Clinical Trials on Mitochondrial DNA Depletion in Switzerland

Total 302 results

Prof. Dr. Jörg Leuppi

Terminated

Inhaled Aviptadil for the Treatment of COVID-19 in Patients at High Risk for ARDS

Covid19 | Corona Virus Infection | ARDS | Aviptadil

Switzerland
University Hospital, Basel, Switzerland

Terminated

Effect of Cobicistat Versus Ritonavir Boosting on the Brain Permeation of Darunavir in HIV-infected Individuals

AIDS-related Dementia Complex

Switzerland
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity Study of the Influenza Vaccine in Adults

Influenza | Orthomyxoviridae Infections

Belgium, Germany, Switzerland
Novartis Vaccines

Completed

Immunogenicity, Safety and Tolerability of Two Doses of Adjuvanted and Non-adjuvanted Swine Origin A/H1N1 Monovalent Influenza Vaccine in Healthy Subjects 18 or More Years of Age

Pandemic Influenza

Switzerland, Belgium, Germany
Novartis Vaccines

Completed

Immunogenicity, Safety and Tolerability of Two Doses of Adjuvanted and Non-adjuvanted Swine Origin A/H1N1 Monovalent Influenza Vaccine in Healthy Subjects 18 or More Years of Age

Pandemic Influenza

Switzerland, Belgium, Germany
University of Lausanne Hospitals

Completed

Physiological Response to Prone Position in COVID-19 Associated Acute Respiratory Distress Syndrome (ARDS)

ARDS | Sars-CoV-2 Infection

Switzerland
University Hospital, Geneva
University Hospital, Basel, Switzerland; Hôpital Fribourgeois; Ospedale Regionale...

Recruiting

Preemptive Use of Convalescent Plasma for High-risk Patients With COVID-19

Covid19 | Old Age; Debility | Immuno-Deficiency

Switzerland
Calmy Alexandra
Oswaldo Cruz Foundation; ANRS, Emerging Infectious Diseases

Recruiting

Assessment of the Efficacy and Safety of Tecovirimat in Patients With Monkeypox Virus Disease (UNITY)

Monkeypox | Mpox

Switzerland, Brazil, Argentina
University of Zurich
Cantonal Hospital of St. Gallen; Triemli Hospital; Kantonsspital Münsterlingen

Completed

Sevoflurane in COVID-19 ARDS (SevCov)

Coronavirus | ARDS, Human

Switzerland
Foundation for Innovative New Diagnostics, Switzerland

Completed

COVID-19 Novel Molecular Point of Care Diagnostics Evaluation

COVID-19 Respiratory Infection

Switzerland, Uganda, United Kingdom
Kinarus AG

Suspended

The KIN-FAST Trial (KIN001 For Accelerated Symptoms Termination) in Non Hospitalized Patients Infected With SARS-CoV-2 (KIN-FAST)

COVID-19

Switzerland, Germany
Calmy Alexandra

Completed

Efficacy of Pragmatic Same-day COVID-19 Ring Prophylaxis for Adult Individuals Exposed to SARS-CoV-2 in Switzerland (COPEP)

Prevention of COVID-19

Switzerland, Brazil
University of Bern
Roche Pharma AG; University of Lausanne; University of Basel; Cantonal Hospital... and other collaborators

Completed

High Dose Ribavirin in the Treatment of Chronic Hepatitis C

Chronic Hepatitis C

Switzerland
GlaxoSmithKline

Active, not recruiting

A Clinical Study to Evaluate Immune Responses to Rabies Vaccine in Adults Who Received Different Primary Rabies Vaccination Regimens

Virus Diseases

Austria, Germany, Switzerland
Novartis Pharmaceuticals

Terminated

Liver Fibrosis in Patients Transplanted for Hepatitis C Receiving Either Cyclosporine Microemulsion or Tacrolimus

Hepatitis C | Liver Transplant

United States, Switzerland
Prof. Dr. Jörg Leuppi

Completed

High Dose Vitamin-D Substitution in Patients With COVID-19: a Randomized Controlled, Multi Center Study (VitCov)

Covid19 | Vitamin D Deficiency | Corona Virus Infection | ARDS | SARS-CoV Infection | Coronavirus

Switzerland
Cytheris SA

Unknown

Dose Escalation Study of Interleukin-7 (IL-7) and Bitherapy in HCV Genotype 1 or 4 Patients Resistant to Bitherapy Alone (Eclipse 2)

Hepatitis C

France, Switzerland, Italy
Cytheris SA

Completed

Dose Escalation Study of IL-7 and Bi-therapy in HCV Patients Resistant After 12 Weeks of Bi-therapy (ECLIPSE 1) (ECLIPSE 1)

Hepatitis C

France, Switzerland, Italy
University Hospital Inselspital, Berne

Completed

TAF for HIV-HBV With Renal Dysfunction

HIV and Hepatitis B Coinfection

Switzerland
Daiichi Sankyo

Active, not recruiting

HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Advanced EGFRm NSCLC After Failure of EGFR TKI Therapy

EGFR L858R | EGFR Exon 19 Deletion | Nonsquamous Non-small Cell Lung Cancer

Korea, Republic of, United States, Netherlands, Spain, United Kingdom, Japan, Austria, Belgium, Italy, France, Taiwan, Germany, Australia, Singapore, China, Hong Kong, Norway, Canada, Poland, Portugal, Switzerland
University Hospital Inselspital, Berne
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Terminated

CorONa Virus edoxabaN ColchicinE (CONVINCE) COVID-19 (CONVINCE)

COVID-19 | SARS-CoV Infection

Belgium, Switzerland, Italy
Calmy Alexandra

Completed

Evaluation of a Simplified Strategy for the Long-term Management of HIV Infection (Simpl'HIV) (Simpl'HIV)

Antiretroviral Therapy | HIV-1-infection | Maintenance Therapy

Switzerland
University of Zurich
University Hospital, Geneva; University Hospital Inselspital, Berne; Centre Hospitalier... and other collaborators

Unknown

Yellow Fever Vaccination Under Low Dose Methotrexate Therapy (MTX_YF)

Dermatologic Disorders | Rheumatic

Switzerland
University Hospital Inselspital, Berne

Completed

Study to Investigate Long-term Pulmonary and Extrapulmonary Effects of COVID-19

COVID-19

Switzerland
Oriol Manuel
University of Zurich; University Hospital, Geneva; University Hospital, Basel... and other collaborators

Completed

Reducing the Burden of Influenza After Solid-Organ Transplantation (STOP-FLU)

Influenza | Organ Transplantation

Switzerland, Spain
University Hospital, Basel, Switzerland
Swiss Multiple Sclerosis Registry

Recruiting

A Study to Assess the Potential Impact of Disease Modifying Therapies on COVID-19 Outcomes and the Antibody Response Following an Infection With SARS-CoV-2 in Patients With Multiple Sclerosis Within the Swiss Multiple Sclerosis Cohort. (MS COVID-19)

Multiple Sclerosis | COVID-19 (Severe Coronavirus Disease 2019)

Switzerland
AbbVie

Completed

Quality of Life Measurement in Treatment Naïve Patients With Hepatitis C Virus (HCV) Genotype 1 (GT1) Suffering From Fatigue and Receiving Ombitasvir, Paritaprevir, and Ritonavir and Dasabuvir (Viekirax®/Exviera®) (HEMATITE)

Chronic Hepatitis C Virus (HCV)

Switzerland
Calmy Alexandra
Janssen-Cilag A.G., Switzerland

Completed

Prospective Evaluation of Etravirine for HIV-infected Patients in Need of Lipid-lowering Drugs (ETRALL)

HIV Infection

Switzerland
University of Zurich
University Hospital, Geneva; University Hospital Inselspital, Berne; University... and other collaborators

Terminated

Enoxaparin for Primary Thromboprophylaxis in Ambulatory Patients With COVID-19

COVID-19 | Pulmonary Embolism, Deep Vein Thrombosis

Switzerland, Germany
University Hospital, Basel, Switzerland
Novartis; Swiss National Science Foundation

Completed

Canakinumab in Patients With COVID-19 and Type 2 Diabetes (CanCovDia)

Coronavirus Infection | Diabetes Mellitus, Type 2

Switzerland
Fondazione Epatocentro Ticino

Recruiting

Swiss Autoimmune Hepatitis Cohort Study

Hepatitis, Autoimmune

Switzerland
ANRS, Emerging Infectious Diseases
University Hospital, Geneva

Recruiting

OPtimisation of Antiviral Therapy in Immunocompromised COVID-19 Patients: a Randomized Factorial Controlled Strategy Trial (OPTICOV)

COVID-19 | Immunodeficiency

Switzerland, France
University Hospital, Basel, Switzerland
Pharming Technologies B.V.

Terminated

Conestat Alfa in the Prevention of Severe SARS-CoV-2 Infection in Hospitalized Patients With COVID-19

Coronavirus Infections

Switzerland, Brazil, Mexico
University of Basel

Recruiting

Cascade Genetic Testing for Hereditary Breast/Ovarian Cancer and Lynch Syndrome in Switzerland (CASCADE)

Lynch Syndrome | Hereditary Breast and Ovarian Cancer

Switzerland
GeNeuro SA

Completed

Temelimab as a Disease Modifying Therapy in Patients With Neuropsychiatric Symptoms in Post-COVID 19 or PASC Syndrome

Post-COVID-19 Syndrome

Switzerland, Italy, Spain
National Institute of Allergy and Infectious Diseases...
HIV Vaccine Trials Network; IPPOX Foundation; CHAVI; MHRP

Completed

Evaluating the Safety and Immune Response to Three Different DNA HIV Vaccines Administered With a MVA-CMDR Boost Vaccine in Healthy, HIV-Uninfected Adults

HIV Infections

United States, Switzerland
National Institute of Allergy and Infectious Diseases...

Completed

Antigenic Competition in HIV Preventive Vaccines

HIV Infections

United States, Peru, Switzerland, Brazil
University Children's Hospital Basel

Completed

Randomised Evaluation of COVID-19 Therapy (RECOVERY) in Children With PIMS-TS in Switzerland (SWISSPED-RECOVERY)

Paediatric Inflammatory Multisystem Syndrome-Temporally Associated With SARS-CoV-2 (PIMS-TS)

Switzerland
Bristol-Myers Squibb
PENTA Foundation

Completed

Post-marketing Safety Surveillance Program in Human Immunodeficiency Virus (HIV)-Infected Children Exposed to Atazanavir in Europe

HIV Infection

Romania, Belgium, Germany, Italy, Spain, Switzerland, United Kingdom
Novartis Vaccines

Completed

Safety and Immunogenicity of 2 Different Vaccination Schedules of Rabies and Japanese Encephalitis Vaccines in Healthy Adult Subjects

Japanese Encephalitis | Rabies

Austria, Germany, Switzerland
Gilead Sciences

Completed

Sofosbuvir/Velpatasvir Fixed Dose Combination in Participants With Chronic Hepatitis C Virus Infection Who Have Received a Liver Transplant

Hepatitis C Virus Infection

Spain, Switzerland, United Kingdom
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Serum Concentrations of a Human Monoclonal Antibody, VRC-HIVMAB075-00-AB (VRC07-523LS), Administered in Multiple Doses and Routes to Healthy, HIV-uninfected Adults

HIV Infections

United States, Switzerland
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome

Completed

A Study of Valacyclovir Hydrochloride in the Prevention of Life-Threatening Cytomegalovirus Disease in HIV-Infected Patients

HIV Infections | Cytomegalovirus Infections

United States, Canada, Italy, United Kingdom, Australia, Denmark, France, Germany, Sweden, Switzerland
Hoffmann-La Roche

Completed

Efficacy and Safety Study of Pegasys in the Treatment of Chronic Hepatitis B

Chronic Hepatitis B

China, Korea, Republic of, Taiwan, Germany, United States, Singapore, Switzerland, Canada, Puerto Rico, Thailand, Israel, France, New Zealand, Poland, United Kingdom, Brazil, Australia
Hoffmann-La Roche

Completed

VICTOR Study - A Study of Valcyte (Valganciclovir po) Compared to Ganciclovir iv in Patients With Cytomegalovirus (CMV) Disease Who Are Solid Organ Transplant Recipients

Cytomegalovirus Infections

Spain, Australia, Ireland, India, Italy, Canada, Belgium, Switzerland, Estonia, Austria, United Kingdom, Brazil, Mexico, Norway, Latvia, Turkey, Croatia, Serbia, Poland, New Zealand, Venezuela
ViiV Healthcare
GlaxoSmithKline

Completed

Fosamprenavir Expanded Access

Infection, Human Immunodeficiency Virus

Switzerland
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Immune Response to Three HIV Vaccine Schedules in Healthy, HIV-Uninfected Adults

HIV Infections

United States, Switzerland
Olatec Therapeutics LLC
CTI Clinical Trial and Consulting Services

Terminated

Safety and Efficacy of Dapansutrile for Treatment of Moderate COVID-19 Symptoms and Evidence of Early Cytokine Release Syndrome

Covid19 | Cytokine Release Syndrome

United States, Switzerland
Cantonal Hospital of St. Gallen
Swiss National Science Foundation; Swiss HIV Cohort Study

Terminated

HIV - Monotherapy in Switzerland (MOST-ch) (MOST)

HIV Infections

Switzerland
Boehringer Ingelheim

Completed

4 Week Combination of BI 207127 NA With Peg-IFN and Ribavirin in Chronic HCV Patients

Hepatitis C, Chronic

France, Germany, Switzerland

Clinical Trials on Mitochondrial DNA Depletion in Switzerland

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Vietnam

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations