Clinical Trials on Mixed Connective Tissue Disease

Total 58288 results

UMC Utrecht
M.D. Anderson Cancer Center; Odense University Hospital; Radboud University Medical... and other collaborators

Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study (MOMENTUM)

Neoplasms | Quality of Life | Breast Cancer | Head and Neck Cancer | Head and Neck Neoplasms | Gynecologic Cancer | Liver Neoplasms | Pancreatic Neoplasms | Pancreatic Cancer | Esophageal Cancer | Lung Cancer | Rectal Cancer | Rectal Neoplasms | Prostate Cancer | Brain Cancer | Brain Tumor | Bladder Cancer | Liver Metastases | T... and other conditions

United States, Netherlands, Germany, Canada, Denmark, United Kingdom, Australia, Belgium, Italy
National Cancer Institute (NCI)

Completed

Veliparib, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory Lymphoma, Multiple Myeloma, or Solid Tumors

Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma and other conditions

United States
University of Washington
National Cancer Institute (NCI)

Completed

Vorinostat, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Lymphoma or Previously Untreated T-Cell Non-Hodgkin Lymphoma or Mantle Cell Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
AbbVie

Terminated

Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors

Glioblastoma | Medullary Thyroid Cancer | Malignant Melanoma | Other Solid Tumors | Large-Cell Neuroendocrine Carcinoma | Neuroendocrine Prostate Cancer | High Grade Gastroenteropancreatic Neuroendocrine Carcinoma | Other Neuroendocrine Carcinoma

United States
Medical University of South Carolina
Patient-Centered Outcomes Research Institute

Enrolling by invitation

Improving Maternal Mental Health & SUD Screening and Treatment

Postpartum Depression | Substance Use Disorders | Mental Health Issue | Postpartum Anxiety

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Everolimus and Gefitinib in Treating Patients With Progressive Glioblastoma Multiforme or Progressive Metastatic Prostate Cancer

Prostate Cancer | Brain and Central Nervous System Tumors

United States, Spain
University of New Mexico
National Institute of Neurological Disorders and Stroke (NINDS); University...

Terminated

Permeability MRI in Cerebral Cavernous Malformations Type 1 in New Mexico: Effects of Statins

Cerebral Cavernous Malformations | Cavernous Angioma, Familial | Cerebral Cavernous Hemangioma

United States
Instituto do Cancer do Estado de São Paulo
University of Sao Paulo General Hospital

Terminated

Cryoablation of Bone Metastases From Endocrine Tumors

Neoplasm Metastasis | Neuroendocrine Tumors | Bone Metastases | Pheochromocytoma | Thyroid Neoplasm | Adrenal Neoplasm

Brazil
BioXcel Therapeutics Inc

Active, not recruiting

A Trial of BXCL701 and Pembrolizumab in Patients With mCRPC Either Small Cell Neuroendocrine Prostate Cancer or Adenocarcinoma Phenotype.

Prostate Cancer | Neuroendocrine Tumors | Small Cell Carcinoma

United States, United Kingdom
Centre Leon Berard

Completed

Study of SBRT Efficacy on Intra and Extra -Cranial Tumors or Metastasis in Pediatrics Population (SBRT Pediatrics) (SBRT)

Ependymoma | Brain Metastasis | Lung Tumors | Spinal Tumors

France
Debra Weese-Mayer
Children's Hospital of Philadelphia; Seattle Children's Hospital; Ann & Robert... and other collaborators

Recruiting

Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS)

Congenital Central Hypoventilation Syndrome | Congenital Central Hypoventilation | CCHS | CCHS With Hirschsprung Disease | CCHS With Neural Crest Tumor | CCHS With Neuroblastoma

United States
Shaheen Shagufta
National Cancer Institute (NCI)

Completed

Capecitabine, Temozolomide, and Bevacizumab for Metastatic or Unresectable Pancreatic Neuroendocrine Tumors

Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Gastrinoma | Glucagonoma | Insulinoma | Pancreatic Polypeptide Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations

Recurrent Ovarian Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Renal Cell Carcinoma | Stage III Renal Cell Cancer | Endometrial Carcinoma | Stage III Bladder Cancer | Cervical Squamous Cell Carcinoma | Stage IV Breast Cancer | Malignant Uterine Neoplasm | Recurrent Bladder Carcinoma | Recurrent... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage IV Breast Cancer | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Multiscale Omics for the Development of a Cohort Database and Study Platform in Breast Cancer Survivors

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Ipilimumab, Nivolumab, and Talimogene Laherparepvec Before Surgery in Treating Participants With Localized, Triple-Negative or Estrogen Receptor Positive, HER2 Negative Breast Cancer-deleted

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
Fred Hutchinson Cancer Center
Breast Cancer Research Foundation

Completed

Lifestyle Program (Scalable Nutrition and Physical Activity) for the Improvement of Nutrition and Physical Activity in Stage 0-III Breast Cancer Survivors

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With Cancer (IMPROVE)

Melanoma | Head and Neck Cancer | Gynecologic Cancer | Thoracic Cancer | Head and Neck Tumor | Gynecologic Tumor | Thoracic Tumor

United States
Five Prime Therapeutics, Inc.
Bristol-Myers Squibb

Completed

Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers (FPA008-003)

Renal Cell Carcinoma | Head and Neck Cancer | Pancreatic Cancer | Ovarian Cancer | Malignant Glioma | Advanced Solid Tumors | Non-small Cell Lung Cancer

United States
National Taiwan University
National Taiwan University Hospital

Recruiting

Stress and Coping, Resilience, and Compassion Fatigue of Front-line Nurses During COVID-19 Pandemic

COVID-19 Pandemic | Mental Health Issue | Stressor, Psychological

Taiwan
Syndax Pharmaceuticals
Merck Sharp & Dohme LLC

Completed

Ph1b/2 Dose-Escalation Study of Entinostat With Pembrolizumab in NSCLC With Expansion Cohorts in NSCLC, Melanoma, and Colorectal Cancer

Melanoma | Non-Small Cell Lung Cancer | Mismatch Repair-Proficient Colorectal Cancer

United States
Eric W. Sargent, MD
Med-El Corporation

Withdrawn

Maintaining Cochlear Patency After VIIIth Nerve Surgery

Acoustic Neuroma | Labyrinthitis Ossificans | Profound Hearing Impairment

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Withdrawn

Web-Based Coping and Communication Skills Intervention in Improving Psychological Adaptation in Patients With Gynecological Cancer

Stage II Uterine Corpus Cancer AJCC v7 | Uterine Carcinosarcoma | Endometrial Carcinoma | Stage II Cervical Cancer AJCC v7 | Stage IIA Cervical Cancer AJCC v7 | Stage IIB Cervical Cancer AJCC v6 and v7 | Stage IIIB Cervical Cancer AJCC v6 and v7 | Stage IVA Cervical Cancer AJCC v6 and v7 | Stage 0 Fallopian... and other conditions

United States
Nationwide Children's Hospital
Novartis

Not yet recruiting

Study of Ribociclib and Everolimus in HGG and DIPG

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | WHO Grade IV Glioma

United States, Australia, United Kingdom, Canada, Germany, Netherlands
Nationwide Children's Hospital

Not yet recruiting

Targeted Pediatric High-Grade Glioma Therapy

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | WHO Grade IV Glioma

United States, Australia, United Kingdom, Canada, Germany, Netherlands
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors

Glioblastoma | Malignant Glioma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Astrocytoma, Grade III | Brain Stem Neoplasms, Malignant | Oligodendroblastoma

United States
Guangdong Zhongsheng Pharmaceutical Co., Ltd.

Unknown

A Phase 1 Study of ZSP1602 in Participants With Advanced Solid Tumors

Small Cell Lung Cancer | Glioblastoma | Medulloblastoma | Neuroendocrine Neoplasm | Basal Cell Carcinoma | Adenocarcinoma of Esophagogastric Junction

China
Novartis Pharmaceuticals

Terminated

Ceritinib Rare Indications Study in ALK+ Tumors

Glioblastoma | Anaplastic Large Cell Lymphoma | Inflammatory Myofibroblastic Tumor | Tumors With Aberrations in ALK

France, Czechia, Italy, Spain, Korea, Republic of, Thailand, Israel, Denmark
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Improving Patient-Centered Communication in Breast Cancer Through Patient and Provider Interventions (SHARES)

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Nipple Aspirate Fluid in Detecting Breast Cancer

Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC... and other conditions

United States
Bambino Gesù Hospital and Research Institute

Recruiting

GD2-CAR T Cells for Pediatric Brain Tumours

High Grade Glioma | Medulloblastoma, Childhood | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma | Embryonal Tumor | Brain Tumor Adult | Brain Tumor, Pediatric

Italy
OncoHost Ltd.

Recruiting

Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments (PROPHETIC)

Stage IV Non-small Cell Lung Cancer | Stage III Malignant Melanoma | Stage IV Small Cell Lung Cancer | Stage IV Malignant Melanoma

United States, Israel, United Kingdom, Germany, Spain
University of Göttingen
Hannover Medical School; Deutsche Kinderkrebsstiftung

Recruiting

International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013) (HIT-HGG-2013)

Diffuse Intrinsic Pontine Glioma | Gliomatosis Cerebri | Glioblastoma WHO Grade IV | Diffuse Midline Glioma Histone 3 K27M WHO Grade IV | Anaplastic Astrocytoma WHO Grade III

Germany
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
University of Pittsburgh
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Consensus-based Algorithms to Address Opioid Misuse Behaviors Among Individuals Prescribed LTOT

Chronic Pain | Opioid Misuse

United States
University Hospital, Clermont-Ferrand
University Hospital, Toulouse

Completed

French Version of POMI Scale (POMI)

Chronic Pain | Opioid Misuse
University of Pittsburgh
Staunton Farm Foundation

Completed

Integrative Psychosocial Group Treatment

Chronic Pain | Opioid Misuse

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

European Multicenter Study on Surgical Management of Advanced Thyroid Cancer (ATCEU)

Thyroid Neoplasms | Thyroid Cancer, Papillary | Thyroid Cancer, Follicular | Thyroid Carcinoma | Thyroid Cancer | Anaplastic Thyroid Cancer | Thyroid Medullary Carcinoma

Italy
Yusuf Menda
National Cancer Institute (NCI); National Institutes of Health (NIH); Holden...

Not yet recruiting

A Safety Study of 212Pb-Pentixather Radioligand Therapy

Carcinoid Tumor Lung | Neuroendocrine Tumor of the Lung | Carcinoma, Small-Cell Lung

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Roswell Park Cancer Institute; American Lebanese...

Recruiting

A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Glioblastoma Multiforme | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | High-grade Astrocytoma NOS

United States, Canada
Massive Bio, Inc.

Recruiting

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

Melanoma | Follicular Lymphoma | Carcinoma | Myelodysplastic Syndromes | Leukemia | Cancer | Breast Cancer | Myeloproliferative Disorders | Glioblastoma | Myelofibrosis | Ovarian Cancer | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Neuroendocrine Tumors | Non Small Cell Lung Cancer | COVID | Non Hodgkin Lymphoma | Cholang... and other conditions

United States
University of Utah

Active, not recruiting

Treating Opioid Misuse Via Mindfulness-Based Just-in-Time Adaptive Intervention (MORE-JITAI)

Chronic Pain

United States
University Hospital, Clermont-Ferrand
CEIP-A Lyon; CEIP-A Marseille; CEIP-A Caen; CEIP-A Lille; CEIP-A Montpellier; CEIP-A... and other collaborators

Completed

Prescription Opioid Misuse Assessment (POMA4)

Chronic Pain

France
Jose Seijas Amigo

Completed

SEMAGLUTIDE VERSUS GLP-1 RECEPTOR AGONISTS. EFFECTIVENESS , SAFETY AND QUALITY OF LIFE IN PATIENTS WITH DIABETES MELLITUS 2. OBSERVATIONAL, PROSPECTIVE AND MULTICENTER STUDY. SEVERAL STUDY. (SEVERAL)

Quality of Life | Diabetes Mellitus, Type 2 | Weight Loss | Safety Issues

Spain
University Hospital, Geneva

Recruiting

Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular Schwannoma

Ototoxicity | Vestibular Schwannoma

Switzerland
Sklifosovsky Institute of Emergency Care

Recruiting

Sonography-guided Resection of Brain Mass Lesions (SOMALI)

Arteriovenous Malformations | Tumor, Brain | Cavernoma | Intracerebral Hematoma

Russian Federation
Loxo Oncology, Inc.
Eli Lilly and Company

Active, not recruiting

A Study of Selpercatinib (LY3527723) in Participants With Advanced Solid Tumors Including RET Fusion-positive Solid Tumors, Medullary Thyroid Cancer and Other Tumors With RET Activation (LIBRETTO-321)

Solid Tumor | Medullary Thyroid Cancer

China
Sumitomo Pharma America, Inc.

Completed

First-in-human Study of Oral TP-0903 (a Novel Inhibitor of AXL Kinase) in Patients With Advanced Solid Tumors

Advanced Solid Tumors | Recurrent Ovarian Carcinoma | Colorectal Carcinoma | EGFR Positive Non-small Cell Lung Cancer | BRAF-Mutated Melanoma

United States
Oticon Medical

Completed

Auditory Nerve Monitoring Using Intra-cochlear Stimulation in Subjects With Acoustic Neuroma (NeuriStim)

Hearing Loss, Cochlear | Neurinoma of the Acoustic Nerve

France

Clinical Trials on Mixed Connective Tissue Disease

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Suriname

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

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