Clinical Trials on Metabolic Syndrome X in United Kingdom

Total 34857 results

Soma Jyonouchi
Baylor College of Medicine

Completed

Interleukin-2 Treatment for Wiskott-Aldrich Syndrome (WAS)

X-linked Thrombocytopenia | Wiskott-Aldrich Syndrome (WAS)

United States
Cambridge University Hospitals NHS Foundation Trust

Recruiting

Low-dose Interleukin-2 for the Reduction of Vascular Inflammation in Acute Coronary Syndromes - IVORY (IVORY)

Acute Coronary Syndromes

United Kingdom
Washington University School of Medicine
National Center for Complementary and Integrative Health (NCCIH)

Completed

Yoga for the Management of HIV-Metabolic Syndromes

HIV Infections | Hypertension | HIV Lipodystrophy | HIV Metabolic Cardiovascular Syndrome | HIV Metabolic Syndromes

United States
Amicus Therapeutics

Completed

Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Migalastat in Pediatric Subjects (Aged 12 to <18 Years)

Fabry Disease

United Kingdom, United States
Amicus Therapeutics

Terminated

Open-label Long-term Safety Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease Who Have Completed a Previous AT1001 Study

Fabry Disease

United Kingdom, United States, Australia, Brazil, France
King's College London

Completed

Splenda: Effects on Blood Glucose Concentration, Appetite Scores and Subsequent Energy Intake

Glucose Metabolism Disorders | Appetitive Behavior

United Kingdom
King's College London
St Thomas' Hospital, London

Completed

Determination of Optimum Age for DXA Screening for Osteoporosis in HIV - The Probono 1 Study (Probono1)

HIV Infection | Osteoporosis | Fractures

United Kingdom
Children's Hospital Medical Center, Cincinnati

Completed

An Initial Study of AZD7325 in Adults With Fragile X Syndrome

Fragile X Syndrome

United States
Randi J. Hagerman, MD

Completed

Trial of Sertraline to Treat Children With Fragile X Syndrome

Fragile X Syndrome

United States
Indiana University
Indiana Clinical and Translational Sciences Institute

Completed

Riluzole in Fragile X Syndrome

Fragile X Syndrome

United States
Indiana University School of Medicine

Completed

A Prospective Open-label Study of Aripiprazole in Fragile X Syndrome

Fragile X Syndrome

United States
Stanford University
National Institute of Mental Health (NIMH); Autism Speaks

Completed

Randomized Controlled Study of Donepezil in Fragile X Syndrome

Fragile X Syndrome

United States
Minoryx Therapeutics, S.L.

Active, not recruiting

A Clinical Study to Evaluate the Efficacy and Safety of MIN-102 (IMP) in Male AMN Patients. (Advance)

Adrenoleukodystrophy

Spain, United States, Hungary, France, Germany, Italy, Netherlands, United Kingdom
King's College London

Unknown

Canderel:Effects on Blood Glucose Concentration and Appetite Scores

Glucose Metabolism Disorders | Appetitive Behavior

United Kingdom
King's College Hospital NHS Trust

Completed

The Efficacy and Safety of Lenalidomide Monotherapy in Red Blood Cell Transfusion Dependent Subjects With Myelodysplastic Syndrome (MDS) Associated With Del (5q) Abnormality

Myelodysplastic Syndromes

United Kingdom
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Extension Study of PRX-102 for up to 60 Months

Fabry Disease

United States, Spain, United Kingdom, Paraguay
Ultragenyx Pharmaceutical Inc

Terminated

Study to Assess the Long Term Safety and Efficacy of UX007 in Participants With Glucose Type 1 Deficiency Syndrome (Glut1 DS)

Glucose Transporter Type 1 Deficiency Syndrome

United States, Spain, Denmark, United Kingdom, Australia
Atlantia Food Clinical Trials
Caelus Pharmaceuticals BV

Completed

Efficacy and Safety of 12-weeks Supplementation of Eubacterium Hallii on Insulin Sensitivity and Glycaemic Control

Glucose Metabolism Disorders | Metabolic Syndrome | Insulin Resistance | Impaired Glucose Tolerance | Insulin Sensitivity | Pre Diabetes

Ireland, United States, United Kingdom
bluebird bio

Completed

A Study of the Efficacy and Safety of Hematopoietic Stem Cells Transduced With Lenti-D Lentiviral Vector for the Treatment of Cerebral Adrenoleukodystrophy (CALD)

Cerebral Adrenoleukodystrophy (CALD)

United States, Germany, Argentina, Australia, France, United Kingdom
Imperial College London
The Drummond Foundation (RAMC charity)

Recruiting

Chemical Analysis of Limb Microfluidics (CALM)

Compartment Syndrome of Leg | Limb Ischemia

United Kingdom
Allergan

Terminated

Clinical Study to Evaluate Tear Characteristics Following Acute TrueTear™ Use

Dry Eye Syndromes

United Kingdom
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (UK Only)

Dravet Syndrome

United Kingdom
Takeda

Recruiting

A Study Evaluating Soticlestat in Participants With Dravet Syndrome or Lennox-Gastaut Syndrome Who Have Been Exposed to Fenfluramine

Dravet Syndrome (DS) | Lennox-Gastaut Syndrome (LGS)

United Kingdom, Denmark
Neuropharm

Completed

Open Label Study Investigating Safety and Efficacy of NPL2009 50 mg - 150 mg on Prepulse Inhibition Tests and Continuous Performance Tasks, Adults With Fragile X Syndrome

Fragile X Syndrome

United States
Barts & The London NHS Trust
Cancer Research UK; Amgen

Unknown

Comparison Study of Standard Care Against Combination of Growth Factors Agents for Low-risk Myelodysplastic Syndromes (REGIME)

Myelodysplastic Syndrome

United Kingdom
Shire

Completed

Extension Study of TKT028 Evaluating Safety and Clinical Outcomes of Replagal® in Adult Patients With Fabry Disease

Fabry Disease

United States, Slovenia, Australia, Finland, Poland, Czechia, United Kingdom
Alexion Pharmaceuticals

Completed

A Retrospective Chart Review of Deceased Patients With Mucopolysaccharidosis Type IIIB

MPS IIIB (Sanfilippo Syndrome)

Spain, Netherlands, United Kingdom, United States, Brazil
Mayo Clinic

Completed

Metabolic Syndrome Diagnosis and Education Trial

Metabolic Cardiovascular Syndrome

United States
JCR Pharmaceuticals Co., Ltd.

Recruiting

A Phase III Study of JR-141 in Patients With Mucopolysaccharidosis II (STARLIGHT)

Mucopolysaccharidosis II

United States, Germany, Spain, France, Brazil, Argentina, Turkey, United Kingdom, Poland, Italy
University of Aberdeen

Active, not recruiting

Acute Study of Anthocyanin-rich Bilberry and Polyphenol-rich Apple Extracts on Postprandial Glycaemic Response

Glucose Metabolism Disorders | Glucose Intolerance

United Kingdom
University of Texas Southwestern Medical Center
Donald W. Reynolds Foundation

Completed

Dallas Heart Study 2: Return Clinic Visit for the Dallas Heart Study Cohort

Myocardial Infarction | Hypertension | Obesity | Diabetes Mellitus | Atherosclerosis | Congestive Heart Failure | Metabolic Syndrome X | Left Ventricular Hypertrophy

United States
Stanford University
The John Merck Fund

Completed

Treatment of Disruptive Behaviors in Fragile X Syndrome

Fragile X Syndrome | Disruptive Behavior

United States
Stanford University

Completed

Teaching Math Skills to Individuals With Fragile X Syndrome

Developmental Disabilities | Fragile X Syndrome

United States
Newcastle-upon-Tyne Hospitals NHS Trust
British Heart Foundation; University of Newcastle Upon-Tyne

Completed

Assessment of Thrombogenicity in Acute Coronary Syndrome

Type 2 Diabetes Mellitus | Acute Coronary Syndrome

United Kingdom
University Hospital Birmingham NHS Foundation Trust

Completed

The Application of Near Infrared Spectroscopy (NIRS) in the Detection of Lower Limb Compartment Syndrome

Compartment Syndrome

United Kingdom
Novartis Pharmaceuticals

Completed

Clinical Study to Assess the Pharmacokinetics, Safety and Tolerability of Single and Multiple Oral Doses of AFQ056 in Children With Fragile X Syndrome (FXS)

Fragile X Syndrome

United States, Spain
University of West London

Completed

Supplementary Vitamin B12 Effects on Elevated Homocysteine Levels of Vegetarians - Clinical Trial

Vitamin B12 Deficiency

United Kingdom
The Royal Wolverhampton Hospitals NHS Trust

Completed

An Investigation Into the Effect of Liquorice Ingestion on the Salivary Cortisol to Cortisone Molar Ratio

Apparent Mineralocorticoid Excess

United Kingdom
Acacia Pharma Ltd

Completed

Pilot Study of APD209 in Cancer Cachexia

Cancer-related Cachexia

United Kingdom
Ultragenyx Pharmaceutical Inc

Active, not recruiting

Long Term Follow Up to Evaluate DTX301 in Adults With Late-Onset OTC Deficiency (CAPtivate)

Ornithine Transcarbamylase (OTC) Deficiency

Canada, United States, France, Spain, United Kingdom
Hoffmann-La Roche

Completed

A Study to Investigate the Pharmacokinetics, Pharmacodynamic Effects, Safety and Tolerability of Repeated Dosing of RO5459072 in Volunteers With Celiac Disease

Celiac Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Recruiting

Remote Monitoring to Improve Low Adherence in Non-invasive Ventilation (READ-NIV)

Sleep Disordered Breathing | COPD | Hypercapnic Respiratory Failure | Obesity Hypoventilation Syndrome (OHS)

United Kingdom
University of Nottingham
Biotechnology and Biological Sciences Research Council

Recruiting

Multi-organ Responses to CHronic Physical Activity and INactivity (CHAIN)

Metabolic Syndrome | Sedentary Behavior | Age-related Cognitive Decline | Age-Related Sarcopenia

United Kingdom
King's College Hospital NHS Trust

Terminated

Pilot Study of Reduced Intensity Haematopoietic Stem Cell Transplantation in Patients With Poor Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukaemia (AML) Utilising Conditioning With Fludarabine, Busulphan and Thymoglobulin (FB-ATG)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

United Kingdom
Bio Products Laboratory

Completed

Pharmacokinetics (PK) and Safety of Subgam-VF in Primary Immunodeficiency Diseases (SCIG03)

Common Variable Immunodeficiency | Primary Immune Deficiency Disorders | X-linked Agammaglobulinaemia | Hyperimmunoglobulin M Syndrome

United States
University of the West of England
Royal United Hospital Bath NHS Trust

Completed

Self Soft Tissue Therapy for Fibromyalgia Syndrome

Fibromyalgia Syndrome

United Kingdom
University Hospitals, Leicester

Completed

Amount of Lactose Causing Symptoms in People With Lactose Intolerance and Ulcerative Colitis

Ulcerative Colitis | Lactose Intolerance

United Kingdom
Fred Hutchinson Cancer Center

Completed

Study of Total Body Irradiation and Fludarabine Followed By Allogeneic Peripheral Blood Stem Cell or Bone Marrow Transplantation in Combination With Cyclosporine and Mycophenolate Mofetil in Patients With Inherited Disorders

Metabolism, Inborn Errors | Granulomatous Disease, Chronic

United States
Kemin Foods LC
DSM Nutritional Products, Inc.

Terminated

Effects of Lutein on Visual Function

Healthy | Nutrition Poor

United Kingdom
Thomas S. Scanlan

Withdrawn

Safety and Pharmacodynamic Study of Sobetirome in X-Linked Adrenoleukodystrophy (X-ALD)

Adrenomyeloneuropathy | X-Linked Adrenoleukodystrophy

United States

Clinical Trials on Metabolic Syndrome X in United Kingdom

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