Clinical Trials on Mucopolysaccharidosis III-A in Belgium

Total 327 results

BioMarin Pharmaceutical
ICON plc

Completed

A Multicenter, Multinational, Observational Morquio A Registry Study (MARS) (MARS)

Mucopolysaccharidosis IV Type A | Morquio A Syndrome | MPS IVA

United States, United Kingdom, Australia, Taiwan, Belgium, Malaysia, Austria, Canada, Portugal, France, Ireland, Czechia, Denmark, Italy, Netherlands, Poland, Puerto Rico
Denali Therapeutics Inc.

Enrolling by invitation

An Extension Study of the Long-Term Safety, Tolerability, and Efficacy of Tividenofusp Alfa (DNL310) in Participants With Mucopolysaccharidosis Type II (MPS II) From Study DNLI-E-0002 or Study DNLI-E-0007

Mucopolysaccharidosis II

United States, Canada, Belgium, Czechia, Netherlands
Denali Therapeutics Inc.

Recruiting

A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric Participants With Neuronopathic (nMPS II) or Non-Neuronopathic Mucopolysaccharidosis Type II (nnMPS II) (COMPASS)

Mucopolysaccharidosis II

United States, Spain, United Kingdom, Czechia, France, Canada, Italy, Belgium, Netherlands, Germany, Argentina, Sweden, Turkey, Colombia, Brazil
BioMarin Pharmaceutical

Completed

Mucopolysaccharidosis (MPS) VI Clinical Surveillance Program (CSP)

Mucopolysaccharidosis VI (MPS VI, Maroteaux-Lamy Syndrome)

United States, France, Australia, Germany, Ireland, Austria, Belgium, Italy, Lithuania, Netherlands, Portugal, Sweden, United Kingdom
Genzyme, a Sanofi Company

Recruiting

Mucopolysaccharidosis I (MPS I) Registry

Mucopolysaccharidosis I (MPS I)

Croatia, United States, Argentina, Australia, Belgium, Brazil, Canada, Denmark, France, Hong Kong, India, Indonesia, Korea, Republic of, Kuwait, Lebanon, Malaysia, Netherlands, Pakistan, Philippines, Poland, Saudi Arabia, Singapore, Slovaki... and more
Comunicare Solutions SA
KU Leuven; Jessa Hospital; Cliniques universitaires Saint-Luc- Université Catholique... and other collaborators

Recruiting

Implementation and Cost-evaluation of a Smartphone-based Telemonitoring and Digital Support in Patients With HF (BEDICARE-HF)

Heart Failure | Heart Failure NYHA Class II | Heart Failure NYHA Class III | Heart Failure NYHA Class IV

Belgium
Celyad Oncology SA

Completed

C-Cure Clinical Trial

Heart Failure Class II or III

Belgium, Serbia
University Hospital, Ghent

Completed

Primary Birmingham Hip Resurfacing Arthroplasty Using a Metal-on-Metal Couple in the Young Active Patient

Indications for a Total Hip Prosthesis

Belgium
Erasme University Hospital

Completed

Minimal Optimal Dose of Sugammadex in Elective Surgery

Time of a TOF Ratio >0,9

Belgium
University Hospital, Ghent

Completed

Primary Ceramic-on-Ceramic Total Hip Replacement Versus Metal-on-Metal Hip Resurfacing in Young Active Patients

Indications for a Total Hip Prosthesis

Belgium
University Ghent
Federal Agency for Nuclear Control, Belgium

Completed

Low Dose Effects of X-rays in Pediatric Patients Undergoing a CT Examination. (PedCTBe)

Pediatric Patients Undergoing a Computed Tomography Examination

Belgium
Brugmann University Hospital

Completed

Are the Fried Criteria Predictive of a Functional Decline in Older People With Solid Malignant Tumors?

Elderly Patients With a Solid Tumor

Belgium
Cliniques universitaires Saint-Luc- Université...
Université Catholique de Louvain

Completed

Effect of a Specific Aquaporin-1 Inhibitor on Vascular Oxidative Stress in Healthy Volunteers (Bacoxy_II)

Cardiovascular Diseases | Endothelial Dysfunction | Oxidative Stress | Bacopaside II | Bacopa Monnieri | Aquaporin 1 | AQP1

Belgium
University Hospital, Ghent
Centre Hospitalier Universitaire Vaudois; University Ghent; Hopital Lariboisière and other collaborators

Completed

PIPAC Nab-pac for Stomach, Pancreas, Breast and Ovarian Cancer (PIPAC-nabpac)

Breast Cancer Stage IV | Peritoneal Carcinomatosis | Ovarian Cancer Stage IIIC | Ovarian Cancer Stage IV | Breast Cancer Stage IIIB | Breast Cancer Stage IIIc | Ovarian Cancer Stage IIIB | Stomach Cancer Stage III | Stomach Cancer Stage IV With Metastases | Pancreas Cancer, Stage III | Pancreas Cancer, Stage...

Belgium
AZ-VUB

Unknown

An Explorative Study of Afatinib in the Treatment of Advanced Cancer Carrying an EGFR, a HER2 or a HER3 Mutation

Cancers Harbouring an EGFR Mutation, (Excluding Non-squamous Non- Small Cell Lung Cancer, a Registered Indication), a HER2 Mutation or a HER3 Mutation

Belgium
Universitaire Ziekenhuizen KU Leuven

Completed

Test-retest Reliability of a Standard Protocol on the Biodex Dynamometer

Test-retest Reliability | Validity | Biodex Medical Systems III Dynamometer | Experimental Measure of Knee Extension Strength

Belgium
Universitaire Ziekenhuizen KU Leuven

Completed

SecurAcath Versus Statlock for PICC Securement (SecurAstaP)

Patients With Any Condition Who Need a PICC for IV Therapy

Belgium
University Hospital, Ghent

Completed

Pathophysiological Mechanisms of Hepatopulmonary Influence in the Fontan Circulation

Children With a Univentricular Heart Undergoing Surgery for Creation of a Fontan Circulation

Belgium
Endotronix, Inc.

Active, not recruiting

SIRONA Trial Heart Failure NYHA Class III

Heart Failure NYHA Class III

Belgium, Ireland
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGN

C3 Glomerulopathy | C3 Glomerulonephritis | Dense Deposit Disease | Immune Complex Mediated Membranoproliferative Glomerulonephritis | Membranoproliferative Glomerulonephritis Types I, II, and III

Netherlands, Australia, Belgium
PXL University College

Completed

Feasibility Study of i-ACT in Aged Persons (i-ACT-aged)

Feasibility of a Technology-based System in Aged Person

Belgium
Universitair Ziekenhuis Brussel

Recruiting

Predictive Modelling of the Intraoperative Train-of-Four (TOF) Ratio

Analyse Neuromuscular Monitoring for Developing a Model to Predict TOF Ratio During Anesthesia

Belgium
Cliniques universitaires Saint-Luc- Université...

Completed

Impact of Conservative Treatment by Custom-made Orthoses in Patients With Haemophilic Ankle Arthropathy

Haemophilia A | Haemophilia B

Belgium
Jules Bordet Institute

Recruiting

Neoadjuvant Regorafenib in Combination With Nivolumab and Short-course Radiotherapy in Stage II-III Rectal Cancer (REGINA)

Rectal Cancer Stage II | Rectal Cancer Stage III

Belgium, France
General Hospital Groeninge

Completed

Predictive Value of the Distress Thermometer as a Predictive Screening Instrument to Detect Cancer-related Cognitive Impairment in Cancer Patients (CONCEPT)

Cognitive Impairment | Cancer Patients Eligible for a Treatment With Curative Intent

Belgium
Endotronix, Inc.

Active, not recruiting

SIRONA 2 Trial Heart Failure NYHA Class III

Heart Failure NYHA Class III

Ireland, Belgium, Germany
Cliniques universitaires Saint-Luc- Université...

Withdrawn

Functional and Clinical Impact of CYP3A Genetic Polymorphisms on Statin Therapy

Patients With High Cholesterol Levels Needing a Lipid-lowering Therapy

Belgium
GlaxoSmithKline

Withdrawn

Evaluation of the Long-term Persistence of Hepatitis A Antibodies in Healthy Adults Who Were Vaccinated 21-25 Years Earlier With GlaxoSmithKline (GSK) Biologicals' Hepatitis A Vaccine, Havrix®

Hepatitis A

Belgium
GlaxoSmithKline

Completed

Long-Term Immune Persistence of GlaxoSmithKline Biologicals' Inactivated Hepatitis A Vaccine, Injected According to 0, 6-month Schedule

Hepatitis A

Belgium
GlaxoSmithKline

Completed

Long-Term Immune Persistence of GlaxoSmithKline Biologicals' Inactivated Hepatitis A Vaccine Injected According to a 0, 12-month Schedule

Hepatitis A

Belgium
Universitair Ziekenhuis Brussel

Recruiting

A Clinical Trial of Regorafenib in Patients With Pretreated Advanced Melanoma (RegoMel)

Melanoma Stage IV | Melanoma Stage III

Belgium
Universitair Ziekenhuis Brussel

Completed

TraMel-WT: A Trial of Trametinib in Patients With Advanced Pretreated BRAFV600 Wild-type Melanoma (TraMel-WT)

Stage IV Melanoma | Stage III Melanoma

Belgium
Crucell Holland BV

Completed

Safety and Immunogenicity of a Paediatric Dose of Virosomal Hepatitis A Vaccine

Hepatitis A

Belgium
Universitair Ziekenhuis Brussel
RIZIV

Completed

mRNA Electroporated Autologous Dendritic Cells for Stage III/IV Melanoma (DC-MEL)

Malignant Melanoma Stage III | Malignant Melanoma Stage IV

Belgium
Bart Neyns
Vrije Universiteit Brussel

Completed

Autologous TriMix-DC Therapeutic Vaccine in Combination With Ipilimumab in Patients With Previously Treated Unresectable Stage III or IV Melanoma (TriMix-Ipi)

Malignant Melanoma Stage III | Malignant Melanoma Stage IV

Belgium
KU Leuven

Completed

NMES in Critically Ill Patients (NESCI)

Critically Ill Patients With a Predicted Prolonged ICU Stay

Belgium
Universitair Ziekenhuis Brussel

Not yet recruiting

Belgian Antithrombin Deficiency Registry

Antithrombin III Deficiency

Belgium
Immune Targeting Systems Ltd

Completed

Safety and Reactogenicity of a H1N1 Influenza Challenge Virus in Healthy Volunteers

Influenza A

Belgium
IDEWE Occupational Health Services
GlaxoSmithKline

Unknown

Twinrix Alternative Schedule Study

Antibody Response After Vaccination

Belgium
Ziekenhuis Oost-Limburg

Unknown

Effect of Bone-anchored Protraction on Maxillary Growth in the Young Child

Maxillary Hypoplasia | Malocclusion, Angle Class III

Belgium
European Organisation for Research and Treatment...
Breast International Group; Menarini Group

Recruiting

Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA) (TREAT ctDNA)

Stage IIB Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast Cancer | Stage III Breast Cancer

Belgium, Italy, Ireland, France, Germany
Brugmann University Hospital

Completed

Prevalence and Screening of Hepatitis C in Belgium in 2015

Hepatitis C

Belgium
Janssen Research & Development, LLC

Completed

A Study to Assess the Relative Oral Bioavailability of JNJ-63623872 Administered as Oral Concept Formulations Compared to the Current Tablet Formulation

Influenza A Virus

Belgium
Tibotec Pharmaceuticals, Ireland

Completed

TMC647055HPC1001 - First-in-human Trial to Examine Safety, Tolerability and Pharmacokinetics (How the Drug is Absorbed Into the Bloodstream) of Increasing Single Oral Doses and of Increasing Repeated Oral Doses of TMC647055 in Healthy Volunteers and in Hepatitis C Virus Infected Patients

Hepatitis C

Belgium
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
GlaxoSmithKline

Completed

Long-term Persistence Study in Healthy Adults Previously Vaccinated With Twinrix Adult

Hepatitis B | Hepatitis A

Belgium
GlaxoSmithKline

Completed

Long-Term Immune Persistence of GSK Biologicals' Combined Hepatitis A & B Vaccine Injected According to a 0,6 Month Schedule

Hepatitis B | Hepatitis A

Belgium
GlaxoSmithKline

Completed

Evaluation of Immunogenicity, Reactogenicity and Safety of HBV-MPL Vaccine vs Engerix™-B, in Haemodialysis Patients

Hepatitis B

Belgium
GlaxoSmithKline

Completed

Immunogenicity and Reactogenicity of MPL Adjuvanted Recombinant Hepatitis B- Vaccine and Engerix™-B in Adult Non-Responders

Hepatitis B

Belgium
GlaxoSmithKline

Completed

Antibody Persistence & Immune Memory in Healthy Adults Previously Vaccinated With Twinrix Adult

Hepatitis B | Hepatitis A

Belgium

Clinical Trials on Mucopolysaccharidosis III-A in Belgium

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