Clinical Trials on Mucosal Melanoma of the Head and Neck

Total 14361 results

University of Pittsburgh

Withdrawn

Pharmacodynamic Effects and Predictive Biomarkers With Ruxolitinib in Operable Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma
Memorial Sloan Kettering Cancer Center
Genentech, Inc.

Completed

Bevacizumab, Cetuximab, and Cisplatin With IMRT (Intensity-Modulated Radiation Therapy) for Patients With Stage III/IV Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer

United States
NantBioScience, Inc.

Active, not recruiting

QUILT-2.025 NANT Neoepitope Yeast Vaccine (YE-NEO-001): Adjuvant Immunotherapy Using a Personalized Neoepitope Yeast-Based Vaccine To Induce T-Cell Responses In Subjects W/ Previously Treated Cancers.

Melanoma | Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Liver Cancer

United States
GlaxoSmithKline

Recruiting

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma (JADE)

Neoplasms, Head and Neck

United States, Italy, Japan, Norway, Spain, Taiwan, Australia, United Kingdom, Belgium, Brazil, Germany, Greece, Romania, Sweden, Turkey, Canada, Korea, Republic of, China, France, Argentina, India, Poland, Israel, Portugal, Mexico, Czechia, Hunga...
Lund University Hospital

Recruiting

a Multicentre Phase III Study of Risk-based Treatment Intensification With Hyperfractionated Radiotherapy in Head and Neck Cancer Patients (ARTSCAN VI)

Head and Neck Squamous Cell Carcinoma

Sweden
Tianjin Medical University Cancer Institute and...

Recruiting

A Single-center Phase II Study to Investigate the Immune Maintenance Therapy Pattern in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma Who Have Achieved MPR After Neoadjuvant Immunotherapy Combined With Chemotherapy

Head and Neck Cancer

China
ALX Oncology Inc.
Merck Sharp & Dohme LLC

Recruiting

Evorpacept (ALX148) in Combination With Pembrolizumab in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-03)

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma

United States, Korea, Republic of, United Kingdom, Spain, Belgium, Singapore, Canada, Netherlands, Australia
M.D. Anderson Cancer Center

Active, not recruiting

A Pilot Study of Glutamine PET Imaging of Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma

United States
Case Comprehensive Cancer Center

Completed

Temporally Feathered Radiation Therapy (TFRT) for Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer

United States
Massachusetts General Hospital
Merck Sharp & Dohme LLC; AperiSys, Inc

Withdrawn

AMD3100 Plus Pembrolizumab in Immune Checkpoint Blockade Refractory Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer

United States
Hoffmann-La Roche

Completed

A Study of Pharmacodynamics of RO5083945 in Patients With Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer

Spain, France, United Kingdom, Netherlands, Italy
Seoul National University Hospital
Clinical Research Center for Solid Tumor, Korea

Completed

Cetuximab as Induction Treatment in Head and Neck Squamous Cell Carcinoma (HNSCC)

Head and Neck Neoplasm

Korea, Republic of
All India Institute of Medical Sciences, New Delhi

Unknown

Accelerated Fractionation Radiotherapy (AFRT) Versus Concurrent Chemoradiotherapy (Crt) In Locally Advanced Head And Neck Squamous Cell Carcinoma

HEAD AND NECK CANCER

India
Brian Gastman

Active, not recruiting

Neoadjuvant-Adjuvant Pembrolizumab in Resectable Advanced Basal Cell Carcinoma of H&N

Basal Cell Carcinoma of the Head and Neck

United States
Xiang Lu

Recruiting

Neoadjuvant Tislelizumab Plus Chemotherapy for Resectable Locally-advanced Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinomas | Resectable Head and Neck Squamous-cell Carcinoma

China
Memorial Sloan Kettering Cancer Center
Celgene Corporation; National Comprehensive Cancer Network

Completed

Weekly Nanoparticle Albumin-Bound Paclitaxel (Abraxane) + Weekly Cetuximab + Radiation Therapy (IMRT, Intensity-Modulated Radiation Therapy) in Patients With Stage III-IVB Head and Neck Squamous Cell Carcinoma (HNSCC)

HEAD & NECK Cancer

United States
National Cancer Institute (NCI)

Completed

Cetuximab With or Without Tivantinib in Treating Patients With Head and Neck Cancer That Is Recurrent, Metastatic, or Cannot Be Removed by Surgery

Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Carcinoma

United States
Mario Negri Institute for Pharmacological Research
Aventis Pharmaceuticals; Istituto Scientifico Romagnolo per lo Studio e la... and other collaborators

Completed

Intergroup Trial of Adjuvant Chemotherapy in Adenocarcinoma of the Stomach (ITACA-S)

Adenocarcinoma of the Gastroesophageal Junction | Adenocarcinoma of the Stomach

Italy
Cliniques universitaires Saint-Luc- Université...

Recruiting

Activity and Safety of Peptide-based Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck. (HN1901)

Oropharynx Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma | Hypopharynx Squamous Cell Carcinoma | Larynx Squamous Cell Carcinoma

Belgium
Ipsen

Terminated

Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1.

Gastric Cancer | Colorectal Cancer | Bone Cancer | Squamous Cell Carcinoma of the Head and Neck | Advanced Cancer | Recurrent Disease | Pancreatic Ductal Adenocarcinoma | Metastatic Tumours

United States, France, Belgium, Switzerland, Netherlands
Orthopedic Hospital Vienna Speising

Completed

Predictive Factors for the Development of Osteonecrosis After the Treatment of the Developmental Dislocated Hip

Predictors of Osteonecrosis of the Femoral Head After Treatment of the Dislocated Hip

Austria
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb

Completed

Preoperative Immune Checkpoint Inhibitor for Patients With Primary Untreated or Recurrent/Metastatic SCCHN

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Head and Neck Cancer Metastatic

United States
University of Pittsburgh
National Cancer Institute (NCI); University of Arizona

Completed

Effects of Avmacol® in the Oral Mucosa of Patients Following Curative Treatment for Tobacco-related Head and Neck Cancer

Carcinoma in Situ | Head and Neck Cancer | Hyperplasia | Head and Neck Carcinoma | Dysplasia | Head and Neck | Head and Neck Squamous Cell Carcinoma (HNSCC) | Tobacco-Related Carcinoma | Premalignant Lesion

United States
Ezra Cohen
The V Foundation for Cancer Research

Recruiting

Window of Opportunity Study of IPI-549 in Patients With Locally Advanced HPV+ and HPV- Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer | HPV-Related Malignancy | Head and Neck Squamous Cell Carcinoma | Head and Neck Carcinoma | HPV-Related Carcinoma | HPV-Related Squamous Cell Carcinoma | Head and Neck Cancer Stage IV | Head and Neck Cancer Stage III

United States
Shi Yuankai

Recruiting

Study of Pembrolizumab Combined With Anlotinib in the First Line Therapy for R/M HNSCC With CPS≥1

Head and Neck Squamous Cell Carcinoma

China
Sun Yat-sen University
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Neoadjuvant Camrelizumab in Combination With Cisplatin and Nab-paclitaxel in Resectable HNSCC

Head and Neck Squamous Cell Carcinoma

China
Xinqiao Hospital of Chongqing
TCRCure Biopharma Ltd.

Recruiting

EBV-Specific Anti-PD1 TCR-T Cells in the Treatment of EBV-Positive NHSCC

Head and Neck Squamous Cell Carcinoma

China
Groupe Oncologie Radiotherapie Tete et Cou

Active, not recruiting

Stereotactic Radiotherapy Combined With Chemotherapy or Not for Treatment of Oligometastases in HNSCC (OMET)

Head and Neck Squamous Cell Carcinoma

France
Sanofi
Groupe Oncologie Radiotherapie Tete et Cou

Completed

TRACE: Tirapazamine-Radiation And Cisplatin Evaluation (TRACE)

Head and Neck Squamous Cell Carcinoma

United States, France, Canada, Poland, Germany, Spain, Switzerland, Singapore, Taiwan, Argentina, Hungary, Italy, Chile, Hong Kong, South Africa, Australia, New Zealand
Centre Leon Berard
The Biostatistics and Therapy Evaluation Unit

Completed

Protocole Advanced RadioTherapy ORL (ART-ORL)

Head and Neck Squamous Cell Carcinoma

France
National Cancer Institute (NCI)

Terminated

Sunitinib, Cetuximab, and Radiation Therapy in Treating Patients With Locally Advanced or Recurrent Squamous Cell Carcinoma of the Head and Neck

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
BioNTech SE

Recruiting

A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1 (AHEAD-MERIT)

Recurrent Head and Neck Cancer | Unresectable Head and Neck Squamous Cell Carcinoma | Metastatic Head and Neck Cancer

Germany, United States, France, United Kingdom, Korea, Republic of, Spain, Poland, Belgium, Brazil, Taiwan, Italy, Canada, Czechia, Australia, Turkey, Mexico, Chile, Argentina, Austria, Hungary, Portugal, Sweden
University of Washington
National Cancer Institute (NCI)

Terminated

Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing Nausea and Vomiting Caused by Cisplatin in Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy

Nausea and Vomiting | Stage III Squamous Cell Carcinoma of the Hypopharynx | Stage III Squamous Cell Carcinoma of the Larynx | Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage III Squamous Cell Carcinoma of the Nasopharynx | Stage III Squamous Cell Carcinoma of the Oropharynx and other conditions

United States
M.D. Anderson Cancer Center
Cancer Prevention Research Institute of Texas

Recruiting

Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Laryngeal Cancer

Squamous Cell Carcinoma of the Larynx | Malignant Neoplasms of Respiratory and Intrathoracic Organs

United States
University Health Network, Toronto

Recruiting

HN-QUEST: A Study of Head and Neck Imaging Biomarkers (HN-Quest)

Head and Neck Squamous Cell Carcinoma

Canada
Universität des Saarlandes

Recruiting

Pembrolizumab and Lenvatinib After Definitive Chemoradiation of Locally Advanced HNSCC

Head and Neck Squamous Cell Carcinoma

Germany
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb

Recruiting

Neoadjuvant Targeting of Myeloid Cell Populations in Combination With Nivolumab in Head & Neck Ca (Spark2)

Head and Neck Squamous Cell Carcinoma

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Neoadjuvant Toripalimab or Toripalimab in Combination With Carboplatin and Nab-paclitaxel in Untreated HNSCC (HNSCC-002)

Head and Neck Squamous Cell Carcinoma

China
Shanghai Ninth People's Hospital Affiliated to...
Fudan University; First Affiliated Hospital of Fujian Medical University; Tianjin... and other collaborators

Recruiting

Concurrent Immunotherapy With Postoperative Radiotherapy in Intermediate/High Risk HNSCC Patients Unfit for Cisplatin: The IMPORT Study (IMPORT) (IMPORT)

Head and Neck Squamous Cell Carcinoma

China
AIO-Studien-gGmbH
Roche Pharma AG

Completed

Explorative Phase II Study of Perioperative Treatment in Patients With Adenocarcinoma of the Gastroesophageal Junction or Stomach (HerFLOT)

Adenocarcinoma of the Gastroesophageal Junction | Adenocarcinoma of the Stomach

Germany
National Cancer Institute (NCI)

Completed

Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent Cetuximab

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
Roswell Park Cancer Institute

Recruiting

Intensive Symptom Surveillance Guided by Machine Learning-Directed Risk Stratification in Patients With Non-Metastatic Head and Neck Cancer, The INSIGHT Trial

Head and Neck Squamous Cell Carcinoma

United States
Barzilai Medical Center

Unknown

The Oral Microbiome as a Prognostic Tool in Oral Malignant and Premalignant Lesions and in Medication Related Osteonecrosis of the Jaw

Oral Squamous Cell Carcinoma | Medication Related Osteonecrosis of the Jaw | Oral Epithelial Dysplasia

Israel
University of Liege

Completed

Controlled Study of Stage 3 Osteonecrosis Treatment by Bone Marrow

Non Traumatic Osteonecrosis of the Femoral Head (Hip)

Belgium
Chase Heaton, MD
Incyte Corporation; OncoSec Medical Incorporated

Terminated

Optimizing Antitumor Immunity Using Plasmid Electroporation, Pembrolizumab, and Epacadostat

Recurrent Head and Neck Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Unresectable Head and Neck Squamous Cell Carcinoma

United States
Amsterdam UMC, location VUmc
MRIguidance B.V.

Completed

MRI-based Synthetic CT Images of the Head and Neck

Sinusitis | Hearing Loss | Head and Neck Tumor | Cholesteatoma | Imaging of Bony Structures of the Head (Various Conditions)

Netherlands
David Travis Thomas

Completed

Randomized Study of Beet Root in Locally Advanced Squamous Cell Cancer of the Head and Neck

Mucositis

United States
OHSU Knight Cancer Institute
Oregon Health and Science University; Cambia Health Foundation

Recruiting

The Use of "Smart" Body-Weight Scales for Weight and Nutritional Monitoring in Patients With Head and Neck Cancer Undergoing Radiation Therapy

Head and Neck Squamous Cell Carcinoma | Malignant Head and Neck Neoplasm

United States
Cancer Trials Ireland
Southampton Clinical Trials Unit; Region H Rigshospitalet; Centre Hospitalier...

Completed

NEOadjuvant Trial in Adenocarcinoma of the oEsophagus and oesophagoGastric Junction International Study (Neo-AEGIS)

Oesophageal Cancer | Adenocarcinoma of the Oesophagus | Adenocarcinoma of the Oesophago-gastric Junction | Oesophageal Tumours | Junctional Tumours

Ireland, United Kingdom, Denmark, France, Sweden
Hoffmann-La Roche

Completed

A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)

Breast Cancer | Solid Tumor | Cancer of Head and Neck

Spain, United States, Belgium, Denmark, France, United Kingdom, Canada, Netherlands, Italy

Clinical Trials on Mucosal Melanoma of the Head and Neck

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