Clinical Trials on Mitochondrial Cytopathies Disorders in Netherlands

Total 3507 results

Maastricht University

Recruiting

Effect and Safety MABs Administration m.3243A>G Mutation Carriers

Mitochondrial Myopathies

Netherlands
Maastricht University

Recruiting

mtDNA Mutation Load Analysis in Mesoangioblasts (MABS05)

Mitochondrial Myopathies

Netherlands
Maastricht University

Completed

MABs Therapy m.3243A>G Mutation Carriers (MABS01)

Mitochondrial Myopathies

Netherlands
Khondrion BV
Radboud University Medical Center

Completed

The KHENERGY Study (KHENERGY)

Mitochondrial Diseases | Mitochondrial Myopathies | MELAS | Mitochondrial Encephalomyopathies | MIDD

Netherlands
Reneo Pharma Ltd

Terminated

An Open Label, Long Term Safety Study of REN001 in Primary Mitochondrial Myopathy Patients (Stride Ahead)

Primary Mitochondrial Myopathy

Spain, Australia, Belgium, Denmark, Canada, United Kingdom, France, Germany, Hungary, Italy, Netherlands, New Zealand
Reneo Pharma Ltd

Completed

An Efficacy and Safety Study of 24 Week Treatment With Mavodelpar (REN001) in Primary Mitochondrial Myopathy Patients (STRIDE)

Primary Mitochondrial Myopathy

United States, Spain, Australia, France, United Kingdom, New Zealand, Denmark, Norway, Czechia, Belgium, Canada, Germany, Hungary, Italy, Netherlands
Stealth BioTherapeutics Inc.

Active, not recruiting

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD) (NuPower)

Mitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Complex I Deficiency | Mitochondrial Pathology | Mitochondrial DNA Depletion | Mitochondrial DNA Mutation | Mitochondrial DNA Deletion | Mitochondrial Metabolism Defect

Spain, United States, Italy, Netherlands, Australia, Germany, Hungary, New Zealand, Norway, United Kingdom
Khondrion BV
Julius Clinical

Completed

The KHENERGYZE Study

Mitochondrial Diseases | Mitochondrial Myopathies | MELAS Syndrome | Mitochondrial Encephalomyopathies | MIDD

Netherlands, Denmark, Germany, United Kingdom
Maastricht University

Terminated

NAD Supplementation Study (NADS)

Aging | Mitochondrial Function

Netherlands
Khondrion BV
Julius Clinical; ProPharma Group; Certara

Completed

The KHENEREXT Study

Mitochondrial Diseases | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Maternally Inherited Diabetes and Deafness (MIDD) | Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS) | Chronic Progressive External Ophthalmoplegia (CPEO)

Netherlands, Denmark, United Kingdom, Germany
Maastricht University
Wageningen University and Research; Top Institute Food and Nutrition; Netherlands...

Terminated

The Effect of Fish Oils With Dairy or Plant Based Lipids on Mitochondrial and Physical, and Cognitive Function, in Elderly Humans

Cognitive Function | Ageing | Physical Function | Mitochondrial Function

Netherlands
Maastricht University Medical Center
Ministry of Education, Culture and Science

Unknown

Human Brown Adipose Tissue and Mitochondrial Respiration

Obesity | Aging | Mitochondrial Metabolism Disorders | Adipose Tissue, Brown

Netherlands
Radboud University Medical Center
Stichting Stofwisselkracht

Recruiting

MItochondrial Diabetes LOw Carb- Diet Study (MIDLOC)

Mitochondrial Diseases | Diabetes-Deafness Syndrome Maternally Transmitted

Netherlands
Khondrion BV
Julius Clinical; ProPharma Group; Europees Fonds voor Regionale Ontwikkeling... and other collaborators

Active, not recruiting

The KHENERGYC Study

Mitochondrial Diseases | MELAS | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Subacute Necrotizing Encephalomyelopathy

Netherlands
Radboud University Medical Center

Completed

Inspiratory Muscle Training in Nemaline Myopathy (NEMTRAIN)

Inspiratory Muscle Training | Nemaline Myopathy

Netherlands
Sanquin-LUMC J.J van Rood Center for Clinical Transfusion...
Leiden University Medical Center

Completed

Insufficient Oxygenation in Septic Patients (INOX-SEPSIS)

Sepsis | Fluid Therapy | Critical Care | Oxygen | Mitochondria

Netherlands
Omeicos Therapeutics GmbH

Recruiting

OMT-28 in Patients With Primary Mitochondrial Disease (PMD) (PMD-OPTION) (PMD-OPTION)

Primary Mitochondrial Disease

Netherlands, Germany, Italy
Sanquin-LUMC J.J van Rood Center for Clinical Transfusion...
Leiden University Medical Center

Completed

Mitochondrial Oxygen Measurement Variability in Critically Ill Patients (INOX Variability Study)

Healthy | Mitochondrial Oxygenation Measurement | Measurement Error

Netherlands
Radboud University Medical Center
UMC Utrecht

Not yet recruiting

The Natural History and Muscle Fatigability of Patients With Congenital Myopathies. (READYCOM)

Centronuclear Myopathy | Nemaline Myopathy | Central Core Disease | Multi-Minicore Disease

Netherlands
Rick Hulskes
Photonics Healthcare B.V., Utrecht, The Netherlands

Completed

Anaesthetic Management Guided by COMET Measurements (AIMED COMET)

Surgical Site Infection | Mitochondrial Oxygenation Measurement

Netherlands
Sanquin-LUMC J.J van Rood Center for Clinical Transfusion...
Erasmus Medical Center; Academisch Medisch Centrum - Universiteit van Amsterdam... and other collaborators

Terminated

Insufficient Cellular Oxygen in ICU Patients With Anaemia (INOX ICU-2)

Anemia | Critical Care | Erythrocyte Transfusion | Oxygen | Mitochondria

Netherlands
University Medical Center Groningen
UMC Utrecht; University of Oxford; Academisch Medisch Centrum - Universiteit... and other collaborators

Completed

Acute Nutritional Ketosis in VLCAD Deficiency

VLCAD Deficiency | Fatty Acid Oxidation Defects

Netherlands
Dynacure

Terminated

Early Phase Human Drug Trial to Investigate Dynamin 101 (DYN101) in Patients ≥ 16 Years With Centronuclear Myopathies (Unite-CNM)

Centronuclear Myopathy

France, Netherlands, United Kingdom, Belgium, Denmark, Germany
Academisch Medisch Centrum - Universiteit van Amsterdam...
Princess Beatrix Muscle Foundation

Recruiting

Add-on Intravenous Immunoglobulins in Early Myositis (TIMEISMUSCLE)

Myositis | Dermatomyositis | Polymyositis | Antisynthetase Syndrome | Immune-Mediated Necrotizing Myopathy | Inflammatory Myopathy, Idiopathic

Netherlands
Santhera Pharmaceuticals

Completed

Patient Reported Outcomes in Friedreich's Ataxia Patients After Withdrawal From Treatment With Idebenone (PROTI) (PROTI)

Friedreich's Ataxia

Netherlands, Austria, Germany, United Kingdom
Chaim Huijser
Levvel

Recruiting

SPACE: a Parent-based Treatment for Pediatric OCD

Obsessive-Compulsive Disorder | Anxiety Disorders and Symptoms | Obsessive-Compulsive Disorder in Children | Obsessive-Compulsive Disorder in Adolescence

Netherlands
University Medical Center Groningen

Completed

Blue Enriched Versus Standard Light Treatment for Seasonal Affective Disorder(SAD)

Seasonal Affective Disorder

Netherlands
UMC Utrecht
Alfasigma S.p.A.; ReumaNederland; Autoimmune Research and Collaboration Hub

Not yet recruiting

Drug Rediscovery for Rare Immune Mediated Inflammatory Diseases (DRIMID)

IgG4-related Disease | Idiopathic Inflammatory Myopathies | Behcet's Disease

Netherlands
AstraZeneca

Completed

Addition of Quetiapine in Obsessive Compulsive Disorder - Westenberg Study

Obsessive Compulsive Disorder

Netherlands
De Viersprong

Not yet recruiting

MBT-early: a Single Case Experimental Design

Borderline Personality Disorder

Netherlands
University of Amsterdam
Academic Center for Trauma and Personality; Arkin Mental Health Care

Enrolling by invitation

The Influence of Treatment Format on Schema Therapy for Borderline Personality Disorder (IST-IGST)

Borderline Personality Disorder

Netherlands
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Pharmacogenetics Informed Tricyclic Antidepressant Dosing (PITA) (PITA)

Depressive Disorder, Major

Netherlands
VU University of Amsterdam

Completed

Acceptance and Commitment Therapy Versus Cognitive Therapy for the Treatment of Major Depressive Disorder

Major Depressive Disorder

Netherlands
University of Groningen
ZonMw: The Netherlands Organisation for Health Research and Development; Lentis... and other collaborators

Unknown

Yoga for Young Women With Depression

Major Depressive Disorder

Netherlands
Accare

Recruiting

HANDS-ON: a Personalized, Brief and Intensive Exposure-based Intervention for Youth With Persistent Anxiety or OCD

Obsessive-Compulsive Disorder | Anxiety Disorders | Obsessive-Compulsive Disorder in Children | Obsessive-Compulsive Disorder in Adolescence

Netherlands
UMC Utrecht

Unknown

Functional MRI of Cognitive Control in Autism

Autism

Netherlands
Utrecht University
De Waag

Recruiting

The Effectiveness of Blended Forensic Ambulant Systemic Therapy (FASTb)

Conduct Disorder | Behavioral Disorder | Antisocial Behavior

Netherlands
Rivierduinen, Centre for Personality disorders...
Erasmus Medical Center

Unknown

Intensified, Inpatient Adaptation of Dialectical Behavior Therapy (DBT) (REDBT)

Borderline Personality Disorder

Netherlands
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effects of a Single-Dose and Repeat-Administration of Intranasal Esketamine on On-Road Driving in Participants With Major Depressive Disorder (DriveSaFe2)

Depressive Disorder, Major

Netherlands
AstraZeneca

Terminated

Efficacy of Quetiapine in Generalised Social Anxiety Disorder

Social Anxiety Disorder

Netherlands
UMC Utrecht
National Institute on Drug Abuse (NIDA); ZonMw: The Netherlands Organisation...

Completed

Impaired Decision-making in Adolescents

Substance-Related Disorders | Adolescent Psychiatry | Antisocial Personality Disorders

Netherlands
UMC Utrecht

Unknown

Magnetic Resonance Imaging of Brain Development in Autism

Autism

Netherlands
University of Amsterdam
Academic Center for Trauma and Personality

Recruiting

Imagery Rescripting as Treatment for Depression

Major Depressive Disorder | Persistent Depressive Disorder

Netherlands
UMC Utrecht
FPC De Kijvelanden, Poortugaal

Terminated

Efficacy of a Triptan in the Treatment of Hostility and Aggression Among Convicts With a Psychiatric Treatment Order

Psychotic Disorders | Antisocial Personality Disorder | Intermittent Explosive Disorder | Impulse Regulation Disorder

Netherlands
Santhera Pharmaceuticals

Completed

Long-Term Safety and Tolerability of Idebenone in Friedreich's Ataxia Patients (MICONOS Extension)

Freidreich's Ataxia

Germany, Netherlands, France, Austria, Belgium
VU University of Amsterdam

Completed

Virtual Reality Exposure Therapy Versus Exposure in Vivo for Social Phobia

Social Anxiety Disorder | Social Phobia

Netherlands
UMC Utrecht

Completed

Magnetic Resonance Imaging in Children and Adolescents With Autism and Multiple Complex Developmental Disorders

Developmental Disabilities | Autism

Netherlands
VU University of Amsterdam
Netherlands Institute for the Study of Crime and Law Enforcement (NSCR)

Not yet recruiting

Feasibility and Acceptability of Problem Management Plus (PM+) for Prisoners in the Netherlands - a Pilot RCT (PROSPER)

Depressive Disorder | Anxiety Disorders | Psychological Distress

Netherlands
UMC Utrecht
ZonMw: The Netherlands Organisation for Health Research and Development

Unknown

Prevention of Oppositional Defiant and Conduct Disorders in Preschool Children

Conduct Disorder | Oppositional Defiant Disorder

Netherlands
GH Research Ireland Limited

Completed

Clinical Study of GH001 in Depression

Depression | Major Depressive Disorder | Treatment Resistant Depression

Netherlands

Clinical Trials on Mitochondrial Cytopathies Disorders in Netherlands

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