Clinical Trials on Muscular Atrophy, Progressive

Total 52425 results

Massachusetts General Hospital
Northwestern University; University of Florida; University of Minnesota; Henry... and other collaborators

Recruiting

ALS/MND Natural History Study Data Repository

ALS | Kennedy Disease | MND (Motor Neurone DIsease) | PLS | PMA - Progressive Muscular Atrophy | PBP - Progressive Bulbar Palsy

United States, Italy
Stem Cells Arabia

Unknown

Autologous Bone Marrow-Derived Stem Cell Therapy for Motor Neuron Disease

Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Progressive Muscular Atrophy | Progressive Bulbar Palsies
St Mary's University College

Not yet recruiting

Blood Flow Restricted Electrical Stimulation During Immobilisation

Atrophy, Muscular | Atrophy, Disuse
United States Army Research Institute of Environmental...

Recruiting

Molecular Mechanisms Underlying Anabolic Resistance to Protein Intake During Muscle Disuse

Muscular Disorders, Atrophic | Muscle Atrophy | Disuse Atrophy | Atrophy, Disuse | Disuse Atrophy Muscle of Thigh

United States
South Dakota State University
Sanford Research

Completed

The Efficacy of Protein Supplementation on Attenuating Muscle Atrophy Following Disuse in the Collegiate Population

Disuse Atrophy

United States
McMaster University

Unknown

n3 PUFA and Muscle-disuse Atrophy in Older Women

Sarcopenia | Muscle Atrophy | Muscle Disuse Atrophy

Canada
McGill University

Recruiting

Examining Sex-based Differences in Metabolic and Mechanistic Responses to Disuse Induced Muscle Atrophy

Muscle Atrophy | Muscle Disuse Atrophy

Canada
McMaster University
University of Guelph

Completed

n3 PUFA and Muscle-disuse Atrophy in Young Women

Muscle Atrophy

Canada
Bispebjerg Hospital

Recruiting

Prehabilitative Exercise Prior to Immobilization (PREHAB)

Sarcopenia | Disuse Atrophy | Skeletal Muscle Atrophy

Denmark
McMaster University

Completed

The Regulation of Human Skeletal Muscle Mass by Contractile Perturbation (HYPAT)

Muscle Atrophy | Disuse Atrophy (Muscle) of Lower Leg

Canada
University of Birmingham

Completed

Can Supplemental Leucine Offset Disuse-induced Muscle Atrophy? (LEU-DIMA)

Muscle Disuse Atrophy

United Kingdom
University of Nottingham
Biotechnology and Biological Sciences Research Council

Unknown

Mechanisms of Disuse Atrophy in Human Skeletal Muscle (iMOB) (iMOB)

Muscular Atrophy | Immobility Syndrome

United Kingdom
University of Exeter

Completed

Muscle Damage and Disuse Atrophy

Muscle Disuse Atrophy

United Kingdom
Hoffmann-La Roche

Completed

Ability of Muscle Imaging and Motor Function Measure (MFM) to Detect Changes in Disease Progression in Ambulant Spinal Muscular Atrophy Patients Compared to Healthy Volunteers.

Healthy Volunteer, Muscular Atrophy, Spinal

Switzerland
Texas Christian University

Recruiting

Strength Training Augmenting Rehabilitation (STAR)

Muscle Disuse Atrophy

United States
Logan College of Chiropractic

Unknown

Short Arc Multifidus Study

Multifidus Disuse Atrophy

United States
McMaster University

Recruiting

The Effects of Protein Supplementation With or Without Urolithin A During Single-leg Immobilization

Healthy | Muscle Disuse Atrophy

Canada
McMaster University
Myos Corporation

Completed

Effect of a Natural Source Supplementation on Muscle Mass

Nutrition, Healthy | Muscle Disuse Atrophy

Canada
Milton S. Hershey Medical Center
BioSensics

Not yet recruiting

Digital Assessment of Speech and Fine Motor Control in ALS

Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Progressive Muscular Atrophy
Duke University
Centers for Disease Control and Prevention; National ALS Registry; Agency for...

Completed

Study of ALS Reversals 4: LifeTime Exposures (StARLiTE)

Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Progressive Muscular Atrophy

United States
University of Sao Paulo

Completed

Leucine Supplementation and Skeletal Muscle Disuse

Disuse Atrophy

Brazil
Duke University
CReATe Consortium (funded by NIH/NCATS/NINDS)

Completed

Study of ALS Reversals 2: Genetic Analyses (StAR2)

Amyotrophic Lateral Sclerosis | Progressive Muscular Atrophy

United States
Opexa Therapeutics, Inc.

Completed

Study of Tcelna (Imilecleucel-T) in Secondary Progressive Multiple Sclerosis (Abili-T)

Multiple Sclerosis | Autoimmune Diseases of the Nervous System | Disease Progression | Secondary Progressive Multiple Sclerosis | Brain Atrophy

United States, Canada
University of Birmingham
University of Nottingham; Biotechnology and Biological Sciences Research Council

Completed

Preventing Bed-rest Induced Muscle Loss in the Elderly

Sarcopenia | Muscle Loss | Prehabilitation | Disuse Atrophy | Protein Metabolism

United Kingdom
University of Alberta
McGill University; University of Toronto; Laval University; Simon Fraser University

Recruiting

Comprehensive Analysis Platform To Understand, Remedy and Eliminate ALS (CAPTURE ALS)

Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Frontotemporal Degeneration | Progressive Muscular Atrophy

Canada
Eye Hospital Pristina Kosovo

Enrolling by invitation

Human Fresh Corneal Lenticule Implantation Criteria in Progressive Corneal Disease Using Relex-Smile (Relex-Smile)

Progressive Disease of Corneae

Kosovo
McMaster University

Active, not recruiting

Dynamic Proteomics and Integrated Rates of Muscle Protein Synthesis During an Acute Period of Loading and Unloading (HYPAT)

Hypertrophy | Exercise | Proteomics | Atrophy, Disuse

Canada
Duke University
UCB Pharma

Completed

Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease

Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Progressive Muscular Atrophy

United States
University of Miami
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes...

Active, not recruiting

TRIAL READY (Clinical Trial Readiness)

Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Frontotemporal Dementia | Progressive Muscular Atrophy | ALS-Frontotemporal Dementia

United States
University of Alberta

Withdrawn

Digital Smartwatch Measurements as Potential Biomarkers for Remote Disease Tracking in ALS

Healthy | Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Frontotemporal Dementia | Muscular Atrophy, Progressive

Canada
Avidity Biosciences, Inc.

Recruiting

Phase 1/2 Study of AOC 1020 in Adults With Facioscapulohumeral Muscular Dystrophy (FSHD) (FORTITUDE)

Muscular Dystrophies | Muscular Dystrophy, Facioscapulohumeral | FSHD | Facio-Scapulo-Humeral Dystrophy | FMD | Facioscapulohumeral Muscular Dystrophy 1 | FSHD2 | FSHD1 | FMD2 | Fascioscapulohumeral Muscular Dystrophy | Fascioscapulohumeral Muscular Dystrophy Type 1 | Fascioscapulohumeral Muscular Dystrophy... and other conditions

United States, United Kingdom, Canada
Maastricht University Medical Center

Terminated

Neuromuscular Electrical Stimulation During Immobilization Due to Ankle Fractures (ANKL-ES)

Immobilization | Muscle Disuse Atrophy

Netherlands
University of Miami
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes... and other collaborators

Recruiting

Clinical Procedures to Support Research in ALS (CAPTURE-ALS)

Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Progressive Muscular Atrophy | ALS-Frontotemporal Dementia

United States
Columbia University
Muscular Dystrophy Association; Stevens Institute of Technology

Completed

Wearable Technology to Assess Gait Function in SMA and DMD

Duchenne Muscular Dystrophy | Spinal Muscular Atrophy Type 3

United States
Maastricht University Medical Center

Completed

Immobilization and Protein Supplementation (IM-PRO) (IM-PRO)

Aging | Disuse Atrophy

Netherlands
Gillette Children's Specialty Healthcare
University of Minnesota

Completed

Effects of Standing on Non-Ambulatory Children With Spinal Muscular Atrophy

Spinal Muscular Dystrophy | Neuromuscular Disability

United States
Johns Hopkins University
Massachusetts General Hospital; Washington University School of Medicine; Emory... and other collaborators

Completed

Answer ALS: Individualized Initiative for ALS Discovery (AnswerALS)

Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Progressive Muscular Atrophy | Healthy Controls | Flail Arm ALS | Monomelic Amyotrophy | Asymptomatic ALS Gene Carriers

United States
Bispebjerg Hospital

Recruiting

The Impact of Bed Rest, Aging and NMES on Skeletal Muscle

Muscle Function | Neuromuscular Electrical Stimulation | Disuse Atrophy (Muscle) of Lower Extremities | Myofibrillar Protein Synthesis

Denmark
University College, London
University of Oxford; Newcastle University; University of Cambridge; University... and other collaborators

Recruiting

PROgressive Supranuclear Palsy CorTico-Basal Syndrome Multiple System Atrophy Longitudinal Study UK (PROSPECT-M)

Corticobasal Degeneration | Multiple System Atrophy (MSA) | Progressive Supranuclear Palsy (PSP)

United Kingdom
Rigshospitalet, Denmark

Completed

Fat and Glucose Metabolism in Fed and Fasted State in Patients With Low Skeletal Muscle Mass

Spinal Muscular Atrophy | Merosin Deficient Congenital Muscular Dystrophy

Denmark
University College, London
University of North Carolina, Chapel Hill; NYU Grossman School of Medicine

Recruiting

Dentatorubral-pallidoluysian Atrophy Natural History and Biomarkers Study (DRPLA NHBS)

Dentatorubral-Pallidoluysian Atrophy

United States, United Kingdom
Bahçeşehir University

Not yet recruiting

Public AttitudesTowards SMA and DMD Awareness, Newborn and Carrier Screening and Physiotherapy Practices

Duchenne Muscular Dystrophy | Spinal Muscular Atrophy | Healthy Individuals
Maastricht University Medical Center

Completed

Electrical Stimulation During Immobilization (ESDIM)

Immobilization | Neuromuscular Electrical Stimulation | Disuse Atrophy

Netherlands
Nemours Children's Clinic

Completed

WREX Outcome Study

Muscular Dystrophy | Spinal Muscular Atrophy | Arthrogryposis
Merve Kurt

Recruiting

Feasibility of Virtual Reality in Children With Neuromuscular Disease, Effectiveness of Virtual Reality and Biofeedback

Duchenne Muscular Dystrophy | Virtual Reality | Spinal Muscular Atrophy | Neuromuscular Disease | Biofeedback

Turkey
Medical University of Vienna
University of Zurich; Centre Hospitalier Universitaire Dijon; Fundacion Clinic... and other collaborators

Not yet recruiting

Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression (APENNINES)

Age-Related Macular Degeneration | Geographic Atrophy
Assiut University

Not yet recruiting

The Efficacy of Combination Therapy in Atrophic Scars

Atrophic Scar
CellinCells

Recruiting

Safety and Tolerability of Autologous Adipose-derived Mesenchymal Stem Cells Therapy in Adults With Atrophic Scars

Atrophic Scar

Korea, Republic of
Cairo University

Active, not recruiting

Assessment of Bone Quality and Quantity for Three Dimensional Bone Augmentation for Maxilla Using Patient Specific Titanium Meshes Loaded With Bone Marrow Aspirate Mixed With Xenograft Versus Xenograft Mixed With Autografts Only: a Randomized Clinical Trial

Atrophic Maxilla

Egypt
Bio-Medical Research, Ltd.
Liverpool University Hospitals NHS Foundation Trust

Completed

Effects of Kneehab 12-week Peri-operative Total Knee Arthroplasty (KneehabTKA)

Knee Osteoarthritis | Disuse Atrophy

United Kingdom

Clinical Trials on Muscular Atrophy, Progressive

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