Clinical Trials on NPM1 Mutation

Total 1649 results

University Medical Center Groningen
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Economic Evaluation of Lower Limb Prostheses for Persons With a Knee-disarticulation or Transfemoral Amputation

Amputation | Prosthesis | Prosthesis User

Netherlands
Orthocare Innovations, LLC
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Assist-Knee: Energy-Harvesting Knee Prosthesis

Artificial Limbs | Transfemoral Amputation

United States
Institute for Clinical Evaluative Sciences
Canadian Institutes of Health Research (CIHR); Ontario Agency for Health Protection... and other collaborators

Completed

Feedback to Improve Rational Strategies of Antibiotic Initiation and Duration in Long Term Care (FIRST AID -LTC) - Phase 2 (FIRST AID-LTC)

Antibiotic Initiation | Antibiotic Duration

Canada
Hacettepe University

Unknown

Comparison of Dual Task Gait Characteristics in Individuals With Amputation and Healty Individuals

Amputation | Gait | Dual Task

Turkey
Loma Linda University

Completed

Effect of a Novel Stretching Technique on Shoulder Range of Motion and Voluntary Contraction in Overhead Athletes With Glenohumeral Internal Rotation Deficits "GIRD" (GIRD)

Glenohumeral Internal Rotation Deficits

United States
Sheba Medical Center

Withdrawn

The Influence of Education of Medical Team on Duration of Fasting Before Elective Medical Interventions Performed Under General Anesthesia in Children

Duration of Preoperative Fasting

Israel
Tel-Aviv Sourasky Medical Center
United States Department of Defense

Recruiting

Evaluation of the Frequency and Severity of Sleep Abnormalities in Patients With Parkinson's Disease

Parkinson Disease | GBA Gene Mutation | Leucine-rich Repeat Kinase 2 (LRRK2) Gene Mutation

Israel
GlaxoSmithKline

Withdrawn

Efficacy and Safety Study of GSK1120212, a MEK Inhibitor, in Subjects With Uveal Melanoma

Cancer | Metastatic Uveal Melanoma | GNA11 Mutation-positive Metastatic Melanoma | GNAQ Mutation-positive Metastatic Melanoma
ETH Zurich

Recruiting

Enhancing Abilities in Amputees and Patients With Peripheral Neuropathy Through Restoration of Sensory Feedback

Lower Limb Amputation Below Knee (Injury) | Lower Limb Amputation Above Knee (Injury) | Diabetic Peripheral Neuropathy | Lower Limb Amputation Knee

Switzerland
Phantom Neuro Inc.

Not yet recruiting

Assessment of Gesture Accuracy of a Prosthesis Control System (ASCENT)

Upper Limb Amputation Below Elbow (Injury)
Azienda Ospedaliero, Universitaria Pisana
Scuola Superiore Sant'Anna di Pisa

Recruiting

A Bidirectional MyoKinetic Implanted Interface for Natural Control of Artificial Limbs (MYKY)

Upper Limb Amputation at the Wrist

Italy
Federal University of Espirito Santo

Enrolling by invitation

Identify the Prosthesis Users' Necessities Concerning Their Devices.

Upper Limb Amputation at the Hand

Brazil
University Hospital, Basel, Switzerland

Completed

Clitoral Reconstruction (CR) in FGM/C Patients

Female Genital Mutilation / Cutting (FGM/C)

Switzerland
Vrije Universiteit Brussel

Completed

Comprehensive Evaluation of the Passive Talaris Demonstrator

Lower Limb Amputation Below Knee (Injury)

Belgium
Osijek University Hospital

Completed

Ultrasound of Accessory Respiratory Muscles

Mechanical Ventilation | Survival | Duration of Treatment

Croatia
Sint Maartenskliniek

Completed

The Effects of Small Variations in Shoe Heel Height on Gait in People With a Transtibial Amputation

Lower Limb Amputation Below Knee (Injury)
Medical University of Vienna

Unknown

Rotational Stability of a Hydrophobic Acrylic Plate Haptic Intraocular Lens Using a Capsular Tension Ring - An Intraindividual Comparative Study (ConTRol)

Intraocular Lens Rotation | Capsular Tension Ring

Austria
Mayo Clinic
American Orthotic and Prosthetic Association

Completed

Comparative Effectiveness Between Microprocessor Knees and Non-Microprocessor Knees (MPK-AOPA)

Lower Limb Amputation Above Knee (Injury)

United States
University Hospital, Grenoble
TIMC-IMAG

Completed

Analyzing Stump-socket Interface Pressure to Improve Gait in Above-knee Amputee

Lower Limb Amputation Above Knee (Injury)

France
University of Virginia

Not yet recruiting

Genetic Information Assistant in Telegenetics

Genetic Predisposition | Gene Mutation-Related Cancer
Institut Curie

Recruiting

COsegregation of VARiants in Panel of Genes (COVAR)

Genetic Predisposition | Gene Mutation-Related Cancer

France, Guadeloupe, Martinique, Réunion
Symphogen A/S

Completed

Sym015 (Anti-MET) in Patients With Advanced Solid Tumor Malignancies

NSCLC | Non Small Cell Lung Cancer | Oncology | MET Gene Mutation | MET Gene Amplification

United States, Korea, Republic of, Denmark, Hong Kong, Taiwan, Spain
Li Junmin

Unknown

Decitabine,Cytarabine and Arsenic Trioxide for Acute Myeloid Leukemia With p53 Mutations

Acute Myeloid Leukemia | P53 Mutation

China
Liberating Technologies, Inc.
Vivonics, Inc.

Completed

Moisture Management Liner At-Home Evaluation

Amputation | Prosthesis | Prosthesis User | Amputation Stump | Amputees | Lower Limb Deformity

United States
Tianjin Medical University Cancer Institute and...

Recruiting

Osimertinib Plus Dalpiciclib in Patients With EGFR-mutant, CDK4/6 Pathway Aberrant, Advanced Non-small Cell Lung Cancer Following Acquired Resistance to Third-generation EGFR TKI: a Phase II Trial

Non-small Cell Lung Cancer | EGFR Activating Mutation | EGFR-TKI Resistant Mutation | Cell Cycle Deregulation

China
Pamela Munster
Novartis

Withdrawn

Alpelisib in Combination With Carboplatin in Patients With Solid Tumors and HPV-Positive Squamous Cell Carcinoma

Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Solid Tumors, Adult | HPV-Related Squamous Cell Carcinoma | Human Papillomavirus-Related Carcinoma | PIK3CA Mutation-Related Tumors | PIK3CA Mutation | Human Papillomavirus-Related Squamous Cell Carcinoma

United States
University College, London
Washington University School of Medicine; University of Washington; Alzheimer... and other collaborators

Not yet recruiting

A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK (NIO-SILK)

Alzheimer Disease | Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) | Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 2 (Disorder) | Autosomal Dominant Alzheimer Disease Due to Mutation of Amyloid Precursor Protein (Disorder)
Tanta University

Recruiting

Perineural Methylene Blue Infusion in Lower Limb Amputation Surgery

Lower Limb Amputation | Methylene Blue | Perineural

Egypt
Massachusetts Institute of Technology
Hanger Clinic: Prosthetics & Orthotics

Recruiting

Evaluation of High-Performance, Customized, Rapidly-Manufacturable Prosthetic Feet That Provide Improved Mobility

Amputation of Lower Limb Below Knee

United States
University of Washington

Completed

Auto Control of Volume Management for Limb Loss

Lower Limb Amputation Below Knee (Injury)

United States
Proteor Group

Completed

Above-knee Socket Evaluation : Sub-ischial vs Ischial Containment (P20-EMBSUBI)

Lower Limb Amputation Above Knee (Injury)

France
Vrije Universiteit Brussel

Unknown

Decoding Motion Planning Using Cortical Potentials

Lower Limb Amputation Above Knee (Injury)

Belgium
Southern California Institute for Research and...
Vanderbilt University

Unknown

Kinematic, Kinetic, and Metabolic Comparison of Bilateral Transfemoral Ambulation With Passive Versus Powered Prosthetic Devices

Amputation | Energy Expenditure | Artificial Limbs | Kinetics

United States
University Hospital, Angers

Completed

Comparing New Prothesis PROPRIO-FOOT® Versus Usual Prothesis Tasks Tibial Amputees (PROPRIO-FOOT)

Lower Limb Amputation at Ankle (Injury)

France
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Influence of Socket Volume on Prosthesis Performance (CAD)

Lower Limb Amputation Below Knee (Injury)

United States
Uppsala University
Malmö University

Completed

A Community-based Participatory Intervention to Change Attitudes Towards Female Circumcision Among Somali Immigrants in Sweden

Female Circumcision | Female Genital Mutilation/Cutting

Sweden
Azienda Ospedaliera San Gerardo di Monza

Completed

Evaluation of a Closed Suction System to Remove Secretions From the Endotracheal Tube

Intubation | Expected Duration of Ventilation > 48h

Italy
University Health Network, Toronto

Completed

Effect of Remifentanil Boluses on Hemodynamics in Skull Pin Insertion

Skull Pin Insertion | Short Duration Analgesia

Canada
Hutchmed

Recruiting

A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

Isocitrate Dehydrogenase Gene Mutation

Spain, United States
Centre Hospitalier Universitaire, Amiens

Completed

C677T Methylenetetrahydrofolate Reductase Mutation (C677T)

Mutation
The First Affiliated Hospital of Soochow University

Recruiting

Avapritinib in CBF-AML With KIT Mutations

Core Binding Factor Acute Myeloid Leukemia | KIT Mutation-Related Tumors

China
Bayer

Recruiting

A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United Kingdom
Bayer

Active, not recruiting

A Study to Learn About How BAY2927088 Affects the Level of Midazolam in the Blood When Both Drugs Are Taken Together in Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United States
Bayer

Completed

A Study to Learn How BAY2927088 is Taken up and Handled by the Body in Healthy Male Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

Netherlands
Instituto Nacional de Cancerologia de Mexico

Unknown

Metformin Plus TKI Use in Patients With Non-Small Cell Lung Carcinoma

EGFR Gene Mutation | Tyrosine Kinase Mutation | Non-Small Cell Adenocarcinoma

Mexico
Second Xiangya Hospital of Central South University
The First Affiliated Hospital of Nanchang University; Xiangya Hospital of Central... and other collaborators

Recruiting

Exploring the Mechanism of Primary Resistance to Third-generation EGFR-TKIs as First-line Treatment in EGFR-positive Advanced NSCLC (PRECISE Study) (PRECISE)

Lung Cancer, Non-small Cell | Circulating Tumor DNA | EGFR Gene Mutation | EGFR-TKI Resistant Mutation | Primary Resistance

China
Sameek Roychowdhury
National Cancer Institute (NCI)

Withdrawn

Brigatinib in Treating Patients With ALK and ROS1 Gene Alterations and Locally Advanced or Metastatic Solid Cancers

Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | ALK Gene Mutation | Metastatic Malignant Neoplasm in the Brain | Advanced Malignant Neoplasm | ALK Fusion Protein Expression | Metastatic Malignant Neoplasm in the Central Nervous System | ROS1 Gene Mutation | ALK Gene... and other conditions

United States
Women's College Hospital
Canadian Institutes of Health Research (CIHR); London Health Sciences Centre; H. Lee Moffitt Cancer Center and Research Institute and other collaborators

Unknown

Cancer Prevention in Women With a BRCA Mutation

Breast Cancer | Ovarian Cancer | BRCA1 Gene Mutation | BRCA2 Gene Mutation

Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Epacadostat and Pembrolizumab in Treating Participants With Advanced Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Homologous Recombination Deficiency | Stage IIA Pancreatic Cancer AJCC v8 | Stage IIB Pancreatic Cancer AJCC v8 | ATM Gene Mutation | Deleterious BRCA1 Gene... and other conditions
Orum Therapeutics USA, Inc.

Recruiting

Study of ORM-5029 in Subjects With HER2-Expressing Advanced Solid Tumors

HER2-positive Breast Cancer | HER-2 Gene Amplification | HER2 Gene Mutation | HER-2 Protein Overexpression

United States

Clinical Trials on NPM1 Mutation

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CROs in South Korea

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