Clinical Trials on Metastatic Head-and-neck Squamous-cell Carcinoma

Total 19234 results

Peter MacCallum Cancer Centre, Australia
Sanofi; Regeneron Pharmaceuticals; Monash University; University of Adelaide; University...

Recruiting

Deep sequencIng in Cutaneous Squamous CEll caRciNomas (DISCERN)

Neoplasms | Cutaneous Squamous Cell Carcinoma of the Head and Neck | Non-melanoma Skin Cancer | Cutaneous Squamous Cell Carcinoma

Australia
China Medical University Hospital

Completed

Biweekly TPF Induction Chemotherapy for Locally Advanced Squamous Cell Carcinoma of Head and Neck

Locally Advanced Head and Neck Carcinoma
Washington University School of Medicine

Completed

Determine Tumor Response Using Fluorodeoxyglucose (FDG)- Positron Emission Tomography (PET)/Computed Tomography (CT) Before and After Cetuximab in Patients With Head and Neck Cancer (SCCHN)

Carcinoma, Squamous Cell

United States
Boehringer Ingelheim

Terminated

Dose Escalation of Bivatuzumab Mertansine in Patients With Advanced Squamous Cell Carcinoma of the Head and Neck or Esophagus

Carcinoma, Squamous Cell
University of Southern California
National Cancer Institute (NCI)

Recruiting

FID-007 Followed by Standard of Care Surgery in Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma

United States
Yonsei University

Not yet recruiting

Trial of Neoadjuvant Therapy With Paclitaxel and Carboplatin in Operable Locally Advanced Head and Neck Cancer Patients (NEOS)

Head and Neck Squamous Cell Carcinoma

Korea, Republic of
Technical University of Munich

Recruiting

Liquid Biopsy of Head and Neck Cancer Patients in Blood and Saliva (KOHACIN)

Head and Neck Squamous Cell Carcinoma

Germany
University of Texas Southwestern Medical Center
National Cancer Institute (NCI)

Recruiting

A Phase 2a, Single-dose, Open-label Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer, in Patients With Unknown Primary Head and Neck Cancer (ILLUMINATE STUDY)

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Unknown Primary Cancer

United States
Rennes University Hospital

Completed

One-step Nucleic Acid Amplification for Detecting Lymph Node Metastasis of Head and Neck Squamous Cell Carcinoma (OSNA-ORL)

cN0 Oral Squamous Cell Carcinomas

France
Lai-ping Zhong
Sun Yat-sen University; Fudan University; Fujian Medical University; Central South...

Recruiting

Neoadjuvant Immunochemotherapy for LAOSCC

Oral Squamous Cell Carcinoma | Locally Advanced Head and Neck Carcinoma

China
Rakuten Medical, Inc.

Withdrawn

RM-1995 Photoimmunotherapy, as Monotherapy or Combined With Pembrolizumab, in Patients With Advanced CuSCC and HNSCC

Head and Neck Squamous Cell Carcinoma | Cutaneous Squamous Cell Carcinoma

United States
University Medical Center Groningen

Recruiting

Real-time Margin Assessment in Head and Neck Cancer (LIGHTNING)

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma

Netherlands
Yonsei University
Genexine, Inc.; NeoImmuneTech

Recruiting

Trial of the Combination of GX-188E Vaccination, GX-I7 and Pembrolizumab in Patients With Advanced, Resectable HPV Type 16 and/or 18 Positive Head and Neck Cancer (GENUINE)

Head and Neck Squamous Cell Carcinoma

Korea, Republic of
Luzerner Kantonsspital
Universität Luzern

Recruiting

Do Markers of Systemic Inflammatory Response and Tumor Metabolism Indicate Radioresistance in Head and Neck Cancer?

Head and Neck Squamous Cell Carcinoma

Switzerland
West Virginia University

Recruiting

A Comparison of NETSPOT Imaging Versus F-FDG-PET in Head and Neck Cancer Patients

Head and Neck Squamous Cell Carcinoma

United States
University of California, San Francisco
Incyte Corporation

Completed

Ruxolitinib in Operable Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma

United States
Jules Bordet Institute

Active, not recruiting

Prospective Pilot Study Evaluating Dental Side Effects of Radiotherapy on Subjects Treated for Head and Neck Cancer (StomRay)

Head and Neck Squamous Cell Carcinoma

Belgium
PharmaEngine

Terminated

A Study of PEP503 With Radiotherapy in Combination With Concurrent Chemotherapy for Patients With Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma

Taiwan
University of Chicago

Terminated

Epacadostat and Pembrolizumab in Patients With Head and Neck Cancer That Have Failed Prior Immunotherapy (ORKA)

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma

United States
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Completed

An Experimental Study to Compare Treatment Response and Toxicities of Concurrent Chemoradiation With Weekly Cisplatin and Three Weekly Cisplatin in Locally Advanced Head and Neck Cancer. (HNC)

Head and Neck Squamous Cell Carcinoma

Bangladesh
University of Michigan Rogel Cancer Center

Completed

Benefits of Exercise Training in Head and Neck Cancer Patients Undergoing Organ-Preserving Definitive Therapy

Head and Neck Squamous Cell Carcinoma

United States
Institut de cancérologie Strasbourg Europe
Hôpitaux Universitaires de Strasbourg

Recruiting

Optimisation of Potential Dental Implant Sites Protection for Rehabilitation in Patients With Head and Neck Cancer: Impact of Virtual Implants Visualisation on Dosimetry (OPPIDOM) (OPPIDOM)

Squamous Cell Carcinoma of Head and Neck | Oropharyngeal Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma

France
Jewish General Hospital
McGill University Health Centre/Research Institute of the McGill University...

Recruiting

Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck

Sentinel Lymph Node | Cutaneous Squamous Cell Carcinoma

Canada
Shanghai Jiao Tong University School of Medicine

Completed

Carrimycin in Patients With Locally Advanced, Recurrent, or Metastatic HNSCC (Non NPC): A Phase I Trial

Head and Neck Squamous Cell Carcinoma | Oral Squamous Cell Carcinoma

China
Shi Yuankai

Recruiting

Study of Pembrolizumab Combined With Anlotinib in the First Line Therapy for R/M HNSCC With CPS≥1

Head and Neck Squamous Cell Carcinoma

China
Sun Yat-sen University
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Neoadjuvant Camrelizumab in Combination With Cisplatin and Nab-paclitaxel in Resectable HNSCC

Head and Neck Squamous Cell Carcinoma

China
Xinqiao Hospital of Chongqing
TCRCure Biopharma Ltd.

Recruiting

EBV-Specific Anti-PD1 TCR-T Cells in the Treatment of EBV-Positive NHSCC

Head and Neck Squamous Cell Carcinoma

China
Groupe Oncologie Radiotherapie Tete et Cou

Active, not recruiting

Stereotactic Radiotherapy Combined With Chemotherapy or Not for Treatment of Oligometastases in HNSCC (OMET)

Head and Neck Squamous Cell Carcinoma

France
Sanofi
Groupe Oncologie Radiotherapie Tete et Cou

Completed

TRACE: Tirapazamine-Radiation And Cisplatin Evaluation (TRACE)

Head and Neck Squamous Cell Carcinoma

United States, France, Canada, Poland, Germany, Spain, Switzerland, Singapore, Taiwan, Argentina, Hungary, Italy, Chile, Hong Kong, South Africa, Australia, New Zealand
Centre Leon Berard
The Biostatistics and Therapy Evaluation Unit

Completed

Protocole Advanced RadioTherapy ORL (ART-ORL)

Head and Neck Squamous Cell Carcinoma

France
Ipsen

Terminated

Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1.

Gastric Cancer | Colorectal Cancer | Bone Cancer | Squamous Cell Carcinoma of the Head and Neck | Advanced Cancer | Recurrent Disease | Pancreatic Ductal Adenocarcinoma | Metastatic Tumours

United States, France, Belgium, Switzerland, Netherlands
University of California, Davis

Completed

Use of a Non-ICU Specialty Ward For Immediate Post-operative Management of Head and Neck Free Flaps (ICU)

Head and Neck Cancer | Trauma | Head and Neck Squamous Cell Carcinoma | Head and Neck Carcinoma

United States
Andrei Iagaru
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Panitumumab-IRDye800 and 89Zr-Panitumumab in Identifying Metastatic Lymph Nodes in Patients With Squamous Cell Head and Neck Cancer

Squamous Cell Carcinoma of the Head and Neck | Carcinoma of the Head and Neck

United States
University of Wisconsin, Madison
National Cancer Institute (NCI)

Recruiting

Pilot Study of Imatinib Cetuximab Combo for H & N Cancer

Head and Neck Cancer | Squamous Cell Carcinoma of Head and Neck

United States
The Netherlands Cancer Institute

Completed

ctDNA as a Biomarker for Treatment Response in HNSCC (PECAN)

Carcinoma, Squamous Cell of Head and Neck

Netherlands
Washington University School of Medicine
Pfizer

Completed

PD 0332991 and Cetuximab in Patients With Incurable SCCHN

Carcinoma, Squamous Cell of Head and Neck

United States
The Netherlands Cancer Institute
Merck KGaA, Darmstadt, Germany

Completed

Bioimmunoradiotherapy (Cetuximab/RT/Avelumab)

Carcinoma, Squamous Cell of Head and Neck

Netherlands
Daping Hospital and the Research Institute of Surgery...

Unknown

Concurrent Chemoradiotherapy(CRT) in Locally Advanced(LA) SCCHN vs Cetuximab With Radiotherapy (RT) After Neoadjuvant Chemotherapy

Carcinoma, Squamous Cell of Head and Neck
Ikena Oncology
Bristol-Myers Squibb

Withdrawn

Oral AHR Antagonist in Combination With Nivolumab in Patients With PD-1 Resistant Metastatic or Recurrent Head and Neck Cancer

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Head Cancer | Neck Cancer | Head Cancer Neck | Neck Carcinoma

United States
Merus N.V.

Recruiting

A Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR and Anti-c-MET Bispecific Antibody, in Patients With Advanced NSCLC and Other Solid Tumors

Gastric Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Non-Small Cell Lung Cancer Metastatic

United States, Spain, France, Italy, Netherlands, Belgium, Korea, Republic of, Germany, Singapore
National Baromedical Services
Mayo Clinic; Dartmouth-Hitchcock Medical Center; Eastern Virginia Medical School and other collaborators

Completed

Dose Escalation Study of Hyperbaric Oxygen With Radiation and Chemotherapy to Treat Squamous Cell Carcinoma of the Head and Neck (HBO-XRT)

Carcinoma, Squamous Cell | Cancer of the Head and Neck

United States
Providence Health & Services
Bristol-Myers Squibb

Active, not recruiting

Ipilimumab for Head and Neck Cancer Patients

Squamous Cell Carcinoma of the Head and Neck

United States
Celldex Therapeutics

Completed

A Window of Opportunity Study of KTN3379 in Surgically Resectable Head and Neck Cancer Patients

Squamous Cell Carcinoma of the Head and Neck

United States
National Cancer Institute (NCI)

Recruiting

Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage IV Hypopharyngeal... and other conditions

United States
Vanderbilt University Medical Center

Recruiting

3D Specimen Maps for RT Planning

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Radiation Therapy

United States
Genmab

Completed

Zalutumumab Pharmacokinetics (PK) in Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Head and Neck Cancer

United Kingdom, Belgium, Slovakia, Hungary
West Virginia University
West Virginia Clinical and Translational Science Institute

Terminated

Pilot Study of Metformin in HNSCC to Investigate the Effects of MF, Tumor Genotype and MF-genotype Interactions, on Tumor Metabolism and Anoikis

Cancer of Head and Neck

United States
Centre Hospitalier Universitaire, Amiens

Not yet recruiting

Intratumoral Gemcitabine, Paclitaxel, Carboplatine and Intravenous Nivolumab for Locally Recurrence of Head and Neck Cancers (NIVOCHIMLOC)

Squamous Cell Carcinoma of the Head and Neck | Paclitaxel | Nivolumab | Carboplatin

France
Dan Zandberg
Bristol-Myers Squibb

Active, not recruiting

Personalized Immunotherapy in Patients With Recurrent /Metastatic SCCHN That Have Progressed on Prior Immunotherapy

Squamous Cell Carcinoma of the Head and Neck

United States
Innate Pharma
AstraZeneca

Completed

Study of Monalizumab and Cetuximab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Head and Neck Neoplasms

United States, France

Clinical Trials on Metastatic Head-and-neck Squamous-cell Carcinoma

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