Clinical Trials on Metastatic Endocrine Tumors/ Neuroendocrine Tumors

Total 17701 results

National Cancer Institute (NCI)

Recruiting

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

Solid Tumor | Refractory Solid Tumors | Malignant Solid Tumors | Other Neoplasms Solid Tumors | Pediatric Solid Tumor

United States
University of Southern California
National Cancer Institute (NCI)

Completed

Regorafenib in Treating Patients With Advanced or Metastatic Neuroendocrine Tumors

Gastrinoma | Glucagonoma | Insulinoma | Metastatic Gastrointestinal Carcinoid Tumor | Pancreatic Polypeptide Tumor | Recurrent Gastrointestinal Carcinoid Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma | Pulmonary Carcinoid Tumor

United States
University of Wisconsin, Madison

Completed

A Biological Study of Resveratrol's Effects on Notch-1 Signaling in Subjects With Low Grade Gastrointestinal Tumors

Neuroendocrine Tumor

United States
University Hospital, Basel, Switzerland
University Hospital, Zürich; University Hospital Freiburg; Krebsforschung Schweiz... and other collaborators

Recruiting

177Lu-PP-F11N for Receptor Targeted Therapy and Imaging of Metastatic Thyroid Cancer. (Lumed)

Thyroid Cancer, Medullary | Neuroendocrine Tumor of the Lung Grade 1 and 2 | Neuroendocrine Tumor of the Thymus Grade 1 and 2 | Neuroendocrine Tumor GEP Grade 1-3

Switzerland
Changhai Hospital

Completed

Real-world Study on Adjuvant Octreotide Therapy in pNETs

Pancreatic Neuroendocrine Tumor G2
HaEmek Medical Center, Israel

Unknown

Safety and Efficacy of an Ablation Catheter for the Treatment of Pancreatic Premalignant Cyctic Lesions. (yes)

Pancreatic Cancer | Pancreatic Cyst | Pancreatic Neuroendocrine Tumor | Pancreatic Cancer Stage
Massachusetts General Hospital

Withdrawn

A Pilot Study Of Ga-68-DOTA-TOC Imaging In Participants With Small Bowel Carcinoid Tumors

Small Bowel Carcinoid Tumor

United States
Asan Medical Center
Novartis

Unknown

Clinical Effectiveness of Serum Chromogranin A Levels on Diagnostic of Pancreatic Neuroendocrine Tumors (CgA)

Non Functioning Pancreatic Endocrine Tumor
University of Chicago

Not yet recruiting

Study Comparing Standard of Care Chemotherapy With/ Without Sequential Cytoreductive Surgery for Patients With Metastatic Foregut Cancer and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid Levels

Lung Cancer | Gastric Adenocarcinoma | Metastatic Cancer | Liver Cancer | GI Cancer | Foregut Carcinoid Tumor | Gallbladder Adenocarcinoma | GI Carcinoma
Dana-Farber Cancer Institute
Eli Lilly and Company

Active, not recruiting

A Phase II Study of Ramucirumab With Somatostatin Analog Therapy in Patients With Advanced, Progressive Carcinoid Tumors

Carcinoid Tumors

United States
H. Lee Moffitt Cancer Center and Research Institute
Novartis Pharmaceuticals; RECORDATI GROUP

Completed

Study of Pasireotide Long Acting Release (LAR) in Patients With Metastatic Neuroendocrine Tumors (NETs)

Neuroendocrine Tumors | Carcinoid Tumors

United States
University of Western Ontario, Canada

Terminated

Effect of Oral 5-HTP Intake on Urinary 5-HIAA Excretion

Neuroendocrine Tumors | Carcinoid Tumors

Canada
GERCOR - Multidisciplinary Oncology Cooperative...
Pfizer; Ipsen

Unknown

A Study of Sunitinib Versus Placebo in Combination With Lanreotide in Patients With Progressive Advanced/Metastatic Midgut Carcinoid Tumors (SUNLAND)

Carcinoid Tumors

France, Belgium
Rambam Health Care Campus

Completed

SPECT/CT in Endocrine and Neuroendocrine Tumors

Endocrine and Neuroendocrine Tumors

Israel
Amgen

Completed

Open Label Extension Study of Conatumumab and Ganitumab (AMG 479)

Sarcoma | Lymphoma | Colorectal Cancer | Non-Small Cell Lung Cancer | Advanced Solid Tumors | Metastatic Cancer | Solid Tumors | Carcinoid | Locally Advanced

United States, Spain, Poland
National Cancer Institute (NCI)

Terminated

Romidepsin in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors

Gastrinoma | Glucagonoma | Insulinoma | Metastatic Gastrointestinal Carcinoid Tumor | Pancreatic Polypeptide Tumor | Recurrent Gastrointestinal Carcinoid Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma | Regional Gastrointestinal Carcinoid Tumor | Pulmonary Carcinoid Tumor

United States
Tianjin Medical University Cancer Institute and...

Recruiting

Multi-cohort Study of Surufatinib Plus Sintilimab in Metastatic NEN and Pancreatic Carcinoma Who Failed Standard Chemotherapy

Pancreatic Carcinoma | Neuroendocrine Carcinoma | Neuroendocrine Tumor Grade 3

China
Gustave Roussy, Cancer Campus, Grand Paris
National Cancer Institute, France; Advanced Accelerator Applications

Recruiting

Antitumor Efficacy of Peptide Receptor Radionuclide Therapy With 177Lutetium -Octreotate Randomized vs Sunitinib in Unresectable Progressive Well-differentiated Neuroendocrine Pancreatic Tumor: First Randomized Phase II (OCCLURANDOM)

Pancreatic Neuroendocrine Carcinoma

France
Novartis Pharmaceuticals

Completed

Safety/Efficacy of Everolimus in Adults With Advanced Pancreatic Neuroendocrine Cancer Not Responsive to Chemotherapy

Pancreatic Neoplasms | Neuroendocrine Tumor | Neuroendocrine Carcinoma | Islet Cell Carcinoma

United States, Canada, Spain, Argentina, Germany, Belgium, Italy, France, Sweden, Australia, Netherlands
M.D. Anderson Cancer Center

Active, not recruiting

Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic Melanoma

Melanoma | Metastatic Melanoma | Tumor

United States
Institut Bergonié
French Sarcoma Group

Active, not recruiting

Patterns of Care and Outcomes in Patients With Metastatic Bone Tumors (METABONE) (METABONE)

Metastatic Bone Tumor

France
Catholic University of the Sacred Heart

Completed

Endoscopic Ultrasound-guided RadioFrequency Ablation for the Treatment Pancreatic NeuroEndocrine Neoplasms (RAPNEN)

Neuroendocrine Tumors | Neuroendocrine Carcinoma | Pancreas Neoplasm | Neuroendocrine Tumor Gastrointestinal, Hormone-Secreting

Italy
GlaxoSmithKline

Completed

Study of Dabrafenib +/- Trametinib in Combination With Ipilimumab for V600E/K Mutation Positive Metastatic or Unresectable Melanoma

Solid Tumours

United States
Ipsen

Completed

Quality-Of-Life QLQ-GINET21 Questionnaire In The Treatment Of Patients With Gastrointestinal Neuroendocrine Tumours (QUALINETS)

Gastrointestinal Neuroendocrine Tumours

Spain, Portugal
Ipsen

Completed

Quality of Life, Treatment Experience and Cost of Treatment With Somatostatin Analogues in Patients With Gastroenteropancreatic Neuroendocrine Tumours (STREET)

Gastroenteropancreatic Neuroendocrine Tumours

Sweden
National Cancer Institute (NCI)
National Institutes of Health Clinical Center (CC)

Terminated

T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Melanoma

Metastatic Cancer | Metastatic Melanoma

United States
Lale Kostakoglu

Terminated

68Ga-Dotatoc Positron Emission Tomography (PET) for Somatostatin Receptor-Positive Neuroendocrine Tumors (NETs)

Neuroendocrine Tumors | Carcinoid Tumors

United States
National Cancer Institute (NCI)

Not yet recruiting

Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy

Pheochromocytoma | Somatostatin Receptor Positive | Paragangliomas | Gastrointestinal Neuroendocrine Tumors

United States
Novartis Pharmaceuticals

Completed

Safety and Tolerability of Pasireotide LAR in Combination With Everolimus in Advanced Metastatic NETs (COOPERATE-1)

Gastroenteropancreatic Neuroendocrine Tumor of the Pulmonary ot Gastroenteropancreatic System

Germany
Ipsen

Completed

Somatuline Predictive Factors in Acromegaly and NET (SOPRANo)

Acromegaly | Neuroendocrine Tumours

Switzerland, Austria, Germany
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Recruiting

A Trial Aiming to Assess the Safety and Activity of the Combination of Cabozantinib Plus Lanreotide in GEP and NET (LOLA)

Neuroendocrine Tumors | Metastatic Well Differentiated Neuroendocrine Neoplasm

Italy
O'Dorisio, M S
National Cancer Institute (NCI)

Completed

Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid Tumors

Sarcoma | Unspecified Childhood Solid Tumor, Protocol Specific | Brain and Central Nervous System Tumors | Neuroblastoma | Pheochromocytoma | Islet Cell Tumor | Gastrointestinal Carcinoid Tumor

United States
Genentech, Inc.

Active, not recruiting

Safety and Pharmacokinetics (PK) of Escalating Doses of Tiragolumab as a Single Agent and in Combination With Atezolizumab and/or Other Anti-Cancer Therapies in Locally Advanced or Metastatic Tumors

Advanced/Metastatic Tumors

Spain, United States, Korea, Republic of, Australia, France, Japan, Canada
University of Maryland, Baltimore
Novartis

Withdrawn

Pasireotide Treatment for Neuroendocrine Tumor

Gastro-enteropancreatic Neuroendocrine Tumor
CHU de Reims

Unknown

Interest of Whole-body MRI Correlated to Spreading Sequences for Staging Neuroendocrine Tumors (LAB-2013-01)

Neuroendocrine Tumors With Metastasis
University Hospital, Montpellier

Not yet recruiting

Identification and Characterization of Circulating Tumor Cells Before and After Treatment (Surgery and Radiotherapy) in a Cohort of Patients Treated for Resectable Stage I-III Merkel Cell Carcinoma (MERCCALIBI)

Merkel Cell Carcinoma
GlaxoSmithKline

Completed

Japan PhI/II of GSK2118436 and GSK1120212 Combination in Subjects With BRAF V600E/K Mutation Positive Advanced Solid Tumors (Phase I Part) or Cutaneous Melanoma (Phase II Part)

Solid Tumours

Japan
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Prophylactic Cholecystectomy is Not Mandatory in Patients Candidate to the Resection for Small Intestine Neuroendocrine Neoplasms: a Propensity Score-matched and Cost-minimization Analysis

Surgery | Neuroendocrine Tumors | Gut Tumor
Sue O'Dorisio

Completed

Safety of 68Ga-DOTA-tyr3-Octreotide PET in Diagnosis of Solid Tumors (GA-68)

Neuroendocrine Tumors | Medulloblastoma | Neuroblastoma | Carcinoid Tumors

United States
M.D. Anderson Cancer Center
TerSera Therapeutics LLC

Recruiting

Telotristat Ethyl for the Treatment of Carcinoid Heart Disease in Patients With Metastatic Neuroendocrine Tumor

Locally Advanced Neuroendocrine Neoplasm | Metastatic Neuroendocrine Neoplasm

United States
Abramson Cancer Center of the University of Pennsylvania

Withdrawn

Bio-marker Analysis Using Circulating Tumor Cells in Patients With Melanoma

Melanoma
Centre Hospitalier Universitaire de Nice

Completed

Study of Circulating Tumor Cells Before and After Treatment in Patients With Metastatic Melanoma

Melanoma

France
National Cancer Institute (NCI)

Completed

Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Ovarian Carcinoma | Pancreatic Neuroendocrine Tumor | Unresectable Solid Neoplasm | Fibrolamellar Carcinoma

United States
Grupo Espanol de Tumores Neuroendocrinos
Roche Pharma AG; Ipsen

Active, not recruiting

Trial of Cabozantinib Plus Atezolizumab in Advanced and Progressive Neoplasms of the Endocrine System. The CABATEN Study (CABATEN)

Adenocarcinoma | Neuroendocrine Tumor | Pheochromocytoma | Paraganglioma | Anaplastic Thyroid Cancer

Spain
Sichuan Huiyang Life Science and Technology Corporation
Medelis Inc.

Active, not recruiting

Study of rSIFN-co for Patients With Advanced Solid Tumors

Malignancies Including Melanoma, Kidney, Lung, Colorectal, Prostate, Neuroendocrine Tumor

United States
University of California, San Francisco
Sanofi; Genentech, Inc.

Terminated

Combination Chemotherapy and Bevacizumab in Treating Patients With Advanced Neuroendocrine Tumors

Lung Cancer | Neuroendocrine Tumor | Islet Cell Tumor | Gastrointestinal Carcinoid Tumor | Neoplastic Syndrome

United States
Zagazig University

Completed

Side-specific Factors for Conversion in Adrenalectomy for Pheochromocytoma.

Adrenal Tumor
University of Alabama at Birmingham

Withdrawn

Molecular-Guided Surgery for Pancreatic and GI Neuroendocrine Cancers

Carcinoid | Neuroendocrine Carcinoma of Pancreas

United States
University of Sao Paulo
Instituto do Cancer do Estado de São Paulo

Recruiting

Stereotactic Body Radiation Therapy (SBRT) for Unresectable Liver Metastases

Colorectal Cancer | Liver Metastases | Anal Canal Cancer | Gastrointestinal Neuroendocrine Tumors

Brazil
Sue O'Dorisio
National Cancer Institute (NCI)

Completed

Comparative Study of Sensitivity of Ga-DOTATOC PET vs Octreoscan SPECT + CT

Neuroendocrine Tumor | Neuroblastoma | Somatostatinoma | Adult Medulloblastoma | Childhood Medulloblastoma

United States

Clinical Trials on Metastatic Endocrine Tumors/ Neuroendocrine Tumors

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