Clinical Trials on Mitochondrial Disorders in Italy

Total 5964 results

Stealth BioTherapeutics Inc.

Active, not recruiting

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD) (NuPower)

Mitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Complex I Deficiency | Mitochondrial Pathology | Mitochondrial DNA Depletion | Mitochondrial DNA Mutation | Mitochondrial DNA Deletion | Mitochondrial Metabolism Defect

Spain, United States, Italy, Netherlands, Australia, Germany, Hungary, New Zealand, Norway, United Kingdom
Stealth BioTherapeutics Inc.

Terminated

A Trial to Evaluate Safety and Efficacy of Elamipretide Primary Mitochondrial Myopathy Followed by Open-Label Extension (MMPOWER-3)

Primary Mitochondrial Myopathy

United States, Germany, Canada, Italy, United Kingdom, Denmark, Hungary
University of Catania

Completed

Evaluation of the Effects of Semen Incubation With ANDROSITOL®DGN on Sperm Motility and Mitochondrial Membrane Potential (Androsi-Test)

Asthenozoospermia | Mitochondrial Damage

Italy
Reneo Pharma Ltd

Terminated

An Open Label, Long Term Safety Study of REN001 in Primary Mitochondrial Myopathy Patients (Stride Ahead)

Primary Mitochondrial Myopathy

Spain, Australia, Belgium, Denmark, Canada, United Kingdom, France, Germany, Hungary, Italy, Netherlands, New Zealand
Reneo Pharma Ltd

Completed

An Efficacy and Safety Study of 24 Week Treatment With Mavodelpar (REN001) in Primary Mitochondrial Myopathy Patients (STRIDE)

Primary Mitochondrial Myopathy

United States, Spain, Australia, France, United Kingdom, New Zealand, Denmark, Norway, Czechia, Belgium, Canada, Germany, Hungary, Italy, Netherlands
Omeicos Therapeutics GmbH

Recruiting

OMT-28 in Patients With Primary Mitochondrial Disease (PMD) (PMD-OPTION) (PMD-OPTION)

Primary Mitochondrial Disease

Netherlands, Germany, Italy
Stealth BioTherapeutics Inc.

Completed

An Observational Study of Patients With Primary Mitochondrial Disease (SPIMM-300) (RePOWER)

Primary Mitochondrial Disease

United States, Spain, Germany, Australia, Canada, Denmark, Hungary, Italy, United Kingdom
IRCCS San Raffaele
Azienda Socio Sanitaria Territoriale della Valle Olona

Recruiting

Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis

Multiple Sclerosis

Italy
PTC Therapeutics

Enrolling by invitation

A Safety Study for Previously Treated Vatiquinone (PTC743) Participants With Inherited Mitochondrial Disease

Inherited Mitochondrial Disease

United States, France, Spain, United Kingdom, Italy, Poland, Japan
Azienda Policlinico Umberto I

Completed

A Phase IIa Trial to Test Safety and Efficacy Interferon Gamma Treatment in Elevating Frataxin Levels in FRDA Patients

Friedreich Ataxia

Italy
Tisento Therapeutics

Not yet recruiting

A Phase 2b Study of Zagociguat in Patients With MELAS (PRIZM)

Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)

United States, Australia, Italy, Germany, Canada, United Kingdom
LMU Klinikum
University of Pisa; German Federal Ministry of Education and Research; European...

Recruiting

Global Registry and Natural History Study for Mitochondrial Disorders

Mitochondrial Diseases | MDS | Mitochondrial Myopathies | MELAS Syndrome | MIDD | Kearns-Sayre Syndrome | MERRF Syndrome | Barth Syndrome | Leigh Syndrome | MNGIE | LHON | Pearson Syndrome | NARP Syndrome | Coenzyme Q10 Deficiency | SANDO | SCAE | MIRAS | CPEO

Austria, Germany, Italy
Federico II University

Completed

Efficacy of Epoetin Alfa in Patients With Friedreich's Ataxia

Friedreich's Ataxia

Italy
IRCCS Eugenio Medea
University of Rome Tor Vergata

Completed

Safety and Efficacy of Etravirine in Friedreich Ataxia Patients (FAEST1)

Friedreich Ataxia

Italy
Federico II University
Friedreich's Ataxia Research Alliance; Associazione Italiana per la lotta alle...

Completed

Efficacy Study of Epoetin Alfa in Friedreich Ataxia (FRIEMAX)

Friedreich Ataxia

Italy
ApoPharma

Completed

A Study Investigating the Long-term Safety and Efficacy of Deferiprone in Patients With Friedreich's Ataxia

Friedreich's Ataxia

Belgium, France, Italy, Spain
Fondazione Telethon

Completed

Use of Phenylbutyrate Therapy for Patients With Pyruvate Dehydrogenase Complex Deficiency. (TIGEM2-PDH)

Pyruvate Dehydrogenase Complex Deficiency

Italy
H. Lundbeck A/S

Completed

Safety Study of Carbamylated Erythropoietin to Treat Patients With the Neurodegenerative Disorder Friedreich's Ataxia

Friedreich's Ataxia

Germany, Austria, Italy
ApoPharma

Completed

A Study Investigating the Safety and Tolerability of Deferiprone in Patients With Friedreich's Ataxia

Friedreich's Ataxia

Canada, Australia, Belgium, France, Italy, Spain
RWTH Aachen University
Assistance Publique - Hôpitaux de Paris

Withdrawn

Study of the Efficacy and Safety of Nicotinamide in Patients With Friedreich Ataxia (NICOFA)

Friedreich Ataxia

Spain, Italy, Austria, Germany, United Kingdom, France
Institute of Neuroscience, Florence, Italy

Completed

Ondansetron in Treatment Resistant Obsessive Compulsive Disorder (OCD)

Obsessive Compulsive Disorder

Italy
LMU Klinikum
Seventh Framework Programme; NBIA Alliance

Recruiting

TIRCON International NBIA Registry (TIRCON)

Neurodegeneration With Brain Iron Accumulation (NBIA) | Pantothenate Kinase-associated Neurodegeneration (PKAN) | Aceruloplasminemia | Beta-Propeller Protein-Associated Neurodegeneration (BPAN) | Mitochondrial Membrane Protein Associated Neurodegeneration (MPAN) | Fatty Acid Hydroxylase-associated... and other conditions

Canada, Czechia, Germany, Italy, Netherlands, Poland, Serbia, Spain
Azienda Ospedaliero-Universitaria Careggi

Recruiting

Sumor as Adjuvant Therapy in Treatment-resistant Major Depression (SUSCA)

Major Depressive Disorder

Italy
Istituto Auxologico Italiano

Recruiting

Phenotypisation of Sleep Pattern in Hypertensive Patients With Non Dipper Pattern (INTO-DIP)

Hypertension | Sleep Disorder

Italy
Ospedale San Raffaele
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico; Ministry of Health...

Recruiting

Improving Health Care in Major Depressive Disorder (DepType)

Major Depressive Disorder

Italy
Istituto per la Ricerca e l'Innovazione Biomedica
Messina, Italy

Recruiting

Advanced Social Relations Training

Autism Spectrum Disorder | Autism

Italy
Istituto per la Ricerca e l'Innovazione Biomedica

Recruiting

Applied Behavior Analysis With Technologies

Autism Spectrum Disorder | Autism

Italy
IRCCS Centro Neurolesi "Bonino-Pulejo"

Recruiting

Multisensory Room in Autism Spectrum Disorder

Autism Spectrum Disorder

Italy
Istituto per la Ricerca e l'Innovazione Biomedica
Comune di Messina

Recruiting

Group Intervention on Theory of Mind in Children With Autism Spectrum Disorder.

Autism Spectrum Disorder

Italy
Istituto per la Ricerca e l'Innovazione Biomedica
Comune di Messina

Recruiting

Social Relations Training for Children With ASD

Autism Spectrum Disorder | Autism

Italy
Istituto per la Ricerca e l'Innovazione Biomedica
Comune di Messina

Recruiting

Food Selectivity Protocol for Children With Autism Spectrum Disorders

Autism Spectrum Disorder

Italy
Istituto per la Ricerca e l'Innovazione Biomedica
Comune di Messina

Not yet recruiting

Comparing Imitation and Stereotyped Behaviors in Autistic Children: Robots vs. Human Operators

Autism Spectrum Disorder | Autism

Italy
Istituto per la Ricerca e l'Innovazione Biomedica
Fondazione di Comunità di Messina onlus

Recruiting

Group Intervention on Executive Function in Children With Autism Spectrum Disorder

Autism Spectrum Disorder | Autism

Italy
IRCCS Centro Neurolesi "Bonino-Pulejo"
Regione Sicilia

Recruiting

Combination of Predictive Biomarkers to Increase Diagnostics Efficiency of Autism Spectrum Disorder

Autism Spectrum Disorder

Italy
Federico II University

Completed

Dietetic Pattern in Children With Autism Spectrum Disorders

Autism Spectrum Disorder

Italy
CNS Onlus
University of Florence

Recruiting

rTMS Over the Supplementary Motor Area for Treatment-resistant Obsessive-compulsive Disorder. (rTMSOCD)

Obsessive-Compulsive Disorder

Italy
Santhera Pharmaceuticals
European Vision Institute Clinical Research Network

Completed

Leber Hereditary Optic Neuropathy (LHON) Historical Case Record Survey

Leber Hereditary Optic Neuropathy (LHON)

Belgium, France, Denmark, Italy, Slovenia
IRCCS Burlo Garofolo

Recruiting

Gut-oral Axis Microbiome in Autism Spectrum Disorders

Autism Spectrum Disorder | Microbiota

Italy
IRCCS Centro San Giovanni di Dio Fatebenefratelli

Completed

Biomarkers of Change in BPD After Metacognitive Interpersonal Therapy-standard Approach (CLIMAMITHE)

Borderline Personality Disorder

Italy
Istituto per la Ricerca e l'Innovazione Biomedica

Completed

Virtual Reality Experiences as Tools to Support Mental Health in Parents of Children With Autism (Mind-VR)

Autism Spectrum Disorder | Parents

Italy
Universita di Verona

Not yet recruiting

Digital Telerehabilitation in Functional Motor Disorders

Functional Movement Disorder

Italy
University of Campania "Luigi Vanvitelli"
University of Pisa; University of Bologna; University of Roma La Sapienza; Universita... and other collaborators

Recruiting

Psychoeducational Intervention for Families With a Member Affected by Major Depression

Depressive Disorder, Major

Italy
Institute of Neuroscience, Florence, Italy

Completed

Ondansetron Augmentation in Treatment-resistant OCD

Obsessive Compulsive Disorder

Italy
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Completed

Boosting Psychotherapy Effects by Means of Transcranial Direct Current Stimulation (PSYCHOBOOST)

Major Depressive Disorder

Italy
Istituto per la Ricerca e l'Innovazione Biomedica
Messina, Italy

Recruiting

Acquisition of Daily Living Skills in Autistic Children: Comparison Between QR Code and a Human Operator

Autism Spectrum Disorder | Autism

Italy
Istituto per la Ricerca e l'Innovazione Biomedica
Comune di Messina

Recruiting

Awareness Training in Children With Autism Spectrum Disorder.

Autism Spectrum Disorder | Autism

Italy
Istituto per la Ricerca e l'Innovazione Biomedica
Comune di Messina

Recruiting

Emotional Regulation in Individuals With Autism

Autism Spectrum Disorder | Autism

Italy
Istituto per la Ricerca e l'Innovazione Biomedica
Comune di Messina

Not yet recruiting

Static Balance in Children With Autism vs. Neurotypical Peers

Autism Spectrum Disorder | Autism

Italy
Istituto per la Ricerca e l'Innovazione Biomedica
Comune di Messina

Recruiting

A Kinematic Analysis of Motor Planning and Movement Execution of Children With Autism Spectrum Condition

Autism Spectrum Disorder | Autism

Italy
Istituto per la Ricerca e l'Innovazione Biomedica
Fondazione di Comunità Messina onlus

Recruiting

Immersive Room for Visual Attention in Children With Autism Spectrum Disorders

Autism Spectrum Disorder | Autism

Italy

Clinical Trials on Mitochondrial Disorders in Italy

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