Clinical Trials on Mitochondrial Genetic Disorders

Total 152427 results

AGO Study Group
Essex Pharma GmbH; MedServ. GmbH, Wiesbaden

Completed

Combination Chemotherapy Consisting of Pegylated Liposomal Doxorubicin and Carboplatin in Malignant Gynecologic Tumours

Cervical Cancers | Cancer of the Ovary Treated as 2nd Line Therapy | Muellerian Mixed Tumours | Tumours of the Uterus | Non-Epithelial Ovarian Tumours

Germany
University of Texas Southwestern Medical Center
Donald W. Reynolds Foundation

Completed

Dallas Heart Study 2: Return Clinic Visit for the Dallas Heart Study Cohort

Myocardial Infarction | Hypertension | Obesity | Diabetes Mellitus | Atherosclerosis | Congestive Heart Failure | Metabolic Syndrome X | Left Ventricular Hypertrophy

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Unknown

Biomarkers in Predicting Response in Patients With Advanced Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer Treated on GOG-0172 or GOG-0182

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cavity Cancer
National Center for Research Resources (NCRR)
University of California, Los Angeles

Completed

Study of the Effect of Four Methods of Cardiopulmonary Resuscitation Instruction on Psychosocial Response of Parents With Infants at Risk of Sudden Death

Pulmonary Hypertension | Respiratory Distress Syndrome | Bronchopulmonary Dysplasia
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Etoposide, Filgrastim, and Plerixafor in Improving Stem Cell Mobilization in Treating Patients With Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
University of Washington
National Cancer Institute (NCI)

Completed

Vorinostat, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Lymphoma or Previously Untreated T-Cell Non-Hodgkin Lymphoma or Mantle Cell Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Completed

Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Immunoblastic... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Low-Dose Total Body Irradiation and Donor Peripheral Blood Stem Cell Transplant Followed by Donor Lymphocyte Infusion in Treating Patients With Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, or Multiple Myeloma

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions

United States, Germany, Italy
National Cancer Institute (NCI)

Completed

Veliparib, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory Lymphoma, Multiple Myeloma, or Solid Tumors

Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Completed

Alisertib in Combination With Vorinostat in Treating Patients With Relapsed or Recurrent Hodgkin Lymphoma, B-Cell Non-Hodgkin Lymphoma, or Peripheral T-Cell Lymphoma

Recurrent Adult Burkitt Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Waldenstrom... and other conditions

United States
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy and Peripheral Stem Cell Transplant in Treating Patients With Non-Hodgkin's Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Lithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem Cell Transplant (GVHD)

Primary Myelofibrosis | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal... and other conditions

United States
Roswell Park Cancer Institute
Lumeda,Inc.

Active, not recruiting

Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery

Malignant Mesothelioma | Non-Small Cell Lung Carcinoma | Pleural Disorder

United States
University of Colorado, Denver
Children's Hospital Colorado

Completed

Randomized Trial of NSAID vs Placebo Prior to Ureteral Stent Removal

Urolithiasis | Disorder of Urinary Stent | Ureteral Spasm | Ureteropelvic Junction Obstruction

United States
Novo Nordisk A/S

Terminated

Cardiovascular Effects on Growth Hormone Therapy in Adults With Growth Hormone Deficiency

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Greece
Exoneural Network AB

Not yet recruiting

The Exopulse Mollii Suit Study - a Database for Routine Follow-up of Clinical Outcomes

Stroke | Multiple Sclerosis | Cerebral Palsy | Spinal Cord Injuries | Neurologic Disorder

Sweden
ReVivo Medical, Corp.
The Cleveland Clinic; Albany Medical College; IGEA

Recruiting

CEM-Plate and CEM-Cage First-In-Human Use Efficacy Study

Neck Pain | Spondylosis | Spondylosis With Myelopathy | Spondylosis With Radiculopathy | Spondylosis With Radiculopathy Cervical Region | Intervertebral Disc Disorder Cervical

United States
Institut Paoli-Calmettes

Recruiting

Pancreatic Radiofrequency Under High Echo-endoscopy in the Management of Pancreatic Neuroendocrine Tumors (RFANET)

Neuroendocrine Tumor Grade 1 | Neuroendocrine Tumor of Pancreas (Disorder)

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Genentech, Inc.

Recruiting

AZA + Venetoclax as Maintenance Therapy in Patients With AML in Remission

Acute Myeloid Leukemia | Therapy-Related Acute Myeloid Leukemia | Hematologic and Lymphocytic Disorder | Acute Myeloid Leukemia in Remission | FLT3 Gene Mutation | Minimal Residual Disease Persistence

United States
Oneness Biotech Co., Ltd.

Completed

A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled MBS-COV (SNS812) in Healthy Participants

Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2 (Disorder)

United States
Ankara City Hospital Bilkent

Completed

Genital Wart and Sexuality in Adolescence

Sexual Dysfunction | Genital Wart | Adolescent Development | Sexual Disorder, Physiological

Turkey
Novo Nordisk A/S

Completed

Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Mild and Moderate Degrees of Hepatic Impairment Compared to Subjects With Normal Hepatic Function.

Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency

Slovakia
Stanford University
National Cancer Institute (NCI)

Terminated

Ipilimumab and Local Radiation for Selected Solid Tumors

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Monoclonal Antibody Therapy Before Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoid Malignancies

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Lenalidomide With or Without Rituximab in Treating Patients With Progressive or Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Prolymphocytic Leukemia, or Non-Hodgkin Lymphoma Previously Treated With Donor Stem Cell Transplant

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions

United States
University of Udine

Recruiting

Tumor Microenvironment in Ovarian Cancer (MICO)

Ovarian Cancer Stage IV | Ovarian Cancer Stage III

Italy
Fengzhi Feng

Recruiting

Dalpiciclib Combined With Letrozole in HR+/HER2 - Gynecologic Solid Tumors

Recurrent Ovarian Carcinoma

China
UMC Utrecht
Johns Hopkins University

Recruiting

Investigation on the Cortical Communication System (CortiCom)

Neuromuscular Diseases | Traumatic Brain Injury | Locked-in Syndrome | Brainstem Stroke

Netherlands
MedSIR

Not yet recruiting

Niraparib Rechallenge After Surgery in Ovarian Cancer Patients With Oligometastatic Progression (ANALLISA)

Ovarian Cancer | Oligometastatic Disease | Serous Ovarian Tumor
Cardresearch

Recruiting

A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial (REVIVE)

Chronic Fatigue Syndrome | Long COVID-19 Syndrome

Brazil
Coordinación de Investigación en Salud, Mexico
Baxter Healthcare Corporation

Not yet recruiting

Continuous Glucose Monitoring in Patients With Diabetes on Peritoneal Dialysis

Peritoneal Dialysis | Diabetes Mellitus Type 2 | Kidney Disease, Chronic
Dr. Behcet Uz Children's Hospital

Recruiting

Decremental Esophageal Catheter Filling Volume Titration For Transpulmonary Pressure Measurement (DECFVTTPM)

Acute Respiratory Distress Syndrome | Acute Respiratory Failure | Pediatric Acute Respiratory Distress Syndrome (PARDS)

Turkey
University Health Network, Toronto

Not yet recruiting

Predicting Outcome of Cytoreduction in Advanced Ovarian Cancer, Using a Machine Learning Algorithm and Patterns of Disease Distribution at Laparoscopy (PREDAtOOR) (PREDAtOOR)

Ovarian Cancer Stage IV | Ovarian Cancer Stage III
Tianjin Nankai Hospital

Recruiting

Electroacupuncture Modulates SPMs Metabolism and Respiratory Symptoms in Patients With Sepsis Complicating ARDS

Sepsis | Acute Respiratory Distress Syndrome

China
IRCCS Azienda Ospedaliera Universitaria San Martino...
AstraZeneca

Recruiting

GLUcose Transport and REnalPROtection in Chronic Kidney Disease (GLUTREPRO)

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Disease

Italy
University Hospital, Tours

Recruiting

French National Cohort MATRIX "Renal and Systemic Thrombotic Microangiopathy" (MATRIX)

Kidney Diseases | Hemolytic Uremic Syndrome | Acute Kidney Injury | Thrombotic Microangiopathy | Nephrology

France
Second Affiliated Hospital of Guangzhou Medical...

Not yet recruiting

Aribulin Combined With Carboplatin and Bevacizumab in the Treatment of Ovarian Cancer

Ovarian Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

A Study of Creatine Combined With Curcumin in the Intervention of Early Cachexia in Upper Gastrointestinal Tumors

Stage IV Gastric Cancer | Stage IV Esophageal Cancer | Stage IIIA Gastric Cancer | Stage IIIB Gastric Cancer | Stage III Esophageal Cancer
Terra Biological LLC
Bateman Horne Center

Recruiting

REGAIN: RCT of Oxaloacetate for Fatigue in Long COVID

Fatigue Syndrome, Chronic | Post-COVID-19 Syndrome

United States
Sonnet BioTherapeutics
Hoffmann-La Roche

Recruiting

Combination of SON-1010 (IL12-FHAB) and Atezolizumab in Patients With Platinum-resistant Ovarian Cancer

Advanced Solid Tumor | Platinum-resistant Ovarian Cancer

United States, Australia
Henry Ford Health System

Recruiting

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

Glioma | Glioblastoma | Astrocytoma | Malignant Glioma of Brain | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | GBM | Malignant Astrocytoma

United States
The New Model of Care, Hail Health Cluster
Health Holding Company, Hail Health Cluster

Not yet recruiting

Application of Artificial Intelligence in Early Detection of Eye Complications in Diabetics (AI)

Artificial Intelegence | Diabetic Retinopathy Associated With Type 2 Diabetes Mellitus | Macular Edema Due to Type 2 Diabetes Mellitus
Medisch Spectrum Twente
Medical School Medisch Spectrum Twente; Techmed University of Twente; Erasmus...

Recruiting

Coeliac Artery Release or Sham Operation (CARoSO)

Mesenteric Ischemia | Median Arcuate Ligament Syndrome | Dunbar Syndrome | Coeliac Artery Compression | Celiac Artery Compression Syndrome

Netherlands
National Cancer Center, Korea

Recruiting

HIPEC for Platinum-Resistant Recurrent Ovarian Cancer (KOV-HIPEC-02)

Epithelial Ovarian Cancer

Korea, Republic of
GlaxoSmithKline

Recruiting

Efficacy and Safety of Depemokimab Compared With Mepolizumab in Adults With Relapsing or Refractory Eosinophilic Granulomatosis With Polyangiitis (EGPA) (OCEAN)

Eosinophilic Granulomatosis With Polyangiitis

Canada, France, Italy, Spain, Belgium, Korea, Republic of, United States, Japan, China, Czechia, Hungary, Israel, Portugal, Poland, Netherlands, United Kingdom, Austria, Argentina, Australia, Brazil, Germany, Sweden
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian Cancer

Platinum-Resistant Ovarian Carcinoma

United States
Hospital Galdakao-Usansolo
Instituto de Salud Carlos III; European Regional Development Fund

Recruiting

COVID-19, Patients' Evolution and the Influence of the Pandemic on Health Care and Outcomes in Chronic Diseases

Pulmonary Disease, Chronic Obstructive | Depressive Symptoms | COVID-19 Pandemic | Heart Failure, Congestive

Spain
Assistance Publique - Hôpitaux de Paris
URC-CIC Paris Descartes Necker Cochin; French Vasculitis Study Group

Recruiting

Study of Mepolizumab-based Regimen Compared to Conventional Therapeutic Strategy in Patients With Eosinophilic Granulomatosis With Polyangiitis (E-merge) (E-merge)

Eosinophilic Granulomatosis With Polyangiitis

France
Chinese University of Hong Kong

Recruiting

High Concentration Oxygen for Pneumocephalus After Evacuation of Chronic Subdural Haematoma (HOPE)

Recurrence | Chronic Subdural Hematoma | Oxycephaly

Hong Kong

Clinical Trials on Mitochondrial Genetic Disorders

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CROs in Germany

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Rare Diseases

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