Clinical Trials on Metastatic Pancreatic Cancer in Spain

Total 3039 results

Spanish Cooperative Group for the Treatment of...
Amgen

Completed

Safety and Efficacy Study of Panitumumab+Irinotecan in Patients Wild-Type (WT) KRAS Metastatic Colorectal Cancer Refractory to Irinotecan Based Chemotherapy (SPECTRA) (SPECTRA)

Metastatic Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Merck Sharp & Dohme LLC

Terminated

Phase II Study to Evaluate Safety and Efficacy of Cetuximab in Combination With XELOX for 12 Weeks Followed by Maintenance Treatment With Cetuximab Plus Capecitabine as First-line Treatment in Elderly Patients With Metastatic Colorectal Cancer.

Metastatic Colorectal Cancer

Spain
Associacio catalana per a la recerca oncologica...
Amgen

Unknown

A Clinical Trial of Panitumumab in Combination With FOLFIRI Chemotherapy as Second Line Treatment in Subjects With Metastatic Colorectal Cancer Expressing Wild-type KRAS and Who Had Progressed ≥ 6 Months After the Last Dose of the First Line Chemotherapy (ACTIVE)

Metastatic Colorectal Cancer

Spain
Novartis Pharmaceuticals

Completed

A Phase Ib/II Study of BEZ235 and Trastuzumab in Patients With HER2-positive Breast Cancer Who Failed Prior to Trastuzumab

Metastatic Breast Cancer (MBC) | Locally Advance Breast Cancer (LABC)

United Kingdom, Spain
Genentech, Inc.

Active, not recruiting

Safety and Pharmacokinetics (PK) of Escalating Doses of Tiragolumab as a Single Agent and in Combination With Atezolizumab and/or Other Anti-Cancer Therapies in Locally Advanced or Metastatic Tumors

Advanced/Metastatic Tumors

Spain, United States, Korea, Republic of, Australia, France, Japan, Canada
Spanish Cooperative Group for the Treatment of...
Sanofi

Completed

Study to Assess the Efficacy and Safety of Treatment With FOLFIRI-aflibercept Compared to Initial Treatment With FOLFIRI-aflibercept (for 6 Cycles) Followed by Maintenance With 5FU-aflibercept, in an Elderly Population With mCRC After Failure of an Oxaliplatin-based Regimen (AFEMA)

Metastatic Colorectal Cancer

Spain
Spanish Cooperative Group for the Treatment of...
Hoffmann-La Roche

Completed

Irinotecan, Capecitabine and Bevacizumab in Metastatic Colorectal Cancer Patients (AVAXIRI)

Metastatic Colorectal Cancer

Spain
Unidad Integral de Investigación en Oncología S.L.
Hoffmann-La Roche

Completed

1stline Study Capecitabine Administered on Continuous Way Plus Oxaliplatin&Bevacizumab Every 2weeks in Metastatic CCR.

Metastatic Colorectal Cancer

Spain
Modra Pharmaceuticals

Completed

ModraDoc006/r in Patients With Breast Cancer

Metastatic Breast Cancer | Recurrent Breast Cancer

Denmark, Belgium, Spain
Spanish Cooperative Group for the Treatment of...
Roche Pharma AG

Completed

Influence of BRAF and PIK3K Status on the Efficacy of 5-Fluorouracil/Leucovorin/Oxaliplatin (FOLFIRI) Plus Bevacizumab or Cetuximab in Patients With RAS Wild-type Metastatic Colorectal Carcinoma and < 3 Circulating Tumor Cells (CTC) (VISNU-2)

Colorectal Cancer Metastatic

Spain
AstraZeneca
Merck Sharp & Dohme LLC; Myriad Genetic Laboratories, Inc.

Completed

Olaparib in gBRCA Mutated Pancreatic Cancer Whose Disease Has Not Progressed on First Line Platinum-Based Chemotherapy (POLO)

Metastatic Adenocarcinoma of the Pancreas | Germline BRCA1/2 Mutations and

United States, France, Italy, Spain, United Kingdom, Belgium, Canada, Germany, Korea, Republic of, Australia, Israel, Netherlands
Grupo Espanol de Tumores Neuroendocrinos

Completed

A Trial to Assess the Activity and Safety of Palbociclib in Patients With Well and Moderately Differentiated Metastatic Pancreatic Neuroendocrine Tumors (pNET) (PALBONET)

Pancreatic Neuroendocrine Cancer

Spain
Novartis Pharmaceuticals

Completed

Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors

Metastatic Colorectal Cancer | Gastric Cancer | Advanced Solid Tumors | Metastatic Breast Cancer | Gastroesophageal Junction Cancer | Recurrent Glioblastoma Multiforme | Advanced Pancreatic Adenocarcinoma | Safety | Triple Negative Metastatic Breast Cancer | Dose Escalation | Preliminary Efficacy | Hormone Receptor...

Canada, United Kingdom, Spain, Germany, Italy, Belgium, Australia, United States
Bayer

Completed

RE-SEARCH Study: A Study to Learn How and in Which Amount Regorafenib is Given in Usual Practice to Patients in Spain: a Study Looking Back at Cases That Have Already Happened When the Study Begins. (RE-SEARCH)

Metastatic Colorectal Cancer

Spain
Cancer Trials Ireland

Terminated

Copanlisib in Combination With T-DM1 in Pretreated Unresectable Locally Advanced or Metastatic HER2-positive Breast Cancer (Panthera)

Metastatic Breast Cancer | HER2-positive Breast Cancer | Locally Advanced Breast Cancer | Unresectable Breast Cancer

Ireland, Spain
Sanofi
BioNTech RNA Pharmaceuticals GmbH

Terminated

A First-in-Human Dose Escalation and Expansion Study to Evaluate Intratumoral Administration of SAR441000 as Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Metastatic Neoplasm

France, Spain, United States, Belgium, Germany, Netherlands
Hospital Galdakao-Usansolo

Completed

Cost Effectiveness of an Intervention in Hospitalized Patients With Disease-related Malnutrition

Inflammatory Bowel Diseases | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Crohn Disease | Ulcerative Colitis | Pancreatitis, Acute | Esophagus Cancer

Spain
Akamis Bio

Completed

Phase I / II Study of Enadenotucirev by Sub-acute Fractionated IV Dosing in Cancer Patients (EVOLVE)

Metastatic Colorectal Cancer | Metastatic Bladder Cancer | Solid Tumours of Epithelial Origin

Belgium, Spain
Celgene

Completed

Observational Study of Quality of Live in Patients With Metastatic Pancreatic Cancer (aLIVE)

Pancreatic Neoplasms

Spain
OncoSil Medical Limited

Recruiting

FOLFIRINOX Versus OncoSil™ in Addition to FOLFIRINOX in Patients With Locally Advanced Pancreatic Adenocarcinoma (TRIPP-FFX)

Locally Advanced Pancreatic Cancer

Spain, Belgium, United Kingdom, Italy, Australia
Neovii Biotech

Terminated

Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer Progressing After Endocrine Treatment

Advanced Breast Cancer | Metastatic Breast Cancer

Spain, Austria, France, Germany, Italy
SOLTI Breast Cancer Research Group

Recruiting

Predicting Olaparib Sensitivity in Patients With Unresectable Locally Advanced/Metastatic HER2-negative Breast Cancer. (RADIOLA)

Metastatic Breast Cancer | Triple Negative Breast Cancer | HER2-negative Breast Cancer

Spain
Amgen
Roche-Genentech

Completed

Study of Talimogene Laherparepvec With Atezolizumab for Triple Negative Breast Cancer and Colorectal Cancer With Liver Metastases

Metastatic Colorectal Cancer | Metastatic Triple Negative Breast Cancer

United States, Belgium, Spain, Australia, Switzerland, Germany
Spanish Cooperative Group for the Treatment of...
Roche Pharma AG

Completed

Study of 5-Fluorouracil/Leucovorin/Oxaliplatin (FOLFOX) + Bevacizumab Versus 5-Fluorouracil/Leucovorin/Oxaliplatin/Irinotecan (FOLFOXIRI) + Bevacizumab as First Line Treatment of Patients With Metastatic Colorectal Cancer Not Previously Treated and With Three or More Circulating Tumoral Cells (VISNU-1)

Metastatic Colorectal Cancer

Spain
Novartis Pharmaceuticals

Terminated

Study of Safety and Efficacy of Ribociclib and Trametinib in Patients With Metastatic or Advanced Solid Tumors

Solid Tumors for Phase Ib | Pancreatic Cancer for Phase II | Colorectal Cancer for Phase II

United States, Canada, Australia, Belgium, Germany, Netherlands, Spain
Eisai Farmacêutica S.A.

Completed

Eribulin [Halaven] Use For the Treatment of Advanced Breast Cancer (EUFORIA-1)

Metastatic Breast Cancer

Spain
Centro Nacional de Investigaciones Oncologicas...
Apices Soluciones S.L.; Hospital Universitario de Fuenlabrada; Grupo Hospital...

Completed

Study of Individualized Selection of Chemotherapy in Patients With Advanced Pancreatic Carcinoma According to Therapeutic Targets

Advanced Pancreatic Carcinoma

Spain
Bristol-Myers Squibb

Completed

A Study of Cabiralizumab Given With Nivolumab With and Without Chemotherapy in Patients With Advanced Pancreatic Cancer

Advanced Pancreatic Cancer

United States, Canada, Germany, United Kingdom, Taiwan, Italy, Korea, Republic of, Switzerland, Denmark, Japan, Spain
SOLTI Breast Cancer Research Group
Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab + Paclitaxel in Hormone Receptor-positive (HR+)/Human Epidermal Growth Factor Receptor 2-negative (HER2-) Non-luminal (by PAM50) Advanced Breast Cancer After Cyclin-dependent Kinase 4/6 (CDK4/6) Inhibitors Progression (TATEN)

Metastatic Breast Cancer

Spain
Incyte Biosciences International Sàrl

Completed

A Phase 1/2, Open-Label, Dose-Escalation, Safety Study of INCAGN01949 in Subjects With Advanced or Metastatic Solid Tumors

Metastatic Cancer | Advanced Malignancies

United States, United Kingdom, Spain, Switzerland
Hospital Clinico Universitario de Santiago

Recruiting

Registry of Pancreatic Exocrine Insufficiency.

Exocrine Pancreatic Insufficiency

Spain
Novartis Pharmaceuticals

Terminated

Study of Efficacy and Safety of NIS793 (With and Without Spartalizumab) in Combination With SOC Chemotherapy in First-line Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC) (daNIS-1)

Metastatic Pancreatic Ductal Adenocarcinoma

Belgium, Finland, Taiwan, Australia, Germany, Spain, Italy, Austria, Czechia, Switzerland, Singapore, United Kingdom, United States, France
SOLTI Breast Cancer Research Group
Roche Pharma AG

Recruiting

Ipatasertib + Pertuzumab +Trastuzumab in Advanced HER2+ PI3KCA-mutant Breast Cancer Patients (IPATHER)

Metastatic Breast Cancer

Spain
Hospital Miguel Servet
Aragon Health Science Institute

Completed

Use of Hemopatch as a Sealant at the Pancreaticojejunostomy After Pancreatoduodenectomy

Pancreatic Fistula

Spain
Alligator Bioscience AB
Theradex; 4Pharma Ltd.

Recruiting

Safety and Efficacy of Mitazalimab in Combination With Chemotherapy in Pancreatic Cancer Patients (OPTIMIZE-1)

Metastatic Pancreatic Ductal Adenocarcinoma

France, Belgium, Spain
Ignacio Puche Sanz
Chinese University of Hong Kong; UMC Utrecht; University of Padova; Medical University... and other collaborators

Not yet recruiting

BAseLine TEstosterone as a Prognostic and/or Predictive bioMARKer in mHSPC

Prostate Cancer Metastatic

Spain
PIQUR Therapeutics AG
Hospital Universitari Vall d'Hebron Research Institute; Institut Català d'Oncologia and other collaborators

Completed

PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)

Metastatic Breast Cancer

Spain, United Kingdom
Spanish Breast Cancer Research Group
Roche Farma, S.A

Completed

Evaluation of Hypertension as a Predictor of Efficacy Bevacizumab in Metastatic Breast Cancer and Colorectal Cancer (BRECOL)

Metastatic Colorectal Cancer | Metastatic Breast Cancer

Spain
Fundación de Investigación Biomédica - Hospital...

Completed

Contrast Enhanced Ultrasound and Molecular Analysis in the Diagnosis of Pancreatic Cyst

Pancreatic Cyst

Spain
Spanish Cooperative Group for the Treatment of...
Bayer

Terminated

Regorafenib as Single Agent in Patients With Metastatic Colorectal Cancer (mCRC) With Any RAS or BRAF Mutation Previously Treated With FOLFOXIRI Plus Bevacizumab (PREVIUM)

Colorectal Neoplasms | Metastatic Disease

Spain
Spanish Cooperative Group for the Treatment of...
Bayer

Completed

Regorafenib in Frail and/or Unfit for Chemotherapy Patients With Metastatic Colorectal Cancer (REFRAME)

Colorectal Neoplasms | Metastatic Disease

Spain
Hospital Clinico Universitario de Santiago

Recruiting

Impact of Pancreatic Endoscopic Drainage on Exocrine Pancreatic Function in Unresectable Pancreatic Cancer (DEPARA)

Pancreatic Exocrine Insufficiency | Pancreatic Neoplasm Malignant Head Primary

Spain
SOLTI Breast Cancer Research Group
Merck Sharp & Dohme LLC; Pfizer; AstraZeneca; Astellas Pharma Inc; Advanced Accelerator... and other collaborators

Recruiting

Feasibility and Impact of Liquid Biopsy Genomic Profiling on Treatment Patients With Metastatic Prostate Cancer in Spain (SOLTI-2102) (HOPE-PROSTATE)

Metastatic Prostate Cancer

Spain
Pharmacyclics LLC.

Completed

Study of Ibrutinib vs Placebo, in Combination With Nab-paclitaxel and Gemcitabine, in the First Line Treatment of Patients With Metastatic Pancreatic Adenocarcinoma (RESOLVE)

Metastatic Pancreatic Adenocarcinoma

Spain, Italy, Korea, Republic of, United States, Belgium, United Kingdom, Germany, France
Spanish Breast Cancer Research Group
Bristol-Myers Squibb

Completed

Dasatinib In Combination With Trastuzumab And Paclitaxel In First Line Treatment Of Her2-Positive MBC Patients

Metastatic Breast Cancer

Spain
Bayer

Active, not recruiting

A Real-World Study to Learn More About the Order of Different Treatments and Their Effects in People With Metastatic Colorectal Cancer Receiving Their Third and Fourth Line of Treatment (RegoSeq)

Metastatic Colorectal Cancer

Spain, Italy, France
Centro Nacional de Investigaciones Oncologicas...
Fundacion CRIS de Investigación para Vencer el Cáncer

Completed

Abrogation of Chronic Monoclonal Antibody Treatment-induced T-cell Exhaustion With DURVALUMAB in Advanced HER-2 Negative Breast Cancer

Metastatic Breast Cancer | Bevacizumab-alone Maintenance Treatment Progression

Spain
Hospital del Río Hortega
Complejo Hospitalario de Navarra; Clinica Universidad de Navarra, Universidad... and other collaborators

Completed

Nasobiliary Drain Assisted EUS-guided Gastroenterostomies in Unresectable Malignant Gastric Outlet Obstruction (PENGUIN)

Gastric Cancer | Pancreatic Cancer | Gastric Outlet Obstruction

Spain, India
Jules Bordet Institute
Breast International Group

Completed

BIG Molecular Screening Feasibility Study (BIG MS Pilot)

Metastatic Breast Cancer

Belgium, Spain, Germany, United Kingdom
Fundació Institut de Recerca de l'Hospital de la...

Unknown

Micrometastases and Angiogenesis in Colon Cancer. Prognostic Value of VEGF. (VEGF-GC)

Colorectal Cancer | Angiogenesis

Spain

Clinical Trials on Metastatic Pancreatic Cancer in Spain

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