Clinical Trials on Malignant Pleural Effusions

Total 5271 results

Exelixis

Active, not recruiting

A Study of XL092 as Single-Agent and Combination Therapy in Subjects With Solid Tumors (STELLAR-001)

Renal Cell Carcinoma | Colorectal Cancer | Metastatic Castration-resistant Prostate Cancer | Hormone Receptor Positive Breast Carcinoma | Neoplasm Malignant

United States, Australia, Belgium, Czechia, France, Germany, Italy, Netherlands, Spain, United Kingdom
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

AMG 706 and Octreotide in Treating Patients With Low-Grade Neuroendocrine Tumors

Islet Cell Tumor | Gastrointestinal Carcinoid Tumor | Neoplastic Syndrome

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Maryland Cigarette Restitution Fund

Completed

Survivorship Promotion In Reducing IGF-1 Trial (SPIRIT)

Kidney Cancer | Breast Cancer | Pancreatic Cancer | Lung Cancer | Rectal Cancer | Prostate Cancer | Endometrial Cancer | Colon Cancer | Liver Cancer | Melanoma of Skin | Other Solid Malignant Tumors

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Terminated

T-Cell Depletion, Donor Hematopoietic Stem Cell Transplant (HSCT), and T-Cell Infusions in Treating Patients With Hematologic Cancer or Other Diseases

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Precancerous/Nonmalignant Condition | Secondary Myelofibrosis | Multiple Myeloma and Malignant Plasma Cell Neoplasms

United States
Federation Francophone de Cancerologie Digestive

Completed

Combination Chemotherapy as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors of the Duodenum or Pancreas That Cannot Be Removed By Surgery

Islet Cell Tumor | Gastrointestinal Carcinoid Tumor | Neoplastic Syndrome
University of Miami
University of Miami Sylvester Comprehensive Cancer Center

Withdrawn

Mohs and Immunofluorescence for Malignant Melanoma In Situ

Lentigo Maligna | Melanoma In Situ

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"

Pancreatic Adenocarcinoma | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Malignant Neoplasm | Recurrent Colorectal Carcinoma | Pancreatic Neuroendocrine Carcinoma | Malignant Head and Neck Neoplasm | Stage III Nasopharyngeal Carcinoma... and other conditions

United States
Dublin City University
Royal College of Surgeons, Ireland; Mater Misericordiae University Hospital

Active, not recruiting

Perioperative Exercise and Nutritional Optimisation Prehabilitation Before Surgery for Patients With Peritoneal Malignancy (PANO)

Ovarian Cancer | Colon Cancer | Appendix Cancer | Rectum Cancer | Peritoneal Malignancy

Ireland
University of Vermont
Medical University of South Carolina; University of Washington; University of...

Active, not recruiting

Communication During Hospitalization About Resuscitation Trial (CHART)

End Stage Renal Disease | Severe Life-limiting COPD | Severe Life-limiting Heart Failure | Severe Life-limiting Cirrhosis | Severe Life-limiting Malignancy | Severe Functional Impairment

United States
Washington University School of Medicine

Completed

Same-session MR-only Simulation and Treatment With MRI-guided Adaptive Palliative RadioTherapy (MAP-RT)

Metastasis | Gastrointestinal Bleeding | Malignancy | Pelvic Bleeding | Hemoptysis | Superior Vena Cava Syndrome | Mediastinal Disease

United States
Matthew Dallos
Bristol-Myers Squibb

Terminated

Anti-Interleukin-8 (Anti-IL-8) for Patients With COVID-19

Solid Tumor | Sars-CoV2 | Hematological Malignancy

United States
Immunovative Therapies, Ltd.
Hadassah Medical Organization

Completed

A Phase I/II Study of Mis-Matched Immune Cells (AlloStim) in Patients With Advanced Hematological Malignancy

Lymphoma | Leukemia | Multiple Myeloma | Hematological Malignancy

Israel
M.D. Anderson Cancer Center

Recruiting

Radiofrequency Ablation for the Treatment of Benign or Low Risk Thyroid Nodule

Recurrent Thyroid Gland Carcinoma | Thyroid Gland Nodule | Thyroid Gland Papillary Carcinoma | Benign Thyroid Gland Neoplasm | Thyroid Gland Follicular Tumor of Uncertain Malignant Potential

United States
Ciusss de L'Est de l'Île de Montréal
Covid-19 Early Treatment Fund

Not yet recruiting

Cyproheptadine in Severe COVID-19 : A Unblinded Randomized Trial

Serotonin Syndrome | Platelet Dysfunction | Viral Pneumonia
Sabine Mueller, MD, PhD
National Cancer Institute (NCI); Dana-Farber Cancer Institute; Mithil Prasad... and other collaborators

Recruiting

ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors (PNOC023)

Glioblastoma | Recurrent Ependymoma | CNS Tumor | Diffuse Midline Glioma (DMG) | Recurrent Malignant Central Nervous System Neoplasm | Spinal Cord Glioma | Central Nervous System Tumor | World Health Organization (WHO) Grade III Glioma

United States, Switzerland
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Cancer Research UK; European Organisation for... and other collaborators

Active, not recruiting

Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors

Seminoma | Teratoma | Choriocarcinoma | Germinoma | Germ Cell Tumor | Yolk Sac Tumor | Mixed Germ Cell Tumor | Childhood Teratoma | Malignant Germ Cell Neoplasm | Extragonadal Seminoma | Non-seminomatous Germ Cell Tumor

United States, Germany, France, Spain, Netherlands, Australia, Belgium, Switzerland, United Kingdom, Italy, Denmark, Ireland
Gary Archer Ph.D.

Completed

Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma (ATTAC-P)

Glioblastoma | Malignant Glioma | Pediatric Brain Tumor | Medulloblastoma Recurrent | Pediatric Glioblastoma Multiforme | Pediatric Brain Tumor, Recurrent

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Everolimus, Letrozole and Trastuzumab in HR- and HER2/Neu-positive Patients

Advanced Malignant Solid Neoplasm | Recurrent Breast Carcinoma | Estrogen Receptor Positive | HER2/Neu Positive | Progesterone Receptor Positive | Stage IV Breast Cancer AJCC v6 and v7 | Postmenopausal | Stage IIIA Breast Cancer AJCC v7 | Stage IIIB Breast Cancer AJCC v7 | Stage IIIC Breast Cancer AJCC v7 and other conditions

United States
National Cancer Institute (NCI)

Terminated

Trastuzumab in Treating Patients With Locally Advanced or Metastatic Gallbladder Cancer or Bile Duct Cancer That Cannot Be Removed by Surgery

Malignant Neoplasm | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Adenocarcinoma of the Gallbladder | Adenocarcinoma of the Extrahepatic Bile Duct

United States
Northwestern University
National Cancer Institute (NCI)

Completed

Effect of Chemotherapy Given Either by Mouth or by Infusion on the Quality of Life of Patients With Recurrent Ovarian Epithelial Cancer

Quality of Life | Ovarian Cancer | Malignant Tumor of Peritoneum

United States
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Malignant Solid Neoplasm | Nasopharyngeal Carcinoma | Adenoid Cystic Carcinoma | Transitional Cell Carcinoma | Cholangiocarcinoma | Intrahepatic Cholangiocarcinoma | Chordoma | Gestational Trophoblastic Tumor | Pseudomyxoma Peritonei | Cervical Adenocarcinoma | Vaginal Adenocarcinoma | Vaginal Squamous Cell... and other conditions

United States, Guam
Melanoma and Skin Cancer Trials Limited
Melanoma Institute Australia

Completed

Radiotherapy or Imiquimod in Complex Lentigo Maligna (RADICAL)

Lentigo Maligna

Australia, Brazil, New Zealand
Centre Hospitalier Universitaire de Nice

Completed

Prospective Study of Ingenol Mebutate for Non-invasive Lentigo Melanoma of the Face (PICAMEL)

Lentigo Maligna

France
University of Utah

Completed

Combination Therapy With Imiquimod Cream 5% and Tazarotene Cream 0.1% for the Treatment of Lentigo Maligna

Cancer | Lentigo Maligna

United States
Jerry Marsden
Department of Health, United Kingdom

Completed

Effect of Topical Imiquimod on Lentigo Maligna (LIMIT-1)

Lentigo Maligna

United Kingdom
Mount Sinai Hospital, Canada

Active, not recruiting

Venous Thromboembolism in Hematologic Malignancy and Hematopoietic Cell Transplant Patients: a Retrospective Study

Thrombocytopenia | Hematologic Malignancy | Venous Thromboembolic Disease | Thrombosis, Venous | Bleeding Hemorrhage

Canada
Assistance Publique - Hôpitaux de Paris
Institut Pasteur, Paris France

Completed

PET/CT Guided Antifungal Stewardship in Invasive Pulmonary Aspergillosis (OPTIFIL)

Aspergillosis and Haematological Malignancy

France
University of Pittsburgh
Community Living And Support Services; Community LIFE

Recruiting

The Impact of Community-based Wellness Programs on The Triple Aim

Cerebral Palsy | Traumatic Brain Injury | Spinal Cord Injury | Spina Bifida

United States
University of Pittsburgh
Department of Health and Human Services

Recruiting

Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions

Cerebral Palsy | Brain Injuries | Traumatic Brain Injury | Spinal Cord Injuries | Spinal Dysraphism | Spina Bifida

United States
The University of Texas Health Science Center,...

Completed

Extended Criteria For Fetal Myelomeningocele Repair

Obesity | Pregnancy | Myelomeningocele | Diabetes Mellitus in Pregnancy | Fetal Anomaly

United States
Hacettepe University

Completed

Investigation of the Effects of Exercise on Patients With Chiari Malformation

Exercise Addiction | Proprioceptive Disorders | Syringomyelia | Chiari Malformation Type I | Coordination and Balance Disturbances | Basilar Invagination | Atlanto-Axial Subluxation

Turkey
Washington University School of Medicine

Completed

A Wheelchair Propulsion Training Program (HS)

Multiple Sclerosis | Amputation | Spinal Cord Injuries | Spina Bifida

United States
Northwestern University
Chicago Run; American Academy of Cerebral Palsy and Developmental Medicine; Spencer...

Enrolling by invitation

Ready, Set, Go! A Physical Fitness Intervention for Children With Mobility Challenges

Cerebral Palsy | Gross Motor Development Delay | Motor Skills Disorders | Myelomeningocele | Arthrogryposis

United States
Beijing Tongren Hospital

Unknown

Comparison of Four Questionnaires for OSA Screening in China (COQ)

Chiari Malformation | Questionnaire | Organic Obstructive Sleep Apnea (Diagnosis)
Skin Care Network Ltd.

Completed

Reflectance Confocal Microscopy to Diagnose MM & LM

Melanoma (Skin) | Lentigo Maligna

United Kingdom
Nykode Therapeutics ASA
Roche Pharma AG; GOG Foundation

Recruiting

Efficacy and Safety of VB10.16 Alone or in Combination With Atezolizumab in Patients With Advanced Cervical Cancer.

Cervical Cancer | HPV-Related Malignancy | HPV-Related Cervical Carcinoma

United States
First Affiliated Hospital of Jinan University
Ruijin Hospital

Recruiting

Sodium Stibogluconate in the MDS/AML With One of the 65 Defined p53 Mutations

Acute Myeloid Leukemia | Myelodysplastic Syndromes | P53 Mutation | Myeloid Malignancy | Temperature-Sensitive p53 Mutation | Sodium Stibogluconate

China
iCell Gene Therapeutics
The General Hospital of Western Theater Command; Peking University Shenzhen... and other collaborators

Recruiting

CLL1-CD33 cCAR in Patients With Relapsed and/or Refractory, High Risk Hematologic Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myeloid Leukemia | Hematologic Malignancy | Myeloproliferative Neoplasm

China
Hangzhou Sumgen Biotech Co., Ltd.

Active, not recruiting

SG301 Safety Study in Subjects With Relapsed or Refractory Multiple Myeloma and Other Hematological Malignancies

Relapsed or Refractory Multiple Myeloma | Hematological Malignancy

China
Centre Hospitalier de Cornouaille

Completed

Efficacy and Safety of the Anti- COVID-19 Vaccin in Clinical Hematology Patients (HEMVACO)

Covid19 | Hematologic Malignancy | Vaccine Response Impaired

France
University of California, San Francisco

Terminated

Pilot Trial of Clofarabine Added to Standard Busulfan and Fludarabine for Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation

Myeloid Malignancy | Metabolic Disease | Bone Marrow Failure Syndrome | Transfusion-dependent Red Blood Cell (RBC) Defect | Congenital Immunodeficiency | Severe Immune Dysregulation

United States
University of British Columbia

Recruiting

Polyomic Biomarker Verification in Adult Chronic Graft-Versus-Host Disease (ABLE3.0/CTTC2201)

Leukemia | Allogeneic Hematopoietic Stem Cell Transplantation | Blood Cancer | Chronic Graft-versus-Host-Disease | Non-Malignant Hematologic and Lymphocytic Disorder

United States, Canada
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Vemurafenib, Cobimetinib, Atezolizumab, and Tiragolumab in Treating Patients With High-Risk Stage III Melanoma

Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Pathologic Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIA Cutaneous Melanoma...

United States
Sabine Mueller, MD, PhD
Pacific Pediatric Neuro-Oncology Consortium; Curis, Inc.; Cannonball Kids' Cancer...

Active, not recruiting

Fimepinostat in Treating Brain Tumors in Children and Young Adults (PNOC016)

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Diffuse Intrinsic Pontine Glioma | Recurrent Anaplastic Astrocytoma

United States, Switzerland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Stereotactic Radiosurgery in Treating Patients With Greater Than 3 Melanoma Brain Metastases

Metastatic Melanoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Pathologic Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Malignant Neoplasm in the Brain

United States
University Medicine Greifswald

Completed

Nutrition in Gastrointestinal Tumors (NutriGIT)

Gastric Cancer | Pancreatic Cancer | Small Intestine Cancer | Rectal Cancer | Neuroendocrine Tumors | Bile Duct Cancer | Colon Cancer | Liver Cancer | Oesophageal Cancer | GIST, Malignant

Germany
Roswell Park Cancer Institute

Completed

Cisplatin in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer or Lung Metastasis

Stage IIIB Non-Small Cell Lung Cancer | Stage IV Non-Small Cell Lung Cancer | Stage IV Adult Soft Tissue Sarcoma | Metastatic Malignant Neoplasm in the Lung

United States
Five Prime Therapeutics, Inc.
Bristol-Myers Squibb

Completed

Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers (FPA008-003)

Renal Cell Carcinoma | Head and Neck Cancer | Pancreatic Cancer | Ovarian Cancer | Malignant Glioma | Advanced Solid Tumors | Non-small Cell Lung Cancer

United States
DNAtrix, Inc.
Merck Sharp & Dohme LLC

Completed

Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects (CAPTIVE)

Nervous System Diseases | Glioma | Glioblastoma | Neuroectodermal Tumors | Brain Cancer | Gliosarcoma | Brain Neoplasm | Malignant Brain Tumor | Neoplasm, Neuroepithelial | Neoplasm by Histologic Type | Neoplasm, Nerve Tissue

United States, Canada
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Nintedanib in Treating Patients With Recurrent or Persistent Endometrial Cancer

Recurrent Uterine Corpus Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Undifferentiated Carcinoma | Endometrial Adenocarcinoma | Endometrial Transitional Cell Carcinoma | Endometrial Mucinous Adenocarcinoma | Endometrial Squamous Cell Carcinoma | Malignant Uterine Corpus Mixed Epithelial and Mesenchymal Neoplasm

United States

Clinical Trials on Malignant Pleural Effusions

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Belgium

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations