Solid Tumors

Neoplasms | Solid Tumors | Malignant Tumor

China
David Bushnell
National Cancer Institute (NCI); National Institutes of Health (NIH); Holden...

Active, not recruiting

Study to Evaluate the Safety of Combining Two Radionuclide Therapies to Treat Mid-gut Neuroendocrine Tumors

Neuroendocrine Tumor Gastrointestinal, Hormone-Secreting | Neuroendocrine Tumor, Malignant

United States
Pfizer

Completed

Safety And Efficacy Study Of Sunitinib Malate In Chinese Patients With Imatinib Resistant Or Intolerant Malignant Gastrointestinal Stromal Tumor (GIST)

Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors

China
Stanford University
National Institutes of Health (NIH)

Recruiting

Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

Stomach Cancer | Esophageal Cancer | Gastrointestinal Stromal Tumor (GIST) | Gastric (Stomach) Cancer | Gastro-Esophageal(GE) Junction Cancer

United States
Astex Pharmaceuticals, Inc.

Completed

Nitrocamptothecin in Treating Patients With Soft Tissue Sarcomas

Sarcoma | Small Intestine Cancer | Gastrointestinal Stromal Tumor

United States
Cogent Biosciences, Inc.

Recruiting

(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors

Metastatic Cancer | Advanced Gastrointestinal Stromal Tumors

United States, Korea, Republic of, Spain, United Kingdom, Australia, France, Italy, Netherlands, Taiwan, Germany, Denmark, Hong Kong, Canada, Sweden, Norway, Mexico, Czechia, Argentina, Hungary, Brazil, Chile, Poland
Sarcoma Alliance for Research through Collaboration
Bristol-Myers Squibb

Completed

Trial of Dasatinib in Advanced Sarcomas

Chondrosarcoma | Chordoma | Hemangiopericytoma | Rhabdomyosarcoma | Sarcoma, Alveolar Soft Part | Epithelioid Sarcoma | Gastrointestinal Stromal Tumor (GIST) | Giant Cell Tumor of Bone | Sarcoma, Ewing's | Malignant Peripheral Nerve Sheath Tumors

United States
Nanfang Hospital of Southern Medical University

Unknown

ESTD vs. VATS for Upper Gastrointestinal Submucosal Tumors

Leiomyoma | Upper Gastrointestinal Submucosal Tumors (SMTs) | Gastrointestinal Stromal Tumors (GISTs)

China
Pfizer

Completed

Registry For Temsirolimus, Sunitinib, And Axitinib Treated Patients With Metastatic Renal Cell Carcinoma (mRCC), Mantle Cell Lymphoma (MCL), And Gastro-Intestinal Stroma Tumor (GIST) [STAR-TOR] (STAR-TOR)

Lymphoma, Mantle-Cell | Carcinoma, Renal Cell, Advanced | Gastrointestinal Stroma Tumors

Germany
National Cancer Institute (NCI)

Recruiting

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

Solid Tumor | Refractory Solid Tumors | Malignant Solid Tumors | Other Neoplasms Solid Tumors | Pediatric Solid Tumor

United States
Dong-A ST Co., Ltd.

Completed

A Clinical Trial to Compare the Pharmacokinetics of Imatinib Mesylate Tablet 400mg (1 Tablet) and Glivec Film-coated Tablet 100mg (4 Tablets)(Phase I)

Chronic Myeloid Leukemia | Gastrointestinal Stromal Tumor

Korea, Republic of
National Cancer Institute (NCI)

Completed

Bevacizumab and PEG-Interferon Alfa-2b in Treating Patients With Metastatic or Unresectable Carcinoid Tumors

Metastatic Gastrointestinal Carcinoid Tumor | Recurrent Gastrointestinal Carcinoid Tumor | Regional Gastrointestinal Carcinoid Tumor

United States
Beihua Kong
Sun Yat-sen University; Huazhong University of Science and Technology; Zhejiang...

Recruiting

TC or BEP in Treating Patients With Ovarian Malignant Sex Cord-Stromal Tumors (SCST-01)

Ovarian Neoplasms | Ovarian Cancer | Ovarian Sex Cord Stromal Tumor

China
National Cancer Institute (NCI)

Completed

Imatinib Mesylate in Treating Patients With Relapsed or Refractory Solid Tumors of Childhood

Lung Metastases | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Gastrointestinal Stromal Tumor | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Childhood Synovial Sarcoma | Childhood Desmoplastic Small Round Cell Tumor

United States
Centre Oscar Lambret
Canceropôle Nord Ouest; Groupement Interrégional de Recherche Clinique et d...

Recruiting

Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote Monitoring (SUR-CAN)

Glioma | Gastrointestinal Stromal Tumors | Neuroendocrine Tumors | Adenocarcinoma, Clear Cell | Carcinoma, Small Cell | Ovarian Germ Cell Tumor | Stage I Testicular Seminoma | Stage I Testicular Nonseminomatous Germ Cell Tumor | Borderline Ovarian Tumor | Sex Cord-Stromal Tumor | Mucinous Adenocarcinoma of... and other conditions

France
Children's Hospitals and Clinics of Minnesota
M.D. Anderson Cancer Center; Massachusetts General Hospital; Washington University... and other collaborators

Recruiting

International Ovarian & Testicular Stromal Tumor Registry (OTST)

Ovarian Small Cell Carcinoma | Testicular Stromal Tumors | Ovarian Sex-cord Stromal Tumor

United States
AstraZeneca

Completed

The Biological Activity of Cediranib (AZD2171) in Gastro-Intestinal Stromal Tumours(GIST).

Gastrointestinal Stromal Tumors | Soft Tissue Sarcomas

United Kingdom
Royal Marsden NHS Foundation Trust
University College London Hospitals; University of Southampton; St George's University... and other collaborators

Completed

Information Needs Around Parenteral nUTrition in Cancer (INPUT)

Neoplasms | Cancer | Tumor | Malignant Neoplasm | End Stage Cancer | Malignancy | Terminal Cancer

United Kingdom
Centre Francois Baclesse
ARCAGY/ GINECO GROUP

Active, not recruiting

Living After a Rare Cancer of the Ovary: Chronic Fatigue, Quality of Life and Late Effects of Chemotherapy (VIVROVAIRE TR)

Germ Cell Tumor | Sex Cord Stromal Tumor | Malignant Non-epithelial Ovarian Tumors

France
Amneal Pharmaceuticals, LLC
Accutest Research Laboratories (I) Pvt. Ltd.

Completed

Comparative Bioequivalence Study in Adult Patients Suffering From Chronic Myeloid Leukemia & Gastrointestinal Stromal Tumor Under Fed Conditions

Chronic Myeloid Leukemia | Gastrointestinal Stromal Tumor

India
GEM Hospital & Research Center

Completed

Laparoscopic Management of Gastrointestinal Stromal Tumor of Stomach

Gastric GIST | Submucosal Tumor of Stomach
Frederic Amant
Kom Op Tegen Kanker; Research Foundation Flanders

Completed

FUlvestrant in Gynecological Cancers That Are Potentially Hormone Sensitive: the FUCHSia Study (FUCHSia)

Endometrial Cancer | Endometrial Stromal Sarcoma | Sex Cord Stromal Tumor | Adenosarcoma of Uterus | Leiomyosarcoma Uterus | Serous Ovarian Tumor

Belgium, Netherlands
Theseus Pharmaceuticals

Terminated

A Study of THE-630 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

Gastrointestinal Diseases | Neoplasms | Neoplasms, Connective and Soft Tissue | Neoplasms by Histologic Type | Gastrointestinal Neoplasms | Neoplasms, Connective Tissue | Digestive System Neoplasm | Digestive System Disease | Gastrointestinal Stromal Tumors (GIST)

United States
Vall d'Hebron Institute of Oncology
Banc de Sang i Teixits

Recruiting

Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid Tumors (NEXTGENTIL-ACT)

Epithelial Tumors, Malignant | Malignant Solid Tumor

Spain
Sebastian Bauer
Hannover Medical School; University Hospital Tuebingen; Universitätsmedizin Mannheim and other collaborators

Unknown

POETIG Trial - POnatinib After rEsisTance to Imatinib in GIST (POETIG)

GIST, Malignant | KIT Gene Mutation | KIT Exon 13 Mutation

Germany
Northwestern University
National Cancer Institute (NCI)

Completed

Endoscopic Placement of Metal Stents in Treating Patients With Cancer- Related Duodenal Obstruction

Quality of Life | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Small Intestine Cancer | Gastrointestinal Stromal Tumor | Extrahepatic Bile Duct Cancer | Constipation, Impaction, and Bowel Obstruction | Gastrointestinal Carcinoid Tumor

United States
National Cancer Institute (NCI)

Completed

Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma

Gastrointestinal Stromal Tumor | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Adult Rhabdomyosarcoma | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal... and other conditions
Aesculap AG
B.Braun Surgical SA

Withdrawn

Gastrointestinal Anastomosis Using MonoPlus® Suture (GASTROMO)

Gastrointestinal Neoplasms | Gastrointestinal Stromal Tumors | Digestive System Neoplasm | Rectum Tumor | Stomach Tumor | Colon Tumor | Small Intestine Tumor

Spain
University of Alberta

Completed

EUS-guided Fine Needle Biopsy With a New Core Histology Needle Versus Conventional Fine Needle Aspiration

Lymphoma | Pancreas Adenocarcinoma | Pancreas Neoplasms | Gastrointestinal Stromal Tumor

Canada
National Cancer Institute (NCI)

Completed

Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery

Stage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Pleomorphic Liposarcoma | Metastatic Undifferentiated Pleomorphic Sarcoma | Metastatic Unresectable Sarcoma | Unresectable Soft Tissue Sarcoma | Metastatic Soft Tissue Sarcoma | Locally Advanced Soft Tissue Sarcoma | Metastatic... and other conditions

United States
University of Pittsburgh

Recruiting

GIST and Memory and Attention Adaptation Training (GIST-MAAT)

CBT | GIST, Malignant

United States
National Cancer Institute (NCI)

Completed

Linsitinib in Treating Patients With Gastrointestinal Stromal Tumors

Chondrosarcoma | Gastrointestinal Stromal Tumor | Paraganglioma | Carney Complex

United States
Radboud University Medical Center

Unknown

Study to the Optimal Duration of Therapy With Oral Angiogenesis Inhibitors

Renal Cell Carcinoma | Gastrointestinal Stromal Tumor

Netherlands
GOG Foundation
National Cancer Institute (NCI)

Active, not recruiting

Paclitaxel and Carboplatin or Bleomycin Sulfate, Etoposide Phosphate, and Cisplatin in Treating Patients With Advanced or Recurrent Sex Cord-Ovarian Stromal Tumors

Ovarian Gynandroblastoma | Ovarian Sertoli-Leydig Cell Tumor | Ovarian Sex Cord Tumor With Annular Tubules | Ovarian Steroid Cell Tumor | Ovarian Granulosa Cell Tumor | Ovarian Sex Cord-Stromal Tumor | Ovarian Sex Cord-Stromal Tumor, Not Otherwise Specified

United States

Clinical Trials on Malignant Gastrointestinal Stromal Tumor

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