Clinical Trials on Metabolic Syndrome X in United Kingdom

Total 34853 results

Stanford University

Completed

Effects of Social Gaze Training on Brain and Behavior in Fragile X Syndrome

Intellectual Disability | Fragile X Syndrome

United States
Novartis Pharmaceuticals

Completed

A Randomized, Double-blind, Placebo Controlled Study to Assess Efficacy, Safety and Tolerability of LCQ908 in Subjects With Familial Chylomicronemia Syndrome

Familial Chylomicronemia Syndrome (FCS)

South Africa, Spain, France, Germany, United Kingdom, United States, Canada, Netherlands
Fred Hutchinson Cancer Center

Completed

Study of Total Body Irradiation and Fludarabine Followed By Allogeneic Peripheral Blood Stem Cell or Bone Marrow Transplantation in Combination With Cyclosporine and Mycophenolate Mofetil in Patients With Inherited Disorders

Metabolism, Inborn Errors | Granulomatous Disease, Chronic

United States
Mitsubishi Tanabe Pharma America Inc.

Recruiting

INcreased Sun Exposure Without Pain In Research Participants With EPP or XLP (INSPIRE)

Erythropoietic Protoporphyria (EPP) | X-Linked Protoporphyria (XLP)

United States, Spain, France, Japan, United Kingdom, Italy, Australia, Poland, Bulgaria, Czechia, Netherlands
Hoffmann-La Roche

Completed

A Study With RO4917523 in Patients With Fragile X Syndrome

Fragile X Syndrome

United States
Seaside Therapeutics, Inc.

Suspended

A Study to Assess the Tolerability of a Single Dose of STX107 in Adults With Fragile X Syndrome

Fragile X Syndrome

United States
National Human Genome Research Institute (NHGRI)

Completed

Genetic Analysis of Oculocerebrorenal Syndrome of Lowe

Lowe Syndrome

United States
Promethera Therapeutics

Completed

Safety Study of HepaStem for the Treatment of Urea Cycle Disorders (UCD) and Crigler-Najjar Syndrome (CN) (HEP001)

Urea Cycle Disorders | Crigler Najjar Syndrome

Israel, United Kingdom, Belgium, France, Italy
REGENXBIO Inc.

Active, not recruiting

CAMPSIITE™ RGX-121 Gene Therapy in Subjects With MPS II (Hunter Syndrome)

Mucopolysaccharidosis Type II (MPS II)

United States, Brazil
King's College Hospital NHS Trust

Terminated

Pilot Study of Reduced Intensity Haematopoietic Stem Cell Transplantation in Patients With Poor Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukaemia (AML) Utilising Conditioning With Fludarabine, Busulphan and Thymoglobulin (FB-ATG)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

United Kingdom
UK Kidney Association

Recruiting

National Registry of Rare Kidney Diseases (RaDaR)

Vasculitis | AL Amyloidosis | Tuberous Sclerosis | Fabry Disease | Cystinuria | Focal Segmental Glomerulosclerosis | IgA Nephropathy | Bartter Syndrome | Pure Red Cell Aplasia | Membranous Nephropathy | Atypical Hemolytic Uremic Syndrome | Autosomal Dominant Polycystic Kidney Disease | Cystinosis | Nephronophthisis | BK Nephropathy and other conditions

United Kingdom
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Pharmacokinetics (PK) and Pharmacodynamics (PD) of Mayne Glucagon for Injection Compared With Glucagen® (Novo Nordisk) in Healthy Volunteers

Hypoglycemia

United Kingdom
Ultragenyx Pharmaceutical Inc

Terminated

Crossover Study to Assess the Efficacy and Safety of UX007 in the Treatment of Movement Disorders Associated With Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS)

Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS)

United States, Spain, France, Germany, Italy, United Kingdom
NeuroVia, Inc.

Unknown

A Study to Prospectively Assess Disease Progression in Male Children With X-ALD

X-Linked Adrenoleukodystrophy

United States
Vanderbilt University Medical Center
International Tree Nut Council Research and Education Foundation

Completed

Tree Nut Consumption to Reduce Abdominal Adiposity

Millenials | Risk for Metabolic Syndrome

United States
Ultragenyx Pharmaceutical Inc

Completed

Phase 2 Study of Triheptanoin (UX007) for the Treatment of Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS)

Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS)

United States, Spain, Australia, France, Israel, Italy, United Kingdom
Sangamo Therapeutics

Enrolling by invitation

Long-Term Follow-up of Subjects Who Were Treated With ST-920

Fabry Disease | Fabry Disease, Cardiac Variant

United States, Australia, United Kingdom
Zealand Pharma

Enrolling by invitation

Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS - Extension Trial (EASE SBS 3)

Short Bowel Syndrome

Germany, United States, Belgium, Denmark, France, United Kingdom, Netherlands, Poland
UCB BIOSCIENCES, Inc.

Recruiting

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet Syndrome (ORCHID)

Dravet Syndrome

United States, United Kingdom
Children's Hospital Medical Center, Cincinnati
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Alpha Auditory Entrainment for Cognitive Enhancement and Sensory Hypersensitivity in Youth With Developmental Disorders (ENTRAIN)

Autism Spectrum Disorder | Autistic Disorder | Fragile X Syndrome | Asperger Syndrome

United States
Amsterdam UMC, location VUmc
Boehringer Ingelheim; Abbott

Unknown

MEDICLAS Study (Metabolic Effects of Different Classes of AntiretroviralS)

HIV Infections | HIV-Associated Lipodystrophy Syndrome

Finland, Netherlands, Spain, United Kingdom
GlaxoSmithKline

Completed

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GSK3915393 in Healthy Participants and to Evaluate the Interaction Between GSK3915393 and Grapefruit Juice and Itraconazole

Celiac Disease | Coeliac Disease

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Case Finding for Coeliac Disease Using a Point of Care Test in a Pharmacy Setting

Coeliac Disease

United Kingdom
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Safety and Efficacy of PRX-102 in Patients With Fabry Disease Currently Treated With REPLAGAL® (Agalsidase Alfa)

Fabry Disease

Australia, Netherlands, United Kingdom, Canada, Czechia, Norway, Slovenia
University Hospital Birmingham NHS Foundation Trust
Northern Care Alliance NHS Foundation Trust; Cambridge University Hospitals... and other collaborators

Active, not recruiting

Arrhythmia Burden, Risk of Sudden Cardiac Death and Stroke in Patients With Fabry Disease (RaILRoAD)

Fabry Disease

United Kingdom, Australia
Dr. Schär AG / SPA

Completed

Market Research - Acceptability Trial for a New PKU Amino Acid Based Protein Substitute

Phenylketonurias | Inborn Errors of Metabolism | Metabolic Disease | PKU

United Kingdom
NorthSea Therapeutics B.V.

Completed

A Study to Evaluate the Effects of NST-4016 on QT/Corrected QT (QTc) Interval

Dyslipidemias

United Kingdom
Kathryn Beardsall

Completed

Point of Care Ketone Measurement in the Newborn (POCKET)

Hypoglycaemia

United Kingdom
Mitsubishi Tanabe Pharma Corporation

Completed

Evaluation of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TA-8995 With Single, Escalating Doses in Healthy Subjects

Dyslipidemia

United Kingdom
NHS Greater Glasgow and Clyde
University of Glasgow

Not yet recruiting

Adiposity and Immunometabolism in Sepsis (AIMS)

Sepsis | Obesity

United Kingdom
University of Edinburgh
Novartis; NHS Lothian

Active, not recruiting

Muscle Wasting in Cancer (MWIC) (MWIC)

Cachexia

United Kingdom
Tetra Discovery Partners

Recruiting

A Study of BPN14770 in Male Adults (Aged 18 to 45) With Fragile X Syndrome

Fragile X Syndrome

United States
Novartis Pharmaceuticals

Completed

Study for the Treatment of Transfusional Iron Overload in Myelodysplastic Patients

Myelodysplastic Syndromes | Iron Overload

United States
CENTOGENE GmbH Rostock

Completed

The Efficacy and Safety of Switch Between Agalsidase Beta to Agalsidase Alfa for Enzyme Replacement in Patients With Anderson-Fabry Disease (SWITCH)

Fabry Disease | Anderson-Fabry Disease | Fabry´s Disease

Argentina, Belgium, Croatia, Czechia, Denmark, France, Germany, United Kingdom
Seaside Therapeutics, Inc.

Terminated

An Open Label Extension Study of STX209 in Subjects With Fragile X Syndrome

Fragile X Syndrome

United States
University of Roehampton

Terminated

In Vivo Effects of the Gluten Friendly Bread in Coeliac Disease

Celiac Disease

United Kingdom
Alcobra Ltd.

Completed

A 6-week, Study of MG01CI Low Dose and High Dose Compared With Placebo in Adults and Adolescents With Fragile X Syndrome

Fragile X Syndrome

United States, Israel
Freeline Therapeutics

Terminated

A Fabry Disease Gene Therapy Study (MARVEL1)

Lysosomal Storage Diseases | Fabry Disease

United States, Norway, Germany, Austria, United Kingdom, Italy, Canada
Abliva AB

Completed

A Phase Ia/Ib, SAD and MAD Study of of KL1333 in Healthy Subjects and Patients With Primary Mitochondrial Disease

Mitochondrial Diseases | Mitochondrial Myopathies | MELAS Syndrome | Mitochondrial Respiratory Chain Deficiencies

United Kingdom
University of Leeds

Completed

Effects of Polyphenols Found in Pomegranate Juice on Postprandial Blood Glucose in Vivo

Hyperglycaemia

United Kingdom
Xention Ltd

Completed

ADME Study in Healthy Male Subjects With TA-8995

Dyslipidemia

United Kingdom
University College, London
Barts & The London NHS Trust

Unknown

Coronary Mortality in South Asians: Aetiologic and Prognostic Effects (CALIBER)

Acute Coronary Syndromes

United Kingdom
Astellas Gene Therapies

Completed

A Clinical Assessment Study in X-Linked Myotubular Myopathy (XLMTM) Subjects (INCEPTUS)

X-linked Myotubular Myopathy

United States, France, United Kingdom, Canada, Germany
Vital Signs Solutions Ltd

Recruiting

PocDoc Lipids Out-of-Surgery Study

Dyslipidemias

United Kingdom
University of Alabama, Tuscaloosa
McCormick Science Institute

Recruiting

Spices for Cultivating a Healthy Gut Microbiome and Cardiometabolic Profile

Cardiometabolic Syndrome

United States
Elizabeth Berry-Kravis
National Institute of Neurological Disorders and Stroke (NINDS); Novartis Pharmaceuticals

Completed

AFQ056 for Language Learning in Children With FXS (FX-LEARN)

Fragile X Syndrome

United States
Loughborough University
University of Bedfordshire

Completed

Is Mid-morning Breakfast as Healthy as Early-morning Breakfast for Blood Sugar Control in Adolescent Girls?

Postprandial Hyperglycemia

United Kingdom
Manchester University NHS Foundation Trust

Completed

Effect of Tredaptive on Serum Lipoproteins and Inflammatory Markers

Hypercholesterolemia

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Unknown

Can Contrast Enhanced Spectral Mammography (CESM) Reduce the Number of Benign Biopsies for Calcifications Without Negatively Impacting on Detection/Diagnosis of Clinically Significant Calcifications (MICROENHANCE)

Mammography

United Kingdom
University College, London

Completed

SS-INQ Information Needs Questionnaire in Sjögren's Syndrome (SS-INQ)

Sjögren's Syndrome

United Kingdom

Clinical Trials on Metabolic Syndrome X in United Kingdom

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