Clinical Trials on Monogenic Diabetes

Total 20314 results

Outlook Therapeutics, Inc.

Active, not recruiting

A 3-month Study to Compare the Safety of ONS-5010 in Vials Versus Pre-filled Syringe in Subjects With Visual Impairment Due to Retinal Disorders (NORSE SEVEN)

Age-Related Macular Degeneration | Diabetic Macular Edema | Wet Macular Degeneration | Neovascular Age-related Macular Degeneration | BRVO - Branch Retinal Vein Occlusion

United States
Outlook Therapeutics, Inc.

Completed

A 3-month Study to Assess the Safety of ONS-5010 in Subjects With Visual Impairment Due to Retinal Disorders

Age-related Macular Degeneration | Diabetic Macular Edema | Wet Macular Degeneration | Neovascular Age-related Macular Degeneration | BRVO - Branch Retinal Vein Occlusion

United States
Mayo Clinic

Completed

Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity

Multiple Sclerosis | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Uveitis | Vasculitis | Psoriasis | Graves Disease | Systemic Sclerosis | Celiac Disease | Crohn Disease | Type 1 Diabetes Mellitus | Myasthenia Gravis | Ulcerative Colitis | Dermatomyositis | Polymyositis | Vitiligo | Hepatitis, Autoimmune | Polymyalgia... and other conditions

United States
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
Sanko University

Completed

Effectiveness of Family Collaborative Physiotherapy Programs With High-risk Infants

Cerebral Palsy | Infant, Premature, Diseases | Infant, Newborn, Disease | Infant Development | Infant, Very Low Birth Weight | Infant, Small for Gestational Age | Infant Asphyxia | Infant of Diabetic Mother

Turkey
Centre Hospitalier Universitaire de Saint Etienne
Ministry of Health, France

Completed

Influence of a Multi-parametric Optimization Strategy for General Anesthesia on Postoperative Morbidity and Mortality (OPTI-AGED)

Heart Failure | Stroke | Alcoholism | Diabetes | Cancer | Renal Insufficiency | Pulmonary Disease, Chronic Obstructive | Peripheral Vascular Diseases | Respiratory Insufficiency | Arrhythmias, Cardiac | Dementia | Coronary; Ischemic

France
Institut National de la Santé Et de la Recherche...
Gustave Roussy, Cancer Campus, Grand Paris; Ligue contre le cancer, France; Université...

Active, not recruiting

The French E3N Prospective Cohort Study (E3N)

Depression | Cardiovascular Diseases | Melanoma | Hypertension | Diabetes | Breast Cancer | Parkinson Disease | Inflammatory Bowel Diseases | Asthma | Endometriosis | Crohn Disease | Endometrial Cancer | Colo-rectal Cancer | Thyroid Cancer
Faculty Hospital Kralovske Vinohrady

Completed

The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic

Infections | Multiple Sclerosis | Autoimmune Diseases | Diabetes Mellitus, Type 1 | Rheumatoid Arthritis | Vaccine Reaction | Inflammatory Bowel Diseases | Psoriasis | Crohn Disease | Ulcerative Colitis | Down Syndrome | Atopic Dermatitis | Vitiligo | Alopecia Areata | COVID-19 Pandemic | Ankylosing Spondylitis | Lupus Erythematosus and other conditions

Czechia
Herlev and Gentofte Hospital
Copenhagen University Hospital, Denmark

Active, not recruiting

Cardiac Structure and Function in Patients With Cystic Fibrosis

Myocardial Infarction | Heart Diseases | Heart Failure | Stroke | Cystic Fibrosis | Heart Failure, Diastolic | Heart Failure, Systolic | Left Ventricular Dysfunction | Cystic Fibrosis-related Diabetes | Cystic Fibrosis Gastrointestinal Disease | Cystic Fibrosis of Pancreas | Cystic Fibrosis, Pulmonary | Cystic...

Denmark
Bijan Najafi, PhD
Orthotic Holdings, Inc.

Completed

OHI--Randomized Control Trial to Evaluate Efficacy, Acceptability, and Perception of Benefit of an Innovative Custom AFO

Diabetes | Cancer | Arthritis | Parkinson's Disease | Peripheral Arterial Disease | End Stage Renal Failure on Dialysis | Accidental Falls | Fall Due to Loss of Equilibrium | High Risk of Falls Due to Mobility Limitation

United States
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Collateral Damage From the COVID-19 Pandemic Observed in Patients Treated With Intravitreal Injections (IVT) of Anti-angiogenic Agents (COVIDIV)

Diabetic Macular Edema | Retinal Vein Occlusion | Age Related Macular Degeneration

France
Chelsea Therapeutics

Completed

Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) (NOH303)

Multiple System Atrophy | Neurogenic Orthostatic Hypotension | Dopamine Beta Hydroxylase Deficiency | Non-Diabetic Autonomic Neuropathy

United States, Australia, Canada, New Zealand
University of Florida
US Department of Veterans Affairs

Recruiting

Peripheral Nerve Blocks for Above-the-knee Amputations

Coronary Artery Disease | Hypertension | Pulmonary Disease, Chronic Obstructive | Peripheral Vascular Diseases | Hyperglycaemia (Diabetic)

United States
University of Leicester

Recruiting

The Multi-Ethnic Lifestyle Study (MELS)

Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse) | Cardiovascular Diseases | Stroke | Healthy | Diabetes Mellitus | Cancer | Chronic Kidney Diseases | Chronic Pain | Obstructive Sleep Apnea | Respiratory Disease

United Kingdom
University of Vermont
University of Massachusetts, Worcester; Arizona State University; Case Western... and other collaborators

Active, not recruiting

Integrating Behavioral Health and Primary Care for Comorbid Behavioral and Medical Problems (IBHPC)

Depression | Heart Failure | Hypertension | Diabetes | Arthritis | Chronic Pain | Irritable Bowel Syndrome | Insomnia | Asthma | Fibromyalgia | Anxiety | Substance Use Disorder | Chronic Obstructive Lung Disease | Problem Drinking

United States
GlaxoSmithKline

Completed

Gabapentin and Risk of Pancreatic Cancer and Renal Cancer (GPRD)

Epilepsy | Renal Cell Carcinoma | Hypertension | Diabetes | Restless Legs Syndrome | Pancreatic Cancer | Neuropathic Pain | Chronic Pancreatitis | Renal Cancer | Renal Pelvis Cancer
Institut National de la Santé Et de la Recherche...

Recruiting

IDMet (RaDiCo Cohort) (RaDiCo-IDMet) (IDMet)

Prader-Willi Syndrome | Angelman Syndrome | Beckwith-Wiedemann Syndrome | Pseudohypoparathyroidism | Silver Russell Syndrome | Transient Neonatal Diabetes Mellitus | Temple Syndrome | Kagami-Ogata Syndrome | Familial Precocious Puberty

France
University of Valencia
Hospital Universitario La Fe; Hospital General Universitario de Valencia; Hospital...

Completed

Intervention in Chronic Pediatric Patients and Their Families. (FACTORADAPT)

Asthma | Type 1 Diabetes | Allergic Rhinitis | Cystic Fibrosis | Pulmonary Disease | Atopic Dermatitis | Food Allergy | Allergic Asthma | Rhinoconjunctivitis | Primary Ciliary Dyskinesia | Short Stature

Spain
Wake Forest University Health Sciences
National Institute of Mental Health (NIMH); University of Alabama at Birmingham

Completed

Risk Assessment of Long-Haul Truck Drivers

HIV Infections | Hypertension | Obesity | Diabetes Mellitus | Hepatitis B | Hepatitis C | Gonorrhea | Chlamydia Infections | Hyperlipidemia

United States
Olawuyi Racett Nigeria Ltd

Completed

Medlink for Diagnosing of Diabetes Mellitus, COPD, CHF, Myasthenia Gravis and Hypertension (Medlink)

Hypertension | Diabetes Mellitus | Chronic Obstructive Pulmonary Disease | Myasthenia Gravis | Congestive Heart Failure

United Kingdom
Treatment Research Institute
Patient-Centered Outcomes Research Institute

Completed

Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions

Pneumonia | Diabetes Mellitus | Chronic Obstructive Pulmonary Disease | Alcohol Use | End-Stage Renal Disease | Congestive Heart Failure | Drug Use | Acute Myocardial Infarction

United States
Marlous Hall

Completed

Association of Long-term Conditions With Survival Following Heart Attack in England and Wales

Diabetes Mellitus | Chronic Obstructive Pulmonary Disease | Peripheral Vascular Disease | Chronic Heart Failure | Acute Myocardial Infarction | Chronic Renal Failure | Cerebrovascular Disease
Dongzhimen Hospital, Beijing
Wuhan Third Hospital; The Second Affiliated Hospital of Tianjin University... and other collaborators

Unknown

BuqitongluO Granule for Qi Deficiency and Blood Stasis Syndrome (BOSS)

Coronary Artery Disease | Diabetic Peripheral Neuropathy | Stroke, Ischemic | Angina Pectoris, Stable

China
Makerere University

Completed

Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units

Sepsis | Septic Shock | Acute Liver Failure | Head Injury | Post-cardiac Surgery | Post-Cardiorespiratory Arrest Coma | Hypoxic Brain Damage | Diabetic Ketoacidotic Hyperglycaemic Coma
Rigshospitalet, Denmark
University College, London

Enrolling by invitation

EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV (EuroSIDA)

End Stage Liver Disease | Cardiovascular Diseases | Fractures, Bone | Diabetes Mellitus | Renal Insufficiency | Hepatitis B | Hepatitis C | Kidney Failure, Chronic | Proteinuria | HIV | Coinfection | Acidosis, Lactic | AIDS

Spain, Switzerland, Germany, United Kingdom, Austria, Sweden, Finland, Israel, Denmark, France, Italy, Iceland, Belgium, Slovakia, Norway, Lithuania, Portugal, Poland, Croatia, Czechia, Greece, Hungary, Luxembourg, Argentina, Belarus, Bosnia... and more
Universitaire Ziekenhuizen KU Leuven
Norwegian Institute of Public Health; KU Leuven; University Ghent; Sciensano

Completed

Evidence-based Laboratory Test Order Sets in Primary Care

Liver Diseases | Cardiovascular Diseases | Sexually Transmitted Diseases | Hypertension | Obesity | Diabetes Mellitus | Fatigue | Chronic Kidney Diseases | Thyroid Diseases | Rheumatoid Arthritis | Diarrhea | Anemia | Acute Coronary Syndrome | Gout | Lung Embolism | Medication Monitoring | General Check-up

Belgium
Bayer

Completed

Study on the Safety of BAY1817080 How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given to Participants With Moderate Renal Impairment and End Stage Renal Disease Requiring Dialysis Compared With Matched Participants With Normal Renal Function

Overactive Bladder | Diabetic Neuropathic Pain | Endometriosis Related Pain | Refractory or Unexplained Chronic Cough

United States
Emory University
National Cancer Institute (NCI)

Withdrawn

Tocilizumab for the Treatment of Cytokine Release Syndrome in Patients With COVID-19 (SARS-CoV-2 Infection)

Coronary Artery Disease | Diabetes Mellitus | Chronic Obstructive Pulmonary Disease | Cerebrovascular Accident | Chronic Renal Failure | Malignant Neoplasm | SARS Coronavirus 2 Infection

United States
Brigham and Women's Hospital
The Thompson Family Foundation Inc

Completed

Rural Hospital-Level Care at Home for Acutely Ill Adults

Heart Failure | Infections | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Anticoagulation | Gout Flare | Hypertensive Urgency | Atrial Fibrillation Rapid | Diabetes and Its Complications | End of Life/Desires Only Medical Management

United States, Canada
Duke University
Sanofi; Regeneron Pharmaceuticals

Completed

Patient and Provider Assessment of Lipid Management Registry (PALM)

Smoking | Stroke | Hypertension | Cardiovascular Disease | Diabetes | Peripheral Arterial Disease | Atherosclerosis | Carotid Stenosis | Hypercholesterolemia | Hyperlipidemia | Claudication | Unstable Angina | Coronary Artery Disease (CAD) | Chronic Kidney Disease (CKD) | Angina | Transient Ischemic Attack (TIA) | Myocardial...

United States
Barts & The London NHS Trust

Terminated

CGM (Continuous Glucose Monitoring) Use in Diagnosis of Spontaneous and Reactive Hypoglycaemia

Insulin Resistance | Insulinoma | Hypoglycemia Unawareness | Hypoglycemia Non-Diabetic | Insulin Hypoglycemia | Hypoglycemia, Reactive | Hypoglycaemia Night | Insulinoma; Malignant, Pancreas | Spontaneous Hypoglycemia | Neuro Endocrine Tumours

United Kingdom
University of Tennessee
Sponsor GmbH

Recruiting

Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence (MedAAAction)

Depression | Coronary Artery Disease | Stroke | Hypertension | Diabetes | Chronic Kidney Diseases | Anxiety | Chronic Lung Disease | Pulmonary Embolism | Congestive Heart Failure | Arrythmia | Heart Attack | High Cholesterol/Hyperlipidemia

United States
National Taiwan University Hospital

Unknown

Heidelberg In Vivo Confocal Microscopy to Evaluate the Ocular Surface Disorders of Healthy and Diseased Individuals

Hypertension | Diabetes | Dementia | Alzheimer Disease | Fabry Disease | Dry Eye Syndrome | Metabolic Disease | Healthy Individuals | Ocular Rosacea | Limbal Insufficiency | Phlyctenulosis | Graft Versus Host Disease in Eye

Taiwan
Advice Pharma Group srl

Recruiting

KidneYou - Innovative Digital Therapy

Diabetes | Chronic Kidney Diseases | Tuberous Sclerosis | Albuminuria | Treatment Adherence | Arterial Hypertension | Treatment Adherence and Compliance | Nephronophthisis | Polycystic Kidney | Chronic Glomerulonephritis | Cystic Kidney Diseases | Cortical Cystic Disease | Cystic Diseases

Italy
Complejo Hospitalario Universitario de Albacete
University of Warwick; University Hospitals Coventry and Warwickshire NHS Trust and other collaborators

Not yet recruiting

An Integrated Solution for Sustainable Care for Multimorbid Elderly Patients With Dementia (CAREPATH)

Behavioral Symptoms | Coronary Artery Disease | Heart Failure | Stroke | Hypertension | Diabetes | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Malnutrition | Asthma | Dementia | Alzheimer Disease | Frailty | Sarcopenia | Comorbidities and Coexisting Conditions

Spain
University of Calgary
Alberta Health services; University of Alberta

Completed

Evaluating Innovations in Transition From Pediatric to Adult Care - The Transition Navigator Trial (TNT)

Stroke | Epilepsy | Autoimmune Diseases | Endocrine System Diseases | Diabetes | Hematologic Diseases | Genetic Diseases, Inborn | Traumatic Brain Injury | Autism Spectrum Disorder | Respiratory Disease | Cardiac Disease | Metabolic Disease | Renal Disease | Neuro-Degenerative Disease | Fetal Alcohol Spectrum Disorders | Gastro-Intestinal Disorder

Canada
Eurasian Association of Therapists

Completed

Analysis of Health Status of Сomorbid Adult Patients With COVID-19 Hospitalised in Fourth Wave of SARS-CoV-2 Infection (ACTIV4)

Myocardial Infarction | Stroke | COVID-19 | Diabetes Mellitus | Chronic Kidney Diseases | Ischemic Stroke | Anemia | Atrial Fibrillation | Asthma | Myocarditis | Ischemic Heart Disease | Chronic Heart Failure | Copd | Overweight and Obesity | Pulmonary Embolism | Oncology | Arrythmia | DVT | Hypertensive Heart Disease

Russian Federation
Kaiser Permanente
Garfield Memorial Fund

Completed

Multidisciplinary Inpatient Palliative Care Intervention

Liver Failure | Acquired Immunodeficiency Syndrome | Stroke | Pneumonia | Diabetes Mellitus | Cancer | Pulmonary Disease, Chronic Obstructive | Respiratory Failure | Renal Failure | Dementia | Kidney Failure, Chronic | Coronary Arteriosclerosis | Cerebrovascular Accident | Failure to Thrive | Heart Failure, Congestive

United States
Russian Federation of Anesthesiologists and Reanimatologists
Kuban State Medical University

Recruiting

The Role of Concomitant Diseases in Postoperative Complications Risk Stratification. (STOPRISK)

Stroke | Epilepsy | Diabetes | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Neuromuscular Diseases | Parkinson's Disease | Anemia | Coronary Heart Disease | Chronic Heart Failure | Alzheimer's Disease | Bronchial Asthma | Heart Rhythm Disorders

Russian Federation
University of Washington
National Institute on Aging (NIA)

Active, not recruiting

Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2) (PICSI-H)

Liver Cirrhosis | Quality of Life | Lung Neoplasms | Neoplasm Metastasis | Pulmonary Disease, Chronic Obstructive | Dementia | Kidney Failure, Chronic | Chronic Disease | Peripheral Vascular Disease | Lung Diseases, Interstitial | Health Communication | Heart Failure，Congestive | Patient Care | Health Care Quality... and other conditions

United States
GlaxoSmithKline

Completed

Cancer in Patients With Gabapentin (GPRD)

Epilepsy | Renal Cell Carcinoma | Diabetes | Stomach Cancer | Cancer | Breast Cancer | Pancreatic Cancer | Bladder Cancer | Chronic Pancreatitis | Renal Cancer | Anal Cancer | Renal Pelvis Cancer | Pain, Neuropathic | Nervous System Cancer | Penis Cancer | Bone and Joint Cancer
University of Missouri-Columbia
National Library of Medicine (NLM)

Completed

Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow

Depression | HIV Infections | Hypertension | Obesity | Diabetes Mellitus | Back Pain | Urinary Incontinence | Irritable Bowel Syndrome | Insomnia | Asthma | Anxiety | Sinusitis | Shoulder Pain | Allergic Rhinitis | Urinary Tract Infection | Vaginitis | Bursitis | Hyperlipidemia | Esophageal Reflux | Benign Prostatic Hypertrophy | Osteoporosis... and other conditions

United States
CES University

Recruiting

Essential Hypotension and Allostasis Registry (ESSENTIAL)

Depression | Diabetes Mellitus | Cancer | Atrial Fibrillation | Fibromyalgia | Blood Pressure | Syncope | Coronary Heart Disease | Chronic Fatigue Syndrome | Panic Attack | Diastolic Heart Failure | POTS | Systolic Heart Failure | Vasovagal Syncope | Acute Myocardial Infarction (AMI) | Transient Ischemic Attack (TIA) | Acute... and other conditions

Colombia
University of Washington
National Institute on Aging (NIA)

Completed

Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1) (PICSI-H)

Liver Cirrhosis | Neoplasm Metastasis | Pulmonary Disease, Chronic Obstructive | Dementia | Kidney Failure, Chronic | Chronic Disease | Peripheral Vascular Disease | Lung Diseases, Interstitial | Health Communication | Lung Neoplasm | Heart Failure，Congestive | Patient Care | Health Care Quality, Access, and Evaluation and other conditions

United States
Future Genetics Limited

Recruiting

EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality

Depression | Cardiovascular Diseases | Heart Failure | Epilepsy | Hypertension | Obesity | Diabetes Mellitus | Cancer | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Rheumatoid Arthritis | Peripheral Arterial Disease | Atrial Fibrillation | Asthma | Dementia | Blood Pressure | Coronary Heart Disease | Mental... and other conditions

United Kingdom
Brigham and Women's Hospital

Unknown

Study of an Intervention to Improve Problem List Accuracy and Use (MAPLE)

Coronary Artery Disease | Stroke | Glaucoma | Hypertension | Diabetes | Breast Cancer | Renal Insufficiency | Hemophilia | Hypothyroidism | Asthma | Renal Failure | Hyperthyroidism | Osteoporosis | Myasthenia Gravis | Sickle Cell Disease | Osteopenia | COPD | Congestive Heart Failure | Attention Deficit Disorder With Hyperactivity

United States
Assistance Publique - Hôpitaux de Paris
National Research Agency, France

Completed

Phenomics in Autoimmune and Inflammatory Diseases (TRANSIMMUNOM)

Rheumatoid Arthritis | Uveitis | Vasculitis | Type 1 Diabetes | Crohn's Disease | Myositis | Healthy Volunteer | Ankylosing Spondylitis | FMF | Systemic Lupus Erythematosus/Antiphospholipid Syndrome | Cryopyrin-Associated Periodic Syndromes /TNF-receptor Associated Periodic Syndrome | Ulcerative Rectocolitis | Unclassified...

France
University of Washington
National Institute on Aging (NIA)

Recruiting

Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers (PICSI-M)

Liver Cirrhosis | Quality of Life | Neoplasm Metastasis | Pulmonary Disease, Chronic Obstructive | Peripheral Vascular Diseases | Dementia | Kidney Failure, Chronic | Chronic Disease | Lung Diseases, Interstitial | Health Communication | Lung Neoplasm | Heart Failure，Congestive | Patient Care | Health Care Quality... and other conditions

United States
Université de Sherbrooke
Canadian Institutes of Health Research (CIHR); Western University, Canada; Agence...

Completed

Patient-Centred Innovations for Persons With Multimorbidity - Quebec (PACEinMM-QC)

Depression | Heart Failure | Stroke | Hypertension | Cardiovascular Disease | Diabetes | Ulcer | Cancer | Arthritis | Rheumatoid Arthritis | Musculoskeletal Pain | Asthma | Gastroesophageal Reflux | Dementia | Anxiety | HIV | Crohn's Disease | Osteoporosis | Ulcerative Colitis | Chronic Obstructive Pulmonary Disease (COPD) | Hyperlipi... and other conditions

Canada
Lawson Health Research Institute
University Health Network, Toronto; Sunnybrook Health Sciences Centre; Canadian... and other collaborators

Completed

Patient-Centred Innovations for Persons With Multimorbidity - Ontario (PACEinMM-ON)

Depression | Heart Failure | Stroke | Hypertension | Cardiovascular Disease | Diabetes | Ulcer | Cancer | Arthritis | Rheumatoid Arthritis | Musculoskeletal Pain | Asthma | Gastroesophageal Reflux | Dementia | Anxiety | HIV | Crohn's Disease | Osteoporosis | Ulcerative Colitis | Chronic Obstructive Pulmonary Disease (COPD) | Hyperlipi... and other conditions

Canada

Clinical Trials on Monogenic Diabetes

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Austria

Conditions

Rare Diseases

Drug Interventions

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