Clinical Trials on Metastatic Neoplasm

Total 107813 results

Vastra Gotaland Region
Isofol Medical AB

Unknown

Modelle 001, TS-inhibition in Colorectal Liver Metastases Comparing Arfolitixorin and Calciumfolinate

Metastatic Colorectal Cancer

Sweden
University Hospital, Tours

Completed

Evaluation of Contrast-enhanced Ultrasound Imaging for the Early Estimate of Bevacizumab Effect on Colorectal Cancer Liver Metastases

Metastatic Colorectal Cancer

France
GERCOR - Multidisciplinary Oncology Cooperative...

Completed

Combination Chemotherapy in Treating Patients With Colorectal Cancer and Resectable Metastases (MIROX)

Colorectal Cancer | Chemotherapy | Metastatic Cancer

France
Ronald Levy
Bristol-Myers Squibb

Completed

SD-101 and BMS-986178 in Treating Patients With Advanced or Metastatic Solid Malignancies

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Extracranial Solid Neoplasm

United States
Spanish Breast Cancer Research Group
Novartis Pharmaceuticals

Completed

Study of the Utility of the BOMET-QOL Questionnaire Patients With Breast Cancer and Bone Metastasis (MAbomet)

Breast Carcinoma Metastatic to the Bone

Spain
University Health Network, Toronto
British Columbia Cancer Agency; Terry Fox Research Institute

Active, not recruiting

Comprehensive Genomic Profiling of Colorectal Cancer Patients With Isolated Liver Metastases to Understand Response & Resistance to Cancer Therapy (COMPARISON)

Colorectal Cancer | Colorectal Cancer Metastatic | Hepatic Metastases

Canada
M.D. Anderson Cancer Center

Withdrawn

BAY1895344 and Copanlisib for the Treatment of Molecularly Selected Patients With Advanced Solid Tumors

Locally Advanced Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Bone
University of Southern California
National Cancer Institute (NCI); Auransa, Inc.

Recruiting

AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Advanced Hepatocellular Carcinoma | Metastatic Malignant Neoplasm in the Liver | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Advanced Cholangiocarcinoma

United States
Roswell Park Cancer Institute

Recruiting

Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases

Colorectal Cancer | Metastatic Unresectable Sarcoma | Metastatic Malignant Neoplasm in the Lung | Resectable Sarcoma | Metastatic Soft Tissue Sarcoma | Metastatic Bone Sarcoma

United States
Incyte Biosciences International Sàrl

Completed

A Study of INCAGN01876 in Participants With Advanced or Metastatic Solid Tumors

Metastatic Cancer | Advanced Malignancies

United States
University Medical Center Groningen

Recruiting

Gut Microbiome Dynamics in Metastasized or Irresectable Colorectal Cancer (GIMICC)

Colorectal Cancer Metastatic

Netherlands
Rigshospitalet, Denmark

Recruiting

Stereotactic Body Radiation Therapy vs. Microwave Ablation for Colorectal Cancer Patients With Metastatic Disease in the Liver

Liver Metastases | Colorectal Carcinoma

Denmark
Centre Hospitalier Universitaire de Besancon
Bayer

Completed

Regorafenib in Combination With Metronomic Chemotherapies, and Low-dose Aspirin in Metastatic Colorectal Cancer (REPROGRAM-01)

Metastatic Cancer | Colo-rectal Cancer

France
Sun Yat-sen University

Unknown

The Gene Profiles of Primary and Heterogeneous Metastases of Colorectal Cancer

Metastatic Colorectal Cancer

China
Herbert Irving Comprehensive Cancer Center

Completed

Topotecan and Paclitaxel in Treating Patients With Recurrent or Metastatic Cancer of the Cervix

Cervical Cancer

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Brain

United States
National Cancer Institute (NCI)

Recruiting

Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With AKT Mutations, A ComboMATCH Treatment Trial

Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Puerto Rico
National Cancer Institute (NCI)

Active, not recruiting

Atezolizumab in Treating Patients With Cancer Following Adoptive Cell Transfer

Hematopoietic and Lymphoid Cell Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Canada
University of California, San Francisco

Completed

Integrative Palliative Care/Psycho-Oncology Telehealth Intervention in Patients With Advanced Cancer

Advanced Malignant Solid Neoplasm | Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Calico Life Sciences LLC
AbbVie

Recruiting

A Phase 1 Study With ABBV-CLS-484 in Subjects With Locally Advanced or Metastatic Tumors

Advanced Solid Tumor Cancer

United States, Korea, Republic of, Spain, Israel, Japan, France
Technical University of Munich

Terminated

Resection in Pancreatic Cancer With Minimal Metastatic Disease or Venous Infiltration Trial at Technische Universität München (PaMeViTUM)

Pancreatic Cancer

Germany
Indiana University

Completed

Mindfulness to Enhance Quality of Life and Support Advance Care Planning (MEANING)

Quality of Life | Metastatic Cancer | Palliative Care | Supportive Care | Meditation | Mindfulness | Advance Care Planning | Family Caregiver

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of XL184 (Cabozantinib), Nivolumab, and Ipilimumab for Poorly Differentiated Neuroendocrine Tumors

Metastatic Neuroendocrine Neoplasm | Metastatic Neuroendocrine Carcinoma | Metastatic Large Cell Neuroendocrine Carcinoma | Metastatic Small Cell Neuroendocrine Carcinoma

United States, Canada
Jules Bordet Institute

Withdrawn

Kadcyla In pAtients With bRAin Metastasis (KIARA)

Metastatic HER2-positive Breast Cancer With Brain Metastasis
Hoffmann-La Roche

Completed

A Study of Bevacizumab (Avastin) in Combination With Chemotherapy in Participants With Metastatic Cancer of the Colon or Rectum

Colorectal Cancer

Taiwan
Hoffmann-La Roche

Completed

OBELIX Study: A Study of Avastin (Bevacizumab) in Combination With XELOX in Patients With Metastatic Cancer of the Colon or Rectum.

Colorectal Cancer

Italy
Washington University School of Medicine
United States Department of Defense; Aclaris Therapeutics, Inc.

Not yet recruiting

Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis

Hormone Receptor Positive HER-2 Negative Metastatic Breast Cancer

United States
M.D. Anderson Cancer Center

Active, not recruiting

Avelumab and M6620 for the Treatment of DDR Deficient Metastatic or Unresectable Solid Tumors

Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Roswell Park Cancer Institute

Recruiting

Single-Fraction SBRT Versus Standard Palliative Radiation Therapy in Treating Patients With Metastatic Cancer

Metastatic Malignant Neoplasm

United States
M.D. Anderson Cancer Center
Genentech, Inc.; Seagen Inc.

Recruiting

A Phase II Study of Tucatinib and Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2-positive Metastatic Solid Tumors and Metastases to Brain (TUCATEMEB)

Metastatic Solid Tumor | Brain Metastases

United States
Virginia Commonwealth University

Terminated

Impact of Cognitive Rehab and Physical Activity on Cognition in Patients With Metastatic Brain Tumors Undergoing RT

Metastatic Brain Tumor | Cerebral Metastases

United States
Fudan University

Unknown

Expression of Molecular Markers in Circulating Tumor Cells of Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer Metastatic

China
Enzon Pharmaceuticals, Inc.

Terminated

Efficacy of Pegamotecan (PEG-Camptothecin) in Localized or Metastatic Cancer of the Stomach or Gastroesophageal Junction

Cancer of Stomach | Gastroesophageal Cancer
Memorial Sloan Kettering Cancer Center
AstraZeneca

Recruiting

Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer

Glioblastoma | Brain Cancer | Metastatic Cancer | Recurrent Glioblastoma | Leptomeningeal Metastasis

United States
National Cancer Institute (NCI)

Active, not recruiting

Trametinib and Navitoclax in Treating Patients With Advanced or Metastatic Solid Tumors

Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Immunotherapy (Nivolumab With or Without Ipilimumab) in Patients With Advanced Solid Cancers That Have Changes in the Following Genes: PIK3CA and PTEN

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Canada
Suzhou Transcenta Therapeutics Co., Ltd.

Terminated

Study of TST005 in Patients With Locally Advanced or Metastatic Solid Tumors

Locally Advanced or Metastatic Cancers | Metastatic Human Papillomavirus-Related Malignant Neoplasm

United States
Shanghai Henlius Biotech

Recruiting

A Study Evaluating the Safety, Tolerability, Pharmacokinetic and Efficacy of HLX301(TIGIT×PDL1 Bispecific) in Locally Advanced/Metastatic Solid Tumors or Lymphoma (HLX301)

Lymphoma | Advanced Tumors | Metastatic Tumors

China
Hoffmann-La Roche

Completed

A Study of Bevacizumab (Avastin) in Combination With Chemotherapy in Participants With Metastatic Cancer of the Colon or Rectum.

Colorectal Cancer

Brazil
Hoffmann-La Roche

Completed

An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Cancer of the Colon or Rectum

Colorectal Cancer

Montenegro
Verastem, Inc.

Recruiting

Study of Avutometinib (VS-6766) +Defactinib With Gemcitabine and Nab-paclitaxel in Patients With Pancreatic Cancer (RAMP205)

Metastatic Cancer | Pancreas Cancer | Neoplasms Pancreatic | KRAS Activating Mutation | Malignant Neoplasm of Pancreas

United States
I-Mab Biopharma Co. Ltd.

Recruiting

Study of TJ033721 in Subjects With Advanced or Metastatic Solid Tumors

Gastric Cancer | Solid Tumor | Metastatic Cancer | Advanced Cancer | Esophageal Adenocarcinoma | Gastroesophageal Junction Carcinoma

United States, China
University Health Network, Toronto

Recruiting

In Vivo Lung Perfusion (IVLP) for Colorectal Cancer Metastatic to Lung

Colorectal Cancer | Lung Metastases | Colorectal Cancer Metastatic

Canada
The Christie NHS Foundation Trust

Not yet recruiting

Irinotecan Drug-eluting Bead Liver Embolisation Registry (DLivERDEBIRI)

Colorectal Cancer Metastatic | Liver Metastases

United Kingdom
Imunon

Completed

A Study of ThermoDox™ in Combination With Radiofrequency Ablation (RFA) in Primary and Metastatic Tumors of the Liver

Liver Neoplasms | Hepatocellular Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Antiandrogen Therapy With or Without Axitinib Before Surgery in Treating Patients With Previously Untreated Prostate Cancer With Known or Suspected Lymph Node Metastasis

Metastatic Malignant Neoplasm in Lymph Node | Prostate Ductal Adenocarcinoma | Stage III Prostate Adenocarcinoma AJCC v7 | Stage IV Prostate Adenocarcinoma AJCC v7

United States
Melanoma and Skin Cancer Trials Limited
University of Oxford; Trans Tasman Radiation Oncology Group

Active, not recruiting

Whole Brain Radiotherapy Following Local Treatment of Intracranial Metastases of Melanoma (WBRTMel)

Metastatic Melanoma

Norway, Australia, United Kingdom
Centre Hospitalier Universitaire de Nīmes

Completed

Circulating Tumor Cells and Melanoma: Comparing the EPISPOT and CellSearch Techniques

Metastatic Melanoma

France
Hadassah Medical Organization

Unknown

Modified Melanoma Vaccine for High Risk or Low Residual Disease Patients

Metastatic Disease | High Risk HLA-A2+ Melanoma
Northwest Biotherapeutics
Mayo Clinic

Unknown

Dendritic Cell Therapy for Brain Metastases From Breast- or Lung Cancer

Lung Cancer Metastatic | Brain Metastases | Breast Cancer Metastatic

United States

Clinical Trials on Metastatic Neoplasm

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