Clinical Trials on Multidrug Resistant Bacterial Infection

Total 8852 results

Human Biome Institute S.A.

Recruiting

Fecal Microbiota Transplantation (FMT) to Decolonize Antibiotic - Resistant Bacteria (ARB) - New Protocol (STOP-ARB2)

Antimicrobial Drug Resistance | Drug Resistance, Bacterial

Poland
Erasmus Medical Center
Radboud University Medical Center; National Institute for Public Health and... and other collaborators

Not yet recruiting

Quinolone Resistance Profiles and Mechanisms of Staphylococcus Aureus and Escherichia Coli From Humans, Chicken and Catfish Farms in Indonesia (QUINDO)

Drug Resistance, Microbial
José Raimundo Araujo de Azevedo

Not yet recruiting

Risk Factors for Multidrug Resistant Bacteria at ICU Admission

Multi Drug Resistant Bacteria
GlaxoSmithKline

Completed

Dose-Ranging Study of GSK2140944 in the Treatment of Subjects With Suspected or Confirmed Gram-Positive Acute Bacterial Skin and Skin Structure Infections

Infections, Bacterial

United States
University of Alabama at Birmingham

Terminated

Early Versus Expectant Treatment of Ureaplasma Infection in Very Low Birth Weight Neonates

Respiratory Tract Infections | Bacteria Infection

United States
Institut d'Investigació Biomèdica de Bellvitge
UMC Utrecht; Tel Aviv University; University of Bristol; AiCuris Anti-infective...

Completed

Study to Assess Management and Outcomes of Hospitalised Patients With Complicated UTI (RESCUING) (RESCUING)

Urinary Tract Infections | Bacterial Resistance

Israel, Spain, Greece, Italy, Bulgaria, Hungary, Romania, Turkey
Novartis
Novartis Vaccines

Completed

Immune Response Induced by a Vaccine Against Group B Streptococcus and Safety in Pregnant Women and Their Offsprings

Bacterial Infection | Streptococcal Infection | Gram-positive Bacterial Infection

Belgium, Canada
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Recruiting

Evaluating a Novel Individualised Treatment Strategy for Carbapenem-Resistant Gram-Negative Bacteria Infections

Antibiotic Therapy

Singapore
The University of Queensland
Merck Sharp & Dohme LLC

Withdrawn

Ceftolozane-tazobactam Versus Meropenem for ESBL and AmpC-producing Enterobacterales Bloodstream Infection (MERINO III)

Bacteremia Caused by Gram-Negative Bacteria

Spain, Australia, Singapore, Italy, Saudi Arabia
Assistance Publique - Hôpitaux de Paris
Commissariat A L'energie Atomique; EIT Health; NG Biotech

Completed

AMR-DetecTool for the Diagnostic of MDR Bacterial Infections (AMR DetecTool)

Bacterial Sensitivity Tests | Antimicrobial Drug Resistance

France, Hungary, Spain
Ruijin Hospital
Pfizer

Unknown

Linezolid Alone or Combined With Carbapenem Against Methicillin-resistant Staphylococcus Aureus (MRSA) in Ventilator-associated Pneumonia

Pneumonia, Ventilator-Associated | Methicillin-resistant Staphylococcus Aureus
Melinta Therapeutics, LLC

Recruiting

Study to Evaluate the Safety and Tolerability of Single-Dose Intravenous (IV) Oritavancin

Acute Bacterial Skin and Skin Structure Infection

United States, Spain, Greece, Portugal, Bulgaria, Latvia, Romania, Lithuania, Poland
Aziende Chimiche Riunite Angelini Francesco S.p.A
Hippocrates Research

Completed

Retrospective Effectiveness Study of Dalbavancin and Other Standard of Care of the Same Class in Patients With ABSSSI (REDS)

Acute Bacterial Skin and Skin Structure Infection

Greece, Italy
Miquel Pujol
Hospital Universitari de Bellvitge

Completed

Efficacy of Daptomycin Plus Fosfomycin Versus Daptomycin for Treatment of MRSA Bacteremia

Staph Aureus Methicillin Resistant Bacteremia

Spain
Assistance Publique Hopitaux De Marseille

Unknown

Therapeutic Drug Monitoring of Anti-infectious Drugs in Intensive Care Unit (STP-ATB-REA)

Infection, Bacterial
National University of Singapore
Pfizer; Biomerieux inc

Recruiting

EaRly impAct theraPy With Ceftazidime-avibactam Via rapID Diagnostics (RAPID)

Hospital-acquired Pneumonia | Ventilator Associated Pneumonia | Healthcare Associated Infection | Blood Stream Infections | Carbapenem-Resistant Enterobacteriaceae Infection

Taiwan, Malaysia, Thailand
University of Duhok

Not yet recruiting

Parenteral Versus Combined Parenteral With Vancomycin-soaked Graft in ACL Reconstruction

Infection, Bacterial
Melinta Therapeutics, Inc.
Department of Health and Human Services

Completed

Pharmacokinetics and Safety of Solithromycin in Adolescents and Children

Bacterial Infection

United States, Bulgaria
Ministry of Health, Rwanda

Unknown

A Trial Assessing Efficacy of Various Antimicrobial Techniques for Reducing Bacterial Load (RMC-11)

Disease Due to Gram-positive Bacteria

Rwanda
Hospices Civils de Lyon

Completed

Staphylococcus Lugdunensis Prosthetic Joint Infection

Staphylococcal Infections | Prosthetic Joint Infection

France
Mayo Clinic
Ortho-McNeil, Inc.

Completed

The Utility of Levofloxacin-Rifampin in the Therapy of Prosthetic Joint Infection

Staphylococcal Infection | Staphylococcus Aureus Prosthetic Joint Infection

United States
Phramongkutklao College of Medicine and Hospital
Silpakorn University

Recruiting

Dose Optimization by Pharmacokinetic/Pharmacodynamic of Antibiotics to Improve Clinical Outcome of Carbapenem Resistant Klebsiella Pneumoniae Bloodstream Infections in Critically Ill Patients at Phramongkutklao Hospital

Carbapenem Resistant Klebsiella Pneumoniae

Thailand
Jena University Hospital

Terminated

PERFORM = Pentaglobin® Registry For Outcome Report and Monitoring (PERFORM)

Severe Bacterial Infection

Brazil, Colombia, Germany, Turkey
Shanghai Public Health Clinical Center

Unknown

Acquired Immunodeficiency Syndrome(AIDS) and Tuberculosis(Tb) Co-infection Treatment Strategies Study of China.

AIDS

China
Pfizer
Allergan

Terminated

Evaluation of Pharmacokinetics, Safety, and Tolerability of Ceftazidime-avibactam in Neonates and Infants. (NOOR)

Gram-negative Bacterial Infection

United States, Hungary, Slovakia, Taiwan, India, Estonia, Greece, Italy
Pfizer

Completed

Safety, Pharmacokinetics (PK) and Tolerability Study of a Novel Drug for Treatment of Bacterial Infections

Gram-negative Bacterial Infection

Australia
Assiut University

Not yet recruiting

Frequency of h.Pylori in Children With Dyspeptic Symptoms

H.Pylori Infection
GlaxoSmithKline

Terminated

Evaluation of the Safety, Tolerability and Pharmacokinetics of Repeat Oral Doses of GSK580416

Infections, Bacterial | Bacterial Infection

Australia
Haiphong University of Medicine and Pharmacy

Completed

Comparison of Efficacy of Two Combination Regimens for the Neisseria Gonorrhoeae and Chlamydia Coinfection

Chlamydia Trachomatis Infection | Neisseria Gonorrhoeae Infection

Vietnam
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Skin Infections

Skin Diseases, Bacterial

Hong Kong, Korea, Republic of, United States, Philippines, Singapore, Canada, Thailand, Israel, Taiwan, Lebanon, Malaysia, South Africa
Arpida AG

Completed

Study of Intravenous (I.V.) Iclaprim Versus Linezolid in Complicated Skin and Skin Structure Infections [cSSSI] (ASSIST-2)

Skin Diseases, Bacterial

United States
GlaxoSmithKline

Completed

Drug-drug Interaction Study of Gepotidacin

Infections, Bacterial

United States
GlaxoSmithKline
Biomedical Advanced Research and Development Authority

Completed

Pharmacokinetics (PK) Study of Gepotidacin (GSK2140944) in Adult Subjects With Varying Degrees of Hepatic Impairment and in Matched Control Subjects With Normal Hepatic Function

Infections, Bacterial

United States
GlaxoSmithKline

Terminated

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Ascending Intravenous Single Dose and Repeat Dose of GSK3342830

Infections, Bacterial

Australia
GlaxoSmithKline

Completed

Relative Bioavailability Study in Healthy Subjects (PDF112034)

Infections, Bacterial

United States
GlaxoSmithKline

Completed

A Repeat Dose Escalation Study to Investigate the Safety, Tolerability and Pharmacokinetics of GSK1322322 in Healthy Subjects

Infections, Bacterial

Australia
University of California, San Francisco
London School of Hygiene and Tropical Medicine; National Heart, Lung, and Blood... and other collaborators

Completed

GeneXpert Performance Evaluation for Linkage to Tuberculosis Care (XPEL-TB)

Tuberculosis, Pulmonary | Rifampicin Resistant Tuberculosis

Uganda
GlaxoSmithKline

Completed

Pharmacokinetics of Gepotidacin Tablets in Adults and Adolescents Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Terminated

A Three-part Study to Determine the Safety, Tolerability and Pharmacokinetics of GSK1322322 in Healthy Volunteers and Healthy Male Japanese Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

Amoxicillin Bioequivalence Study Brazil - Fast

Infections, Bacterial

Brazil
GlaxoSmithKline

Withdrawn

A Pharmacokinetics, Pharmacodynamics, and Safety Study of an Oral Contraceptive Containing Norethindrone and Ethinyl Estradiol When Co-administered With GSK1322322 in Healthy Adult Women

Infections, Bacterial
GlaxoSmithKline

Completed

GSK1322322 Versus Linezolid in the Treatment of Acute Bacterial Skin and Skin Structure Infection

Skin Infections, Bacterial

United States
Seoul National University Bundang Hospital

Recruiting

The Efficacy of the 7 Days Tailored Therapy as the 1st Eradication of H. Pylori Infection

Helicobacter Infection

Korea, Republic of
Seoul National University Bundang Hospital

Terminated

The Efficacy of the 7 Days Tailored Therapy as 2nd Rescue Therapy for Eradication of H. Pylori Infection

Helicobacter Infection

Korea, Republic of
Beijing Chest Hospital
National Medical Center for Infectious Diseases

Recruiting

Innovating Shorter, All- Oral, Precised, Individualized Treatment Regimen for Rifampicin Resistant Tuberculosis：Contezolid, Delamanid and Bedaquiline Cohort (INSPIRE-CODA)

Pulmonary Tuberculosis | Rifampicin-resistant Tuberculosis

China
TD Vaccines A/S
Johns Hopkins University; University of Vermont; SNBL Clinical Pharmacology Center... and other collaborators

Unknown

ACE393-103 Vaccination Challenge Study (ACE393-103VC)

Campylobacter Infection

United States
Thallion Pharmaceuticals
LFB Biotechnologies, SAS

Completed

Study of Chimeric Monoclonal Antibodies to Shiga Toxins 1 and 2

Shiga Toxin Producing Bacterial Infection

Argentina, Peru, Chile
The University of Hong Kong

Recruiting

Emergency PWAS in Respiratory Infectious Disease

Pneumonia | Sepsis | Bacterial Infections | Viral Infections | Fungal Infections | Mycobacterium Infection | Mixed Infection | Infection of Uncertain Aetiology

China
University of North Carolina, Chapel Hill

Completed

Initial and Chronic Methicillin Resistant Staphylococcus Aureus (MRSA) Infection in Cystic Fibrosis (CF) (TRI-STAR)

Cystic Fibrosis | Methicillin-Resistant Staphylococcus Aureus

United States
University Hospital, Clermont-Ferrand
University Hospital, Estaing; Hopital Gabriel Montpied

Unknown

Assessment of the Prevalence of Extended-Spectrum Betalactamase Producing Enterobacteriaceae Among ICU Staff (REASSE)

Antibiotic Resistance | Extended-spectrum Betalactamase | Enterobacteriaceae | Escherichia Coli

France

Clinical Trials on Multidrug Resistant Bacterial Infection

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