Clinical Trials on Metastatic Unresectable Sarcoma

Total 12288 results

Novita Pharmaceuticals, Inc.
Translational Drug Development

Completed

Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies

Breast Cancer | Lung Cancer | Prostate Cancer | Colon Cancer | Pancreas Cancer | Liver Cancer | Ovary Cancer | Esophagus Cancer | Advanced or Metastatic Treatment-refractory Solid Tumor Malignancies

United States
National Cancer Institute (NCI)

Unknown

Disease-Specific Questionnaire in Assessing Quality of Life in Patients With Gastrointestinal-Related Neuroendocrine Tumors

Lung Cancer | Metastatic Cancer | Islet Cell Tumor | Gastrointestinal Carcinoid Tumor | Neoplastic Syndrome

Spain, United Kingdom, Germany, Netherlands, Israel, Sweden, Poland, Denmark, Greece, Italy
Actuate Therapeutics Inc.

Active, not recruiting

9-ING-41 in Patients With Advanced Cancers

Sarcoma | Cancer | Breast Neoplasms | Neoplasm Metastasis | Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Bone Cancer | Malignant Glioma | Bone Metastases | Pancreas Cancer | Renal Cancer | Refractory Non-Hodgkin Lymphoma | Bone Neoplasm | Neoplasm, Breast | Refractory Cancer | Refractory Neoplasm | Resistant... and other conditions

United States, Belgium, Canada, Spain, France, Netherlands, Portugal
University of Chicago
National Cancer Institute (NCI)

Completed

PI3K Inhibitor BKM120 and Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
Mirati Therapeutics Inc.

Recruiting

Phase 1/2 Study of MRTX1719 in Solid Tumors With MTAP Deletion

Pancreatic Adenocarcinoma | Solid Tumor | Non Small Cell Lung Cancer | Mesothelioma | Advanced Solid Tumor | Malignant Peripheral Nerve Sheath Tumors

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Development of Strategies to Increase Enrollment in Clinical Trials for Children With Cancer

Sarcoma | Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Liver Cancer | Psychosocial Effects of Cancer and Its Treatment | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States, Puerto Rico, Canada, Switzerland
National Cancer Institute (NCI)

Completed

Voriconazole in Preventing Fungal Infections in Children With Neutropenia After Chemotherapy

Sarcoma | Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Neutropenia | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
University of Nottingham
Wellcome Trust

Not yet recruiting

Measuring and Mapping Cognitive Decline After Brain Radiosurgery (CoDeB-Rad)

Quality of Life | Cognitive Decline | Brain Metastases | SRS | Meningiomas | Stereotactic Radiosurgery

United Kingdom
Boryung Pharmaceutical Co., Ltd

Recruiting

A Observational Study to Evaluate the Efficacy and Safety of Pacitol Inj.

Secondary Hyperparathyroidism | Chronic Kidney Disease 5D

Korea, Republic of
Novartis Pharmaceuticals

Completed

Long Term Efficacy and Safety of Zoledronic Acid Treatment in Patients With Bone Metastases

Bone Neoplasms

Australia
University Hospital, Ghent

Terminated

Hair-sparing Whole Brain Radiotherapy

Small Cell Lung Cancer | Brain Metastases

Belgium
Sun Yat-sen University
Novartis

Completed

Screening Non Small Cell Lung Cancer With Bone Metastasis and Efficacy and Safety Research of Receiving Bisphosphonates (BLEST)

Bone Metastases | Non-small Cell Lung Cancer

China
Association of Urologic Oncology (AUO)
University Hospital, Essen

Unknown

Resection of Pulmonary Metastasis in Clear Cell Renal Cell Carcinoma +/-Adjuvant Sunitinib Therapy (SMAT) (SMAT)

Renal Cell Carcinoma | Pulmonary Metastases

Germany
IRCCS San Raffaele

Recruiting

Study on the Quality of Life and Pathological State in Patients Who Underwent Radical Cystectomy

Bladder Cancer | Muscle-Invasive Bladder Carcinoma | Radical Cystectomy | Urinary Diversion | Bladder Urothelial Carcinoma | Progression, Disease | Bladder Cancer Stage II | Bladder Cancer Stage IV | Muscle Invasive Bladder Urothelial Carcinoma | Neobladder | Bladder Cancer TNM Staging | Bladder Cancer Stage... and other conditions

Italy
National Cancer Institute (NCI)

Active, not recruiting

Natural History Study of Patients With Neurofibromatosis Type I

Neurofibroma | Neurofibromatosis Type 1 | Malignant Peripheral Nerve Sheath Tumor | Optic Glioma | Plexiform Neurofibroma

United States
Rain Oncology Inc

Terminated

Milademetan in Advanced/Metastatic Solid Tumors

Melanoma | Sarcoma | Cervical Cancer | Testicular Germ Cell Tumor | Gastric Cancer | Non Small Cell Lung Cancer | Cholangiocarcinoma | Lung Adenocarcinoma | Solid Tumors | Pancreas Cancer | Head and Neck Carcinoma | Biliary Tract Cancer | Ovarian Carcinoma | Adrenocortical Carcinoma | Bladder Urothelial Carcinoma | Breast... and other conditions

United States
Corcept Therapeutics

Completed

Mifepristone and Eribulin in Patients With Metastatic Triple Negative Breast Cancer or Other Specified Solid Tumors

Sarcoma | Breast Cancer | Prostatic Neoplasms | Carcinoma, Transitional Cell | Prostate Cancer | Non-small Cell Lung Cancer | Ovarian Epithelial Cancer Recurrent

United States
National Cancer Institute (NCI)

Withdrawn

Testing a New Anti-cancer Drug Combination, Entinostat and GSK525762C, for Advanced and Refractory Solid Tumors and Lymphomas

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory B-Cell Non-Hodgkin Lymphoma | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Pancreatic Carcinoma | Refractory T-Cell Non-Hodgkin Lymphoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC... and other conditions
Salubris Biotherapeutics Inc

Recruiting

Study of JK08 in Patients With Unresectable Locally Advanced or Metastatic Cancer

Melanoma | Clear Cell Renal Cell Carcinoma | Cancer | Hepatocellular Carcinoma | Colorectal Cancer | Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Metastatic Cancer | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Cancer | Advanced Solid Tumor | Epithelial Ovarian Cancer | Non-small Cell... and other conditions

Belgium, Spain
Pathalys Pharma
Launch Therapeutics

Recruiting

Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-2 (PATH-2)

Secondary Hyperparathyroidism | End Stage Kidney Disease

United States, Bulgaria, Portugal, Spain, Serbia, Poland
Fudan University

Recruiting

Effect of Hepatectomy on the Prognosis of Patients With Nasopharyngeal Carcinoma Liver Metastases

Nasopharyngeal Carcinoma | Liver Metastases

China
Angiochem Inc

Not yet recruiting

ANG1005 in Leptomeningeal Disease From Breast Cancer (ANGLeD)

Brain Metastases | Leptomeningeal Metastases | HER2-negative Breast Cancer | Leptomeningeal Carcinomatosis
Hospices Civils de Lyon

Unknown

Association of Bone and Metabolic Parameters With Overall Survival in Patients With Bone Metastases From Adenocarcinoma Lung Cancer (POUMOS) (POUMOS)

Lung Cancer | Bone Metastases

France
KAI Pharmaceuticals

Terminated

Open-label Study to Assess the Long-term Safety and Efficacy of Etelcalcetide (Also Known as AMG 416 or KAI-4169) in Patients With Secondary Hyperparathyroidism

Secondary Hyperparathyroidism
Shandong Cancer Hospital and Institute
AstraZeneca

Unknown

Open Label, Prospective Study to Investigate Efficacy and Safety of AZD9291 in BM From NSCLC Patients With EGFR T790M

Nonsmall Cell Lung Cancer | Brain Metastases | EGFR-TKI Resistant Mutation | AZD9291
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer

Liver Metastases | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
National Cancer Institute (NCI)

Completed

Whole Body Fluorine F 18 Sodium Fluoride PET/CT Scan and Whole Body MRI in Finding Bone Metastases in Patients With Prostate Cancer

Recurrent Prostate Cancer | Bone Metastases | Stage I Prostate Cancer | Stage III Prostate Cancer | Stage IV Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

SU5416 in Treating Patients With Advanced or Recurrent Cancer of the Head and Neck

Head and Neck Cancer | Non-melanomatous Skin Cancer | Carcinoma of Unknown Primary

United States
Novartis

Completed

Efficacy and Safety of Zoledronic Acid in Patients With Bone Metastases of Any Solid Tumors or Multiple Myeloma

Treatment of Bone Metastases

China
St. Louis University

Recruiting

Post-Op Pain Control for Prophylactic Intramedullary Nailing.

Pain | Lymphoma | Multiple Myeloma | Bone Metastases | Opioid Use

United States
Chang Gung Memorial Hospital

Recruiting

Hippocampal-Sparing Prophylactic Cranial Irradiation in Pathologically Nodal Positive Non-Small-Cell Lung Cancer

Brain Metastasis | Non-Small-Cell Lung Cancer (NSCLC)

Taiwan
UNICANCER
Merck Sharp & Dohme LLC; Pierre Fabre Medicament; European Association of Dermato...

Active, not recruiting

Binimetinib Encorafenib Pembrolizumab +/- Stereotactic Radiosurgery in BRAFV600 Melanoma With Brain Metastasis (BEPCOME-MB)

Brain Metastases | Malignant Melanoma | BRAF V600 Mutation

France
Jeffrey Clarke
Genentech, Inc.; Duke University

Terminated

Chemotherapy and Atezolizumab for Patients With Extensive Stage Small Cell Lung Cancer (SCLC) With Untreated, Asymptomatic Brain Metastases

Small-cell Lung Cancer | Brain Metastases

United States
Pfizer
Arena is a wholly owned subsidiary of Pfizer

Terminated

A Study to Assess the Effect of Oral Temanogrel on Digital Blood Flow in Adult Participants With Raynaud's Phenomenon Secondary to Systemic Sclerosis

Raynaud's Phenomenon Secondary to Systemic Sclerosis

United Kingdom, United States
National Cancer Centre, Singapore

Terminated

Afatinib on CNS Metastases and LMD in EGFR Mutation Positive NSCLC

Non-small Cell Lung Cancer | Leptomeningeal Disease | Central Nervous System Metastases

Singapore
Universidade de Passo Fundo

Completed

Oral Probiotics and Secondary Bacterial Pneumonia in Severe COVID-19

Microbial Colonization | Severe COVID-19 | COVID-19 Lower Respiratory Infection | Secondary Bacterial Pneumonia

Brazil
University of Louisville
Novartis Pharmaceuticals; James Graham Brown Cancer Center

Terminated

Using TRAP to Evaluate the Effect of Zometa on Bone Metastasis Due to Lung Cancer

Carcinoma, Non-Small Cell Lung | Metastases | Carcinoma, Small Cell Lung

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

Ruxolitinib Phosphate, Tacrolimus and Sirolimus in Preventing Acute Graft-versus-Host Disease During Reduced Intensity Donor Hematopoietic Cell Transplant in Patients With Myelofibrosis

Primary Myelofibrosis | Secondary Acute Myeloid Leukemia | Secondary Myelofibrosis | Acute Myeloid Leukemia in Remission | Primary Myelofibrosis, Prefibrotic Stage

United States
University of Utah
National Cancer Institute (NCI)

Terminated

Reversible Secondary Myelofibrosis or Clonal Myeloproliferative Disorder

Primary Myelofibrosis | Pulmonary Arterial Hypertension | Secondary Myelofibrosis | Primary Pulmonary Hypertension

United States
Shanghai Chest Hospital

Unknown

Comparator-Controlled Study for EGFR(+) Patients With Multiple BMs From NSCLC (BROKE) (EGFR-epidermal Growth Factor Receptor;BM-brain Metastases) (EGFR)

Non-Small Cell Lung Cancer | Brain Metastases | EGFR Gene Mutation

China
Wuhan University
NPO Organization to Support Peritoneal Dissemination Treatment; Kishiwada Tokushukai... and other collaborators

Unknown

Surgery Plus Intraoperative Peritoneal Hyperthermic Chemotherapy (IPHC) to Treat Peritoneal Carcinomatosis (IPHC)

Stomach Neoplasms | Neoplasm Metastasis | Colorectal Neoplasms | Mesothelioma

China
Pfizer

Recruiting

A Study in Advanced/Metastatic Solid Tumors With the Study Medicine (PF-07329640) When Given Alone or In Combination (LTbR)

Melanoma | Colorectal Cancer | Non-Small Cell Lung Cancer | Urothelial Cancer | Advanced or Metastatic Solid Tumors

United States, Puerto Rico
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases

Intrahepatic Cholangiocarcinoma | Gallbladder Carcinoma | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Metastatic Malignant Neoplasm in the Peritoneum | Distal Bile Duct Adenocarcinoma | Stage IV Distal Bile Duct Cancer AJCC v8 | Stage IV Intrahepatic Bile Duct Cancer AJCC v8 | Stage IVB Gallbladder...

United States
Pfizer

Recruiting

Mevrometostat Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

Small Cell Lung Cancer (SCLC) | Follicular Lymphoma (FL) | Metastatic Castration Resistant Prostate Cancer (mCRPC)

United States, Spain, Korea, Republic of, Poland, China, Bulgaria, Russian Federation, Japan
HiberCell, Inc.
Covance

Completed

A Study of HC-5404-FU to Establish the Maximum Tolerated Dose (MTD)

Renal Cell Carcinoma | Gastric Cancer | Metastatic Breast Cancer | Small-cell Lung Cancer | Other Solid Tumors

United States
Evelo Biosciences, Inc.
Merck Sharp & Dohme LLC; SCRI Development Innovations, LLC

Completed

A Study of EDP1503 in Patients With Colorectal Cancer, Breast Cancer, and Checkpoint Inhibitor Relapsed Tumors

Renal Cell Carcinoma | Non Small Cell Lung Cancer | Bladder Cancer | Triple Negative Breast Cancer | Colorectal Cancer Metastatic | GastroEsophageal Cancer | MSI-H

United States, Canada
Rennes University Hospital
Roche Pharma AG; National Research Agency, France

Completed

BMS_PD-L1_onco : Assessment of the PD-L1 Protein as a Biomarker in Oncology and Hematology (BMS_PD-L1)

Hodgkin Lymphoma | Non-small Cell Lung Cancer | Diffuse Large B-cell Lymphoma | Metastatic Breastcancer

France
Emory University
National Cancer Institute (NCI); Pfizer; National Institutes of Health (NIH)

Completed

Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors

Sarcoma | Head and Neck Cancer | Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Colorectal Cancer | Ovarian Cancer | Bladder Cancer | Stage IV Non-Small Cell Lung Cancer | Stage III Pancreatic Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer and other conditions

United States
Instituto Nacional de Cancerologia de Mexico

Recruiting

Nitroglycerin Plus Radiotherapy Versus Conventional Radiotherapy in Patients With Lung Cancer.

Non-small Cell Lung Cancer | Brain Metastases | EGFR Gene Mutation

Mexico
Case Comprehensive Cancer Center

Not yet recruiting

Intestinal & Multivisceral Transplantation for Unresectable Mucinous Carcinoma Peritonei (TRANSCAPE) (TRANSCAPE)

Pseudomyxoma Peritonei | Secondary Malignant Neoplasm of Peritoneum | Secondary Malignant Neoplasm of Retroperitoneum

United States

Clinical Trials on Metastatic Unresectable Sarcoma

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