Clinical Trials on Mitochondrial Diseases in United Kingdom

Total 147212 results

Olawuyi Racett Nigeria Ltd

Completed

Medlink for Diagnosing of Diabetes Mellitus, COPD, CHF, Myasthenia Gravis and Hypertension (Medlink)

Hypertension | Diabetes Mellitus | Chronic Obstructive Pulmonary Disease | Myasthenia Gravis | Congestive Heart Failure

United Kingdom
University of Leicester
University Hospitals, Leicester

Recruiting

Tissue Models for Liver Disease (TIMOLD)

Liver Diseases

United Kingdom
University Hospitals Coventry and Warwickshire...
University of Hull; Wake Forest University Health Sciences; University of Warwick and other collaborators

Completed

High Intensity Interval Training in UK Cardiac Rehabilitation Programmes (HIIT-or-MISS)

Coronary Disease

United Kingdom
Cordis Corporation
Conor Medsystems

Completed

A Randomized, Multi-Center Study of the Pimecrolimus-Eluting and Pimecrolimus/Paclitaxel-Eluting Coronary Stent Systems (GENESIS)

Coronary Disease

United Kingdom
GlaxoSmithKline
ICON plc

Completed

FF/UMEC/VI Inhaler: Qualitative Analysis and Subject Preference Survey

Pulmonary Disease, Chronic Obstructive

United Kingdom
Imperial College London
Boehringer Ingelheim

Completed

Airway Effects of Tiotropium in Patients With COPD

COPD | LUNG DISEASES, OBSTRUCTIVE

United Kingdom
GlaxoSmithKline

Completed

Optimising the Propranolol Block Model

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of the Dry Powder Formulation of GSK2269557 in Healthy Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

Study to Investigate the Effect of Formoterol vs Salmeterol on Small Airways Physiological Parameters in COPD Patients (Imperial)

Pulmonary Disease, Chronic Obstructive

United Kingdom
Imperial College London
University of Nottingham; University College, London; University of Sheffield; Medical... and other collaborators

Recruiting

The UK Interstitial Lung Disease Long-COVID19 Study (UKILD-Long COVID): Understanding the Burden of Interstitial Lung Disease in Long COVID. (UKILD)

Interstitial Lung Disease | SARS-CoV-2 Infection

United Kingdom
Imperial College London

Completed

Singing for Health: Improving Experiences of Lung Disease (SHIELD Trial) (SHIELD)

COPD

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Unknown

Impact of Isolation in Patients With IBD During the COVID-19 Crisis

Inflammatory Bowel Diseases

United Kingdom
Mitsubishi Tanabe Pharma Corporation

Terminated

Safety and Tolerability Study of MCI-196

Chronic Kidney Disease | Hyperphosphatemia | Paediatric | Not on Dialysis

United Kingdom
RwHealth
Northern Care Alliance NHS Foundation Trust; Alnylam Pharmaceuticals

Not yet recruiting

RWE-based Treatment Patterns and Outcomes in CIDP

Hereditary Amyloidosis | Guillain-Barre Syndrome | Chronic Inflammatory Demyelinating Polyneuropathy

United Kingdom
University of Edinburgh

Completed

Interaction of Apelin and Angiotensin in the Human Forearm Circulation

Heart Disease | Vasodilation

United Kingdom
University of Leicester
University Hospitals, Leicester

Active, not recruiting

Study of Hospitalised Patients With Acute Respiratory Conditions (CHESTY)

Pneumonia | Asthma | COPD Exacerbation Acute | Acute Respiratory Disease

United Kingdom
Barts & The London NHS Trust

Completed

Vitamin D, Chronic Kidney Disease (CKD) and the Microcirculation

Vitamin D Deficiency | Chronic Kidney Disease

United Kingdom
Millennium Pharmaceuticals, Inc.

Completed

Immune Response to Systemic and Mucosal Antigenic Challenge in the Presence of Vedolizumab

Inflammatory Bowel Disease

United Kingdom
Portsmouth Hospitals NHS Trust

Completed

Investigation of Inflammacheck to Measure Exhaled Breath Condensate Hydrogen Peroxide in Respiratory Conditions (VICTORY)

Respiratory Disease

United Kingdom
King's College Hospital NHS Trust
National Institute for Health Research, United Kingdom

Completed

PrEscription of Intra-Dialytic Exercise to Improve quAlity of Life in Patients With Chronic Kidney Disease (PEDAL)

End-Stage Kidney Disease

United Kingdom
iECURE, Inc.

Recruiting

An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of Age With Neonatal Onset OTC Deficiency (OTC-HOPE)

Urea Cycle Disorders, Inborn | Ornithine Transcarbamylase Deficiency | Ornithine Transcarbamylase Deficiency Disease | Ornithine Carbamoyltransferase Deficiency (Disorder)

United Kingdom
Leeds Beckett University

Completed

Effects of a Single Day of Mixed Macronutrient Overfeeding on Energy Balance and Metabolic Responses

Metabolic Disease | Appetitive Behavior

United Kingdom
St George's, University of London
University College London Hospitals

Unknown

Effect of Orthoses and Underfoot Vibration on Balance in Neuropathy

Peripheral Neuropathy | CMT - Charcot-Marie-Tooth Disease | Hereditary Peripheral Neuropathy | CMT1A

United Kingdom
University College, London

Unknown

Melatonin for Nocturia in Parkinson's Disease

Parkinson's Disease | Nocturia

United Kingdom
Hoffmann-La Roche

Completed

A Study to Evaluate the Effect of Aleglitazar on Cardiac Energetics and Function in Patients With Type 2 Diabetes Mellitus and no History of Coronary Artery Disease

Diabetes Mellitus Type 2

United Kingdom
Imperial College London
Cambridge University Hospitals NHS Foundation Trust; Guy's and St Thomas' NHS... and other collaborators

Active, not recruiting

Genetic Determinants of Kawasaki Disease

Kawasaki Disease | Atypical Kawasaki Disease

United Kingdom
Orphalan

Completed

Study Comparing Once Daily Dose of 900mg of TETA 4HCL Against Cuprior® (450mg Trientine Base, Twice Daily).

Wilson's Disease

United Kingdom
Imperial College London
Guy's and St Thomas' NHS Foundation Trust; Liverpool University Hospitals NHS... and other collaborators

Recruiting

Coronary Sinus Reducer Implantation in Patients With Ischaemia and Non-obstructed Coronary Arteries and Coronary Microvascular Dysfunction. (REMEDY-PILOT)

Coronary Disease | Angina Pectoris | Refractory Angina | Microvascular Angina | Microvascular Coronary Artery Disease

United Kingdom
Bristol-Myers Squibb

Completed

A Study to Evaluate BMS-986141 Added on to Aspirin or Ticagrelor or the Combination, on Thrombus Formation in a Thrombosis Chamber Model in Participants With Stable Coronary Artery Disease and Healthy Participants

Coronary Artery Disease | Healthy Participants

United Kingdom
Imperial College London
GlaxoSmithKline

Completed

I2PETHV - Imidazoline2 Binding Site in Healthy Volunteers (I2PETHV)

Alzheimer Disease | Healthy Volunteers | Molecular Imaging

United Kingdom
University of Edinburgh
NHS Lothian

Active, not recruiting

Prospective Validation of the CoDE-HF Algorithm for the Diagnosis of Acute Heart Failure (ProVa CoDE-HF)

Diagnosis | Acute Heart Failure

United Kingdom
Hoffmann-La Roche

Completed

A Study to Investigate the Pharmacokinetics, Pharmacodynamic Effects, Safety and Tolerability of Repeated Dosing of RO5459072 in Volunteers With Celiac Disease

Celiac Disease

United Kingdom
ResMed
Royal Brompton & Harefield NHS Foundation Trust

Withdrawn

Autotitrating Versus Standard Non-invasive Ventilation (NIV) in Acute Exacerbation of Respiratory Failure

Chronic Obstructive Pulmonary Disease | Respiratory Failure | Obesity Hypoventilation Syndrome | Neuromuscular Disease | Chest Wall Disorder

United Kingdom
GlaxoSmithKline

Completed

PK Study of IV Formulation of GW856553

Cardiovascular Disease

United Kingdom
Imperial College London
Millennium Pharmaceuticals, Inc.

Completed

Cigarette Smoke Nasal and Whole Blood Challenge in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Lung Diseases, Obstructive

United Kingdom
University of Edinburgh
British Heart Foundation; Life Molecular Imaging SA

Completed

18F-GP1 PET-CT to Detect Bioprosthetic Aortic Valve Thrombosis

Aortic Valve Disease | Thrombosis Cardiac

United Kingdom
University of Nottingham
Nottingham University Hospitals NHS Trust; University of Salerno

Completed

MAgnetic Resonance Imaging in COeliac Disease (MARCO)

Celiac Disease | Gluten Enteropathy | Coeliac Disease | Celiac Sprue

United Kingdom
Manchester University NHS Foundation Trust

Completed

The Use of Novel Diagnostic Tools to Increase Detection of Early Fibrosis in Cystic Fibrosis Related Liver Disease to Improve Clinical Management

Cystic Fibrosis | Liver Fibroses | Cystic Fibrosis Liver Disease

United Kingdom
Queen's University, Belfast

Completed

Developing an Arts-based Intervention for Patients With End-stage Kidney Disease Whilst Receiving Haemodialysis

Feasibility Study | End Stage Renal Disease on Dialysis (Diagnosis)

United Kingdom
King's College London

Recruiting

The Living With a Long-Term Condition Study (LTC)

Liver Diseases | Heart Diseases | Heart Failure | Stroke | Cerebrovascular Disorders | Epilepsy | Pain | Multiple Sclerosis | Hypertension | Obesity | Diabetes | Cancer | Arthritis | Osteoarthritis | Rheumatoid Arthritis | Parkinson Disease | Migraine | Hepatitis | Atrial Fibrillation | Asthma | Endometriosis | Dementia | Fibromyalgia | Celiac... and other conditions

United Kingdom
University College, London
London School of Hygiene and Tropical Medicine; Brighton & Sussex Medical School

Unknown

Depression and Anxiety in the Aetiology and Prognosis of Specific Cardiovascular Disease Syndromes: a CALIBER Study

Depression | Coronary Disease | Cardiovascular Disease | Anxiety

United Kingdom
University College London Hospitals
Kingston University; Charcot Marie Tooth United Kingdom

Completed

BALTiC Study: A Feasibility Analysis of Home Based BALance Training in People With Charcot-Marie-Tooth Disease (BALTiC)

Charcot-Marie-Tooth Disease, Type IA

United Kingdom
Manchester University NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

Manchester Antenatal Vascular Service (MAViS)

Vascular Disease

United Kingdom
NHS Greater Glasgow and Clyde
University of Glasgow

Unknown

The SaeboGlove Evaluation Trial (T-SET)

Cardiovascular Diseases | Vascular Diseases | Stroke | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Cerebral Vascular Disorder

United Kingdom
Manchester University NHS Foundation Trust

Recruiting

Motivations and Barriers to Participating in Ophthalmology Research Projects

Eye Diseases

United Kingdom
King's College London
King's College Hospital NHS Trust

Terminated

Low-dose IL-2 for Treg Expansion and Tolerance (LITE) (LITE)

Liver Diseases | Transplantation

United Kingdom
University College, London

Unknown

HepCare: The Effectiveness of Community Based Interventions With Peer Support to Improve Case Detection, Carry Out Pre-treatment Assessments and Assist Underserved Populations Through HCV Treatment

Hepatitis C | Infectious Disease

United Kingdom
Barts & The London NHS Trust

Unknown

Preventing Pain After Heart Surgery

Pain | Neuropathic Pain | Hyperalgesia | Chronic Illness

United Kingdom
University of Edinburgh
British Heart Foundation

Completed

Determining the Mechanism of Myocardial Injury and Role of Coronary Disease in Type 2 Myocardial Infarction (DEMAND-MI)

Myocardial Ischemia | Myocardial Injury | Myocardial Infarction, Acute

United Kingdom
University of Nottingham
Mediplus Ltd UK; Enteric healthcare technology Co-operative

Completed

Evaluation of 'Melody' Paracentesis Device for Ascites Therapy (EMPATHY)

Ascites Hepatic | Cirrhosis and Chronic Liver Disease

United Kingdom

Clinical Trials on Mitochondrial Diseases in United Kingdom

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