Clinical Trials on Multiple Sclerosis in Netherlands

Total 400 results

Radboud University Medical Center

Terminated

The Effect of Intensive Controlled Exercise in the Early Stages of Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Netherlands
Newron Sweden AB

Terminated

A follow-on Study to Assess Long-term Safety and Tolerability of i.c.v Administration of sNN0029 in Patients With ALS

Amyotrophic Lateral Sclerosis

Belgium, Netherlands
UMC Utrecht

Terminated

The Role of Post-traumatic Inhibition of the Innate and Adaptive Immune System in the Development of Infectious Complications in Severely Injured Patients (POSEIDON)

Sepsis | Multiple Trauma | Innate Immune Response | Multiple Organ Dysfunction Syndrome | Disorder of Neutrophils

Netherlands
Newron Sweden AB

Terminated

A Safety Study of sNN0029 Administration Via Intracerebroventricular Route to Patients With ALS

Amyotrophic Lateral Sclerosis

Belgium, Netherlands
Novartis Pharmaceuticals

Completed

Optical Coherence Tomography (OCT) Trial in Multiple Sclerosis (OCTIMS)

Multiple Sclerosis | RRMS

Spain, Czechia, Germany, Australia, Italy, Switzerland, Denmark, United States, United Kingdom, Canada, Netherlands, Poland
AbbVie (prior sponsor, Abbott)

Completed

Safety and Effectiveness of Two Doses of ABT-874 as Compared to Placebo in Subjects With Multiple Sclerosis (MS)

Multiple Sclerosis

United States, Canada, Germany, Netherlands, United Kingdom
UMC Utrecht
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Mesenchymal Stromal Cells as Treatment for Digital Ulcers in Systemic Sclerosis (MANUS)

Systemic Sclerosis | Digital Ulcer

Netherlands
Verge Genomics

Recruiting

A Study of VRG50635 in Participants With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Canada, Netherlands
Biogen

Completed

Efficacy and Safety Study of Prolonged-Release Fampridine in Participants With Multiple Sclerosis (ENHANCE)

Multiple Sclerosis

United States, Finland, Italy, United Kingdom, Bulgaria, Serbia, Russian Federation, Lithuania, Poland, Czech Republic, Netherlands
Radboud University Medical Center

Recruiting

OPTIMA FORMA Phase 3 (OPTIMAFORMA3)

Chronic Conditions, Multiple | Chronic Condition

Netherlands
Genzyme, a Sanofi Company

Active, not recruiting

Efficacy, Safety and Pharmacokinetics of Teriflunomide in Pediatric Patients With Relapsing Forms of Multiple Sclerosis (TERIKIDS)

Multiple Sclerosis

Belgium, United States, Bulgaria, Canada, China, Estonia, France, Greece, Israel, Lebanon, Lithuania, Morocco, Netherlands, Portugal, Russian Federation, Serbia, Spain, Tunisia, Turkey, Ukraine, United Kingdom
Sergiusz Jozwiak
Medical University of Vienna; Charite University, Berlin, Germany; Institut National... and other collaborators

Unknown

Long-term, Prospective Study Evaluating Clinical and Molecular Biomarkers of Epileptogenesis in a Genetic Model of Epilepsy - Tuberous Sclerosis Complex (EPISTOP)

Epilepsy | Tuberous Sclerosis Complex | TSC

Poland, Austria, Belgium, Czech Republic, France, Germany, Italy, Netherlands
Bayer

Completed

Follow-up Study After 11 Years of Patients Who Were Included in the BENEFIT Trial (304747) With a First Demyelinating Event Suggestive of Multiple Sclerosis

Multiple Sclerosis

Belgium, Italy, Spain, France, Switzerland, Israel, Czech Republic, Canada, Austria, Poland, Germany, Netherlands, United Kingdom, Hungary, Portugal, Finland, Norway, Sweden, Slovenia, Denmark
UCB Pharma
Biogen

Terminated

Placebo Controlled Study in Subjects With Relapsing Forms of MS to Evaluate the Safety, Tolerability and Effects of CDP323

Multiple Sclerosis

United States, France, Germany, Spain, Canada, Netherlands, Belgium, Hungary, Sweden, United Kingdom, Finland
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Cognition and HRQoL in Adults With Highly-active RMS in Year 3 and 4 After Initial Mavenclad® Dose (CLARIFY MS Extension)

Multiple Sclerosis

Spain, France, Czechia, Slovakia, Italy, Hungary, Austria, Denmark, Netherlands, Poland
Radboud University Medical Center

Recruiting

EMBOSS A Person-centred Integrated-care for Chronic Diseases in Patients of Low Socio Economic Status (EMBOSS)

Chronic Conditions, Multiple | Chronic Condition

Netherlands
Novartis Pharmaceuticals

Recruiting

The Gilenya Pregnancy Registry

Multiple Sclerosis

Denmark, Spain, Switzerland, United States, Argentina, Australia, Austria, Belgium, Brazil, Canada, Colombia, Cyprus, Czechia, Finland, France, Germany, Greece, Hungary, Ireland, Israel, Italy, Lebanon, Mexico, Netherlands, Norway, Poland, ... and more
Sanofi

Completed

Long Term Safety and Efficacy Study of Teriflunomide 7 mg or 14 mg in Patients With Relapsing-Remitting Multiple Sclerosis

Multiple Sclerosis

United States, Austria, Canada, Chile, Czech Republic, Denmark, Estonia, Finland, France, Germany, Italy, Netherlands, Norway, Poland, Portugal, Russian Federation, Sweden, Switzerland, Turkey, Ukraine, United Kingdom
Bayer

Completed

BENEFIT Study (Betaferon® / Betaseron® in Newly Emerging Multiple Sclerosis for Initial Treatment) and BENEFIT Follow-up Study

Multiple Sclerosis

Belgium, Italy, Spain, France, Germany, Canada, Switzerland, Austria, Denmark, Hungary, Netherlands, Poland, Israel, United Kingdom, Finland, Sweden, Norway, Czech Republic, Portugal, Slovenia
University Medical Center Groningen

Recruiting

Optimizing INITIation of Non-invasive Ventilation in ALS Patients (INITIALS)

Amyotrophic Lateral Sclerosis

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...
University Medical Center Groningen; Erasmus Medical Center; University Hospital... and other collaborators

Completed

A Multicenter, Randomized Study of Early Assessment by CT Scanning in Severely Injured Trauma Patients (REACT-2)

Multiple Trauma/Injuries

Netherlands, Switzerland
Novartis Pharmaceuticals

Recruiting

Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis

Multiple Sclerosis

Italy, Spain, United States, Germany, France, Serbia, Austria, Brazil, Bulgaria, Canada, Croatia, Estonia, Latvia, Mexico, Poland, Puerto Rico, Russian Federation, Sweden, Turkey, Ukraine, United Kingdom, Lithuania, Netherlands, Slovakia and more
Biogen

Completed

Study to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of BIIB033 in Participants With Relapsing Forms of Multiple Sclerosis When Used Concurrently With Avonex (SYNERGY)

Multiple Sclerosis

United States, Spain, Hungary, Serbia, Canada, France, Poland, Russian Federation, Netherlands, Czech Republic, Italy, United Kingdom
Hoffmann-La Roche

Active, not recruiting

This is an Extension Study of the Roche P-trials to Investigate Safety and Effectiveness of Ocrelizumab in Participants With Multiple Sclerosis (MS)

Multiple Sclerosis

Canada, United Kingdom, Belgium, Brazil, Croatia, Mexico, Slovakia, Ireland, Netherlands, Estonia, Norway, Denmark, Italy, Poland, Spain, Bulgaria, France, Turkey, Portugal, Sweden, Argentina, Kuwait, Slovenia, Czechia, Hungary, Finland
The University of Queensland
King's College London; UMC Utrecht; Julius Clinical; FightMND

Completed

Targeting Metabolic Flexibility in Amyotrophic Lateral Sclerosis (ALS) (MetFlex)

Motor Neuron Disease | Amyotrophic Lateral Sclerosis

Netherlands, United Kingdom, Australia
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Safety and Efficacy of Orally Administered Laquinimod Versus Placebo for Treatment of Relapsing Remitting Multiple Sclerosis (RRMS) (ALLEGRO)

Multiple Sclerosis

United States, Austria, Bulgaria, Canada, Czechia, Estonia, France, Georgia, Germany, Hungary, Israel, Italy, Lithuania, Netherlands, Poland, Romania, Russian Federation, Serbia, Spain, Sweden, Turkey, Ukraine, United Kingdom, Latvia
Celgene

Completed

Study of Ozanimod (RPC1063) in Relapsing Multiple Sclerosis (MS) (SUNBEAM)

Multiple Sclerosis

United States, Spain, Czechia, Russian Federation, Portugal, Serbia, United Kingdom, New Zealand, Belarus, Bulgaria, Poland, Romania, Estonia, Germany, Sweden, Ukraine, Hungary, Croatia, Georgia, Bosnia and Herzegovina, Latvia, Li... and more
Retrotope, Inc.

Recruiting

RT001 in Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Netherlands, Estonia, Latvia, Sweden
Sanofi

Completed

An Efficacy Study of Teriflunomide in Participants With Relapsing Multiple Sclerosis (TOWER)

Multiple Sclerosis

Belgium, United States, Australia, Austria, Belarus, Canada, Chile, China, Czech Republic, Estonia, France, Germany, Greece, Mexico, Netherlands, Philippines, Poland, Romania, Slovakia, Spain, Sweden, Thailand, Tunisia, Turkey, Ukraine, United...
Radboud University Medical Center

Unknown

The Effect of High Dose Methylprednisolone on Nailfold in Early Systemic Sclerosis ( SSc )

Systemic Sclerosis | Raynaud Phenomena

Netherlands
Erasmus Medical Center

Not yet recruiting

Hydrocortisone Treatment for Symmetric Lipomatosis Associated With Neuropathy (SLN): an N-of-1 Study Hydrocortisone Treatment for Symmetric Lipomatosis Associated With Neuropathy (SLN): an N-of-1 Study (N-of-1 SLN)

Symmetric Lipomatoses, Multiple

Netherlands
Hoffmann-La Roche

Active, not recruiting

A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis (OLERO)

Multiple Sclerosis

United States, Spain, Austria, Czechia, Italy, Hungary, Australia, Portugal, Serbia, Canada, Germany, United Kingdom, Poland, Romania, Croatia, Israel, Belgium, Bulgaria, Estonia, Switzerland, Mexico, Lithuania, New Zealand, France, Slo... and more
Biogen

Completed

Dimethyl Fumarate (DMF) Observational Study (ESTEEM)

Multiple Sclerosis

United States, Denmark, Italy, Netherlands, Switzerland, Canada, Australia, New Zealand, United Kingdom, Slovakia, Austria, Hungary, Czechia, Portugal, Germany, Spain, Poland, Puerto Rico, France, Argentina, Ireland, Norway
Biogen

Completed

Open-Label Study to Assess the Effect of Long-Term Prolonged-Release Fampridine (BIIB041) on Quality of Life as Reported by Participants With Multiple Sclerosis (ENABLE)

Multiple Sclerosis

France, Italy, United Kingdom, Germany, Australia, Belgium, Netherlands, Portugal, Denmark
Biogen

Terminated

Efficacy and Safety of BIIB033 (Opicinumab) as an Add-on Therapy to Disease-Modifying Therapies (DMTs) in Relapsing Multiple Sclerosis (MS) (AFFINITY)

Multiple Sclerosis

United States, Italy, Spain, Belgium, Germany, Switzerland, Australia, Hungary, France, Poland, United Kingdom, Czechia, Israel, Canada, Netherlands
Actelion

Completed

Bosentan in Systemic Sclerosis (HOME)

Systemic Sclerosis | Digital Ulcers

Netherlands
UMC Utrecht
Prothya Biosolutions

Terminated

Effect of C1-esterase Inhibitor on Systemic Inflammation in Trauma Patients With a Femur or Pelvic Fracture (CAESAR)

Sepsis | Inflammation | Trauma | Multiple Organ Dysfunction Syndrome

Netherlands
UMC Utrecht

Unknown

Probiotics in Patients With Primary Sclerosing Cholangitis

Primary Sclerosing Cholangitis

Netherlands
Maastricht University Medical Center
Stichting Pergamijn (Gouverneur Kremers Centrum/azM); Koraalgroep(Gouverneur... and other collaborators

Unknown

Malnutrition in People With Complex Multiple Disabilities

Malnutrition | Complex Multiple Disabilities

Netherlands
Sanofi
Denali Therapeutics Inc.

Terminated

Study to Evaluate DNL747 in Subjects With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

United States, Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Local Assessment of Management of Burn Patients (LAMiNAR)

Mechanical Ventilation | Burns - Multiple

Netherlands
Amsterdam UMC, location VUmc

Unknown

Effect of Rosiglitazone on ADMA in Critical Illness

Critical Illness | Multiple Organ Failure

Netherlands
Merck KGaA, Darmstadt, Germany

Completed

Evaluation of Quality of Life (QoL) in Subjects With Highly Active Relapsing Multiple Sclerosis (MS) (CLARIFY MS)

Multiple Sclerosis

Hungary, Belgium, Portugal, Slovakia, France, Finland, Poland, Denmark, Czechia, Spain, United Kingdom, Italy, Austria, Greece, Lithuania, Netherlands, Norway, Sweden
Orion Corporation, Orion Pharma

Completed

Effects of ODM-109 on Respiratory Function in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Ireland, Netherlands, United Kingdom, Germany
Washington University School of Medicine
Johns Hopkins University; Massachusetts General Hospital; Columbia University; UMC... and other collaborators

Completed

Understanding Clinical Phenotype and Collecting Biomarker Samples in C9ORF72 ALS

C9ORF72 Amyotrophic Lateral Sclerosis (ALS)

United States, Netherlands
J.M. de Laat
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Recruiting

Precision Radiotherapy Using MR-linac for Pancreatic Neuroendocrine Tumours in MEN1 Patients (PRIME)

Multiple Endocrine Neoplasia Type 1 | Neuroendocrine Tumor of Pancreas

Netherlands
Maastricht University Medical Center

Completed

Effect of Vitamin C in Autologous Stem Cell Transplantations (VICAST)

Lymphoma | Myeloma Multiple

Netherlands
Amsterdam UMC, location VUmc

Completed

Pharmacokinetics of Two Different High-dose Regimens of Intravenous Vitamin C in Critically Ill Patients

Sepsis | Systemic Inflammatory Response Syndrome | Trauma | Multiple Organ Failure

Netherlands
QurAlis Corporation

Recruiting

A Study Evaluating the Safety and Tolerability of QRL-201 in ALS

Amyotrophic Lateral Sclerosis

Canada, Germany, Netherlands, Ireland, United Kingdom, Belgium
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Unknown

L-citrulline Supplementation During Sepsis

Sepsis | Multiple Organ Failure

Netherlands

Clinical Trials on Multiple Sclerosis in Netherlands

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Moldova

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations