Clinical Trials on Multiple Primary Neoplasm

Total 149836 results

University of California, San Francisco
United States Department of Defense

Recruiting

Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy (ReVIVE)

Multiple Sclerosis, Chronic Progressive | Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis (MS) | Multiple Sclerosis Relapse | Multiple Sclerosis, Primary Progressive | Multiple Sclerosis Brain Lesion | Multiple Sclerosis Benign

United States
Icahn School of Medicine at Mount Sinai
Columbia University; New York Stem Cell Foundation Research Institute

Completed

Mitochondrial Dysfunction and Disease Progression

Clinically Isolated Syndrome | Relapsing-Remitting Multiple Sclerosis | Primary Progressive Multiple Sclerosis | Secondary Progressive Multiple Sclerosis

United States
The Cleveland Clinic

Withdrawn

Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Treating Patients With Multiple Myeloma

Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Refractory Plasma Cell Neoplasm

United States
MediciNova
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes... and other collaborators

Completed

Safety, Tolerability and Activity Study of Ibudilast in Subjects With Progressive Multiple Sclerosis

Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive

United States
M.D. Anderson Cancer Center

Active, not recruiting

Overall and Disease Specific Survival in Patients With Confirmed MEN1 With or Without PNET (Pancreatic Neuroendocrine Tumors)

Genetic Mutation | MEN1

United States
LAPIX Therapeutics Inc.

Recruiting

An Observational Biomarker Study in Multiple Sclerosis (MS) Patients

Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive

United States
University of Regina
University of Saskatchewan; Saskatchewan Health Research Foundation; First Steps...

Recruiting

Exercise Effects in Multiple Sclerosis

Multiple Sclerosis | Multiple Sclerosis, Chronic Progressive | Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive

Canada
Guangxi Medical University

Recruiting

EUS-FNI for MEN1-related Pancreatic Neuroendocrine Tumors

Pancreatic Neuroendocrine Tumor | Multiple Endocrine Neoplasia Type 1

China
National Cancer Institute (NCI)

Completed

Ziv-Aflibercept in Treating and Computed Tomography Perfusion Imaging in Predicting Response in Patients With Pancreatic Neuroendocrine Tumors That Are Metastatic or Cannot Be Removed by Surgery

Pancreatic Neuroendocrine Carcinoma | Multiple Endocrine Neoplasia Type 1

United States
Atara Biotherapeutics

Terminated

Phase 1/2 Study to Evaluate the Safety and Efficacy of ATA188 in Subjects With Progressive Multiple Sclerosis (EMBOLD)

Primary Progressive Multiple Sclerosis | Secondary Progressive Multiple Sclerosis

United States, Australia, Canada
Emmanuelle Waubant, MD PhD
United States Department of Defense

Recruiting

Neuroprotection With N-acetyl Cysteine for Patients With Progressive Multiple Sclerosis (NACPMS)

Multiple Sclerosis | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive

United States
Rennes University Hospital

Recruiting

Motor Asymmetry in Progressive Multiple Sclerosis Patients (MAP-MS)

Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive

France
University Hospital, Antwerp
Hasselt University; University Hospital, Ghent; AZ Sint-Jan AV; National MS Center... and other collaborators

Recruiting

Metformin Add-on Clinical Study in Multiple Sclerosis to Evaluate Brain Remyelination And Neurodegeneration

Multiple Sclerosis | Primary Progressive Multiple Sclerosis | Secondary-progressive Multiple Sclerosis

Belgium
National Cancer Institute (NCI)

Completed

Sorafenib Tosylate in Treating Patients With Metastatic, Locally Advanced, or Recurrent Medullary Thyroid Cancer

Multiple Endocrine Neoplasia Type 2A | Multiple Endocrine Neoplasia Type 2B | Recurrent Thyroid Gland Medullary Carcinoma | Hereditary Thyroid Gland Medullary Carcinoma | Locally Advanced Thyroid Gland Medullary Carcinoma | Sporadic Thyroid Gland Medullary Carcinoma | Stage III Thyroid Gland Medullary... and other conditions

United States
University of South Florida
Boston Children's Hospital

Completed

Access to Resources for Patients With PTEN Hamartoma Tumor Syndrome

PTEN Gene Mutation

United States
Association de Recherche Bibliographique pour les...
Centre Hospitalier Universitaire de Nice; Centre Hospitalier Princesse Grace

Completed

Social Cognition in Multiple Sclerosis, From a Study of Eye Movement and Gaze Strategies Using Video-oculography (EYE-SEP)

Healthy | Clinically Isolated Syndrome | Multiple Sclerosis (MS) | Radiologically Isolated Syndrome | Multiple Sclerosis (MS) Relapsing Remitting | Multiple Sclerosis (MS) Primary Progressive | Multiple Sclerosis (MS) Secondary Progressive

Monaco
Leonardo A. Peyré-Tartaruga
Aline Nogueira Haas; Flávia Gomes Martinez

Not yet recruiting

MUSCLE - Nordic Walking in MUltiple SCLErosis (MUSCLE)

Multiple Sclerosis | Multiple Sclerosis, Chronic Progressive | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive

Brazil
University of Massachusetts, Lowell
Ohio State University

Completed

Video Game-based Therapy for Arm Weakness In Progressive Multiple Sclerosis

Hemiparesis | Primary Progressive Multiple Sclerosis

United States
National Cancer Institute (NCI)

Completed

Sirolimus to Treat Cowden Syndrome and Other PTEN Hamartomatous Tumor Syndromes

Hamartoma Syndrome, Multiple | Cowden's Disease

United States
Rigshospitalet, Denmark
Danish Research Centre for Magnetic Resonance

Unknown

The Effects of Erythropoietin on Clinical Disability and Brain Pathology in Patients With Progressive Multiple Sclerosis (EPO-ProgMS)

Multiple Sclerosis (Primary or Secondary Progressive Phase).

Denmark
Stanford University
Kyverna Therapeutics

Recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subjects With Non-relapsing and Progressive Forms of Multiple Sclerosis

Multiple Sclerosis | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive

United States
Margarida Magalhaes-Silverman
National Cancer Institute (NCI)

Completed

Autologous Stem Cell Transplant Followed By Maintenance Therapy in Treating Elderly Patients With Multiple Myeloma

Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Primary Systemic Amyloidosis | Light Chain Deposition Disease | Extramedullary Plasmacytoma | Isolated Plasmacytoma of Bone

United States
Oncotherapeutics

Withdrawn

Melphalan, Arsenic Trioxide, and Ascorbic Acid in Treating Patients With Relapsed or Refractory Multiple Myeloma

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Refractory Plasma Cell Neoplasm

United States
John Carroll University
University Hospital Southampton NHS Foundation Trust

Active, not recruiting

Development and Validation of an Online Neurobehavioral Evaluation Tool for PTEN Patients

PTEN Hamartoma Tumor Syndrome

United States, United Kingdom
Mayo Clinic
National Cancer Institute (NCI)

Completed

Low-Dose Melphalan and Dexamethasone Compared With High-Dose Melphalan Followed By Autologous Stem Cell Transplant in Treating Patients With Primary Systemic Amyloidosis

Multiple Myeloma and Plasma Cell Neoplasm

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Lenalidomide, Cyclophosphamide, and Dexamethasone in Treating Patients With Primary Systemic Amyloidosis

Multiple Myeloma and Plasma Cell Neoplasm

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Melphalan, Thalidomide, and Dexamethasone in Treating Patients With Newly Diagnosed, Previously Untreated Primary Systemic Amyloidosis

Multiple Myeloma and Plasma Cell Neoplasm

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Multiple Myeloma

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Refractory Plasma Cell Neoplasm

United States
The First Affiliated Hospital of Guangzhou Medical...

Unknown

The Efficacy of PD-1 Antibody Sintilimab on Early-stage Multiple Primary Lung Cancer With Ground Glass Density.

Multiple Primary Lung Cancers

China
Han weidong

Unknown

Anti-PD-1 Antibody Alone or in Combination With Decitabine/Chemotherapy in Relapsed or Refractory Malignancies

Malignancies Multiple

China
Shanghai Pulmonary Hospital, Shanghai, China

Recruiting

Efficiency and Safety of Microwave Ablation Plus Immune Checkpoint Inhibitor for Patients With Multiple Primary Lung Cancer: A Open, Multi-center, Phase II Clinical Trial (MAGIC)

Multiple Primary Lung Cancer

China
Ruijin Hospital
The First Affiliated Hospital of Nanchang University; Second Affiliated Hospital... and other collaborators

Recruiting

Treatment of EGFR-TKI for Residual Lesions of Multiple Synchronous Ground-glass Opacities (TERMGGO)

Multiple Primary Lung Cancers

China
The First Affiliated Hospital of Xiamen University

Not yet recruiting

Stereotactic Ablation Radiotherapy Combined With Sintilimab in Early Inoperable Synchronous Multiple Primary Lung Cancer

Multiple Primary Lung Cancer
University Hospital, Rouen

Completed

Targeted Next-generation Sequencing Panel for Identification of Germline Mutations in Early Onset Cancers With Sporadic or Hereditary Presentation (PANEL)

Breast Cancer | Colorectal Cancer | Ovarian Cancer | Pediatric Cancers | Multiple Primary Malignant Tumours

France
Novartis Pharmaceuticals

Active, not recruiting

Special Drug-use Surveillance for Kesimpta for s.c. Injection 20 mg Pen

Relapsing-remitting Multiple Sclerosis | Active Secondary Progressive Multiple Sclerosis

Japan
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

High-Dose Melphalan Plus Peripheral Stem Cell Transplantation in Treating Patients With Primary Systemic Amyloidosis

Multiple Myeloma and Plasma Cell Neoplasm

United States
Herbert Irving Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Chemotherapy Plus Peripheral Stem Cell Transplant in Treating Patients Who Have Multiple Myeloma or Primary Systemic Amyloidosis

Multiple Myeloma and Plasma Cell Neoplasm

United States
National Cancer Institute (NCI)

Completed

4'-Iodo-4'-Deoxydoxorubicin in Treating Patients With Primary Systemic Amyloidosis

Multiple Myeloma and Plasma Cell Neoplasm

United States, Italy
Genzyme, a Sanofi Company

Completed

A Study To Assess ZD6474 (ZACTIMA™) Monotherapy In Locally Advanced or Metastatic Hereditary Medullary Thyroid Cancer

Thyroid Cancer

Italy, Spain, Romania, Netherlands, Canada, United States, Switzerland, Australia
Niels Fristrup
Aarhus University Hospital

Recruiting

Deferred Cytoreductive Nephrectomy in Synchronous Metastatic Renal Cell Carcinoma: The NORDIC-SUN-Trial (NORDIC-SUN)

Kidney Cancer | Renal Cell Carcinoma Metastatic | Synchronous Neoplasm

Denmark
Instituto Nacional de Cancerologia de Mexico

Completed

Radical Treatment of Synchronous Oligometastatic Non-Small Cell Lung Carcinoma

Carcinoma, Non-Small-Cell Lung | Synchronous Neoplasms

Mexico
Stanford University

Not yet recruiting

Sirolimus for Improving Social Abilities in People With PTEN Germline Mutations

PTEN Gene Mutation | PTEN Hamartoma Tumor Syndrome | PTEN Hamartoma Syndrome

United States
Sanofi

Recruiting

A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.

Relapsing Multiple Sclerosis | Secondary Progressive Multiple Sclerosis | Progressive Relapsing Multiple Sclerosis

Belgium
Bristol-Myers Squibb

Completed

A Study to Evaluate the Effect of 2 Drugs on the Pharmacokinetics of BMS-986205 in Healthy Subjects

Malignancies Multiple

United States
University of South Florida
Genentech, Inc.

Active, not recruiting

Upper Extremity Function in Multiple Sclerosis Patients With Advanced Disability Treated With Ocrevus

Pathologic Processes | Nervous System Diseases | Immune System Diseases | Multiple Sclerosis | Demyelinating Diseases | Autoimmune Diseases | Relapsing Remitting Multiple Sclerosis | Primary Progressive Multiple Sclerosis

United States
Novartis Pharmaceuticals

Completed

A Phase I/II Study of BEZ235 in Patients With Advanced Solid Malignancies Enriched by Patients With Advanced Breast Cancer

Breast Cancer | Advanced Solid Tumors | Cowden Syndrome

Netherlands, Spain, Germany, United Kingdom, United States
Radboud University Medical Center

Unknown

Response of Immune System to Flu Vaccination in PHTS (RIPS)

PTEN Hamartoma Tumor Syndrome
Casa Sollievo della Sofferenza IRCCS
Neurocenter of Southern Switzerland; Associazione Revert ONLUS; Fondazione Cellule...

Completed

Safety Study of Human Neural Stem Cells Injections for Secondary Progressive Multiple Sclerosis Patients (NSC-SPMS)

Secondary-progressive Multiple Sclerosis

Italy, Switzerland
Lawson Health Research Institute
The Ottawa Hospital; Hamilton Health Sciences Corporation; Dalhousie University; Niagara Health System

Active, not recruiting

Rivaroxaban or Aspirin As Thromboprophylaxis in Multiple Myeloma (RithMM)

Multiple Myeloma in Relapse | Multiple Myeloma With Failed Remission | Multiple Myeloma Stage I | Multiple Myeloma Progression | Multiple Myeloma Stage II | Multiple Myeloma Stage III

Canada
University College, London
London School of Hygiene and Tropical Medicine; The Leeds Teaching Hospitals... and other collaborators

Active, not recruiting

Multiple Sclerosis-Simvastatin Trial 2 (MS-STAT2)

Secondary Progressive Multiple Sclerosis (SPMS)

United Kingdom

Clinical Trials on Multiple Primary Neoplasm

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Zimbabwe

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

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