Clinical Trials on Metastatic Disease

Total 382670 results

University of Arizona

Terminated

Vertebral Augmentation and Radiotherapy of Collapse Spinal Metastatic Cancer

Multiple Myeloma | Vertebral Fracture | Metastatic Cancers

United States
Ascendo Biotechnology Co., Ltd.

Not yet recruiting

Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ASD141

Metastatic Solid Tumor
Ectin Research AB

Not yet recruiting

A Study of MFA-370 in Patients With Metastatic Urothelial Cancer (MANHATTAN)

Metastatic Urothelial Cancer

Sweden
Merck KGaA, Darmstadt, Germany

Completed

Phase I/Ib Multiple Ascending Dose Study in China

Metastatic Solid Tumors

China
Matthew Galsky
Icahn School of Medicine at Mount Sinai; AstraZeneca

Completed

Trial of Olaparib in Patients With Metastatic Urothelial Cancer Harboring DNA Damage Response Gene Alterations

Metastatic Urothelial Cancer

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Trial for Salvage Re-Irradiation of Metastatic Spine Lesions Using Single-Fraction Stereotactic Radiosurgery

Metastatic Spine Lesions

United States
Institut Bergonié
Bayer

Completed

A Retrospective Study to Determine the Incidence of NTRK Fusions. NTRK Study (NTRK)

Metastatic Solid Tumors

France
University Hospital, Ghent

Completed

Trial of Stereotactic Body Radiotherapy With Concurrent Pembrolizumab in Metastatic Urothelial Cancer

Metastatic Urothelial Cancer

Belgium
Beth Israel Deaconess Medical Center
Amgen

Completed

Mini Allo Stem Cell Transplantation for the Treatment of Solid Tumors (MiniSolid)

Metastatic Solid Tumor

United States
University Health Network, Toronto

Recruiting

In Vivo Lung Perfusion (IVLP) for Colorectal Cancer Metastatic to Lung

Colorectal Cancer | Lung Metastases | Colorectal Cancer Metastatic

Canada
Menoufia University

Recruiting

A Study Evaluating Maintenance Therapy After First Line Chemotherapy in Metastatic Cancer Pancreas

Cancer of Pancreas

Egypt
The Christie NHS Foundation Trust

Not yet recruiting

Irinotecan Drug-eluting Bead Liver Embolisation Registry (DLivERDEBIRI)

Colorectal Cancer Metastatic | Liver Metastases

United Kingdom
Dorte Nielsen

Completed

Intra-hepatic Chemotherapy in Patients With Liver Metastases From Breast Cancer and Limited Extrahepatic Disease

Metastatic Breast Cancer | Liver Metastases

Denmark
Dorte Nielsen

Completed

Intra-hepatic Chemotherapy in Patient With Non-resectable Liver Metastases From Breast Cancer

Metastatic Breast Cancer | Liver Metastases

Denmark
WntResearch AB

Completed

Dose Escalating Study of Foxy-5 in Breast-, Colon- or Prostate Cancer Patients

Metastatic Breast Cancer | Metastatic Prostate Cancer | Metastatic Colon Cancer

Denmark, United Kingdom
Xingchen Peng

Recruiting

Early Nutrition Intervention for M1 Stage Cancer Patients

Nutrition | Cancer Metastatic

China
University Medical Center Groningen

Recruiting

IL-2 PET Imaging in Advanced Solid Tumours

Metastatic Solid Tumor

Netherlands
University Medical Center Groningen
Regeneron Pharmaceuticals

Active, not recruiting

LAG3 PET Imaging in Advanced Solid Tumors

Metastatic Solid Tumor

Netherlands
University Medical Center Groningen

Terminated

Side Effects of Vascular Endothelial Growth Factor (VEGF) and Epidermal Growth Factor Receptor (EGFR) Directed Therapy (Mabtornib)

Metastatic Malignancies

Netherlands
University of Liege
Fondation Benoit

Withdrawn

Study of the Impact of Non-pharmacological Techniques on Cognitive Complaints in Cancer Patients

Non-Metastatic Neoplasm

Belgium
Kimberly Blackwell

Terminated

Intrathecal Pertuzumab and Trastuzumab in Patients With New Untreated Asymptomatic or Low Symptomatic Brain Metastasis in HER2 Positive Breast Cancer

HER2 Positive Untreated Metastatic Breast Cancer | Asymptomatic or Low Symptomatic Brain Metastasis in Breast Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Antiandrogen Therapy With or Without Axitinib Before Surgery in Treating Patients With Previously Untreated Prostate Cancer With Known or Suspected Lymph Node Metastasis

Metastatic Malignant Neoplasm in Lymph Node | Prostate Ductal Adenocarcinoma | Stage III Prostate Adenocarcinoma AJCC v7 | Stage IV Prostate Adenocarcinoma AJCC v7

United States
Central European Society for Anticancer Drug Research

Completed

FOLFIRI and Sunitinib in Metastatic Colorectal Cancer

Metastatic Colorectal Cancer | Liver Metastases

Germany
Institut Curie

Completed

Validity of HER2-amplified Circulating Tumor Cells to Select Metastatic Breast Cancer Considered HER2-negative for Trastuzumab-emtansine (T-DM1) Treatment.

Metastatic Breast Cancer, HER2 Negative Primary Tumor

France
Hoffmann-La Roche

Completed

A Study of Bevacizumab (Avastin) in Combination With Chemotherapy in Participants With Metastatic Cancer of the Colon or Rectum

Colorectal Cancer

Taiwan
Hoffmann-La Roche

Completed

OBELIX Study: A Study of Avastin (Bevacizumab) in Combination With XELOX in Patients With Metastatic Cancer of the Colon or Rectum.

Colorectal Cancer

Italy
Nanobiotix

Recruiting

NBTXR3 Activated by Radiotherapy for Patients With Advanced Cancers Treated With An Anti-PD-1 Therapy

Metastatic Renal Cell Carcinoma | Squamous Cell Carcinoma of Head and Neck | Radiotherapy | Immunotherapy | Microsatellite Instability-High Solid Malignant Tumour | Metastasis From Malignant Tumor of Liver | Metastasis From Malignant Tumor of Cervix | Metastasis From Malignant Melanoma of Skin (Disorder) and other conditions

United States
Mayo Clinic

Completed

A Vaccine (PolyPEPI1018 Vaccine) and TAS-102 for the Treatment of Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Metastatic... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Brain

United States
HUYABIO International, LLC.
Bristol-Myers Squibb

Recruiting

Study Comparing Investigational Drug HBI-8000 Combined With Nivolumab vs. Nivolumab in Patients With Advanced Melanoma

Unresectable or Metastatic Melanoma | Progressive Brain Metastasis

Spain, United States, Italy, Japan, Belgium, France, New Zealand, Brazil, Korea, Republic of, Australia, Germany, Singapore, Czechia, Austria, South Africa, United Kingdom, Puerto Rico
University of Washington
National Cancer Institute (NCI)

Completed

Liposomal Cytarabine and High-Dose Methotrexate in Treating Patients With Central Nervous System Metastases From Breast Cancer

Stage IV Breast Cancer | Leptomeningeal Metastases | Recurrent Breast Cancer | Central Nervous System Metastases | Tumors Metastatic to Brain

United States
Dartmouth-Hitchcock Medical Center

Withdrawn

Genetically-informed Therapies for Patients With Metastatic Cancer (GENIUS)

Metastatic Cancer

United States
Eli Lilly and Company

Completed

A Phase 3 Trial of ALIMTA (LY231514, Pemetrexed) Plus GEMZAR Versus GEMZAR in Patients With Unresectable or Metastatic Cancer of the Pancreas.

Pancreatic Neoplasms | Metastases, Neoplasm

United States, France, United Kingdom, Germany, Taiwan, Spain, Belgium, Portugal, Peru, Austria, Italy, Sweden, Netherlands, Venezuela, Argentina, Australia, Colombia, Greece
Melanoma and Skin Cancer Trials Limited
University of Oxford; Trans Tasman Radiation Oncology Group

Active, not recruiting

Whole Brain Radiotherapy Following Local Treatment of Intracranial Metastases of Melanoma (WBRTMel)

Metastatic Melanoma

Norway, Australia, United Kingdom
Centre Hospitalier Universitaire de Nīmes

Completed

Circulating Tumor Cells and Melanoma: Comparing the EPISPOT and CellSearch Techniques

Metastatic Melanoma

France
Hoffmann-La Roche

Completed

A Study of Bevacizumab (Avastin) in Combination With Chemotherapy in Participants With Metastatic Cancer of the Colon or Rectum.

Colorectal Cancer

Brazil
Hoffmann-La Roche

Completed

An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Cancer of the Colon or Rectum

Colorectal Cancer

Montenegro
Mirati Therapeutics Inc.

Recruiting

Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)

Metastatic Cancer | Advanced Cancer | Malignant Neoplasm of Lung

Spain, United States, Turkey, Korea, Republic of, Brazil, Croatia, France, Greece, Israel, Italy, Mexico, Netherlands, Poland, Romania, Serbia, Taiwan, Thailand
Prof. Wolfgang Janni

Completed

DETECT III - A Multicenter, Phase III Study to Compare Standard Therapy +/- Lapatinib in HER2-ve MBC-Patients With HER2+ve CTCs (DETECT III)

HER2-negative Metastatic Breast Cancer | HER2-positive Circulating Tumor Cells

Germany
Imunon

Completed

A Study of ThermoDox™ in Combination With Radiofrequency Ablation (RFA) in Primary and Metastatic Tumors of the Liver

Liver Neoplasms | Hepatocellular Carcinoma

United States
Fudan University

Unknown

Expression of Molecular Markers in Circulating Tumor Cells of Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer Metastatic

China
Immune Design

Terminated

Phase 1b Safety Study of CMB305 in Patients With Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1

Melanoma | Sarcoma | Ovarian Cancer | Non-small Cell Lung Cancer

United States
Azienda Ospedaliera di Padova

Unknown

Pilot Study of Irreversible Electroporation (IRE) to Treat Metastatic Liver Cancer & Cholangiocarcinoma

Neoplasm Metastasis | Cholangiocarcinoma | Metastatic Liver Cancer

Italy
Chongqing Precision Biotech Co., Ltd

Recruiting

Clinical Study of CD70-targeted CAR-T Therapy for Advanced/Advanced Renal Cancer

Renal Cell Carcinoma | Advanced Cancer | Metastatic Tumor

China
Acepodia Biotech, Inc.

Recruiting

ACE1702 in Subjects With Advanced or Metastatic HER2-expressing Solid Tumors

Solid Tumor | Metastatic Cancer | HER2-positive Gastric Cancer | HER2-positive Metastatic Breast Cancer | Locally Advanced Solid Tumor

United States, Taiwan
Mohammed M Milhem
Genentech, Inc.

Terminated

Treatment of a Resistant Disease Using Decitabine Combined With Vemurafenib Plus Cobimetinib (ML28604)

Melanoma | Metastatic Melanoma | BRAF-mutated Metastatic Melanoma | V600EBRAF-mutated Metastatic Melanoma

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Metastatic Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Melanoma (Skin)

United States
Rigshospitalet, Denmark

Not yet recruiting

Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study (PPGL-Pred)

Head and Neck Cancer | Genetic Predisposition to Disease | Neuroendocrine Tumors | Pheochromocytoma | Paraganglioma | Pathology | Somatic Mutation

Denmark
Alpha Tau Medical LTD.

Terminated

Alpha Radiation Emitters Device for the Treatment of Newly Diagnosed Breast Carcinoma Patients With Distant Metastases

Metastatic Breast Cancer | Breast Carcinoma | Invasive Breast Cancer | Distant Metastases.Pathology

Russian Federation
Shanghai Miracogen Inc.

Recruiting

A Study of MRG002 in Patients With HER2-Positive Advanced Solid Tumors and Locally Advanced or Metastatic Gastric/Gastroesophageal Junction (GEJ) Cancer

Advanced Solid Tumors | Advanced or Metastatic Gastric Cancer | Advanced or Metastatic Gastroesophageal Junction Cancer

United States

Clinical Trials on Metastatic Disease

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