Clinical Trials on Myelogenous Leukemia, Chronic

Total 37190 results

Assiut University

Not yet recruiting

Metabolic Alternation and Clinicohematological Characteristic in Chronic Phase CML in Patient Treated With TKI

CML, Chronic Phase
Actinium Pharmaceuticals

Active, not recruiting

Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia (SIERRA)

Acute Myeloid Leukemia | Leukemia, Myeloid, Acute | AML | Acute Myelogenous Leukemia | Bone Marrow Transplant | Myelogenous Leukemia, Acute | Myeloid Leukemia, Acute | Leukemia, Acute Myelogenous | Leukemia, Acute Myeloid

United States, Canada
Il-Yang Pharm. Co., Ltd.

Recruiting

A Phase 3 Study for the Efficacy and Safety of Radotinib in CP-CML Patients With Failure or Intolerance to Previous TKIs

Chronic Myeloid Leukemia, Chronic Phase | CML, Chronic Phase | CML, Refractory | CML - Philadelphia Chromosome

Turkey, Korea, Republic of, Russian Federation, Ukraine
Peking University People's Hospital
Henan Cancer Hospital; Wuhan Union Hospital, China; Zhejiang University; Peking... and other collaborators

Not yet recruiting

The Efficacy and Safety of Third-generation TKIs Combined With Azacitidine and Bcl-2 Inhibitor in Patients With CML-MBP

Chronic Myeloid Leukemia

China
Hikma Pharmaceuticals LLC

Completed

Effectiveness and Safety Study of Generic Imatinib in Chronic Myeloid Leukemia Patients in Egypt

Philadelphia Chromosome-positive Chronic Myeloid Leukemia in Chronic Phase

Egypt
Celgene

Approved for marketing

Expanded Access for CC-486

Acute Myelogenous Leukemia (AML)

United States
University of Michigan Rogel Cancer Center
AstraZeneca

Terminated

Pharmacists Coordinated Care Oncology Model (PCOM) for Patients Taking Oral Anti-cancer Medications

Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Multiple Chronic Conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer

Juvenile Myelomonocytic Leukemia | Chronic Lymphocytic Leukemia | Secondary Acute Myeloid Leukemia | Childhood Acute Lymphoblastic Leukemia | Prolymphocytic Leukemia | Hairy Cell Leukemia | Acute Undifferentiated Leukemia | Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative | Childhood Acute Myeloid... and other conditions

United States, Canada, Australia, New Zealand, Puerto Rico, Switzerland
Masonic Cancer Center, University of Minnesota

Terminated

Adoptive TReg Cell for Suppression of aGVHD After UCB HSCT for Heme Malignancies

Follicular Lymphoma | Myelodysplastic Syndromes | Multiple Myeloma | Hodgkin Lymphoma | Burkitt Lymphoma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Acute Myelogenous Leukemia | Mantle-Cell Lymphoma | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Small... and other conditions

United States
Center for International Blood and Marrow Transplant...
National Marrow Donor Program

Completed

HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide

Chronic Lymphocytic Leukemia (CLL) | Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML) | Chemotherapy-sensitive Lymphoma | Acute Lymphoblastic Leukemia (ALL)/T Lymphoblastic Lymphoma | Acute Biphenotypic Leukemia (ABL) | Acute Undifferentiated Leukemia (AUL)

United States
Center for International Blood and Marrow Transplant...
National Marrow Donor Program; St. Baldrick's Foundation

Recruiting

Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and Young Adults With Relapsed/Refractory Acute Myeloid Leukemia

Acute Myelogenous Leukemia

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Active, not recruiting

Administration of Donor T Cells With the Caspase-9 Suicide Gene (DOTTI)

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Non Hodgkin Lymphoma | Myelodysplastic Syndrome | Chronic Myelogenous Leukemia | Hemophagocytic Lymphohistiocytosis | Epstein Barr Virus Infection | X-linked Lymphoproliferative Disease | Hemophagocytic Syndrome | Familial Hemophagocytic Lymphohistiocytosis

United States
Grupo Espanol de trasplantes hematopoyeticos y...

Completed

Study With Intravenous Busulfan And Fludarabine Myeloablative Conditioning Regimen For HLA Identical Sibling Donor HSCT (BUFLU)

Acute Myeloid Leukemia | Myeloproliferative Disorders | Chronic Myeloid Leukemia | Myelodysplastic Syndrome
Omar Aljitawi

Recruiting

Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myelofibrosis | Chronic Myelomonocytic Leukemia | Myelodysplastic/Myeloproliferative Neoplasm | Atypical Chronic Myeloid Leukemia | Chronic Monocytic Leukemia

United States
King Faisal Specialist Hospital & Research Center

Completed

An Open-Label, Multicenter, Expanded Access Study of Oral AMN 107 in Adult Patients With Imatinib (Glivec®/Gleevec®_ - Resistant or Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase

Leukemia, Myeloid, Chronic
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphoma

Acute Myeloid Leukemia | Hodgkin Lymphoma | Recurrent Hodgkin Lymphoma | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Refractory Myelodysplastic Syndrome and other conditions

United States
University of California, San Francisco

Completed

Phase II Study Evaluating Busulfan and Fludarabine as Preparative Therapy in Adults With Hematopoietic Disorders Undergoing MUD SCT

Multiple Myeloma | Non-Hodgkin's Lymphoma | Chronic Myeloid Leukemia | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Myelodysplasia | Severe Aplastic Anemia | Lymphoproliferative Disease | Advanced Myeloproliferative Disease

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Pentostatin and Lymphocyte Infusion in Preventing Graft Rejection in Patients Who Have Undergone Donor Stem Cell Transplant

Acute Myeloid Leukemia | Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Plasma Cell Myeloma | Myelodysplastic/Myeloproliferative Neoplasm | Graft Versus Host Disease | Chronic Myelogenous Leukemia, BCR-ABL1 Positive

United States, Italy
Children's Hospital Medical Center, Cincinnati

Recruiting

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

Lymphoma | Follicular Lymphoma | Leukemia | B Cell Lymphoma | Hodgkin Lymphoma | Burkitt Lymphoma | AML | Non Hodgkin Lymphoma | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Diffuse Large B Cell Lymphoma | Hematologic Malignancy | Chronic Myelogenous Leukemia | Myeloproliferative Neoplasm | T-cell Lymphoma | Peripheral T Cell Lymphoma and other conditions

United States
Facet Biotech
National Cancer Institute (NCI)

Unknown

Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia

Leukemia

United States, Canada, Netherlands, Belgium, Germany, United Kingdom, France
European Society for Blood and Marrow Transplantation
Amgen

Withdrawn

Palifermin After Haploidentical PBSCT (KGF Haplo Allo)

Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Acute Leukaemia | Non-Hodgkin's Lymphoma or Hodgkin's Disease | Osteomyelofibrosis

Germany
Ohio State University Comprehensive Cancer Center

Active, not recruiting

Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS Study

Hematopoietic and Lymphoid Cell Neoplasm | Acute Myeloid Leukemia | Hodgkin Lymphoma | Myelofibrosis | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Plasma Cell Myeloma | Aplastic Anemia | Myeloproliferative Neoplasm | Chronic Myelogenous Leukemia...

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders

Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasms | Atypical Chronic Myeloid Leukemia | Myelodysplastic/Myeloproliferative Overlapping Syndrome

United States
University of Connecticut

Completed

Study Using Vaccination With Heat Shock Protein 70 (HSP70) for the Treatment of CML in Chronic Phase

Leukemia,Myeloid, Chronic | Leukemia,Myeloid,Philadelphia-Positive

United States
Asan Medical Center

Terminated

Randomized Study of Haploidentical Hct and Subsequent Donor nk Cell Infusion in High-risk AML and MDS (DNKI-4)

Acute Myelogenous Leukemia

Korea, Republic of
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Unknown

Monoclonal Antibody in Treating Patients With Acute Myelogenous Leukemia

Leukemia

United States
Poitiers University Hospital

Active, not recruiting

Innate T Cells and TKI Discontinuation (TIBIOP-LMC)

Chronic Myeloid Leukemia

France
Diane George

Recruiting

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML) | Chronic Myeloid Leukemia (CML) | Juvenile Myelomonocytic Leukemia (JMML) | Lymphoma (Hodgkin's and Non-Hodgkin's)

United States
Therapeutic Advances in Childhood Leukemia Consortium

Completed

Epigenetic Reprogramming in Relapse/Refractory AML

Acute Myelogenous Leukemia

United States, Canada, Australia
M.D. Anderson Cancer Center

Recruiting

Off-the-shelf NK Cells + SCT for Myeloid Malignancies

Acute Myeloid Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Myeloid Malignancies

United States
Rambam Health Care Campus
Miltenyi Biomedicine GmbH

Unknown

Allogeneic Stem Cell Transplantation in CML With Partial T Cell Depletion

Philadelphia Chromosome-positive Chronic Myelocytic Leukemia

Israel
The Korean Society of Blood and Marrow Transplantation
Chonbuk National University Hospital; Samsung Medical Center; Seoul St. Mary's... and other collaborators

Terminated

Sirolimus/Tacrolimus Combination After HLA Matched Related Peripheral Blood Stem Cell Transplants

Myelodysplastic Syndromes | Leukemia, Myeloid, Chronic-Phase | Acute Leukemia in Remission | Leukemia, Myeloid, Accelerated-Phase

Korea, Republic of
University of Cincinnati
Novartis

Withdrawn

A Study Evaluating the Effects of CLAG With Gleevec in Refractory or Relapsed Acute Myeloid Leukemia

Acute Myeloid Leukemia | Chronic Myeloid Leukemia, Blast Crisis

United States
Therapeutic Advances in Childhood Leukemia Consortium

Terminated

Phase I Study of GNKG168 in Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia

Relapsed Acute Lymphoblastic Leukemia | Relapsed Acute Myelogenous Leukemia

United States
Sun Pharma Advanced Research Company Limited

Active, not recruiting

Safety and Anti-leukemic Activity of Vodobatinib (K0706) for Treatment of Ph+ CML Resistant/Intolerant to ≥3 Prior CML Therapies

Healthy (For Part A) | Chronic Myeloid Leukemia (for Part B and C)

United States, Spain, Hungary, Italy, India, Belgium, France, Romania, Singapore, United Kingdom, Korea, Republic of, Turkey
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Unknown

NK Cells in Cord Blood Transplantation

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Small Lymphocytic Lymphoma | Refractory Chronic Lymphocytic Leukemia | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Recurrent Acute Lymphoblastic Leukemia and other conditions

United States
Novartis Pharmaceuticals

Active, not recruiting

A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP

Chronic Myeloid Leukemia (CML) Philadelphia Chromosome Positive

United States, China, Hungary, Japan, Belgium, Germany, Canada, Singapore, Australia, Israel, Netherlands, Spain, Italy, Korea, Republic of, Bulgaria, France, United Kingdom, Czechia, Sweden, India, Malaysia, Denmark, Taiwan, Norway, Fi... and more
Massachusetts General Hospital

Completed

Reduced Intensity Double Umbilical Cord Blood Transplantation

Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Chronic Lymphocytic Leukemia | Acute Myelogenous Leukemia

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

Acute Myeloid Leukemia | High Risk Myelodysplastic Syndrome | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Philadelphia Chromosome Positive | Myeloproliferative Neoplasm | Myeloid Sarcoma | Blasts 10 Percent or More of Bone Marrow Nucleated Cells

United States
M.D. Anderson Cancer Center
Ascentage Pharma Group Inc.

Not yet recruiting

A Phase I Study of Decitabine, Lisaftoclax, and Olverembatinib in Patients With Advanced Chronic Myeloid Leukemia and Philadelphia Chromosome-Positive Acute Myeloid Leukemia

Advanced Chronic Myeloid Leukemia | Philadelphia Chromosome-Positive Acute Myeloid Leukemia

United States
Imperial College Healthcare NHS Trust

Active, not recruiting

The Analysis of Fatigue on Tyrosine Kinase Inhibitor Therapy in Chronic Myeloid Leukaemia (TIRE)

Fatigue | Sleep Disturbance | Chronic Myeloid Leukemia | Chronic Myeloid Leukemia, Chronic Phase

United Kingdom
Novartis Pharmaceuticals

Terminated

Efficacy and Safety of LBH589B in Adult Patients With Refractory Chronic Myeloid Leukemia in Accelerated or Blast Phase

Leukemia, Myeloid, Chronic

United States, Germany
Bristol-Myers Squibb

Completed

Dasatinib (BMS-354825) in Subjects With Myeloid Blast Phase Chronic Myeloid Leukemia Resistant to or Intolerant of Imatinib Mesylate

Chronic Myeloid Leukemia | Blast Crisis

Netherlands, United States, Italy, Austria, Canada, France, Germany, Singapore, Taiwan, United Kingdom, Australia, Korea, Republic of, Philippines, Sweden, Finland, Israel, Belgium, Denmark, Norway, Switzerland
Scripps Health

Completed

Nonmyeloablative Allogeneic Transplant (Mini-allo)

Melanoma | Sarcoma | Renal Cell Carcinoma | Breast Cancer | Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Ovarian Cancer | Thymoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia and other conditions

United States
Shenzhen Second People's Hospital

Recruiting

TKI Discontinuation in CML Patients of China (TFR_china)

Leukemia | Myelogenous | Chronic | BCR-ABL (Breakpoint Cluster Region-abelson Murine Leukemia) | Positive

China
H. Lee Moffitt Cancer Center and Research Institute

Active, not recruiting

Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Hodgkin Lymphoma | Burkitt Lymphoma | Acute Lymphoblastic Leukemia | Mantle Cell Lymphoma | Lymphoplasmacytic Lymphoma | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Myeloproliferative Neoplasm | Relapsed Follicular Lymphoma | Relapsed T-Cell Lymphoma and other conditions

United States
Sheba Medical Center

Unknown

Imatinib Versus Imatinib and Peg-Interferon in Patients With Ph+ CML and Complete Cytogenetic Response After Imatinib Therapy

Leukemia, Myeloid, Philadelphia-Positive

Israel
National Taiwan University Hospital

Recruiting

Therapeutic Drug Monitoring of Tyrosine Kinase Inhibitor in Patients With Chronic Myeloid Leukemia

Pharmacokinetics | Therapeutic Drug Monitoring | Tyrosine Kinase Inhibitor

Taiwan
Masonic Cancer Center, University of Minnesota

Completed

Relapse Prophylaxis With N-803 for AML and MDS Pts Following Allo HSCT

Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML)

United States
St. Petersburg State Pavlov Medical University

Terminated

Trial of GVHD Prophylasxis With PTCy or Thymoglobulin in Unrelated SCT

Myelodysplastic Syndromes | Leukemia, Chronic Myeloid | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

Russian Federation

Clinical Trials on Myelogenous Leukemia, Chronic

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