Clinical Trials on Metastatic Malignant Neoplasm to the Adult Brain
Total 2660 results
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University of UtahCompletedMultiple Sclerosis | Multiple Sclerosis, Secondary Progressive | Secondary Progressive Multiple SclerosisUnited States
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Northwestern UniversityNational Cancer Institute (NCI)RecruitingAdvanced Malignant Solid Neoplasm | Advanced Pancreatic Carcinoma | Metastatic Pancreatic Carcinoma | Refractory Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer... and other conditionsUnited States
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St. Jude Children's Research HospitalNovartis PharmaceuticalsCompletedGlioma | Neoplasms | Glioblastoma | Neoplasms, Neuroepithelial | Central Nervous System Neoplasms | Brain Cancer | Brain Tumor | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Pineoblastoma | Recurrent Medulloblastoma | CNS Tumor | Pediatric... and other conditionsUnited States
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Washington University School of MedicineAstraZenecaTerminatedKidney Cancer | Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Nonsmall Cell Lung Cancer | Cancer of the Ovary | Renal Cancer | Colorectal Carcinoma | Ovary Cancer | Cancer of Breast | Gastroesophageal Cancer | Cancer of the Pancreas | Cancer of the Breast | Cancer... and other conditionsUnited States
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Affiliated Hospital to Academy of Military Medical...Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Peking...RecruitingAge Range ≥16 Years, Gender Unlimited | Histopathology Confirmed Diffuse Large B-cell Lymphoma or High-grade B-cell Lymphoma | Received Prior First-line Chemotherapy for DLBCL or HGBL, Failed to Reach CR for Four Cycles, or Relapsed | At Least One Positive Lesion According to the 2014... and other conditionsChina
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M.D. Anderson Cancer CenterBristol-Myers Squibb; National Cancer Institute (NCI); Iovance BiotherapeuticsActive, not recruitingMalignant Solid Neoplasm | Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Platinum-Resistant Ovarian Carcinoma | Metastatic Pancreatic Ductal Adenocarcinoma | Metastatic Ovarian Carcinoma and other conditionsUnited States
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Rigel PharmaceuticalsNationwide Children's HospitalNot yet recruitingAstrocytoma | High Grade Glioma | Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | Spinal Tumor | Astrocytoma, Grade III | Astrocytoma, Grade IV | IDH1 Mutation | WHO Grade IV Glioma | Thalamus Tumor | IDH1 R132 | IDH1 R132C | IDH1 R132H and other conditionsUnited States, Australia, United Kingdom, Canada, Germany, Netherlands
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State University of New York at BuffaloCompletedSecondary-progressive Multiple SclerosisUnited States
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Tiziana Life Sciences LTDWithdrawnMultiple Sclerosis | Primary Progressive Multiple Sclerosis | Secondary Progressive Multiple Sclerosis
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Sun Yat-sen UniversityRecruitingBreast Cancer | Cognitive Impairment | Brain Metastases | Radiotherapy Side Effect | Gangliosidosis, GM1China
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Gustave Roussy, Cancer Campus, Grand ParisUnknownColorectal Cancer With a Resected Minimal Synchronous PC | Ovarian Metastases | Tumour Rupture in the Abdominal CavityFrance
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M.D. Anderson Cancer CenterCompletedMetastatic Carcinoma in the Adrenal Cortex | Stage III Adrenal Cortex Carcinoma AJCC v8 | Stage IV Adrenal Cortex Carcinoma AJCC v8 | Unresectable Adrenal Cortex CarcinomaUnited States
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Eli Lilly and CompanyCompletedMelanoma | Breast Cancer | Non-small Cell Lung Cancer | Brain MetastasesSpain, United States, Australia, Italy, France, Belgium, Canada, Austria, Israel
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Wake Forest University Health SciencesNational Cancer Institute (NCI)RecruitingVulvar Cancer | Recurrent Ovarian Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Invasive Breast Cancer | Malignant Uterine Neoplasm | Recurrent Breast Carcinoma and other conditionsUnited States
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University of Medicine and Dentistry of New JerseyNational Cancer Institute (NCI)WithdrawnRecurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent... and other conditionsUnited States
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Case Comprehensive Cancer CenterNational Cancer Institute (NCI)TerminatedLymphoma | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol SpecificUnited States
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Zhebao WuPeking Union Medical College Hospital; Beijing Tiantan Hospital; Huashan Hospital and other collaboratorsUnknownInvasive Prolactinomas Involving the Cavernous SinusChina
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Bristol-Myers SquibbNektar TherapeuticsTerminatedEwing Sarcoma | Ependymoma | Medulloblastoma | Neuroblastoma | Rhabdomyosarcoma | High-grade Glioma | Leukemia and Lymphoma | Miscellaneous Brain Tumors | Miscellaneous Solid Tumors | Relapsed, Refractory Malignant NeoplasmsUnited States, Australia, France, Germany, Italy, Spain
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Sidney Kimmel Comprehensive Cancer Center at Johns...National Cancer Institute (NCI)CompletedBrain and Central Nervous System TumorsUnited States
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National Cancer Institute (NCI)CompletedChronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) and other conditionsUnited States
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National Institute of Neurological Disorders and...CompletedBrain Neoplasm | Alzheimer's Disease | Niemann Pick DiseaseUnited States
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Rahul AggarwalNational Cancer Institute (NCI); U.S. Army Medical Research Acquisition ActivityRecruitingProstate Cancer | Advanced Solid Tumor | Renal Cancer | Urethral Cancer | Solid Tumor, Adult | Metastatic Castration-resistant Prostate CancerUnited States
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University of AarhusCompletedLaparoscopic Surgery | Postoperative Complications | Intestinal Neoplasms | Bleeding | Venous Thromboembolism | Peritoneal Carcinomatosis | Cytoreductive Surgery | Peritoneal Metastases | Laparoscopy | Surgical Procedures, Operative | Coagulation | Colorectal Neoplasms Malignant | Minimally Invasive Surgical Procedures and other conditionsDenmark
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OPKO Health, Inc.CompletedVitamin D Insufficiency | CKD Stage 4 | CKD Stage 3 | Secondary Hyperparathyroidism Due to Renal CausesUnited States
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Memorial Sloan Kettering Cancer CenterCompletedMelanoma | Sarcoma | Cervical Cancer | Breast Cancer | Pancreatic Cancer | Lung Cancer | Rectal Cancer | Prostate Cancer | Bladder Cancer | Colon Cancer | Brain Metastasis | Testicular Cancer | HEENT CancerUnited States
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Northwestern UniversityNational Cancer Institute (NCI)TerminatedRecurrent Adrenal Cortex Carcinoma | Stage III Adrenal Cortex Carcinoma | Stage IV Adrenal Cortex Carcinoma | Metastatic Carcinoma in the Adrenal CortexUnited States
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Teva Branded Pharmaceutical Products R&D, Inc.CompletedParkinson's Disease | Malignant Melanoma
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Nurix Therapeutics, Inc.RecruitingCervical Cancer | Gastric Cancer | Head and Neck Squamous Cell Carcinoma | Non-small Cell Lung Cancer (NSCLC) | Metastatic Urothelial Carcinoma | Ovarian Cancer, Epithelial | Metastatic Castration-resistant Prostate Cancer (mCRPC) | Triple Negative Breast Cancer (TNBC) | Malignant Pleural Mesothelioma... and other conditionsUnited States, United Kingdom
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Yale UniversityTerminatedMelanoma | Sarcoma | Renal Cell Carcinoma | Breast Cancer | Colorectal Cancer | Lung Cancer | Brain Metastases | Gastrointestinal CancersUnited States
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Black Diamond Therapeutics, Inc.RecruitingMelanoma | Colorectal Cancer | NSCLC | Solid Tumor | Metastatic Lung Cancer | Metastatic Lung Non-Small Cell Carcinoma | Metastatic Melanoma | Non-small Cell Lung Cancer | Histiocytosis | Melanoma (Skin) | Recurrent Melanoma | Thyroid Carcinoma | Thyroid Cancer | Brain Metastases | Recurrent Histiocytic and Dendritic... and other conditionsUnited States
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Stem Cell Medicine Ltd.WithdrawnSecondary Progressive Multiple Sclerosis (SPMS)Israel
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Novartis PharmaceuticalsCompletedSecondary Progressive Multiple Sclerosis (SPMS)Japan
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Wake Forest University Health SciencesCompletedUnspecified Childhood Solid Tumor, Protocol Specific | Pseudomyxoma Peritonei | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Ovarian Sarcoma | Recurrent Ovarian Epithelial Cancer | Stage IV Colon Cancer | Recurrent Colon Cancer | Carcinoma of the Appendix | Ovarian Stromal Cancer and other conditionsUnited States
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Eisai Co., Ltd.CompletedPartial Seizures (With or Without Secondary Generalized Seizures) | Primary Generalized Tonic-clonic SeizuresJapan
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Massachusetts General HospitalHeinz Family FoundationRecruitingBreast Cancer | Lymphedema | Edema | Lymphedema of Upper Arm | Breast Cancer Lymphedema | Breast Cancer Metastatic | Lymphedema of Upper Limb | Breast Cancer Stage | Lymphedema Arm | Edema Arm | Lymphedema of the HandsUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingGenetically Modified T-Cells Followed by Aldesleukin in Treating Patients With Stage III-IV MelanomaMetastatic Melanoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Stage IIIC Cutaneous Melanoma AJCC v7 | Stage IIIA Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma AJCC v7United States
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Escape Bio, Inc.Momentum Pharma; Science 37TerminatedPatients With Parkinson's Disease (PD) Caused by the p.Gly2019Ser (G2019S) Pathogenic Mutation of the Leucine-Rich Repeat Kinase 2 (LRRK2) GeneUnited States
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SanofiRecruitingRelapsing Multiple Sclerosis | Secondary Progressive Multiple Sclerosis | Progressive Relapsing Multiple SclerosisChina, Turkey, Korea, Republic of, United States, Ukraine
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Novartis PharmaceuticalsCompletedSecondary Progressive Multiple SclerosisGermany
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Tehran University of Medical SciencesCompletedMultiple Sclerosis | Mesenchymal Stem Cells | Secondary-Progressive Multiple SclerosisIran, Islamic Republic of
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Novartis PharmaceuticalsActive, not recruitingActive Secondary Progressive Multiple SclerosisItaly
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Novartis PharmaceuticalsTerminatedSecondary Progressive Multiple Sclerosis With Inflammatory Disease ActivitySwitzerland
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AB ScienceCompletedMultiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive | Multiple Sclerosis, Relapse FreePoland, Spain, Bulgaria, France, Germany, Greece, Romania
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingColorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Colorectal Carcinoma Metastatic in the LungUnited States, Canada
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Eisai Co., Ltd.CompletedPartial Seizures (With or Without Secondary Generalized Seizures) | Primary Generalized Tonic-clonic SeizuresJapan
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National Taiwan University HospitalUnknownAcute Renal Failure | Neuroleptic Malignant Syndrome | Rhabdomyolysis | MyopathyTaiwan
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National Cancer Institute (NCI)CompletedExtranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditionsUnited States
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Pamela MunsterPfizer; Xynomic Pharmaceuticals, Inc.WithdrawnAnatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditions
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City of Hope Medical CenterNational Cancer Institute (NCI)CompletedPrimary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid... and other conditionsUnited States
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AIO-Studien-gGmbHServier; Institut für Klinisch-Onkologische Forschung der Krankenhaus Nordwest...Active, not recruitingBiliary Tract Cancer | Extrahepatic Bile Duct Carcinoma | Non-Resectable Hepatocellular Carcinoma | Adenocarcinoma Metastatic | Adenocarcinoma of the Biliary Tract | Adenocarinoma Locally Advanced | Intrahepatic Bile Duct CarcinomaGermany