Clinical Trials on Mixed Connective Tissue Disease

Total 58681 results

Andrew J. Armstrong, MD
Bristol-Myers Squibb

Recruiting

A Study of Chemoimmunotherapy for the Treatment of Men With Neuroendocrine or Aggressive Variant Metastatic Prostate Cancer (CHAMP)

Metastatic Prostate Cancer | Metastatic Prostate Neuroendocrine Carcinoma

United States
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Isolated Hepatic Perfusion With Melphalan in Treating Patients With Primary Unresectable Liver Cancer or Liver Metastases

Colorectal Cancer | Metastatic Cancer | Liver Cancer | Neuroendocrine Carcinoma | Islet Cell Tumor

United States
Eve Rodler

Not yet recruiting

Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy

Breast Cancer | Ovarian Cancer | Breast Neoplasm | Breast Carcinoma | Breast Cancer Stage IV | Breast Cancer Stage I | Breast Cancer Stage II | Invasive Breast Cancer | Cancer, Breast | Breast Cancer Stage III | Ovary Cancer | Malignant Tumor of Breast | Ovarian Cancer Stage IIIC | Ovarian Cancer Stage IV | Ovarian Cancer... and other conditions

United States
University of Vermont
American Society of Colon and Rectal Surgeons

Completed

Pre-Emptive Analgesia in Ano-Rectal Surgery (PEAARS)

Rectal Fistula | Hemorrhoids | Fissure in Ano | Anal Condyloma

United States
Columbia University

Withdrawn

Multi-Drug Analgesia vs. Standard Solution for Anal Surgery

Hemorrhoids | Fissure in Ano | Fistula;Rectal
Xi'an Xintong Pharmaceutical Research Co.,Ltd.
The First Hospital of Jilin University

Recruiting

Treatment of MB07133 Plus Sintilimab in Patients With Hepatocellular Carcinoma (MB07133)

Efficacy | Safety Issues | MTD

China
SOTIO Biotech AG
SOTIO Biotech a.s.

Active, not recruiting

Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumors

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Mesothelioma | Bladder Cancer | Triple Negative Breast Cancer | Small-cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Thyroid | Anal Cancer | Merkel Cell Carcinoma | Biliary... and other conditions

United States, France, Spain, Czechia
University of Chicago
Mayo Clinic; National Institute of Neurological Disorders and Stroke (NINDS); University of California, San Francisco and other collaborators

Recruiting

Biomarkers of CASH

Cerebral Cavernous Malformation | Cavernous Angioma | Hemorrhagic Microangiopathy

United States
St. Joseph's Hospital and Medical Center, Phoenix

Terminated

Effect of Oral Propranolol on mRNA Expresssion in Symptomatic Cavernous Malformation

Cerebral Cavernous Malformations

United States
Centre hospitalier de l'Université de Montréal...

Active, not recruiting

Transvenous Approach for the Treatment of Cerebral Arteriovenous Malformations (TATAM)

Unruptured Brain Arteriovenous Malformation | Ruptured Brain Arteriovenous Malformation | Arteriovenous Malformations, Cerebral

Canada, France
Centre Oscar Lambret
Institut de Biologie de Lille

Terminated

Early Biomarkers of Tumor Response in High Dose Hypofractionated Radiotherapy Word Package 3 : Immune Response

Melanoma | Kidney Neoplasms | Carcinoma, Hepatocellular | Colorectal Neoplasms

France
University of Calgary
University of Alberta

Completed

ENCOMPASS: Expansion Study A, RCT (ENCOMPASS)

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
Kaiser Permanente
Sanofi Pasteur, a Sanofi Company

Completed

Flublok v. Standard Dose Vaccine Effectiveness Among Kaiser Permanente Northern California Adults 18-64 Years

Stroke | Pneumonia | Influenza | Congestive Heart Failure | Acute Myocardial Infarction | Lower Respiratory Tract Infection

United States
Mayo Clinic

Recruiting

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Malignant Solid Neoplasm | Renal Cell Carcinoma | Hepatocellular Carcinoma | Metastatic Cutaneous Melanoma | Unresectable Cutaneous Melanoma | Lung Non-Small Cell Carcinoma | Urothelial Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Recurrent Head and Neck Squamous... and other conditions

United States
Washington University School of Medicine

Active, not recruiting

Role of Proton Pump Inhibitors on the Postoperative Course Following Pancreaticoduodenectomy

Pancreatic Cancer | Pancreatitis | Pancreas Cancer | Duodenal Cancer | Ampullary Cancer | Pancreas Neuroendocrine Tumor | Distal Extrahepatic Cholangiocarcinoma

United States
Imperial College London

Unknown

Cardiopulmonary Exercise Testing to Evaluate Pulmonary AVMs With and Without Airflow Obstruction (ExercisePAVM2)

Asthma | COPD | Hereditary Hemorrhagic Telangiectasia | Pulmonary Arteriovenous Malformations
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Comparing Capecitabine and Temozolomide in Combination to Lutetium Lu 177 Dotatate in Patients With Advanced Pancreatic Neuroendocrine Tumors

Metastatic Pancreatic Neuroendocrine Tumor | Unresectable Pancreatic Neuroendocrine Carcinoma

United States
Seoul National University Hospital

Enrolling by invitation

A Prospective Cohort Study for Patients With Adrenal Diseases

Cushing Syndrome | Pheochromocytoma | Primary Hyperaldosteronism | Adrenocortical Carcinoma | Adrenal Incidentaloma | Adrenal Adenoma

Korea, Republic of
Duke University
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors

Brain and Central Nervous System Tumors | Metastatic Cancer | Neuroblastoma

United States
A Thousand Colibris, S.L
Hospital Universitari Vall d'Hebron Research Institute; University Rovira i... and other collaborators

Not yet recruiting

MamaConecta: Digital Tool for Maternal Mental Health (DDT)

Postpartum Depression | Pregnancy Related | Mental Health Issue | Postpartum Anxiety | Well-Being, Psychological

Spain
National Cancer Institute (NCI)

Completed

MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia

Unspecified Childhood Solid Tumor, Protocol Specific | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone... and other conditions

United States, Canada
Brown University

Recruiting

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

Arthritis | Chronic Pain | Chronic Low-back Pain | Irritable Bowel Syndrome | Fibromyalgia | Acute Pain | Trauma, Multiple | Neuropathic Pain | Temporomandibular Joint Disorders | Post Operative Pain | Chronic Pain Syndrome | Chronic Shoulder Pain | Painful Diabetic Neuropathy | Chronic Migraine | Painful Bladder Syndrome and other conditions

United States
British Columbia Cancer Agency

Recruiting

DOTATOC PET/CT for Imaging NET Patients

Pituitary Adenoma | Neuroendocrine Tumors | Medulloblastoma | Small-cell Lung Cancer | Neuroblastoma | Meningioma | Merkel Cell Carcinoma | Pheochromocytoma | Paraganglioma | Gastrinoma | Glucagonoma | Insulinoma | Vipoma | Carcinoid | Ganglioneuroma | Medullary Carcinoma

Canada
Roswell Park Cancer Institute
National Cancer Institute (NCI); National Comprehensive Cancer Network

Terminated

Axitinib in Treating Patients With Melanoma That is Metastatic or Cannot Be Removed by Surgery

Recurrent Melanoma | Stage IV Melanoma | Metastatic Intraocular Melanoma | Recurrent Intraocular Melanoma | Stage IV Intraocular Melanoma | Stage IIIA Melanoma | Stage IIIB Melanoma | Stage IIIC Melanoma | Extraocular Extension Melanoma | Stage IIIA Intraocular Melanoma | Stage IIIB Intraocular Melanoma | Stage...

United States
National Cancer Institute (NCI)

Completed

Azacitidine and Recombinant Interferon Alfa-2b in Treating Patients With Stage III or Stage IV Melanoma or Stage IV Kidney Cancer That Cannot Be Removed By Surgery

Recurrent Melanoma | Stage IV Melanoma | Stage IV Renal Cell Cancer | Recurrent Renal Cell Cancer | Stage III Melanoma

United States
University of Calgary
University of Alberta

Completed

ENCOMPASS: Expansion Study C

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
University of Calgary
Alberta Innovates Health Solutions; Canadian Diabetes Association

Completed

Enhancing Community Health Through Patient Navigation, Advocacy and Social Support (ENCOMPASS)

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
Abbott Medical Devices

Completed

Hemodynamic-GUIDEd Management of Heart Failure (GUIDE-HF)

Heart Failure | Heart Failure, Diastolic | Heart Failure, Systolic | Heart Failure NYHA Class II | Heart Failure NYHA Class III | Heart Failure With Reduced Ejection Fraction | Heart Failure NYHA Class IV | Heart Failure With Normal Ejection Fraction | Heart Failure; With Decompensation | Heart Failure...

United States, Canada
PT Bio Farma

Completed

Safety and Immunogenicity of Vi-DT Typhoid Conjugate Vaccine (Bio Farma) in Adults and Children (Phase I)

Safety Issues

Indonesia
RWTH Aachen University

Recruiting

Diaphragm Atrophy and Dysfunction in Mechanical Ventilation (DAM)

Respiratory Failure | Mechanical Ventilation Complication | Diaphragm Issues | Intensive Care (ICU) Myopathy

Germany
University of Calgary

Completed

ENCOMPASS: Expansion Study B, RCT (ENCOMPASS)

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
Cairo University

Completed

Effect of Lung Volume Recruitment Technique After Extubation

Cough | Mechanical Ventilation Complication | Intensive Care Unit Acquired Weakness | Ineffective Airway Clearance | Diaphragm Issues

Egypt
University of California, San Francisco
University of Chicago; National Institute of Neurological Disorders and Stroke... and other collaborators

Recruiting

Modifiers of Disease Severity in Cerebral Cavernous Malformations

Cerebral Cavernous Malformations | Cavernous Angioma, Familial | Cerebral Cavernous Hemangioma

United States
National Cancer Institute (NCI)

Recruiting

National Cancer Institute "Cancer Moonshot Biobank"

Malignant Solid Neoplasm | Acute Myeloid Leukemia | Multiple Myeloma | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer... and other conditions

United States, Puerto Rico
Fudan University

Recruiting

Neuroendocrine Transformation in RB1/TP53 Inactivated NSCLC

Non-small Cell Lung Cancer | Neuroendocrine Carcinoma | Histology Transformation

China
Shanghai Jiao Tong University School of Medicine

Recruiting

Treatment of Advanced Endocrine Tumor With Iindividualized mRNA Neoantigen Vaccine (mRNA-0523-L001)

Medullary Thyroid Cancer | Pancreatic Neuroendocrine Tumor | Adrenal Cortical Carcinoma | Thymic Neuroendocrine Carcinoma

China
Darell D. Bigner, MD, PhD
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy After Radiation Therapy in Treating Patients With Primary Brain Tumors

Brain and Central Nervous System Tumors | Neuroblastoma

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

Follicular Lymphoma | Splenic Marginal Zone Lymphoma | Mantle Cell Lymphoma | Indolent Non-hodgkin Lymphoma | Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue | Nodal Marginal Zone Lymphoma

United States
Naestved Hospital

Recruiting

Safety of Ibuprofen After Major Orthopaedic Surgeries (PERISAFE)

Postoperative Complications | Postoperative Pain | Analgesia | Pain, Acute | Safety Issues | Knee Arthropathy | Hip Arthropathy | Analgesic Adverse Reaction

Denmark
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Crizotinib and Combination Chemotherapy in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma

Recurrent Neuroblastoma | Childhood Solid Neoplasm | Recurrent Childhood Anaplastic Large Cell Lymphoma

United States, Canada
National Cancer Institute (NCI)

Completed

Temsirolimus and Bryostatin 1 in Treating Patients With Unresectable or Metastatic Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Melanoma | Stage IV Melanoma | Stage IV Renal Cell Cancer | Recurrent Renal Cell Cancer

United States
Y-mAbs Therapeutics

Terminated

131I-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous System/Leptomeningeal Metastases

Neuroblastoma | Leptomeningeal Metastases | CNS Metastases

United States, Denmark, Japan, Spain
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

3T MRI Biomarkers of Glioma Treatment Response

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Beth Israel Deaconess Medical Center
National Cancer Institute (NCI)

Completed

Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain

Brain and Central Nervous System Tumors | Metastatic Cancer | Melanoma (Skin)

United States
AbbVie
Roche-Genentech

Completed

A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies

Non-Hodgkin's Lymphoma | Neuroblastoma | Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Malignancies

United States, Australia, Canada, France, Germany, Netherlands, Switzerland, United Kingdom
Fred Hutchinson Cancer Center

Completed

Donor Bone Marrow Transplant in Treating Young Patients With Cancer or a Non-Cancerous Disease

Sarcoma | Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Neuroblastoma

United States
National Cancer Institute (NCI)

Completed

Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Ovarian Carcinoma | Pancreatic Neuroendocrine Tumor | Unresectable Solid Neoplasm | Fibrolamellar Carcinoma

United States
Pharmassist Ltd
University of Athens

Active, not recruiting

Validation of Molecular Diagnostic Assays to Detect Cancer Biomarkers in Blood and Primary Tumor in HNSCC/NSCLC/Melanoma

Melanoma | Non Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma

Greece
Herbert Irving Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Thiotepa Followed by Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Malignant Glioma

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)
Exelisis

Completed

Cabozantinib-S-Malate Compared With Temozolomide or Dacarbazine in Treating Patients With Metastatic Melanoma of the Eye That Cannot Be Removed by Surgery

Stage IV Uveal Melanoma AJCC v7 | Recurrent Uveal Melanoma | Stage III Uveal Melanoma AJCC v7 | Stage IIIA Uveal Melanoma AJCC v7 | Stage IIIB Uveal Melanoma AJCC v7 | Stage IIIC Uveal Melanoma AJCC v7

United States, Canada

Clinical Trials on Mixed Connective Tissue Disease

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Ethiopia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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