Clinical Trials on Melanoma, Experimental

Total 3285 results

Biocad

Unknown

A Multicenter Open-Label Single-Arm Multi-Cohort Phase I Study of BCD-100 in Patients With Advanced Solid Tumors

Melanoma | Renal Cell Carcinoma | Lung Cancer

Russian Federation
Xencor, Inc.
ICON plc

Active, not recruiting

A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3) (DUET-3)

Renal Cell Carcinoma | Nasopharyngeal Carcinoma | Small Cell Lung Cancer | Hepatocellular Carcinoma | Advanced Solid Tumors | Non-small Cell Lung Carcinoma | Squamous Cell Carcinoma of the Head and Neck | Cervical Carcinoma | Endometrial Carcinoma | Urothelial Carcinoma | Colorectal Carcinoma | Pancreatic Carcinoma and other conditions

United States
Xynomic Pharmaceuticals, Inc.

Not yet recruiting

XP-102 and XP-102 in Combination With Trametinib in Advanced Solid Tumor Patients With a BRAF V600 Mutation (ENHANCE)

Melanoma | Cancer | Colorectal Cancer | Nonsmall Cell Lung Cancer | Thyroid Cancer | BRAF V600 Mutation
National Cancer Institute (NCI)

Completed

T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-DP0401 Positive

Melanoma | Cervical Cancer | Breast Cancer | Renal Cancer | Urothelial Cancer

United States
Università Politecnica delle Marche

Unknown

Immune Related-adverse Events in Patients Receiving Immune Checkpoint Inhibitors (ICI-DISCOVER)

Melanoma | Renal Cell Carcinoma | Cancer | Lung Cancer

Italy
Duke University

Completed

Interleukin-2-Induced Cognitive/Affective/Sleep Symptoms

Metastatic Renal Cell Carcinoma | Metastatic Melanoma | High-dose Interleukin-2

United States
Massachusetts General Hospital

Enrolling by invitation

Pilot Study of Imaging Human Skin With High-Speed Spectrally Encoded Confocal Microscopy

Skin Lesion | Pigmented Lesions | Pigmented Skin Lesion | Pigmented Moles

United States
Indonesia University

Completed

Comparison Between Free Thyroxine and Thyroid Stimulating Hormone Levels on Melasma Severity

Melasma

Indonesia
Nova Scotia Health Authority

Unknown

Genetic Identification (ID) of Segmental Dysplastic Nevi

Segmental Dysplastic Nevi

Canada
OrienGene Biotechnology Ltd.
Beijing Bozhiyin T&S Co., Ltd.; START Shanghai

Completed

A Phase I Study of Recombinant hGM-CSF Herpes Simplex Virus to Treat Cancer

Melanoma | Pancreatic Cancer | Lung Cancer | Liver Cancer

China
Inhibrx, Inc.
Merck Sharp & Dohme LLC

Recruiting

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

Melanoma | Renal Cell Carcinoma | Head and Neck Cancer | Gastric Cancer | Non-Small Cell Lung Cancer | Solid Tumor | Urothelial Carcinoma

United States
Inhibrx, Inc.

Recruiting

Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer (PDL1x41BB)

Melanoma | Renal Cell Carcinoma | Nasopharyngeal Carcinoma | Gastric Adenocarcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Adenocarcinoma | Metastatic Solid Tumors | Oropharyngeal Carcinoma

United States
Novartis Pharmaceuticals

Active, not recruiting

Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors.

Melanoma | Carcinoma, Non-Small-Cell Lung | Nasopharyngeal Carcinoma | Triple Negative Breast Cancer | Microsatellite Stable Colorectal Cancer

United States, Taiwan, Spain, Germany, Japan, Hong Kong
Genocea Biosciences, Inc.

Terminated

TiTAN-1: Safety, Proliferation and Persistence of GEN-011 Autologous Cell Therapy

Melanoma | Renal Cell Carcinoma | Squamous Cell Carcinoma of Head and Neck | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Urothelial Carcinoma | Anal Squamous Cell Carcinoma | Merkel Cell Carcinoma | Cutaneous Squamous Cell Carcinoma

United States
MacroGenics

Completed

Safety Study of MGA271 in Refractory Cancer

Melanoma | Renal Cell Carcinoma | Head and Neck Cancer | Prostate Cancer | Bladder Cancer | Non-small Cell Lung Cancer | Triple-negative Breast Cancer

United States
Emory University

Completed

Videoscopic Versus Open Inguinal Lymphadenectomy for Cancer

Melanoma | Vulvar Cancer | Skin Cancer | Lymphadenopathy | Anal Cancer | Merkel Cell Carcinoma | Squamous Cell Carcinoma | Penile Carcinoma | Urethral Carcinoma | Extramammary Paget's Disease | Scrotal Carcinoma

United States
National Cancer Institute (NCI)

Completed

A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors

Melanoma | Sarcoma | Osteosarcoma | Neuroblastoma

United States
AstraZeneca

Completed

A Study to Assess the Safety, Tolerability and Anti-tumour Activity of Ascending Doses of Selumetinib in Combination With MEDI4736 and Selumetinib in Combination With MEDI4736 and Tremelimumab in Patients With Advanced Solid Tumours

Melanoma | Breast Cancer | Colorectal Cancer | Pancreatic Adenocarcinoma | Lung Cancer | Head and Neck Carcinoma | Biliary Tract Cancer | Gastroesophageal Cancer

United States
Nektar Therapeutics
Bristol-Myers Squibb

Completed

A Dose Escalation and Cohort Expansion Study of NKTR-214 in Combination With Nivolumab and Other Anti-Cancer Therapies in Patients With Select Advanced Solid Tumors (PIVOT-02)

Melanoma | Renal Cell Carcinoma | Gastric Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Urothelial Carcinoma | HR+/HER2- Breast Cancer

United States, Spain, Canada, France, Italy, Belgium, Poland, United Kingdom
Seagen Inc.
Merck Sharp & Dohme LLC

Recruiting

Brentuximab Vedotin With Pembrolizumab in Metastatic Solid Tumors

Melanoma | Squamous Cell Carcinoma of the Head and Neck | Non-small Cell Lung Cancer

United States, Canada
National Cancer Institute (NCI)

Completed

Retinoblastoma Biomarker Study

Melanoma | Sarcoma | Retinoblastoma

United States
National Cancer Institute (NCI)

Enrolling by invitation

Prospective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor Microenvironment

Melanoma | Pancreatic Cancer | Lung Cancer | Solid Tumors | Gastrointestinal Cancer | Hematologic Malignancy | Liver Cancer | Pre-Malignancy

United States
Seagen Inc.

Terminated

A Study of SGN-CD228A in Advanced Solid Tumors

Colorectal Cancer | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma | Cutaneous Melanoma | Pleural Mesothelioma | HER2 Negative Breast Neoplasms

United States, Spain, France, Italy, United Kingdom
Jinnah Postgraduate Medical Centre

Completed

Comparison of Efficacy of Tranexamic Acid Mesotherapy Versus 0.9% Normal Saline for Melasma

Effect of Drugs | Adverse Effects of Medical Drugs

Pakistan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

Prognostic Stage IIIC Breast Cancer AJCC v8 | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Melanoma | Stage IV Lung Cancer AJCC v8 | Locally Advanced Malignant Solid Neoplasm | Locally... and other conditions

United States
Adaptimmune

Active, not recruiting

MAGE-A4ᶜ¹º³²T for Multi-Tumor

Melanoma | Head and Neck Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Urinary Bladder Cancer | Synovial Sarcoma | Gastroesophageal Junction | Myxoid Round Cell Liposarcoma

United States, Canada
Fore Biotherapeutics

Terminated

Phase I/IIa Study to Evaluate the Safety, PK, PD, and Preliminary Efficacy of PLX8394 in Patients With Advanced Cancers.

Melanoma | Colorectal Cancer | Cholangiocarcinoma | Non-small Cell Lung Cancer | Histiocytosis | Thyroid Cancer | Hairy Cell Leukemia

United States
TScan Therapeutics, Inc.

Recruiting

A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors

Melanoma | Cervical Cancer | Head and Neck Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | HPV16 Related Cancers

United States
The Christie NHS Foundation Trust
University of Manchester

Recruiting

NOTION: iN-home Sampling Of cyTokines in ImmunOtherapy patieNts

Renal Cell Carcinoma | Cancer | Metastatic Melanoma | Non-small Cell Lung Cancer

United Kingdom
Iovance Biotherapeutics, Inc.

Recruiting

Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors

Squamous Cell Carcinoma of the Head and Neck | Metastatic Melanoma | Non-small Cell Lung Cancer

United States, Spain, Canada, France, Germany, Greece, Switzerland, United Kingdom
National Cancer Institute (NCI)

Terminated

Messenger RNA (mRNA)-Based, Personalized Cancer Vaccine Against Neoantigens Expressed by the Autologous Cancer

Melanoma | Colon Cancer | Gastrointestinal Cancer | Hepatocellular Cancer | Genitourinary Cancer

United States
Clinica Universidad de Navarra, Universidad de...

Unknown

Phase II Study With Immunotherapy With Dendritic Cells and Tumor Infiltrating Lymphocytes in Solid Tumors

Melanoma | Renal Cell Carcinoma | Carcinoma, Hepatocellular

Spain
Bristol-Myers Squibb

Withdrawn

An Investigational Study of Infliximab With Prednisone or Methylprednisolone Versus Prednisone Combination Treatment in Immune Related or Severe Diarrhea in Patients Treated With Yervoy and/or Opdivo

Melanoma | Renal Cell Carcinoma | Lung Cancer

United States
Elucid Labs Inc.

Unknown

Elucid Labs AIDA™ - Labelled Image Acquisition Protocol

Melanoma (Skin) | Squamous Cell Carcinoma of the Skin | Basal Cell Carcinoma of the Skin

Canada
Neotherix Limited
NAMSA; Innovate UK; Lorien Engineering Solutions (a division of GP Strategies... and other collaborators

Completed

EktoTherix™ Regenerative Tissue Scaffold for Repair of Surgical Excision Wounds

Basal Cell Carcinoma | Squamous Cell Carcinoma | Non-melanoma Skin Cancer

United Kingdom
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Teenage/Young Adults and Paediatric Patients With ROS1 Gene Fusion-positive Cancers. (DETERMINE)

Glioma | Melanoma | Neoplasms by Histologic Type | Lymphoproliferative Disorders | Neoplasms by Site | Cancer | Brain Neoplasms | Solid Tumor | Malignant Neoplasm | Malignancy | Haematological Malignancy

United Kingdom
Jason J. Luke, MD
Bristol-Myers Squibb

Recruiting

Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors

Melanoma | Carcinoma, Renal Cell | Unresectable Solid Tumors

United States
St. Jude Children's Research Hospital
University of Wisconsin, Madison

Completed

Pretreatment Anti-Therapeutic Antibodies (PATA) in Patients Treated With hu14.18K322A Antibody

Melanoma | Osteosarcoma | Neuroblastoma | Ewing Family of Tumors

United States
MacroGenics

Active, not recruiting

A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors (Tamarack)

Melanoma | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Anal Cancer | Malignant Melanoma | Non-small Cell Carcinoma | Oral Squamous Cell Carcinoma | Small Cell Carcinoma | Laryngeal Squamous Cell Carcinoma | Carcinoma, Squamous Cell of Head and Neck | Castration-Resistant... and other conditions

Spain, Australia, United States, Korea, Republic of, France, United Kingdom, Italy, Belgium, Poland
Dr.dr.Irma Bernadette, SpKK (K)

Completed

Comparative Study of mMASI Before and After Hyperthyroid Therapy in Hyperthyroid Subjects With Melasma

Hyperthyroidism | Melasma

Indonesia
AdventHealth Translational Research Institute

Recruiting

Exercise to Boost Response to Checkpoint Blockade Immunotherapy (EX-BOOST)

Merkel Cell Carcinoma | Cutaneous Melanoma | Cutaneous Squamous Cell Carcinoma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Melanoma Research Alliance

Completed

PET Quantitative Assessments of Solid Tumor Response to Immune Checkpoint Blockade Therapy

Melanoma | Non-small Cell Lung Cancer (NSCLC) | Renal Cell Carcinoma (RCC)

United States
Central Hospital, Nancy, France

Unknown

ACCEPTABILITY AND WRITING FREQUENCY OF ADVANCED DIRECTIVES IN ONCO-DERMATOLOGY PATIENTS (PADAONCODERM)

Melanoma | Skin Cancer | Oncology | Skin Squamous Cell Carcinoma | Advance Directives | Skin Lymphoma | Metastatic Basal Cell Carcinoma

France
Genentech, Inc.

Completed

A Study of the Safety, Tolerability, and Effects of Cobimetinib and GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors

Non-Small Cell Lung Cancer, Metastatic Colorectal Cancer, Metastatic Non Small Cell Lung Cancer, Metastatic Cancers, Melanoma

United States
Mayo Clinic

Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors (PNeoVCA)

Metastatic Renal Cell Carcinoma | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 and other conditions

United States
Kantonsspital Winterthur KSW
Luzerner Kantonsspital

Not yet recruiting

Skin Cancer and Hyperthermia and Radiotherapy (SAHARA)

Basal Cell Carcinoma | Non-melanoma Skin Cancer | Squamous Cell Carcinoma Skin

Switzerland
Ohio State University Comprehensive Cancer Center

Recruiting

EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin Cancers

Merkel Cell Carcinoma | Cutaneous Melanoma | Skin Squamous Cell Carcinoma

United States
ImaginAb, Inc.
University of Hull

Recruiting

CD8 Minibody Repeatability Study (PRETZCEL)

Melanoma | Renal Cell Carcinoma

United Kingdom
Charite University, Berlin, Germany
Klinikum rechts der Isar, TU München, (TUM), Munich, Germany.

Recruiting

Heat Shock Protein (HSP) 70 to Quantify and Characterize Circulating Tumor Cells (HSP70CTC)

Sarcoma | Prostate Cancer | Pancreatic Cancer Stage IV | Breast Cancer Stage IV | Squamous Cell Carcinoma | Melanoma Stage IV

Germany
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Withdrawn

Assessment of Current Biomarker Testing Practices for Common Solid Cancers in Precision Oncology in the Community Setting

Melanoma | Breast Carcinoma | Lung Carcinoma | Colorectal Carcinoma | Community Practice | Solid Neoplasm

United States

Clinical Trials on Melanoma, Experimental

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