Clinical Trials on Mucopolysaccharidosis Type I

Total 56885 results

Future University in Egypt

Completed

Accuracy of LeFort I Osteotomy Fixation Using Two Plates Versus Four Plates Patient Specific Osteosynthesis

Le Fort; I

Egypt
Roxane Laboratories

Completed

Crossover Bioequivalence Study of Quetiapine Fumarate 300 mg Tablets Under Steady State Fasted Conditions

Bipolar I Disorder

United States
Eli Lilly and Company

Completed

A Comparison of Olanzapine in Combination With a Mood Stabilizer vs Mood Stabilizer Alone, in Mixed Bipolar Patients

Bipolar I Disorder

United States
Shire

Completed

A Safety and Dose Ranging Study of Idursulfase (Intrathecal) Administration Via an Intrathecal Drug Delivery Device in Pediatric Patients With Hunter Syndrome Who Have Central Nervous System Involvement and Are Receiving Treatment With Elaprase®

Hunter Syndrome

United States, United Kingdom
Joanne Kurtzberg, MD
The Marcus Foundation

Recruiting

UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells (DUOC-01)

Mucopolysaccharidosis II | Brain Diseases, Metabolic, Inborn | Adrenoleukodystrophy | Batten Disease | Leukodystrophy, Metachromatic | Leukodystrophy, Globoid Cell | Alpha-Mannosidosis | Tay-Sachs Disease | Pelizaeus-Merzbacher Disease | Sandhoff Disease | Neimann Pick Disease | Sanfilippo Mucopolysaccharidoses

United States
Bayer

Completed

Study in Postmenopausal Women to Investigate the Drug-drug Interaction (DDI) Between Itraconazole(ITZ) and Orally Administered Vilaprisan; Absolute Bioavailability Using Intravenous Microtracer Dose of [14C]Vilaprisan

Clinical Trial, Phase I

United Kingdom
University Hospital, Basel, Switzerland

Completed

Pharmacokinetic Study to Characterize Phenotyping Metrics of the "Basel" Cocktail After CYP Induction or Inhibition

Metabolic Detoxication, Phase I

Switzerland
Mansoura University

Active, not recruiting

Compartive Evalution of the Efficiency of Maxillary Canine Retraction Using Power Chain Versus Burstone T-loop

Class I Malocclusion

Egypt
Shire

Completed

An Observational Study Evaluating Anti-Idursulfase Serum Antibody Response in Hunter Syndrome Patients

Hunter Syndrome

United Kingdom, United States, Brazil
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Early Check: Expanded Screening in Newborns

Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions

United States
Cairo University

Not yet recruiting

Evaluation of Resin Composite Posterior Restorations Using Modeling Resin Insertion Technique in Class I Lesions

Class I Composite Restorations
Hvidovre University Hospital
Zealand University Hospital; Steno Diabetes Center Copenhagen

Recruiting

Pathophysiology of Diabetic Gastroparesis (PATODIAG)

Gastroparesis Due to Diabetes Mellitus Type I

Denmark
Bayer

Completed

Drug-drug Interaction Study: Influence of Vilaprisan on Pharmacodynamics (PD) and Pharmacokinetics (PK) of a Combined Oral Contraceptive (COC)

Clinical Trial ,Phase I

Germany
Bayer

Completed

Study in Healthy Young Women to Investigate the Pharmacodynamics, Pharmacokinetics and Safety of Vilaprisan

Clinical Trial, Phase I

Germany
Allergy Therapeutics

Completed

Assessment of the Contribution of Monophosphoryl Lipid A (MPL) to a Grass Pollen Allergy Vaccine

Type I Hypersensitivity

Canada
Postgraduate Institute of Dental Sciences Rohtak

Completed

Effect of Systemic Administration of Vitamin D on the Rate of Orthodontic Tooth Movement - A Randomized Control Trial

Angle Class I

India
Allergy Therapeutics

Completed

Assessment of the Contribution of Monophosphoryl Lipid A (MPL) to a Tree Pollen Allergy Vaccine

Type I Hypersensitivity

Canada
Abramson Cancer Center of the University of Pennsylvania
Massachusetts General Hospital

Completed

Proton Radiotherapy for Stage I, IIA, and IIB Seminoma

Stage I, IIA and IIB Seminoma

United States
Fundació Institut de Recerca de l'Hospital de la...
Spanish Clinical Research Network - SCReN; Grupo de Bioingenieria y Telemedicina...

Completed

Individualized Telemedical Assistance for Lifestyle Modification in the Treatment of Obesity and Cardiometabolic Risk Prevention (PREDIRCAM 2)

Obesity Type I and II

Spain
University of Nebraska
Bristol-Myers Squibb

No longer available

Prospective Analysis and Comparison of Stress Echo to Real-Time Myocardial Contrast Stress Echo

Evaluation of Troponin I Levels

United States
Roxane Laboratories

Completed

Crossover Bioequivalence Study of Quetiapine Fumarate 25 mg Tablets Under Fasted Conditions

Treatment for Bipolar I Disorder

United States
University of British Columbia

Terminated

Treatment of Type I Supracondylar Fractures of the Humerus

Type I Supracondylar Fracture of the Humerus

Canada
Allergy Therapeutics

Completed

Investigation of Efficacy and Safety of Ragweed MATAMPL, Pollinex-R and Placebo in Patients With Ragweed Allergy

Type I Hypersensitivity

Canada
S.LAB (SOLOWAYS)
Center of New Medical Technologies; Triangel Scientific

Completed

Evaluating the Impact of Omega-3 Fatty Acid Supplementation (Soloways™) on Lipid Profiles in Adults With PPARG Polymorphisms (SOLIPARG)

LDL Hyperlipoproteinemia | Low-Density-Lipoprotein-Type [LDL] Hyperlipoproteinemia | Triglyceride Storage Type I or II Disease

Russian Federation
Bayer

Completed

Rogaratinib (BAY1163877) Human Mass Balance Study

Pharmacokinetics | Clinical Trial, Phase I

Netherlands
Rocket Pharmaceuticals Inc.
California Institute for Regenerative Medicine (CIRM)

Completed

A Clinical Trial to Evaluate the Safety and Efficacy of RP-L201 in Subjects With Leukocyte Adhesion Deficiency-I

Leukocyte Adhesion Defect - Type I

Spain, United States, United Kingdom
Rocket Pharmaceuticals Inc.

Withdrawn

A Gene Therapy Trial to Evaluate the Safety and Efficacy of RP-L201 in Subjects With Leukocyte Adhesion Deficiency-I

Leukocyte Adhesion Defect - Type I

Spain
Novartis Pharmaceuticals

Terminated

Extension to a Randomized, Double-blind, Placebo Controlled Study of LCQ908 in Subjects With Familial Chylomicronemia Syndrome.

Familial Chylomicronemia Syndrome (FCS) (HLP Type I)

South Africa, Germany, United Kingdom, France, United States, Canada, Netherlands
Takeda

Recruiting

Extension Study of Idursulfase-IT Along With Elaprase in Children and Adults With Hunter Syndrome and Cognitive Impairment

Hunter Syndrome

Canada, France
Alkermes, Inc.

Completed

Phase 1 Study of OLZ/SAM in Pediatric Subjects With Bipolar I Disorder

Bipolar I Disorder

United States
Bayer

Completed

First in Human Study in Healthy Volunteers to Investigate the Safety, Tolerability and Pharmacokinetics of BAY1214784

Clinical Trials, Phase I as Topic

Germany
University of British Columbia
AstraZeneca; Ozmosis Research Inc.

Recruiting

SCION: SABR and Checkpoint Inhibition Of NSCLC (SCION)

Carcinoma, Non-Small-Cell Lung | Lung Cancer | Non Small Cell Lung Cancer | Non-small Cell Lung Cancer Stage I | Lung Cancer Stage I | Lung Adenocarcinoma, Stage I | Lung Squamous Cell Carcinoma Stage I

Canada
Assistance Publique - Hôpitaux de Paris

Active, not recruiting

Optimizing Response to Li Treatment Through Personalized Evaluation of Individuals With Bipolar I Disorder: The R-LiNK Initiative (R-LiNK)

Bipolar I Disorder

France
Forest Laboratories

Completed

Long-Term Safety Extension Trial of Asenapine in Bipolar 1 Disorder Participants Who Completed Protocol P05691 (P05692)

Bipolar I Disorder

United States
Jina Pharmaceuticals Inc.
Novum Pharmaceutical Research Services; Lambda Therapeutic Research Ltd.; Intas...

Recruiting

Evaluate Efficacy and Safety of Endoxifen in Bipolar I Disorder Patients

Bipolar I Disorder

United States
ZandA Technologies, llc
KGK Science Inc.

Completed

The Efficacy and Safety of an Amino Acid Supplement in Adults

Healthy | Insulin-Like Growth Factor I

Canada
Kafrelsheikh University

Completed

Ridge Splitting With Simultaneous Implant Placement Using i-PRF

Dental Implant | Ridge Splitting | i-PRF

Egypt
Sumitomo Pharma Co., Ltd.

Completed

A Long-Term Study of SM-13496 in Patients With Bipolar I Disorder.

Bipolar I Disorder

Japan, Lithuania, Malaysia, Philippines, Russian Federation, Slovakia, Taiwan, Ukraine
Bayer

Completed

BAY 1902607: Single Dose Escalation, Safety and Tolerability, Pharmacokinetics, Bioavailability, Food Effect

Clinical Trials, Phase I as Topic

Germany
Bayer

Completed

First in Human Study to Investigate the Safety and Tolerability, Pharmacokinetics, Itraconazole Drug-drug-interaction and Food Effect of BAY1817080

Clinical Trials, Phase I as Topic

Germany
Eunice Kennedy Shriver National Institute of Child...

Completed

Cultivating Healthy Environments in Families With Type 1 Diabetes (CHEF)

Type I Diabetes

United States
Ohio State University
Natreon, Inc.

Completed

Effects of Capros in Patients With Type-1 Diabetes (CarposT1D)

Type I Diabetes

United States
National Institute of Diabetes and Digestive and...

Completed

Assessment of Beta Cell Mass in Type 1 Diabetes With 11C-Dihydrotetrabenazine and PET Scan

Type I Diabetes

United States
Hompesch, Marcus, M.D.
Profil Institute for Clinical Research, Inc.

Unknown

PK/PD Study of Intranasal Insulin in Type I Diabetes

Type 1 Diabetes

United States
The Fourth Affiliated Hospital of Anhui Medical...

Completed

Precise Gene Signature for Predicting Outcomes in PDAC

Stage I-II Pancreatic Ductal Adenocarcinoma (PDAC) | Precise Prognostic and Predictive Signature

China
Diatranz Otsuka Limited

Completed

Open-label Investigation of the Safety and Effectiveness of DIABECELL(R) in Patients With Type I Diabetes Mellitus

Type 1 Diabetes

New Zealand
Migal Galilee Research Institute
Ziv Medical Center

Unknown

Selective Immunotargeting of Pathogenic CD8 T Cells of Type 1 Diabetes Patients

Type I Diabetes

Israel
New York Medical College

Completed

Human Placental-Derived Stem Cell Transplantation (HPDSC)

Mucopolysaccharidosis I | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Niemann-Pick Disease | Mucopolysaccharidosis VI | Wolman Disease | Adrenoleukodystrophy | Batten Disease | Metachromatic Leukodystrophy | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Fucosidosis | Gaucher... and other conditions

United States
Nationwide Children's Hospital

Terminated

Impaired Family Dynamics Leads to Non Compliance in Type I Diabetes

Type 1 Diabetes

United States
Centre hospitalier de l'Université de Montréal...
Maisonneuve-Rosemont Hospital

Recruiting

Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal Melting (CXL-KPro)

Corneal Melting in Boston Keratoprosthesis Type I

Canada

Clinical Trials on Mucopolysaccharidosis Type I

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