Clinical Trials on NRG1 Fusion

Total 2356 results

Merus N.V.

Recruiting

A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy)

NSCLC Harboring NRG1 Fusion | Solid Tumours Harboring NRG1 Fusion | Pancreatic Cancer Harboring NRG1 Fusion | NRG1 Fusion

Spain, France, Israel, Belgium, Denmark, United States, Korea, Republic of, Japan, Germany, Netherlands, Austria, Canada, Italy, Norway, Singapore, Sweden, Taiwan, United Kingdom
Pacira Pharmaceuticals, Inc

Completed

Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPAREL Admixed With Bupivacaine HCl vs. Bupivacaine HCl Administered as Combined Sciatic and Saphenous Nerve Blocks for Postsurgical Analgesia in Subjects Undergoing Lower Extremity Surgeries (STRIDE)

Bunion | Midfoot Fusion | Total Ankle Arthroplasty | Lower Extremity Surgery | Metatarsophalangeal Fushion | Hindfoot Fushion

United States
Merus N.V.

Recruiting

Study Evaluating Zenocutuzumab in Patients With or Without Molecularly Defined Cancers

Metastatic Castration-resistant Prostate Cancer | NSCLC Harboring NRG1 Fusion

United States
German Cancer Research Center
German Consortium for Translational Cancer Research

Completed

Afatinib in Advanced NRG1-Rearranged Malignancies

Metastatic and Locally Advanced NRG1-rearranged Malignancies

Germany
Pacira Pharmaceuticals, Inc

Withdrawn

Phase 3, Randomized, Double Blinded, Active Controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL Admixed With Bupi vs. Bupi Only Administered as Combined Sciatic and Adductor Canal Nerve Block for Postsurgical Analgesia in Lower Extremity Surgeries (STRIDE)

Bunion | Metatarsophalangeal Fusion | Midfoot Fusion | Hindfoot Fusion | Total Ankle Arthroplasty | Forefoot Surgery
Rain Oncology Inc

Terminated

Study of Tarloxotinib in Pts With NSCLC (EGFR Exon 20 Insertion, HER2-activating Mutations) & Other Solid Tumors With NRG1/ERBB Gene Fusions (RAIN)

NSCLC Stage IIIB | NSCLC, Recurrent | NRG1 Fusion | EGFR Exon 20 Insertion Mutation | NSCLC, Stage IIIC | NSCLC, Stage IV | HER2-activating Mutation | ERBB Fusion

United States, Canada, Hong Kong
Duke University

Completed

Impact of Body Habitus (Arm Span and Abdominal Girth) on Activities of Daily Living (ADL) (ADL)

Spinal Fusion | Activities of Daily Living Following Complex Spinal Fusions

United States
Massachusetts Eye and Ear Infirmary
National Eye Institute (NEI)

Completed

Understanding Visual Confusion Using Stereoscopic Displays

Diplopia | Binocular Vision Suppression | Binocular; Fusion, With Defective Stereopsis | Monocular Diplopia

United States
National Taiwan University Hospital

Terminated

Clinical and Biomechanics Research in Core Muscles After Lumbar Fusion Surgery

Lumbar Fusion | Lumbar Spinal Fusion Surgery

Taiwan
Sewon Cellontech Co., Ltd.

Unknown

Efficacy and Safety of SurgiFill™ on Spinal Fusion

Spinal Fusion Acquired | Fusion of Spine (Disease)

Korea, Republic of
Xtant Medical
RTI Surgical

Recruiting

Prospective SPINE Registry (SPINE)

Joint Diseases | Musculoskeletal Diseases | Spinal Stenosis | Fusion of Spine | Spine | Spinal Fusion | Spinal Disease | Spinal Instability | Sacroiliac; Fusion | Fusion of Joint | Sacroiliac

United States, Spain, Germany
Centre Leon Berard

Recruiting

Real Word European Registry of NTRK Fusions and Other Rare Actionable Fusions (TRacKING) (TRacKING)

Cancer | Cancer Metastatic | ALK Fusion Protein Expression | FGFR2 Gene Translocation | FGFR3 Gene Translocation | NTRK Family Gene Mutation | Gene Fusion | ROS1 Gene Translocation | NTRK Gene Fusion Overexpression | ATIC-ALK Fusion Protein Expression | BCR-FGFR1 Fusion Protein Expression | COL1A1-PDGFB Fusion... and other conditions

France, Denmark, Netherlands, Austria, Germany, Italy, United Kingdom, Czechia, Poland, Slovenia, Spain
AXIS Spine Center- a division of Northwest Specialty...
IDAHO PANHANDLE HEALTH DISTRICT

Recruiting

Pre-Operative Ketamine Infusion for Post Operative Pain Control After Revision Spinal Surgery (KIPSs)

Cervical Fusion | Fusion of Spine | Lumbar Fusion | Revision Spine Surgery

United States
Oregon Health and Science University

Not yet recruiting

Steroids After Spine Fusion Surgery

Spine Fusion

United States
Chi Mei Medical Hospital

Active, not recruiting

Evaluation of Treatment Effect of Minimally Invasive Spinal Fusion Surgery

Spinal Fusion
Exela Pharma Sciences, LLC.

Terminated

Efficacy and Safety of Tranexamic Acid in Spinal Fusion Surgery

Spinal Fusion

United States
Gia Dinh People Hospital

Completed

The Efficacy of Postoperative Analgesia of Gabapentin Plus Nefopam in the Spinal Surgery

Spinal Fusion

Vietnam
Mayo Clinic

Completed

Thromboelastography-Guided Fluid Management in Spinal Surgery

Spinal Fusion

United States
George Papanicolaou Hospital

Completed

SSEP Fluctuations Due to Dexmedetomidine During Posterior Spine Fusion

Spinal Fusion
BioAlpha Inc.

Unknown

The Clinical Study of Novosis in Posterolateral Fusion

Posterolateral Fusion

Korea, Republic of
OrthoGeorgia
Baxter Healthcare Corporation

Unknown

A Retrospective Study of Actifuse Synthetic Bone Graft Versus Other Bone Graft Substitutes in Patients Requiring Lumbar Fusion

Lumbar Fusion

United States
AO Foundation, AO Spine

Not yet recruiting

Durability of Suppl. Rod Constructs-SuppleMentAry Rod Technique for Long-segment Posterior Instrumented Spinal Fusions

Spinal Fusion

United States
M.C. Kruyt, MD, PhD
Kuros BioSciences B.V.

Active, not recruiting

MagnetOs™ Granules vs. Autograft in Instrumented Posterolateral Spinal Fusion (MaxA)

Spinal Fusion

Netherlands
Augmedics

Completed

Pedicle Screw Placement With XVS

Spine Fusion

Israel
Sunnybrook Health Sciences Centre
Medtronic Sofamor Danek

Completed

A Study on the Use of a Brace Following Low Back Surgery

Lumbar Fusion

United States
Montefiore Medical Center

Terminated

Evaluating the Role of Pregabalin in Reducing Opioid Requirement in Spinal Fusion Surgeries of Two or More Vertebrae

Spinal Fusion

United States
University of Washington
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Understanding Non-Response in Spine Fusion Surgery

Spine Fusion

United States
Taipei Veterans General Hospital, Taiwan

Completed

Risk Factors of Second Surgery for Adjacent Segment Disease Following Anterior Cervical Discectomy and Fusion (2nd ACDF)

Spinal Fusion

Taiwan
Assiut University

Unknown

Minimally Invasive Versus Open Transforaminal Lumbar Interbody Fusion

Spinal Fusion
Hadassah Medical Organization

Unknown

GO-LIF With Percutaneous Facet Fusion

Lumbar Fusion

Israel
Children's Hospital of Philadelphia
Children's Anesthesiology Associates, Ltd.

Completed

Remifentanil Propofol Infusion in Pediatric Spinal Surgery

Spinal Fusion

United States
Istituto Ortopedico Rizzoli

Recruiting

Endothelial Damage in Major Spine Surgery, Measured by Circulating Syndecan-1: an Observational Study.(GlycOrtho) (GlycOrtho)

Spinal Fusion

Italy
Ohio State University
Medtronic

Recruiting

Clinical and Radiological Outcomes of Posterior Cervical Fusion Supplemented With Interfacet Spacers

Cervical Fusion

United States
NYU Langone Health

Active, not recruiting

BMAC & Allograft vs BMP-2

Spinal Fusion

United States
Istituto Ortopedico Rizzoli

Completed

Bone Marrow Clot for Posterior Lumbar Fusion

Spinal Fusion

Italy
SeaSpine, Inc.

Active, not recruiting

Anterior Gen Plus Study

Spine Fusion

United States
Aesculap AG

Completed

Clinical and Radiological Investigation of a New Spinal Fixateur Interne (Ennovate®) (TENNIS)

Spinal Fusion

Germany
Hospital for Special Surgery, New York

Terminated

The Effects of Dexmedetomidine Dose on Motor Evoked Potentials

Spinal Fusion

United States
NYU Langone Health

Completed

A Comparison of Ketamine Infusion Versus Placebo in Opioid Tolerant and Opioid Naive Patients After Spinal Fusion

Spinal Fusion

United States
Mohammad ARAB MOTLAGH

Completed

Transforaminal Lumbar Interbody Fusion in PEEK Oblique Cages With and Without Titanium Coating

Vertebral Fusion
Medtronic Spinal and Biologics

Completed

InductOs® in Real World Spine Surgery; A Retrospective, French, Multi-centric, Study (InductOR)

Spine Fusion

France
China Medical University Hospital

Not yet recruiting

Navigation Image Accuracy Test in Cervical Spine Surgery Using Anatase Spine Surgery Navigation System

Cervical Spine Fusion
Senthil Sadhasivam
National Institute on Drug Abuse (NIDA)

Recruiting

Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB) (PPAP Spine)

Spine Fusion | PPAP

United States
Gangnam Severance Hospital

Completed

Comparison of Postoperative QoR-15 Scores Between Desflurane and Remimazolam in Lumbar Fusion Surgery

Lumbar Fusion Surgery

Korea, Republic of
Joseph D. Tobias

Completed

Changes in Cerebral Oxygenation Based on Intraoperative Ventilation Strategy

Posterior Spinal Fusion

United States
Clinique Saint Jean, France

Recruiting

Erector Spinae Plane Block in Lumbar Spinal Fusion (MERFUSION)

Lumbar Spinal Fusion

France
Thomas Jefferson University
Ethicon, Inc.

Completed

Comparative Analysis of Sutures for Fascial Closure in Spinal Surgery

Fusion of Spine

United States
Assiut University

Completed

Sagittal Parameters After Mono Segmental Lumber Fusion: Interbody Versus Postrolateral Fusion

Lumbar Spine Fusion

Egypt
Assiut University

Not yet recruiting

Single Level Anterior Cervical Corpectomy Without Posterior Stabilization

Cervical Spine Fusion
University Hospital, Basel, Switzerland

Completed

Retrospective Analysis of the Effects of Perioperative Osteoanabolic Treatment on Patients With Spinal (Fusion) Surgery.

Spinal (Fusion) Surgery

Switzerland

Clinical Trials on NRG1 Fusion

Sponsors and Collaborators

Medical Conditions

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CROs in Russia

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Rare Diseases

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