Clinical Trials on Melanoma and Brain Metastases in Belgium

Total 1029 results

HUYABIO International, LLC.
Bristol-Myers Squibb

Recruiting

Study Comparing Investigational Drug HBI-8000 Combined With Nivolumab vs. Nivolumab in Patients With Advanced Melanoma

Unresectable or Metastatic Melanoma | Progressive Brain Metastasis

Spain, United States, Italy, Japan, Belgium, France, New Zealand, Brazil, Korea, Republic of, Australia, Germany, Singapore, Czechia, Austria, South Africa, United Kingdom, Puerto Rico
Pfizer

Terminated

An Open-Label, Randomized, Multicenter Trial of Encorafenib + Binimetinib Evaluating a Standard-dose and a High-dose Regimen in Patients With BRAFV600-mutant Melanoma Brain Metastasis (POLARIS)

Brain Metastases

United States, Belgium, Australia, Argentina, Italy
Universitaire Ziekenhuizen KU Leuven

Recruiting

Local Ablative Therapy for Patients With Multiple (4-10) Brain Metastases (LAT-MUM)

Brain Metastases, Adult

Belgium
Universitair Ziekenhuis Brussel

Recruiting

Evaluation of 68-GaNOTA-Anti-HER2 VHH1 Uptake in Brain Metastasis of Cancer Patients

Carcinoma | Receptor, ErbB-2

Belgium
Jules Bordet Institute
Bristol-Myers Squibb; La Fondation contre le cancer, Belgique; Les Amis de l'Institut... and other collaborators

Recruiting

A Brain Metastases Research Platform to Tackle the Challenge of CNS Metastases in Solid Tumours (BrainStorm)

CNS Metastases

Belgium, France, Luxembourg
University Hospital, Ghent
Flemish institute of biotechnology (VIB)

Recruiting

Single-Cell Transcriptomics of the Peritoneal Microenvironment of Colorectal PC (SingleCell)

Peritoneal Metastases

Belgium
Celyad Oncology SA

Terminated

Hepatic Transarterial Administrations of NKR-2 in Patients With Unresectable Liver Metastases From Colorectal Cancer (LINK)

Colon Cancer Liver Metastasis

Belgium
Jules Bordet Institute
GlaxoSmithKline; Schering-Plough

Completed

Lapatinib and Temozolomide for the Treatment of Progressive Brain Disease in HER-2 Positive Breast Cancer (LAPTEM)

Metastatic Breast Cancer | Brain Metastases | HER2 Positive

Belgium
Universitair Ziekenhuis Brussel

Completed

Intratumoral Injection of Autologous CD1c (BDCA-1)+ myDC, Avelumab, and Ipilimumab Plus Systemic Nivolumab (myDAvIpNi)

Solid Tumor | Metastases to Soft Tissue

Belgium
Celyad Oncology SA

Unknown

Dose Escalation and Dose Expansion Phase I Study to Assess the Safety and Clinical Activity of Multiple Doses of NKR-2 Administered Concurrently With FOLFOX in Colorectal Cancer With Potentially Resectable Liver Metastases (SHRINK)

Colon Cancer Liver Metastasis

Belgium
Universitair Ziekenhuis Brussel

Recruiting

A Clinical Trial of Regorafenib in Patients With Pretreated Advanced Melanoma (RegoMel)

Melanoma Stage IV | Melanoma Stage III

Belgium
Universitair Ziekenhuis Brussel

Completed

TraMel-WT: A Trial of Trametinib in Patients With Advanced Pretreated BRAFV600 Wild-type Melanoma (TraMel-WT)

Stage IV Melanoma | Stage III Melanoma

Belgium
Jules Bordet Institute
Sanofi

Withdrawn

Evaluation of Cabazitaxel in Patients With Brain Metastasis Secondary to Breast Cancer and NSCLC (CRANIAL)

Breast Cancer | Non Small Cell Lung Cancer | Brain Metastasis

Belgium
Ludwig Institute for Cancer Research

Terminated

Immunization With 8 Peptides Mixed With CpG 7909 or Montanide ISA51 in Patients With Metastatic Cutaneous Melanoma

Malignant Melanoma

Belgium
Ludwig Institute for Cancer Research

Terminated

Immunization With the MAGE-3.A1 Peptide Mixed With the Adjuvant CpG 7909 in Patients With Metastatic Melanoma

Malignant Melanoma

Belgium
Cliniques universitaires Saint-Luc- Université...

Terminated

Peptide Vaccination Associated With Tumoral Immunomodulation in Patients With Advanced Metastatic Melanoma

Metastatic Melanoma

Belgium
Janssen Research & Development, LLC
PharmaMar

Completed

A Study to Assess the Potential Effects of Ketoconazole on the Pharmacokinetics of Trabectedin in Patients With Advanced Malignancies

Neoplasm Metastases

Belgium
Universitaire Ziekenhuizen KU Leuven

Recruiting

SBRT in the Management of Solid Spinal Metastases

Spinal Metastases | Extradural Tumor

Belgium
Universitair Ziekenhuis Brussel
RIZIV

Completed

mRNA Electroporated Autologous Dendritic Cells for Stage III/IV Melanoma (DC-MEL)

Malignant Melanoma Stage III | Malignant Melanoma Stage IV

Belgium
Bart Neyns
Vrije Universiteit Brussel

Completed

Autologous TriMix-DC Therapeutic Vaccine in Combination With Ipilimumab in Patients With Previously Treated Unresectable Stage III or IV Melanoma (TriMix-Ipi)

Malignant Melanoma Stage III | Malignant Melanoma Stage IV

Belgium
Cliniques universitaires Saint-Luc- Université...

Terminated

Peptide Vaccinations Plus GM-CT-01 in Melanoma

Metastatic Melanoma

Belgium
Universitair Ziekenhuis Brussel

Completed

Dabrafenib and Trametinib for BRAF-inhibitor Pretreated Patients

Malignant Melanoma

Belgium
Universitair Ziekenhuis Brussel

Recruiting

Biomarkers for the Activity of Immune Checkpoint Inhibitor Therapy in Patients With Advanced Melanoma (ICIT)

Malignant Melanoma

Belgium
European Organisation for Research and Treatment...

Terminated

Vaccine Therapy in Treating Patients With Melanoma of the Eye

Intraocular Melanoma

Belgium, Denmark
Cancer Research Antwerp

Completed

A Trial to Improve Quality of Life With Stereotactic Body Radiotherapy for Patients With Painful Bone Metastases (ROBOMET)

Neoplasm Metastasis | Radiotherapy | Metastasis to Bone

Belgium
BBB-Therapeutics B.V.

Completed

An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma.

Melanoma | Breast Cancer | Lung Cancer | Malignant Glioma | Brain Metastases

United States, Netherlands, France, Belgium
Bayer

Completed

Extension Program for Bay 43-9006

Metastasis | Neoplasm

Canada, Belgium, Germany, United States
University Hospital, Ghent

Terminated

Hair-sparing Whole Brain Radiotherapy

Small Cell Lung Cancer | Brain Metastases

Belgium
Universitair Ziekenhuis Brussel

Completed

A Clinical Trial: Adjuvant Low-dose Ipilimumab + Nivolumab After Resection of Melanoma Macrometastases (ipniv)

Stage IV Skin Melanoma | Stage IIIC Skin Melanoma

Belgium
Medical Device Works NV SA
Celerion; Cromsource

Unknown

Liver-PILP First-in-Man (PILP FiM)

Liver Metastases

Belgium
Tools4Patient

Completed

A Study to Collect Data About Analgesia in Patients With Bone Metastasis

Bone Metastasis

Belgium, France
University Hospital, Ghent

Completed

Biological Imaging Guided Antalgic Radiotherapy of Bone Metastases (Phase II Trial)

Bone Metastases

Belgium
University Hospital, Ghent

Unknown

Biological Image Guided Antalgic Stereotactic Body Radiotherapy of Bone Metastases

Bone Metastases

Belgium
University Hospital, Ghent

Terminated

A Feasibility Study on the Use of F-18-FDG-PET and Optical Imaging in Evaluation of Radiation-induced Oral Mucositis

Squamous Cell Carcinoma of the Oral Cavity | Oropharynx Metastases | Lymph Metastases

Belgium
Universitair Ziekenhuis Brussel
Kom Op Tegen Kanker

Recruiting

Phase I/IIa Study of 68GaNOTA-Anti-MMR-VHH2 for PET/CT

Breast Cancer | Melanoma (Skin) | Malignant Solid Tumor

Belgium
University Ghent

Completed

Whole Breast + Lymph Node Irradiation: Prone Compared to Supine Position in 15 or 5 Fractions (PRO-SURF)

Breast Neoplasms | Lymph Node Metastases | Radiotherapy

Belgium
Nektar Therapeutics

Completed

A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine (ATTAIN)

Breast Cancer | Metastasis

United States, Australia, Belgium, Canada, France, Israel, Italy, Portugal, Spain, United Kingdom
BioNTech US Inc.

Recruiting

NEO-PTC-01 in Patients With Advanced or Metastatic Melanoma

Metastatic Melanoma | Unresectable Melanoma

Belgium, Netherlands, Spain
Cliniques universitaires Saint-Luc- Université...
Immutep S.A.S.

Terminated

Immunization of Disease-Free Melanoma Patients With Different HLA-A2 Peptides

Melanoma

Belgium
Cliniques universitaires Saint-Luc- Université...
Institut Pasteur

Unknown

Safety and Toxicity Study of Vaccination for Advanced Metastatic Melanoma Patients (THERAVAC)

Melanoma

Belgium
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Completed

Vitamin D Supplementation in Cutaneous Malignant Melanoma Outcome (ViDMe)

Cutaneous Malignant Melanoma

Belgium, Hungary
Cliniques universitaires Saint-Luc- Université...

Completed

Whole-Body 3D T1-weighted MR Imaging Anatomical Sequences: GE mDixon vs FSE (View) Approaches in Prostate Cancer. (TFE-TVE)

Metastasis | Prostate Adenocarcinoma

Belgium
University Hospital, Ghent
Jessa Hospital; University Hospital, Antwerp; AZ Sint-Jan AV; AZ Delta; General Hospital... and other collaborators

Terminated

BLood Groups as Biomarker to Optimize Odds of Response to Anti-PD-1 Drugs (BLOOD)

Melanoma | Cancer

Belgium
Universitair Ziekenhuis Brussel

Active, not recruiting

Intratumoral Injection of Autologous CD1c (BDCA-1)+ Myeloid Dendritic Cells Plus Talimogene Laherparepvec (T-VEC) (myDCTV)

Melanoma

Belgium
KU Leuven
Jules Bordet Institute; Erasme University Hospital; GZA Ziekenhuizen Campus Sint-Augustinus

Not yet recruiting

Clinical, Histological and In-depth Molecular Characterization as Well as Experimental Models of Liver Metastasis From Patients With Breast Cancer in Order to Identify New Potential Treatment Avenues. (OLiver Pro)

Breast Cancer | Liver Metastases

Belgium
Bart Neyns

Completed

A Study on the Safety and Immunogenicity of Combined Intradermal and Intravenous Administration of an Autologous mRNA Electroporated Dendritic Cell Vaccine in Patients With Previously Treated Unresectable Stage III or IV Melanoma

Melanoma

Belgium
Universitaire Ziekenhuizen KU Leuven

Unknown

Metachronic Brain Metastases After Esophagectomy for Esophageal Cancer (METABREC) (METABREC)

Esophageal Neoplasms | Brain Metastases | Esophagectomy

United States, France, Netherlands, Sweden, Belgium, Ireland
Hoffmann-La Roche

Completed

A Study of the Effect of Vemurafenib on the Pharmacokinetics of Phenprocoumon in Patients With BRAFV600 Mutation-Positive Metastatic Malignancy

Malignant Melanoma, Neoplasms

Belgium, Spain, Germany, Netherlands, Finland
Universitair Ziekenhuis Brussel
University Hospital, Ghent

Recruiting

Dabrafenib/Trametinib/Hydroxychloroquine for Advanced Pretreated BRAF V600 Mutant Melanoma (COMBI-R2)

Melanoma

Belgium
Hoffmann-La Roche

Completed

A Study of RO7293583 in Participants With Unresectable Metastatic Tyrosinase Related Protein 1 (TYRP1)-Positive Melanomas

Uveal Melanoma | Cutaneous Melanoma | Mucosal Melanoma

Spain, United States, Belgium, Denmark, Canada, Australia

Clinical Trials on Melanoma and Brain Metastases in Belgium

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