Clinical Trials on Mitral Valve Insufficiency

Total 30205 results

University Hospital Inselspital, Berne

Completed

Effect of Etomidate on Hemodynamics and Adrenocortical Function After Cardiac Surgery

Coronary Artery Disease | Mitral Valve Regurgitation

Switzerland
Edwards Lifesciences
ICON plc

Terminated

Observational Registry on the HARPOON Device (REPLICATE)

Severe Degenerative Mitral Regurgitation Due to Mid-segment Posterior Leaflet Prolapse

Germany, Spain, Switzerland
University of Roma La Sapienza

Unknown

Clinical and Geriatric Assessment in Elderly Patients Before and After TAVI or MitraClip Positioning

Mitral Valve Insufficiency | Aortic Stenosis Senile

Italy
Southern Illinois University

Withdrawn

Medical Versus Surgical Management of Moderate Mitral Regurgitation Following Percutaneous Coronary Intervention

Myocardial Infarction | Mitral Regurgitation

United States
Fundación para la Investigación Biosanitaria del...
Meditrial Europe Ltd.

Not yet recruiting

Early Transcatheter Mitral Valve Repair After Myocardial Infarction (EMCAMI)

Acute Mitral Regurgitation

Spain, Italy, Netherlands, Israel
Medical University of Silesia
Ministry of Health, Poland

Unknown

Should we Repair Ischemic Mitral Regurgitation?

Coronary Disease | Mitral Valve Insufficiency

Poland
Deutsches Herzzentrum Muenchen

Unknown

Abrogation of Mitral Regurgitation Using the MitraClip System in High-Risk Patients Unsuitable for Surgery (ISAR-CLIP)

Mitral Regurgitation

Germany
Charite University, Berlin, Germany

Completed

Silent sTROke duriNG MitraClip Implantation (STRONG)

Mitral Regurgitation | Silent Stroke

Germany
Istanbul University - Cerrahpasa (IUC)

Enrolling by invitation

Biomechanical Taping on Low Back Pain With Increased Foot Pronation

Low Back Pain | Functional Mitral Regurgitation | Taping | Foot Posture

Turkey
Duke University
National Heart, Lung, and Blood Institute (NHLBI); Heart Failure Clinical Research...

Terminated

Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart Failure (SMMART-HF)

Heart Failure | Mitral Valve Insufficiency

United States, Canada
Imperial College London
University Hospitals, Leicester; Medical University of Silesia; Royal Brompton... and other collaborators

Completed

Randomised Ischaemic Mitral Evaluation (RIME) Trial (RIME)

Coronary Artery Disease | Mitral Regurgitation

United Kingdom, Poland
IRCCS San Raffaele

Unknown

Percutaneous Mitral Valve Repair in Cardiogenic Shock: Mitra-Shock Study (MSS)

Mitral Regurgitation Functional

Italy
Emory University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Improving Mitral Repair for Functional Mitral Regurgitation (IMPROVE-FMR)

Cardiovascular Diseases | Coronary Artery Disease | Heart Disease | Valvular Heart Disease | Congestive Heart Failure | Cardiomyopathy | Mitral Valve Disease

United States
East Carolina University
GlaxoSmithKline

Unknown

Pilot Study of Lovaza (Omega 3 Fatty Acids) to Improve Cardiac Antioxidant/Anti-inflammatory Profile Before Cardiac Surgery

Mitral Valve Regurgitation | Left Atrium Dilatation and Hypertrophy | Mitochondrial Dysfunction in the Heart | Cardiomyocyte Apoptosis | Cardiac Inflammation

United States
Kaohsiung Veterans General Hospital.
National Science Council, Taiwan

Completed

Left Atrial Distensibility to Predict Left Ventricular Filling Pressure and Prognosis in Patients With Severe Mitral Regurgitation

Heart Failure | Atrial Fibrillation | Mitral Valve Insufficiency

Taiwan
Imperial College London

Completed

The Right Ventricular Pulmonary Circulation Continuum in Mitral Valve Disease Study (RIPCOM1)

Mitral Regurgitation | Pulmonary Hypertension

United Kingdom
Chengdu Silara Meditech Inc.

Not yet recruiting

To Evaluate Safety and Effectiveness of Transcatheter Aortic Valve System in Patients With Severe Aortic Insufficiency

Aortic Insufficiency
Biostable Science & Engineering

Completed

The HAART 300 Annuloplasty Ring Trial Extended Safety and Performance

Aortic Insufficiency

Germany, Czech Republic
Foldax, Inc

Active, not recruiting

Early Feasibility Study for the Foldax TRIA Mitral Heart Valve Replacement (FOLDAX)

Mitral Valve Stenosis | Mitral Valve Disease | Mitral Valve Failure

United States
University Hospital, Geneva

Active, not recruiting

Impact of Mitral Regurgitation on Coronary Haemodynamics and Instantaneous Effect of Transcatheter Mitral Valve Repair (MitraFLOW)

Coronary Artery Disease | Mitral Regurgitation | Mitral Valve Insufficiency | Coronary Stenosis

Switzerland
JenaValve Technology, Inc.

Active, not recruiting

The JenaValve ALIGN-AR Pivotal Trial (ALIGN-AR)

Aortic Valve Disease | Aortic Regurgitation | Aortic Valve Insufficiency | Aortic Insufficiency

United States
RWTH Aachen University

Completed

Examination of Valve Insufficiency Before and After MitraClip or TAVI Procedure by 3D Echocardiography Compared to MRI (3D_TTE_TAVI)

Aortic Stenosis | Mitral Valve Insufficiency | Development of Standardized Assessment TAVI and MitraClip Procedures by Echocardiography

Germany
Edwards (Shanghai) Lifesciences Medical Supplies...

Completed

A Retrospective Study to Collect the Data From the Patients Who Had the Perimount Heart Valve Replacement Surgery in China During 2001 to 2007

Mitral Valve or Aortic Valve Replacement

China
Children's Healthcare of Atlanta

Terminated

Incidence of Neo-Aortic Insufficiency

Congenital Disorders

United States
Erasmus Medical Center

Recruiting

Coronary Physiology Peri-Transcatheter Left-sided Valvular Interventions (POTUS)

Coronary Artery Disease | Aortic Valve Stenosis | Mitral Regurgitation | Fractional Flow Reserve

Netherlands
Edwards Lifesciences

Active, not recruiting

Clinical Study to Evaluate the Performance of Magna Ease Heart Valve in Chinese Patients

Mitral Valve or Aortic Valve Replacement

China
Charite University, Berlin, Germany

Recruiting

Berlin Registry of Right Heart Interventions

Pulmonary Regurgitation | Tricuspid Regurgitation

Germany
Fundación Investigación Sanitaria en León
Abbott Medical Devices

Completed

MitraClip in Acute Mitral Regurgitation

Mitral Regurgitation | Acute Myocardial Infarction
Ottawa Heart Institute Research Corporation

Recruiting

Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock (MINOS)

Mitral Regurgitation | Cardiogenic Shock

United States, Canada
Edwards Lifesciences

Completed

Clinical Study to Evaluate the Performance of Perimount Heart Valve in Chinese Patients

Mitral Valve or Aortic Valve Replacement

China
Asan Medical Center
Merck Sharp & Dohme LLC

Completed

Ertugliflozin for Functional Mitral Regurgitation (EFFORT)

Mitral Valve Insufficiency | Left Ventricular Systolic Dysfunction

Korea, Republic of
Kuopio University Hospital
Turku University Hospital; UKK Institute

Recruiting

Personalized Activity Intervention in Rehabilitation After Cardiac Operations (the PACO Trial) (PACO)

Coronary Artery Disease | Aortic Valve Stenosis | Mitral Valve Insufficiency

Finland
Boston Children's Hospital
Northwell Health; Seattle Children's Hospital; University of California, San... and other collaborators

Active, not recruiting

Natural History of Melody Valve in the Mitral and Tricuspid Position

Diseases of Mitral Valve | Tricuspid Valve Disorder
Kaohsiung Veterans General Hospital.
E-DA Hospital

Recruiting

The Prognostic Impact of Using High-dose Hydralazine in Severe Systolic Heart Failure With Hemodynamically Significant Mitral Regurgitation

Mitral Regurgitation | Systolic Heart Failure Stage D (Disorder)

Taiwan
Ancora Heart, Inc.

Active, not recruiting

Early Feasibility Study of the AccuCinch® Ventricular Restoration System in Patients With Prior Mitral Valve Intervention (PMVI) and Recurrent Mitral Regurgitation (CorCinch-PMVI)

Heart Failure | Cardiomyopathy, Dilated

United States
Konkuk University Medical Center

Completed

Effect of Brief Nebulization of Milrinone on Pulmonary Arterial Pressure Before Cardiopulmonary Bypass on Mitral Valve Surgery Patients

Mitral Regurgitation | Pulmonary Hypertension

Korea, Republic of
Assiut University

Not yet recruiting

Effect of Significant Ischemic Mitral Regurgitation on the Outcome of ST Segment Elevation Myocardial Infarction Patients Treated With Primary Percutaneous Coronary Intervention

Ischemic Mitral Regurgitation
Sheng Liu

Recruiting

Effect of RT3D-TEE-guided Mitral Valve Repair on Outcomes in Patients With Degenerative Mitral Valve Disease (TEEMR)

Degenerative Mitral Valve Disease

China
CryoLife, Inc.

Completed

CryoValve SG Pulmonary Human Heart Valve Post Clearance Study (SGPV)

Aortic Valve Stenosis | Aortic Valve Insufficiency | Pulmonary Valve Insufficiency | Pulmonary Valve Stenosis

United States
Tomsk National Research Medical Center of the Russian...

Active, not recruiting

Clinical and Fundamental Aspects of Prosthetics and Translocation of Mitral Valve Chordae

Degenerative Mitral Valve Disease

Russian Federation
Icahn School of Medicine at Mount Sinai
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health...

Active, not recruiting

Long Term Follow Up for CTSN Mitral Valve Repair Studies

Coronary Artery Disease | Mitral Valve Insufficiency

United States, Canada
Beijing Anzhen Hospital
Beijing Municipal Science & Technology Commission

Unknown

Mitral Valve Repair Combined Coronary Artery Bypass Grafting(CABG) Verus CABG Alone on Functional Ischemic Mitral Regurgitation

Coronary Artery Disease | Mitral Valve Insufficiency

China
Ottawa Heart Institute Research Corporation

Recruiting

REvascularization and Valve Intervention for Ischemic Valve diseasE: REVIVE Trial (REVIVE)

Coronary Artery Disease | Mitral Valve Insufficiency

Canada
Icahn School of Medicine at Mount Sinai
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health... and other collaborators

Completed

Comparing the Effectiveness of a Mitral Valve Repair Procedure in Combination With Coronary Artery Bypass Grafting (CABG) Versus CABG Alone in People With Moderate Ischemic Mitral Regurgitation

Coronary Artery Disease | Mitral Valve Insufficiency

United States, Canada, Denmark
Edwards Lifesciences

Completed

Surgical Treatment of Aortic Stenosis With a Next Generation, Rapid Deployment Surgical Aortic Valve (TRANSFORM™)

Aortic Valve Stenosis | Aortic Valve Stenosis With Insufficiency | Regurgitation, Aortic Valve | Aortic Valve Incompetence

United States
Sorin Group USA, Inc.

Terminated

Perceval S Aortic Heart Valve Study- North America

Aortic Valve Stenosis | Aortic Valve Stenosis With Insufficiency | Regurgitation, Aortic Valve | Aortic Valve Incompetence

United States
October 6 University
Beni-Suef University; National Heart Institute, Egypt

Recruiting

Effect of Dapagliflozin on Secondary Mitral Regurgitation

Dilated Cardiomyopathy

Egypt
Scripps Translational Science Institute

Active, not recruiting

Genomic Investigation of Cardiovascular Diseases

Myocardial Infarction | Coronary Artery Disease | Atrial Fibrillation | Aortic Stenosis | Mitral Regurgitation | Idiopathic Cardiomyopathy

United States
The Cleveland Clinic
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Phenotypic Classification of FMR With CMR

Functional Mitral Regurgitation | Nonischemic Congestive Cardiomyopathy

United States
Biostable Science & Engineering

Completed

HAART 200 Aortic Valve Annuloplasty Trial

Aortic Insufficiency

Germany

Clinical Trials on Mitral Valve Insufficiency

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