Clinical Trials on Milignant Gliomas

Total 6295 results

Medical College of Wisconsin

Not yet recruiting

A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas

Glioma | Brain Cancer | Brain Tumor | Glioma Intracranial | Gliomas Benign | Motor Cortex; Lesion
Martin-Luther-Universität Halle-Wittenberg
Merck KGaA, Darmstadt, Germany

Terminated

Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents (HGG-CilMetro)

Gliomas

Germany
Polaris Group

Terminated

Ph 1 Study in Subjects With Tumors Requiring Arginine to Assess ADI-PEG 20 With Pemetrexed and Cisplatin (TRAP)

Glioma | Hepatocellular Carcinoma | Uveal Melanoma | Sarcomatoid Carcinoma | Pleural Mesothelioma Malignant Advanced | Peritoneal Mesothelioma Malignant Advanced | Non-squamous Non-small Cell Lung Carcinoma

United States, United Kingdom
University of Florida
National Cancer Institute (NCI)

Completed

Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme (ATTAC-II)

Glioblastoma | Glioblastoma Multiforme | Malignant Glioma | GBM | Astrocytoma, Grade IV

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); NeoImmuneTech

Terminated

Study of the Effect NT-I7 on CD4 Counts in Patients With High Grade Gliomas

Malignant Glioma | Lymphopenia

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Dexamethasone and Azeliragon for Management of Post-Resection Cerebral Edema in Patients With Glioblastoma

Glioblastoma | Malignant Glioma

United States
Central Hospital, Nancy, France

Completed

Evaluation of the Use of Radiomics in 18F-FDOPA PET Examinations for the Characterization of Gliomas (RADDOPAG)

Study on the Use of Radiomics in Gliomas of Initial Disgnosis

France
Chimerix

Active, not recruiting

ONC201 in Pediatric H3 K27M Gliomas

Diffuse Intrinsic Pontine Glioma | Glioma, Malignant

United States
INSYS Therapeutics Inc

Completed

Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Mixed Oligoastrocytoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Multiple Doses of Neural Stem Cell Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent WHO Grade III Glioma | Recurrent WHO Grade II Glioma | Recurrent Gliosarcoma | Recurrent Anaplastic Astrocytoma | Recurrent Anaplastic Oligoastrocytoma | Recurrent Anaplastic Oligodendroglioma

United States
Beijing Tiantan Hospital

Not yet recruiting

Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant Glioma (CSAγδTBMG)

Medulloblastoma | GBM | DIPG Brain Tumor

China
Indiana University

Terminated

Pilot Study of Cabozantinib for Recurrent or Progressive Central Nervous System Tumors in Children

Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Malignant Brain Tumor

United States
M.D. Anderson Cancer Center

Withdrawn

Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer

Malignant Glioma | Medulloblastoma | Anaplastic Ependymoma | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Atypical Teratoid/Rhabdoid Tumor | Primitive Neuroectodermal Tumor | Choroid Plexus Carcinoma | Recurrent Atypical Teratoid/Rhabdoid Tumor | Malignant Brain Neoplasm | Central Nervous System... and other conditions

United States
Nanfang Hospital, Southern Medical University

Recruiting

Efficacy and Safety of Rivaroxaban in the Prevention of Venous Thromboembolism in Glioma Patients

Glioma, Malignant

China
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Malignant Glioma | WHO Grade 3 Glioma | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Refractory Primary Central Nervous System Neoplasm | Recurrent Childhood Central Nervous System Neoplasm | Recurrent Brain Neoplasm | Recurrent Childhood...

United States
Thomas Jefferson University

Recruiting

Analysis of Cell Count, Viability, and Immunogenicity of Discarded Newly Diagnosed Glioblastoma Tissue or Solid Tumor Tissues

Malignant Solid Neoplasm | Glioblastoma

United States
Northwell Health

Recruiting

Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)

Glioma | Glioblastoma | Brain Cancer | Glioblastoma Multiforme | High Grade Glioma | GBM | Glioma, Malignant | Glioblastoma Multiforme of Brain

United States
National Cancer Institute (NCI)
Children's Oncology Group

Active, not recruiting

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

Refractory Malignant Solid Neoplasm | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Glioma | Recurrent Malignant Solid Neoplasm | Recurrent Medulloblastoma | Recurrent Neuroblastoma and other conditions

United States, Puerto Rico, Australia
Burzynski Research Institute

Withdrawn

Phase 3 Study of ANP Therapy vs. TMZ for Optic Pathway Glioma

Optic Nerve Glioma
Eben Rosenthal
National Cancer Institute (NCI)

Terminated

Cetuximab-IRDye 800CW in Detecting Tumors in Patients With Malignant Glioma Undergoing Surgery

Malignant Glioma | Brain Neoplasm

United States
Dartmouth-Hitchcock Medical Center

Completed

Protocol to Distinguish Tumor Recurrence From Treatment-Related Necrosis in Patients With High Grade Gliomas

Recurrent High Grade Gliomas

United States
National Cancer Institute (NCI)

Recruiting

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

Glioblastoma | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Astrocytoma, Not Otherwise Specified | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Glioblastoma, Not Otherwise Specified

United States, Australia, New Zealand, Canada
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma

Malignant Neoplasms of Eye, Brain and Other Parts of Central Nervous System

United States
Memorial Sloan Kettering Cancer Center
Genentech, Inc.; National Institutes of Health (NIH)

Completed

Bevacizumab, Temozolomide and Hypofractionated Radiotherapy for Patients With Newly Diagnosed Malignant Glioma

Brain Cancer | Malignant Glioma

United States
medac GmbH
IKP

Completed

Clinical Study on 5-aminolevulinic Acid Hydrochloride (5-ALA) for Fluorescence-guided Resection of Malignant Gliomas

Brain Neoplasm
Henry Ford Health System

Recruiting

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

Glioma | Glioblastoma | Astrocytoma | Malignant Glioma of Brain | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | GBM | Malignant Astrocytoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent WHO Grade III Glioma | Recurrent Gliosarcoma | Recurrent Anaplastic Astrocytoma | Recurrent Anaplastic Oligoastrocytoma | Recurrent Anaplastic Oligodendroglioma

United States
Eli Lilly and Company
National Cancer Institute (NCI)

Completed

A Phase I Trial of Enzastaurin (LY317615) in Combination With Carboplatin in Adults With Recurrent Gliomas

Recurrent Gliomas

United States
Phoenix Molecular Imaging

Withdrawn

C11-Sodium Acetate PET/CT Imaging Evaluation in Brain Glioma, Post Therapy Necrosis and Pseudo-progression

Gliomas

United States
Children's Hospital Medical Center, Cincinnati
Genentech, Inc.

Completed

A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas

Diffuse Intrinsic Pontine Glioma | Newly Diagnosed High-Grade Gliomas

United States
M.D. Anderson Cancer Center
DNAtrix, Inc.

Recruiting

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent Gliosarcoma | Recurrent Anaplastic Astrocytoma | IDH1 wt Allele

United States
Andrew B Lassman, MD
Genentech, Inc.; OSI Pharmaceuticals

Completed

EGFR Inhibition Using Weekly Erlotinib for Recurrent Malignant Gliomas

Brain Cancer

United States
Jonsson Comprehensive Cancer Center
National Institutes of Health (NIH)

Completed

Vaccine Therapy in Treating Patients With Malignant Glioma

Brain and Central Nervous System Tumors

United States
San Diego Pacific Oncology & Hematology Associates

Unknown

Radiation Therapy, Temozolomide, Tamoxifen, and Carboplatin in Treating Patients With Malignant Gliomas

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Active, not recruiting

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Ependymoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Glioma | Recurrent Malignant Solid Neoplasm | Recurrent Medulloblastoma | Recurrent... and other conditions

United States, Puerto Rico
National Cancer Institute (NCI)

Active, not recruiting

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

Recurrent Childhood Ependymoma | Advanced Malignant Solid Neoplasm | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Recurrent Neuroblastoma | Recurrent Non-Hodgkin... and other conditions

United States, Puerto Rico
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors

Glioblastoma | Malignant Glioma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Astrocytoma, Grade III | Brain Stem Neoplasms, Malignant | Oligodendroblastoma

United States
Sabine Mueller, MD, PhD
National Cancer Institute (NCI); Dana-Farber Cancer Institute; Mithil Prasad... and other collaborators

Recruiting

ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors (PNOC023)

Glioblastoma | Recurrent Ependymoma | CNS Tumor | Diffuse Midline Glioma (DMG) | Recurrent Malignant Central Nervous System Neoplasm | Spinal Cord Glioma | Central Nervous System Tumor | World Health Organization (WHO) Grade III Glioma

United States, Switzerland
National Cancer Institute (NCI)

Active, not recruiting

Testing the Sequential Combination of the Anti-cancer Drugs Olaparib Followed by Adavosertib (AZD1775) in Patients With Advanced Solid Tumors With Selected Mutations and PARP Resistance, STAR Study

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); American Lebanese Syrian Associated Charities...

Active, not recruiting

INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas

Glioblastoma Multiforme | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | DIPG | High-grade Astrocytoma NOS | CNS Primary Tumor, NOS (Malignant Glioma)

United States
National Cancer Institute (NCI)

Completed

CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIII

Glioblastoma | Brain Cancer | Malignant Glioma | Gliosarcoma

United States
Massachusetts General Hospital
Foundation for Informed Medical Decision Making

Completed

A Pilot Study of Using Video Images in Advance Care Planning in Malignant Glioma Patients

Advanced Brain Cancer

United States
Stanford University
CTI BioPharma; Cephalon

Completed

Phase I Trial of Arsenic Trioxide and Stereotactic Radiotherapy for Recurrent Malignant Glioma

Brain Cancer

United States
Massachusetts General Hospital

Recruiting

NeuroPathways Intervention for Brain Tumor Patients

Glioma | Coping Skills | Malignant Brain Tumor

United States
Rambam Health Care Campus

Unknown

Isolation and Characterization of Cancer Stem Cells Using iFP Technique

Glioma | Pancreatic Cancer | Malignant Neoplasm of Breast

Israel
Massachusetts General Hospital

Not yet recruiting

ASCENT Intervention for Brain Tumor Patients

Glioma | Coping Skills | Distress, Emotional | Malignant Brain Tumor

United States
Virginia Commonwealth University
National Cancer Institute (NCI)

Active, not recruiting

Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma

Glioblastoma | Malignant Glioma | WHO Grade III Glioma | Recurrent Adult Brain Neoplasm

United States
DNAtrix, Inc.

Completed

DNX-2401 (Formerly Known as Delta-24-RGD-4C) for Recurrent Malignant Gliomas

Central Nervous System Diseases | Brain Cancer

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Tumor Tissue Analysis in Patients Receiving Imatinib Mesylate for Malignant Glioma

Brain and Central Nervous System Tumors

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

O(6)-Benzylguanine in Treating Patients With Malignant Glioma

Brain and Central Nervous System Tumors

United States

Clinical Trials on Milignant Gliomas

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