Clinical Trials on Metastatic Unresectable Sarcoma

Total 12192 results

Daiichi Sankyo, Inc.
Plexxikon

Terminated

A Phase 1b Open Label, Dose Escalation Study of PLX3397 in Combination With Vemurafenib in V600-mutated BRAF Melanoma

V600-mutated BRAF Unresectable Melanoma | V600-mutated BRAF Metastatic Melanoma | Stage III or Stage IV Metastatic Melanoma That Has Not Been Previously Treated With a Selective BRAF Inhibitor

United States, Germany, France
Jiangxi Provincial Cancer Hospital

Recruiting

High- and Low-dose Radiotherapy Combined With Envafolimab for Metastatic Solid Tumor (ST-CR01)

Metastatic Cancer

China
Gustave Roussy, Cancer Campus, Grand Paris
Roche Pharma AG

Recruiting

Implementing Precision Medicine in cOmmunity HospiTALs (PRISM-POrTAL)

Metastatic Cancer

France
Lawson Health Research Institute
VU University of Amsterdam; London Regional Cancer Program, Canada

Active, not recruiting

Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastatic Tumors (SABR-COMET) (SABR-COMET)

Metastatic Tumors

Canada, Australia, Netherlands, United Kingdom
Milton S. Hershey Medical Center

Completed

Exercise Therapy in Radiation Therapy (EXERT)

Metastatic Cancer

United States
Hoffmann-La Roche

Completed

Study to Explore the Mechanism of Acquired Immune Escape In Participants With Metastatic Cancer Progressing on CPI Therapy

Neoplasms

United States, France, Spain, Korea, Republic of, United Kingdom
Alliance Foundation Trials, LLC.
Patient-Centered Outcomes Research Institute; Mayo Clinic; Dana-Farber Cancer... and other collaborators

Active, not recruiting

Electronic Patient Reporting of Symptoms During Cancer Treatment (PRO-TECT)

Metastatic Cancer

United States
National Institutes of Health Clinical Center (CC)

No longer available

Single Patient Protocol: A Phase II Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated Neoantigens in a Patient With Metastatic Cancer Plus the Administration of Pembrolizumab
Jonsson Comprehensive Cancer Center

Completed

Radiation Therapy Following Surgery to Remove Brain Metastases

Metastatic Cancer

United States
Eli Lilly and Company

Completed

A Study of LY3007113 in Participants With Advanced Cancer

Metastatic Cancer

United States
Viatar LLC

Unknown

Evaluation of Viatar™ Oncopheresis System in Removing CTC From Whole Blood

Metastatic Cancer
Memorial Sloan Kettering Cancer Center

Completed

Study Using High-Dose Single Fraction Image-Guided Radiotherapy for Metastatic Lesions to Soft Tissue Masses, Lymph Node, or Bone

Metastatic Disease

United States
Eli Lilly and Company

Completed

A Study of LY2624587 in Patients With Advanced Cancer

Metastatic Cancer

United States
Maastricht Radiation Oncology
Karolinska Institutet; KU Leuven; Maastricht University Medical Center; Catholic... and other collaborators

Withdrawn

Combination of SABR and L19-IL2 in Patients With Stage IV Lung Cancer (ImmunoSABR) (ImmunoSABR)

NSCLC Stage IV | Limited Metastatic Disease

Netherlands
Shanghai Zhongshan Hospital
Fudan University

Recruiting

Surufatinib Combined With KN046 and AG Regimen Chemotherapy as First-Line Treatment for Unresectable Advanced Pancreatic Cancer

Unresectable Locally Advanced or Metastatic Pancreatic Cancer

China
BeiGene

Recruiting

A Study Investigating the Efficacy and Safety of LBL-007 Plus Tislelizumab in Combination With Bevacizumab Plus Fluoropyrimidine Versus Bevacizumab Plus Fluoropyrimidine in Participants With Unresectable or Metastatic Colorectal Cancer

Unresectable or Metastatic Microsatellite Stable/Mismatch Repair Proficient Colorectal Cancer

China, United States, Australia, Puerto Rico
Advenchen Laboratories, LLC

Active, not recruiting

Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS) (APROMISS)

Leiomyosarcoma | Synovial Sarcoma | Alveolar Soft Part Sarcoma | Soft-Tissue Sarcoma

United States, United Kingdom, Spain, China, Italy
University Hospital, Ghent

Completed

Feasibility of Radiotherapy and Concomitant Gemcitabine and Oxaliplatin in Locally Advanced Pancreatic Cancer and Distal Cholangiocarcinoma

Locally Advanced and Unresectable, But Non-metastatic Pancreatic Adenocarcinoma or Cholangiocarcinoma

Belgium
Infinity Pharmaceuticals, Inc.

Completed

Safety Study of IPI-504 in Patients With Gastrointestinal Stromal Tumors (GIST) or Soft Tissue Sarcomas (STS)

Gastrointestinal Stromal Tumors | Soft Tissue Sarcomas

United States, Canada
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Fluorothymidine F-18 PET in Diagnosing Patients With Intermediate or High Grade Soft Tissue Sarcoma

Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Stage II Adult Soft Tissue Sarcoma | Stage IIA Adult Soft Tissue Sarcoma | Stage IIB Adult Soft Tissue Sarcoma | Stage IIC Adult Soft Tissue Sarcoma
National Cancer Institute (NCI)

Completed

Everolimus in Combination With Imatinib Mesylate in Treating Patients With Locally Advanced, Locally Recurrent, or Metastatic Soft Tissue Sarcoma

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Adult Synovial Sarcoma

United States
National Institutes of Health Clinical Center (CC)

Completed

Isolated Limb Perfusion of Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Soft Tissue Sarcoma of the Arm or Leg

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IVA Adult Soft Tissue Sarcoma | Stage IIB Adult Soft Tissue Sarcoma | Stage IIC Adult Soft Tissue Sarcoma | Stage IVB Adult Soft Tissue Sarcoma
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Autologous T Cells and Cyclophosphamide in Treating Patients With Soft Tissue Sarcoma That is Metastatic or Cannot Be Removed By Surgery

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Adult Liposarcoma | Adult Synovial Sarcoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed By Stem Cell Rescue in Treating Patients With Poor-Risk Ewing Sarcoma

Ewing Sarcoma of Bone | Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Adult Supratentorial Primitive Neuroectodermal Tumor (PNET) and other conditions

United States
National Cancer Institute (NCI)

Completed

Tanespimycin in Treating Young Patients With Recurrent or Refractory Leukemia or Solid Tumors

Childhood Chronic Myelogenous Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Childhood Rhabdomyosarcoma | Metastatic Osteosarcoma | Disseminated Neuroblastoma | Previously Treated... and other conditions

United States
University Health Network, Toronto

Recruiting

Patient Reported Outcomes/Metrics Program Trial (PROMPT)

Metastatic Cancer | Palliative

Canada
University of Colorado, Denver
Cancer League of Colorado

Recruiting

Biomarkers of Immune-Related Toxicity

Cancer | Metastatic Cancer

United States
Lycera Corp.

Completed

Study of LYC-55716 in Adult Subjects With Locally Advanced or Metastatic Cancer

Cancer

United States
Massachusetts General Hospital

Completed

Biopsies of Cancer Patients for Tumor Molecular Characterization

Cancer | Metastatic Cancer

United States
Genta Incorporated

Unknown

Tesetaxel Every 3 Weeks vs Weekly vs Capecitabine as 1st-line Therapy for Locally Advanced or Metastatic Breast Cancer

Metastatic Breast Cancer | Locally Advanced Non-resectable Breast Cancer

United States
Istituto Scientifico Romagnolo per lo Studio e...

Recruiting

Radiometabolic Therapy With 177Lu PSMA in PSMA PET/CT Positive Advanced/Metastatic Tumours: (LUBASKET)

Cancer

Italy
Beyond Air Inc.

Recruiting

A Study to Assess the Safety and Efficacy of Nitric Oxide Injection Into Unresectable Solid Primary or Metastatic Tumors

Cancer

Israel
Elevar Therapeutics

Completed

A Study to Evaluate Apatinib (Also Known as Rivoceranib) Plus Nivolumab in Participants With Unresectable or Metastatic Cancer

Cancer

United States
University of Wisconsin, Madison
National Cancer Institute (NCI)

Terminated

Interleukin-12 Gene Therapy in Treating Patients With Skin Metastases

Metastatic Cancer

United States
University of Rochester

Completed

A Study For Using Radiosurgery On Limited Metastases

Neoplasms, Metastatic

United States
Prescient Therapeutics, Ltd.
VioQuest Pharmaceuticals

Completed

Phase I Study of Triciribine Phosphate Monohydrate (TCN-PM, VD-0002) in Adult Subjects With Metastatic Cancer

Cancer

United States
Endocyte

Completed

Safety and Tolerability Study of FolateImmune in Combination With Cytokines in Patients With Refractory or Metastatic Cancer

Cancer

United States
Immune Design
Merck Sharp & Dohme LLC

Completed

Phase 1 Study of Intradermal LV305 in Patients With Locally Advanced, Relapsed or Metastatic Cancer Expressing NY-ESO-1

Melanoma - Currently Enrolling | Non-small Cell Lung Cancer - Enrollment Completed | Sarcoma - Enrollment Completed

United States
AIO-Studien-gGmbH
Servier

Completed

Nal-IRI and 5-FU Compared to 5-FU in Patients With Cholangio- and Gallbladder Carcinoma Previously Treated With Gemcitabine-based Therapies (NALIRICC)

Cholangiocarcinoma Non-resectable | Cholangiocarcinoma of the Gallbladder | Cholangiocarcinoma Metastatic | Cholangiocarcinoma Advanced

Germany
Hospital Universitari de Bellvitge
Instituto de Salud Carlos III

Terminated

Resection vs no Resection of the Primary in Colorectal Cancer With Unresectable Metastases (CCRe-IV)

Colonic Cancer | Unresectable Metastasis Originating in Colonic Cancer

Spain
National Cancer Institute (NCI)
NRG Oncology

Terminated

Gemcitabine Hydrochloride and Docetaxel With or Without Bevacizumab in Treating Patients With Advanced or Recurrent Uterine Leiomyosarcoma

Recurrent Uterine Corpus Sarcoma | Uterine Corpus Leiomyosarcoma | Stage IIIA Uterine Sarcoma | Stage IIIB Uterine Sarcoma | Stage IIIC Uterine Sarcoma | Stage IVA Uterine Sarcoma | Stage IVB Uterine Sarcoma

United States
University of Washington
Steven & Alexandra Cohen Foundation

Active, not recruiting

Psilocybin-Assisted Therapy for the Treatment of Cancer-Related Anxiety in Patients With Metastatic Cancer

Metastatic Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Children's Oncology Group
National Cancer Institute (NCI); University College, London; Medical Research...

Completed

Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma (EURAMOS-1)

Metastatic Osteosarcoma | Localized Osteosarcoma

United States, Canada, Australia, New Zealand, Puerto Rico, Switzerland
M.D. Anderson Cancer Center

Active, not recruiting

Sintilimab for the Treatment of Locally Advanced, Metastatic, or Recurrent Angiosarcoma, the SiARa Cancer Study

Locally Advanced Angiosarcoma | Metastatic Angiosarcoma | Recurrent Angiosarcoma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Jazz Pharmaceuticals

Terminated

Combination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk Osteosarcoma

Metastatic Osteosarcoma

United States
Italian Sarcoma Group

Completed

Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable Osteosarcoma (SERIO)

Metastatic Osteosarcoma | Relapsed Osteosarcoma

Italy
National Cancer Institute (NCI)

Active, not recruiting

Testing the Biological Effects of DS-8201a on Patients With Advanced Cancer

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | HER2-Positive Breast Carcinoma

United States
Devalingam Mahalingam
Amgen

Withdrawn

Study of Sotorasib Combined With Chemotherapy for Second Line Treatment of Pancreas Cancer

Pancreatic Cancer | Metastatic Pancreatic Cancer | Unresectable Pancreatic Cancer | KRAS P.G12C

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Study of Specimens From Young Patients With Neuroblastoma

Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma

United States
National Cancer Institute (NCI)

Terminated

18F-Fluoromisonidazole and Fludeoxyglucose F 18 PET/CT Patients With Soft Tissue Sarcoma

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Stage I Adult Soft Tissue Sarcoma | Stage II Adult Soft Tissue Sarcoma

United States

Clinical Trials on Metastatic Unresectable Sarcoma

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CROs in Norway

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