Clinical Trials on Metastatic Malignant Neoplasm in the Brain

Total 2420 results

Giselle Sholler
Translational Genomics Research Institute; Dell, Inc.

Completed

Molecular-Guided Therapy for Childhood Cancer

Glioma | Renal Cell Carcinoma | Osteosarcoma | Ependymoma | Medulloblastoma | Neuroblastoma | Meningioma | Craniopharyngioma | Choroid Plexus Neoplasms | Rhabdomyosarcoma | Wilms Tumor | Ewings Sarcoma | Malignant Rhabdoid Tumor | Liver Tumors | Germ Cell Tumors | Dysembryoplastic Neuroepithelial Tumor | Clear Cell Sarcoma | ... and other conditions

United States, Lebanon
Mayo Clinic
National Institute on Aging (NIA); Minnesota HealthSolutions

Recruiting

A Study of Caregiver Connections Via Technology in Dementia

Dementia | Alzheimer Disease | Frontotemporal Dementia | Lewy Body Dementia | Parkinson Disease Dementia | Caregiver Stress

United States
Mayo Clinic
National Institute on Aging (NIA); Minnesota HealthSolutions

Withdrawn

A Study to Evaluate Caregiver Connections Via Technology for Patients With Alzheimer's and Other Types of Dementia

Dementia | Frontotemporal Dementia | Alzheimer Dementia | Lewy Body Dementia | Parkinson Disease Dementia | Caregiver Stress
Centre Hospitalier Universitaire Dijon

Unknown

COVID-19 Related Lockdown Effects On Chronic Diseases (CLEO-CD)

Heart Failure | Multiple Sclerosis | Hemophilia | Chronic Respiratory Failure | Horton's Disease | Chronic Coronary Syndrome | AMD and Macular Edema | Malignant Hemopathy

France
Istituto Auxologico Italiano

Recruiting

Efficacy of Split Gait in the Treatment of Dynamic Asymmetries in Subjects With Pathologic Claudication (ESPLICA)

Multiple Sclerosis | Parkinson Disease | Amputation | Poststroke/CVA Hemiparesis | Knee Impairment

Italy
Institute for Neurodegenerative Disorders

Terminated

Evaluation of [18F] PBR06 and PET as a Marker of Inflammation in Subjects With Neurological Conditions (PBR06)

Multiple Sclerosis | Parkinson Disease | Alzheimer Disease

United States
Amsterdam UMC, location VUmc
GGZ inGeest; Parnassia Bavo Groep

Terminated

Online Cognitive Training in PD, MS and Depressed Patients Treated With Electroconvulsive Therapy

Multiple Sclerosis | Idiopathic Parkinson's Disease | Elderly Post Electric Convulsive Therapy

Netherlands
National Cancer Institute (NCI)

Completed

Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Childhood Brain Stem Glioma | Recurrent Childhood Visual Pathway Glioma | Childhood Central Nervous System Germ Cell Tumor | Childhood Central Nervous System Choriocarcinoma | Childhood Central... and other conditions

United States
Frantz Viral Therapeutics, LLC
University of California, San Francisco; Laser Surgery Care; Amarex CRO; Anal Dysplasia...

Active, not recruiting

Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL (anal HSIL HIV-)

HPV Infection | Anal Dysplasia | Anal High Grade Squamous Intraepithelial Lesion | Anal Precancerous Condition | AIN 2/3 | HPV Disease

United States
National Cancer Institute (NCI)

Recruiting

Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Multiple Sclerosis | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Psoriasis | Systemic Scleroderma | Crohn Disease | Ulcerative Colitis | Dermatomyositis | Psoriatic Arthritis | Inflammatory Bowel Disease | Autoimmune Disease | Sjogren...

United States, Canada
Centre de Recherche de l'Institut Universitaire...
Canadian Institutes of Health Research (CIHR)

Completed

Evaluation of a Cognitive Psychophysiological Treatment for Tourette Syndrome and Tic Disorders

Tourette Syndrome | Tourette Syndrome in Children | Tic Disorder, Chronic Motor or Vocal

Canada
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Completed

High-dose ICE With Amifostine

Sarcoma | Kidney Cancer | Testicular Germ Cell Tumor | Head and Neck Cancer | Ovarian Cancer | Lung Cancer | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Bladder Cancer | Extragonadal Germ Cell Tumor | Carcinoma of Unknown Primary

United States
Novartis Pharmaceuticals

Completed

Yttrium Y 90 SMT 487 in Treating Patients With Refractory or Recurrent Cancer

Lymphoma | Breast Cancer | Lung Cancer | Brain and Central Nervous System Tumors | Melanoma (Skin) | Islet Cell Tumor | Gastrointestinal Carcinoid Tumor | Neoplastic Syndrome

United States
Amgen

Completed

Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium

Lymphoma | Kidney Cancer | Breast Cancer | Head and Neck Cancer | Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Non-Small Cell Lung Cancer | Lung Cancer | Metastatic Cancer | Colon Cancer | Thyroid Cancer | Renal Cancer | Parathyroid Neoplasms | Endocrine Cancer | Hypercalcemia of Malignancy

United States, Italy, France, Canada, Poland
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors

Sarcoma | Glioblastoma | Recurrent Ovarian Carcinoma | Recurrent Uterine Corpus Carcinoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Metastatic Renal Cell Cancer | Recurrent Lung Carcinoma | Recurrent Renal Cell Carcinoma | Stage IV Skin Melanoma | Recurrent Melanoma | Stage IIIB Skin Melanoma | Stage... and other conditions

United States
University of Chicago

Not yet recruiting

Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues

Multiple Sclerosis | Obesity | Obesity, Morbid | Obese | Long COVID | Long Covid19 | Acute Leukemia in Remission
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus

Acquired Immunodeficiency Syndrome | BK Virus Infection | Merkel Cell Carcinoma | Human Immunodeficiency Virus | Malignant Neoplasm | JC Virus Infection | Merkel Cell Polyomavirus Infection | Viral Encephalitis

United States
National Cancer Institute (NCI)

Recruiting

National Cancer Institute "Cancer Moonshot Biobank"

Malignant Solid Neoplasm | Acute Myeloid Leukemia | Multiple Myeloma | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer... and other conditions

United States, Puerto Rico
Istituto Auxologico Italiano
IRCCS Istituto Neurologico Carlo Besta

Recruiting

Gait and Balance Impairment in Rare and Very Rare Neurological Diseases (GALVANISE)

Multiple Sclerosis | Healthy | Parkinson Disease | Healthy Aging | Peripheral Neuropathy | Rare Diseases

Italy
Yale University

Recruiting

Intestinal Immunity in Neurologic Disease

Multiple Sclerosis | Parkinson Disease | REM Sleep Behavior Disorder

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer

Cervical Intraepithelial Neoplasia | Cervical Adenocarcinoma | Cervical Squamous Cell Carcinoma, Not Otherwise Specified | Vaginal Adenocarcinoma | Vulvar Intraepithelial Neoplasia | Stage I Cervical Cancer AJCC v8 | Stage IA Cervical Cancer AJCC v8 | Stage IA1 Cervical Cancer AJCC v8 | Stage IA2 Cervical... and other conditions

United States
ConvaTec Inc.
ClinSearch

Withdrawn

GentleCath Air (Urinary Self-catheterization) - Pain in Female Patients With Neurological Vesico-sphincter Disorders (FollowAir)

Multiple Sclerosis | Parkinsonian Disorders | Spinal Cord Injuries | Allodynia
Accelerated Cure Project for Multiple Sclerosis

Active, not recruiting

Biobank For MS And Other Demyelinating Diseases

Multiple Sclerosis | Optic Neuritis | Neuromyelitis Optica | Transverse Myelitis | Acute Disseminated Encephalomyelitis

United States
University of Texas Southwestern Medical Center

Completed

PEDIATRIC SONICS: Pediatric Study of Neuropsychology and Imaging in CNS Demyelinating Syndromes. (SONICS)

Multiple Sclerosis, Relapsing-Remitting | Neuromyelitis Optica | Transverse Myelitis | Acute Disseminated Encephalomyelitis

United States
University of Exeter
GaitQ company

Recruiting

Smart Wearable Device (gaitQ): Walk Better Project

Stroke | Multiple Sclerosis | Arthritis | Parkinson Disease | Osteoporosis

United Kingdom
Rajavithi Hospital
Rajavithi Biomolecular Research Center

Withdrawn

Rajavtihi Neuronal Adult Stem Cells Project (RNASc)

Multiple Sclerosis | Parkinson's Disease | Alzheimer's Disease

Thailand
Institute for Neurodegenerative Disorders

Terminated

Evaluation of [123I]CLINDE and SPECT as a Marker of Inflammation in Subjects With PD or AD and in Healthy Subjects (CLINDE)

Multiple Sclerosis | Parkinson Disease | Alzheimer Disease | Healthy Controls

United States
Institute for Neurodegenerative Disorders

Completed

Evaluation of [18F] FEPPA and PET Imaging as a Marker of Inflammation in Subjects With Neurological Conditions

Multiple Sclerosis | Parkinson Disease | Alzheimer Disease

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Cyclophosphamide and Busulfan Followed by Donor Stem Cell Transplant in Treating Patients With Myelofibrosis, Acute Myeloid Leukemia, or Myelodysplastic Syndrome

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia... and other conditions

United States
Wayne State University
Blue Cross Blue Shield of Michigan Foundation

Unknown

Timing of Acute Palliative Care Consultation in Critically Ill Patients

Multiple Sclerosis | Sepsis | Hepatic Encephalopathy | Parkinson's Disease | Dementia | Multiple Organ Failure | Chronic Kidney Disease Stage 5 | Solid Organ Cancer | End Stage Chronic Obstructive Airways Disease | In-Hospital Cardiac Arrest | End Stage Cardiac Failure

United States
Memorial Sloan Kettering Cancer Center

Completed

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

Sarcoma | Small Intestine Cancer | Ovarian Cancer | Lung Cancer | Brain and Central Nervous System Tumors | Metastatic Cancer | Neuroblastoma | Intraocular Melanoma | Melanoma (Skin) | Retinoblastoma

United States
University Rovira i Virgili
Ministerio de Ciencia e Innovación, Spain

Recruiting

Dementias and Microbiota Composition: Is Possible to Revert the Dementia Symptoms Reverting the Microbiota Composition? (DEM-BIOTA)

Mild Cognitive Impairment | Dementia With Lewy Bodies | Dementia Alzheimers | Parkinson Disease Dementia | Dementia Frontotemporal

Spain
National Institute of Neurological Disorders and...

Recruiting

Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Amyotrophic Lateral Sclerosis | Frontotemporal Dementia | Progressive Supranuclear Palsy

United States
Ontario Neurodegeneration Disease Research Initiative

Completed

The Ontario Neurodegenerative Disease Research Initiative (ONDRI)

Stroke | Parkinson Disease | Amyotrophic Lateral Sclerosis | Alzheimer Disease | Frontotemporal Dementia

Canada
University of California, San Francisco
University of Colorado, Denver; National Institute on Aging (NIA); HealthPartners... and other collaborators

Recruiting

The Care Ecosystem Consortium Effectiveness Study

Dementia | Frontotemporal Dementia | Dementia, Vascular | Dementia With Lewy Bodies | Dementia Alzheimers

United States
Washington University School of Medicine
Association of Frontotemporal Degeneration; Tau Consortium

Completed

Human CNS Tau Kinetics in Tauopathies (TANGLES)

Progressive Supranuclear Palsy (PSP) | Corticobasal Degeneration (CBD) | Frontotemporal Dementia (FTD MAPT Mutation)

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors

Advanced Malignant Solid Neoplasm | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Advanced Pancreatic Adenocarcinoma | Platinum-Resistant... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Terminated

TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients With Metastatic, Persistent, Recurrent, or Progressive Solid Tumors

Recurrent Renal Cell Carcinoma | Stage IV Skin Melanoma | Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer | Metastatic Pancreatic Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage IV Breast Cancer | Recurrent Breast Carcinoma | Recurrent Colorectal Carcinoma | Colorectal... and other conditions

United States
Cedars-Sinai Medical Center
National Cancer Institute (NCI)

Recruiting

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

Gastrointestinal Neoplasms | Stomach Cancer | Small Intestine Cancer | Rectal Cancer | Neuroendocrine Tumor | Bile Duct Cancer | Colon Cancer | Pancreas Cancer | Anal Cancer | Liver Cancer | Biliary Tract Cancer | Peritoneal Cancer | Carcinoid Tumor | Gallbladder Cancer | Cancer Pain | Carcinoid Tumor of the Small Bowel | Visceral... and other conditions

United States
National Cancer Institute (NCI)
Celgene Corporation

Active, not recruiting

Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction

Glioma | Hematopoietic and Lymphoid Cell Neoplasm | Lymphoma | Recurrent Head and Neck Carcinoma | Recurrent Lung Carcinoma | Recurrent Renal Cell Carcinoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Recurrent Pancreatic Carcinoma | Stage III Pancreatic Cancer... and other conditions

United States, Canada
Arkansas Colleges of Health Education

Recruiting

High Intensity Functional Training for Individuals With Neurologic Diagnoses and Their Care Partners (SHIFT-AR)

Stroke | Multiple Sclerosis | Brain Injuries | Parkinson Disease | Spinal Cord Injuries | Neurologic Disorder | Poliomyelitis | Spina Bifida

United States
National Cancer Institute (NCI)

Withdrawn

Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunction

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Stage IV Non-Small Cell Lung Cancer | Metastatic Pancreatic Adenocarcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast... and other conditions
National Cancer Institute (NCI)

Completed

Cixutumumab, Everolimus, and Octreotide Acetate in Treating Patients With Advanced Low to Intermediate Grade Neuroendocrine Carcinoma

Lung Carcinoid Tumor | Metastatic Digestive System Neuroendocrine Tumor G1 | Paraganglioma | Pancreatic Polypeptide Tumor | Pancreatic Glucagonoma | Pancreatic Insulinoma | Recurrent Merkel Cell Carcinoma | Somatostatin-Producing Neuroendocrine Tumor | Stage IV Merkel Cell Carcinoma | Recurrent Digestive... and other conditions

United States
IRCCS Centro Neurolesi "Bonino-Pulejo"

Completed

The Efficacy of VESPA 2.0 for Cognitive Rehabilitation in Patients With Mild Cognitive Impairment

Multiple Sclerosis | Neurodegenerative Diseases | Alzheimer Disease | Cognitive Decline | Parkinson Disease Dementia

Italy
Göteborg University
The Swedish Research Council; Swedish Council for Working Life and Social Research

Completed

Finding the Right Words in Neurogenic Communication Disorders

Stroke | Multiple Sclerosis | Parkinson Disease | Aphasia | Anomia

Sweden
IRCCS San Camillo, Venezia, Italy
IRCCS Centro San Giovanni di Dio Fatebenefratelli; Università Ca' Foscari Venezia

Recruiting

Exploring the Gut-Brain Axis in Ageing and Neurodegeneration (GutBrain)

Multiple Sclerosis | Healthy | Parkinson Disease | Prodromal Alzheimer's Disease

Italy
Wake Forest University Health Sciences

Withdrawn

Establishment of a Human Tissue Bank for Studying the Microbial Etiology of Neurodegenerative Diseases

Multiple Sclerosis | Parkinson Disease | Neurodegenerative Diseases | Amyotrophic Lateral Sclerosis

United States
Tempus AI

Recruiting

Tempus Priority Study: A Pan-tumor Observational Study

Lymphoma | Leukemia | Breast Cancer | Pancreatic Cancer | Ovarian Cancer | Fallopian Tube Cancer | Lung Cancer | Prostate Cancer | Brain Cancer | Bladder Cancer | Cancer of Head and Neck | Peritoneal Cancer | Cancer of Liver | Cancer of Stomach | Cancer of Cervix | Cancer of Colon | Cancer of Rectum | Cancer of Gastrointestinal... and other conditions

United States
University of Pennsylvania
Thomas Jefferson University; Drexel University

Active, not recruiting

Care of Persons With Dementia in Their Environments (COPE) in Programs of All-Inclusive Care of the Elderly (PACE)

Neurocognitive Disorders | Dementia | Alzheimer Disease | Lewy Body Disease | Frontotemporal Dementia | Vascular Dementia | Mixed Dementia | Pick Disease | Multi-Infarct Dementia

United States
University College, London
The University of Hong Kong

Active, not recruiting

Virtual Individual Cognitive Stimulation Therapy: a Proof of Concept Study (V-iCST)

Dementia | Dementia, Vascular | Dementia, Mixed | Dementia With Lewy Bodies | Dementia Alzheimers | Dementia of Alzheimer Type | Dementia, Multi-Infarct | Dementia, Mild | Dementia Moderate | Dementia Frontal | Dementia Frontotemporal

United Kingdom

Clinical Trials on Metastatic Malignant Neoplasm in the Brain

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Rwanda

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations