Clinical Trials on Mitochondrial Diseases in United Kingdom

Total 146859 results

University of Edinburgh
NHS Lothian; Chief Scientist Office of the Scottish Government

Completed

Gap Junction Potentiation of Endothelial Function With Rotigaptide

Heart Disease | Vascular Disease

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
Merck Sharp & Dohme LLC; Pfizer; AbbVie; CORE; Napp Pharmaceuticals Limited

Unknown

Personalising Anti-TNF Therapy in Crohns Disease (PANTS) (PANTS)

Crohn Disease

United Kingdom
University of Nottingham

Active, not recruiting

Phenotyping of Adult Crohn's Focusing on Sarcopenia (PACS)

Inflammatory Bowel Diseases | Sarcopenia | Crohn Disease | Digestive System Disease | Nutrition, Healthy | Protein Malabsorption

United Kingdom
Imperial College London
British Heart Foundation

Completed

Investigation of Leukocyte Trafficking Into Skin Blisters During Cardiopulmonary Bypass

Angina Pectoris | Ischemic Heart Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

Specialist Dietetic Intervention in Malnourished Patients With Fibrotic ILD: a Randomised Controlled Pilot Trial (DT-ILD)

Interstitial Lung Disease

United Kingdom
University of Birmingham
Salford Royal Foundation Trust

Recruiting

Sputum Colour Charts to Guide Antibiotic Self-treatment of Acute Exacerbation of COPD (Colour COPD)

Pulmonary Disease, Chronic Obstructive

United Kingdom
Imperial College Healthcare NHS Trust
Nottingham University Hospitals NHS Trust; Barts & The London NHS Trust; Hospital... and other collaborators

Completed

Ripple Mapping Guided Ablation of Ischaemic Ventricular Tachycardia. (RIPPLE-VT)

Ischemic Heart Disease | Ventricular Tachycardia

United Kingdom
GlaxoSmithKline

Completed

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GSK3915393 in Healthy Participants and to Evaluate the Interaction Between GSK3915393 and Grapefruit Juice and Itraconazole

Celiac Disease | Coeliac Disease

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Case Finding for Coeliac Disease Using a Point of Care Test in a Pharmacy Setting

Coeliac Disease

United Kingdom
Mitsubishi Tanabe Pharma Corporation

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of MT-1303 in Subjects With Inflammatory Bowel Disease

Inflammatory Bowel Disease

United Kingdom
Research in Real-Life Ltd
Sanofi

Completed

Handling Inhalers - Technique Error Comparison (HI-TEC) (HI-TEC)

Pulmonary Disease, Chronic Obstructive | Asthma

United Kingdom
Imperial College London

Completed

Characteristics That Identify Exacerbation Risk Following Colds in COPD Patients

Chronic Obstructive Pulmonary Disease

United Kingdom
Synergy Spine Solutions
MCRA

Not yet recruiting

Post-Market Data Collection to Evaluate the Performance of the Synergy Disc®

Cervical Degenerative Disc Disease

United Kingdom
University of Nottingham

Completed

The Effect of n-3 Polyunsaturated Fatty Acid Supplements in Patients With Non-alcoholic Fatty Liver Disease

Non-alcoholic Fatty Liver Disease

United Kingdom
University of Southampton
University of Nottingham; Nottingham University Hospitals NHS Trust; East Kent... and other collaborators

Recruiting

Aspirin to Target Arterial Events in Chronic Kidney Disease (ATTACK)

Cardiovascular Diseases | Chronic Kidney Diseases | Bleeding

United Kingdom
AstraZeneca

Completed

A Study to Estimate the Effect of AZD5718 on the Pharmacokinetics (What Does the Body Does to the Drug) of Rosuvastatin to Measure the Relative Bioavailability (the Extent to Which a Drug or Other Substance Becomes Available to the Body) of AZD5718 Oral Suspension vs AZD5718 Immediate Release Tablet

High Risk Coronary Artery Disease

United Kingdom
University College, London
London School of Hygiene and Tropical Medicine

Unknown

Prognostic Models for People With Stable Coronary Artery Disease

Stable Coronary Artery Disease

United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

Safety and Tolerability of Inhaled CHF 6001 in Healthy Volunteers (HV)

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
AstraZeneca

Completed

A First Time in Man Study to Asses the Safety and Tolerability of AZD7624 in Healthy Subjects

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
King's College London

Unknown

Donepezil and Memantine in Moderate to Severe Alzheimer's Disease (DOMINO-AD)

Moderate to Severe Alzheimer's Disease

United Kingdom
University of Oxford
National Health and Medical Research Council, Australia; Merck Sharp & Dohme... and other collaborators

Completed

Study of Heart and Renal Protection (SHARP)

Kidney Disease, Chronic

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Intrinsic PEEP and Laryngeal Aperture in COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council

Completed

Is the Short Physical Performance Battery a Useful Outcome Measure in Chronic Obstructive Pulmonary Disease

Lung Diseases | Disease Progression | Lung Diseases, Obstructive | Pulmonary Disease, Chronic Obstructive | Pulmonary Emphysema | Bronchitis, Chronic

United Kingdom
Imperial College London

Withdrawn

Systemic Endothelial Abnormalities in COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
London School of Hygiene and Tropical Medicine
University College, London; British Medical Research Council

Completed

Myocardial Infarction as the First Manifestation of Coronary Heart Disease: Rates of Heralded and Unheralded Myocardial Infarction

Myocardial Infarction

United Kingdom
UCB Pharma SA

Terminated

Sleep Efficiency Assessed by Polysomnography (PSG Sleep Lab Testing) in Advanced Parkinson's Disease (REFRESH-PD)

Advanced Idiopathic Parkinson's Disease

United Kingdom
GlaxoSmithKline

Completed

Method Validation Study to Explore the Sensitivity of SenseWear Armband Gecko for Measuring Physical Activity in Subjects With Chronic Obstructive Pulmonary Disease (COPD) & Asthma

Pulmonary Disease, Chronic Obstructive

United Kingdom
University of Chester

Completed

Effect of Vitamin D3 Supplementation on Cardiometabolic Risk

Cardiovascular Disease | Diabetes | Bone Disease

United Kingdom
London School of Hygiene and Tropical Medicine
University College, London

Completed

Cohort Study of Clopidogrel and Proton Pump Inhibitors

Coronary Heart Disease | Acute Coronary Syndrome | Gastrointestinal Hemorrhage | Drug Interactions | Clopidogrel | Proton Pump Inhibitors

United Kingdom
University of Edinburgh
European Research Council

Recruiting

Genetic Analysis to Predict the Development of Paget's Disease (GAPDPD)

Paget Disease | Paget Disease of Bone

United Kingdom
Belfast Health and Social Care Trust
Bristol Royal Infirmary; Royal Infirmary of Edinburgh; Golden Jubilee National...

Unknown

DISsection RE-entry Evaluation With Absorb Bioresorbable Vascular Scaffolds in CTO. (DISCRETE-CTO)

Coronary Artery Disease

United Kingdom
King's College London
Medical Research Council

Recruiting

The Mind-Body IBD Study: Understanding the Mind-body Connection in IBD

Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis | Crohn Colitis

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; King's College Hospital NHS Trust

Recruiting

Predicting the Risk of Non-culprit Coronary Artery Disease After a Heart Attack (OCT-RISK)

Coronary Artery Disease | ST Elevation Myocardial Infarction | Ischemic Heart Disease

United Kingdom
University College, London
Medical Research Council; Alcohol Research UK

Completed

Alcohol Consumption and Coronary Heart Disease Onset

Coronary Heart Disease

United Kingdom
Derek Richards

Terminated

iCBT for Long-term Conditions in IAPT

Depression | Diabetes | Chronic Pain | Anxiety | COPD | CHD - Coronary Heart Disease

United Kingdom
London School of Economics and Political Science
University College, London; Bambino Gesù Hospital and Research Institute; German...

Completed

Evaluation of Image-Based Modelling on Clinical Decisions in Coarctation of the Aorta

Cardiovascular Disease | Congenital Heart Disease | Aortic Coarctation

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Improving Phosphate Control in Children With CKD (IMPACT)

Chronic Kidney Diseases | Hyperphosphatemia | Chronic Kidney Disease-Mineral and Bone Disorder | Pediatric Kidney Disease | CKD-MBD

United Kingdom
Imperial College London
Medical Research Council; Imperial College Healthcare NHS Trust

Completed

Transtympanic Gentamicin vs. Steroids in Refractory Meniere's Disease

Meniere's Disease

United Kingdom
Swansea Bay University Health Board

Recruiting

The POST-ACS Study

Coronary Artery Disease | Diabetes Mellitus | Acute Coronary Syndrome

United Kingdom
NHS Lothian
University of Edinburgh

Completed

Kidney Recovery After Acute Kidney Injury - Longitudinal Study (KRAKIL)

Chronic Kidney Diseases | Acute Kidney Injury

United Kingdom
University of Oxford

Recruiting

Defining Circadian Metabolism in Non-alcoholic Fatty Liver Disease (DECIMAL)

NAFLD

United Kingdom
University Hospital Birmingham NHS Foundation Trust

Recruiting

A Systems Biology Approach for Identification of Host and Microbial Mechanisms and Druggable Targets for the Treatment of PSC-IBD (PSC-Vanc)

Inflammatory Bowel Diseases | Primary Sclerosing Cholangitis

United Kingdom
Neurophth Therapeutics Inc

Active, not recruiting

Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND4 Mutations

Leber Hereditary Optic Neuropathy (LHON)

United States
Imperial College London

Completed

Macrophage Phagocytosis in COPD

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United Kingdom
Imperial College London
AstraZeneca

Withdrawn

Effect of Symbicort on HAT and HDAC in Sputum Macrophages of COPD

Chronic Obstructive Pulmonary Disease (COPD) | Age Matched Healthy Volunteers (Non-smokers)

United Kingdom
Manchester University NHS Foundation Trust

Not yet recruiting

Oxygen-enhanced Magnetic Resonance Imaging (OE-MRI) of the Heart: A Feasibility Study (OE-MRI)

Coronary Artery Disease

United Kingdom
Queen Mary University of London

Recruiting

Different Surgical Modalities in the Treatment of Periodontitis

Chronic Periodontitis

United Kingdom
University College, London

Completed

Evaluation of CTCA in Assessing Plaque Pathology and Physiology

Coronary Artery Disease

United Kingdom
Imperial College London

Completed

Isoflavones and the Coronary Circulation in Men and Women With Coronary Artery Disease

Coronary Artery Disease

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
AstraZeneca

Completed

STEEL Percutaneous Coronary Intervention (STEEL-PCI)

Coronary Artery Disease

United Kingdom

Clinical Trials on Mitochondrial Diseases in United Kingdom

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