Clinical Trials on Negative Consequences of Alcohol Use in Canada

Total 61 results

Women's College Hospital

Recruiting

Screening While You Wait 2: Alcohol and Tobacco Use (SWYW2)

Alcohol; Harmful Use | Tobacco Use | Tobacco Use Cessation | Alcohol Use, Unspecified

Canada
Zeno Functional Foods, LLC
INQUIS Clinical Research Ltd.

Completed

Effect of Different Foods Together With a Small Dose of Alcohol on Alcohol Levels in Healthy Subjects

Alcohol Use, Unspecified

Canada
Université du Québec à Trois-Rivières

Completed

My Choices: Efficacy and Implementation Study

Alcohol Use, Unspecified | Alcohol Use Disorder, Mild

Canada
Centre for Addiction and Mental Health

Recruiting

Cytisine for Smoking Cessation

Smoking Cessation | Tobacco Use Disorder | Alcohol Use Disorder

Canada
University of Windsor
Centre for Addiction and Mental Health

Recruiting

The Pocket Skills Adjunct Project

Depression | Anxiety | Substance Use Disorders | Alcohol Use Disorder

Canada
University of Manitoba

Completed

Testing the Efficacy of an Online Integrated Treatment for Comorbid Alcohol Misuse and Emotional Problems

Alcohol Use Disorder

Canada
University of Calgary
Johns Hopkins University; University of Maryland; Canadian Institutes of Health...

Recruiting

Psilocybin-Assisted Psychotherapy for Alcohol Use Disorder (PAP-AUD)

Alcoholism | Alcohol Use Disorder

Canada
Centre for Addiction and Mental Health

Completed

Role of BP1.3656 on Alcohol Responses

Alcohol Use Disorder

Canada
Centre for Addiction and Mental Health
University Health Network, Toronto; Maple Leaf Research

Active, not recruiting

PrEP and Alcohol - Enhancing HIV Pre-Exposure Prophylaxis (PrEP)

Hazardous Alcohol Use

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Recruiting

Intensive Virtual Treatment With Remote Abstinence Monitoring for Alcohol Use Disorder

Alcohol Use Disorder

Canada
Dr. Nazanin Alavi

Recruiting

Online Relapse Prevention Therapy for Patients With Alcohol Use Disorder

Alcohol Use Disorder

Canada
Sunnybrook Health Sciences Centre

Active, not recruiting

Deep Brain Stimulation (DBS) for the Treatment of Refractory Alcohol Use Disorder (AUD): Pilot Trial

Alcohol Use Disorder

Canada
Centre for Addiction and Mental Health

Completed

Exploring Regulation and Function of Dopamine D3 Receptors in Alcohol Use Disorders: A [11C]-(+)-PHNO Study

Alcohol Use Disorder

Canada
Centre for Addiction and Mental Health
University of Missouri, St. Louis

Completed

A Dialectical Behavioral Therapy Digital Health Solution for Outpatients Seeking Support for Substance Use

Substance Use Disorders | Alcohol Use Disorder

Canada
Phil Tibbo
Canadian Institutes of Health Research (CIHR)

Recruiting

Piloting of an Intervention to Reduce Problematic Alcohol Use in Early Phase Psychosis Patients

Psychosis | Alcohol Use Disorder

Canada
Centre for Addiction and Mental Health

Recruiting

Cognitive Dysfunction in the Addictions Study - Project 4 (P4) (CDiA-P4)

Major Depressive Disorder | Alcohol Use Disorder

Canada
Clairvoyant Therapeutics
Optimapharm

Recruiting

Psilocybin-Assisted Psychotherapy in Adults With Alcohol Use Disorder (AUD)

Alcohol Use Disorder

Canada, Finland
Centre for Addiction and Mental Health

Recruiting

Testing a Novel Therapeutic Strategy for Comorbid Post-Traumatic Stress Disorder and Alcohol Use Disorder

Stress Disorders, Post-Traumatic | Alcohol Use Disorder

Canada
University of British Columbia

Completed

An Online Intervention Addressing Mental Health and Substance Use in University Students

Depression | Anxiety | Alcohol Use | Substance Use

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR); AFP Innovation Fund

Recruiting

Phenotyping Patients With Alcohol and Cannabis Use Disorders Using the Addictions Neuroclinical Assessment

Alcohol Use Disorder | Cannabis Use Disorder

Canada
McMaster University

Active, not recruiting

Using Neuroeconomics to Characterize State-Based Increases and Decreases in Alcohol Value

Alcohol Drinking | Alcohol Use Disorder

Canada
Centre for Addiction and Mental Health

Completed

Brief Internet Intervention for Hazardous Alcohol Use to People Seeking Online Help for Depression

Depression | Problem Drinking

Canada
University of Regina
Saskatchewan Health Research Foundation; Saskatchewan Centre for Patient-Oriented... and other collaborators

Completed

Internet-delivered Therapy for Alcohol Misuse: Investigating Patient Preference for Self-guided or Guided Treatment

Alcohol Use Disorder

Canada
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

Effect of Varenicline on Reactivity to Smoking and Drinking Cues

Alcohol Dependence | Tobacco Dependence

Canada
Oregon Health and Science University
National Institute on Drug Abuse (NIDA)

Completed

Comparing Treatments for HIV-Infected Opioid and Alcohol Users in an Integrated Care Effectiveness Study (CHOICES)

Opioid Use Disorder | Alcohol Use Disorder

Canada, United States
McMaster University
Ontario Ministry of Health and Long Term Care

Withdrawn

Effects of an Evidence Service on Health System Policymakers' Use of Research Evidence

Use of Research Evidence

Canada
Women's College Hospital
Canadian Institutes of Health Research (CIHR)

Completed

The Effect of Mobile App Home Monitoring on the Number of In-Person Visits Following Ambulatory Surgery

Use of Mobile App Home Monitoring After Ambulatory Surgery

Canada
Ontario HIV Treatment Network
McMaster University

Unknown

Effects of an Evidence Service on Community-based AIDS Service Organizations' Use of Research Evidence

Use of Research Evidence

Canada
Centre for Addiction and Mental Health

Completed

Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence

Smoking Cessation | Tobacco Smoking | Tobacco Use Disorder | Substance Use Disorders | Molecular Mechanisms of Pharmacological Action | Tobacco Dependence | Physiological Effects of Drugs

Canada
Jon Bailey

Active, not recruiting

Continuous Serratus Anterior Blockade for Sternotomy (Cardiac-SAP)

Quality of Life | Postoperative Pain | Opioid Use

Canada
University of British Columbia
Provincial Health Services Authority

Withdrawn

Tobacco Retraining of Automatic Approach to Treat Individuals With Tobacco Dependence and Severe Concurrent Disorders.

Tobacco Retraining of Automatic Approach | Placebo Task

Canada
Karolinska Institutet
University of Copenhagen; Norwegian University of Science and Technology; University... and other collaborators

Completed

Nordic Gastric and Esophageal Tumor Study (NordGETS)

Cancer of the Esophagus | Drug Use | Cancer of Stomach

Sweden
Cukurova University

Completed

ESP Block in Pediatric Patients for Postoperative Analgesia (ESP1)

Quality of Life | Pain, Postoperative | Opioid Use

Turkey
Novartis Vaccines
Novartis

Completed

Study of the Safety and Immune Response of a Meningococcal Vaccine Administered to Healthy Infants

Prevention of Meningococcal Disease

Canada, United Kingdom
Celgene

Completed

Evaluate Risk/Benefit of Nab Paclitaxel in Combination With Gemcitabine and Carboplatin Compared to Gemcitabine and Carboplatin in Triple Negative Metastatic Breast Cancer (or Metastatic Triple Negative Breast Cancer) (tnAcity)

Breast Cancer | Metastatic Breast Cancer | Stage IV Breast Cancer | Triple-negative Breast Cancer | Recurrent Breast Cancer | Breast Tumor | Cancer of the Breast | Triple-negative Metastatic Breast Cancer | Estrogen Receptor- Negative Breast Cancer | HER2- Negative Breast Cancer | Progesterone Receptor- Negative...

United States, United Kingdom, Italy, Germany, Spain, Canada, Portugal, Australia, Austria, Greece, Brazil, France
University Health Network, Toronto
Merck Sharp & Dohme LLC

Active, not recruiting

Study of the Effects of Pembrolizumab in Patients With Advanced Solid Tumors (INSPIRE)

Advanced Solid Tumors | Triple Negative Breast Cancer | Epithelial Ovarian Cancer | Malignant Melanoma | Squamous Cell Cancer of Head and Neck

Canada
Foothills Medical Centre
Lantheus Medical Imaging

Completed

Can Ultrasound Replace Computed Tomography (CT) Scan in Those Unable to Have Computed Tomography (CT) Contrast Agents (CEUS_CT)

Nephrotoxicity of CT Contrast Agents | CT Scans in Those With Renal Compromise | Sensitivity to CT Contrast Agents | US With CEUS as Replacement for Unenhanced CT Scan

Canada
University of Calgary
The Sandra Schmirler Foundation: Advancing Neonatal Critical Care Fellowship...

Completed

Trends In Oxygen Saturation In Healthy Term Infants In The First Few Days Of Life: The "TOST" Study

Discharge Planning | Normative Oxygen Saturation Data Will Help us in | Describing Guidelines for Pulse Oximetry Screening | Identification of High Risk Infants

Canada
Boston Scientific Corporation

Completed

SuperNOVA Clinical Stenting Trial

Atherosclerosis of Native Arteries of the Extremities, Unspecified

Belgium, United States, United Kingdom, Japan, Austria, Canada, Germany
Boston Scientific Corporation

Completed

ELUVIA™ Drug-eluting Stent Versus Zilver® PTX® Stent (IMPERIAL)

Atherosclerosis of Native Arteries of the Extremities

New Zealand, United States, Belgium, Canada, Japan, Germany, Austria
Fusion Pharmaceuticals Inc.

Recruiting

A Phase 1/2 Study of [225Ac]-FPI-1434 Injection

Cervical Cancer | Breast Cancer | Ovarian Cancer | Endometrial Cancer | Uveal Melanoma | Adrenocortical Carcinoma | Advanced Solid Tumours | HER2-negative Breast Cancer | Triple Negative Breast Cancer (TNBC) | Head and Neck Squamous Cell Carcinoma (HNSCC)

United States, Australia, Canada
Oncorus, Inc.
Merck Sharp & Dohme LLC

Terminated

Study of ONCR-177 Alone and in Combination With PD-1 Blockade in Adult Subjects With Advanced and/or Refractory Cutaneous, Subcutaneous or Metastatic Nodal Solid Tumors or With Liver Metastases of Solid Tumors

Melanoma | Cancer | Breast Cancer | Solid Tumor | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Cancer | Advanced Solid Tumor | Liver Metastases | Colorectal Carcinoma | Non-melanoma Skin Cancer

United States, Canada
Ocellaris Pharma, Inc.

Recruiting

A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers

Sarcoma | Neoplasms | Renal Cell Carcinoma | Cervical Cancer | Cancer | Hepatocellular Carcinoma | Gastric Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Squamous Cell Carcinoma of Head and Neck | Bladder Cancer | Triple Negative Breast Cancer | Urothelial Carcinoma | Merkel Cell Carcinoma | Squamous... and other conditions

Canada
National Cancer Institute (NCI)

Completed

Belinostat and Azacitidine in Treating Patients With Advanced Hematologic Cancers or Other Diseases

Primary Myelofibrosis | Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Recurrent Disease | Recurrent Adult Acute Lymphoblastic Leukemia | Secondary Myelodysplastic Syndrome | de Novo Myelodysplastic... and other conditions

United States, Canada, New Zealand
Epizyme, Inc.

Completed

A Phase 1 Study of the EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma

Synovial Sarcoma | INI1-negative Tumors | Malignant Rhabdoid Tumor of Ovary | Rhabdoid Tumors

United States, France, Canada, Italy, Germany, United Kingdom, Australia, Denmark, Netherlands
Tesaro, Inc.
European Organisation for Research and Treatment of Cancer - EORTC; Breast... and other collaborators

Terminated

A Phase III Trial of Niraparib Versus Physician's Choice in HER2 Negative, Germline BRCA Mutation-positive Breast Cancer Patients (BRAVO)

Ovarian Neoplasms | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Neoplasms, Breast | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Carcinoma of Breast

United States, Spain, Belgium, Israel, United Kingdom, Italy, Poland, Canada, Hungary, Netherlands, France, Portugal, Greece, Iceland
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IVA Lip and Oral... and other conditions

United States, Canada
AstraZeneca

Active, not recruiting

First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours

Melanoma | Cervical Cancer | Small Cell Lung Cancer | Triple Negative Breast Neoplasms | Advanced Solid Tumours | Non-Small-Cell Lung Cancer | Gastroesophageal Cancer | Clear Cell Renal Cell Cancer | Squamous Cell Cancer of Head and Neck

United States, Spain, Canada, France
Galectin Therapeutics Inc.

Active, not recruiting

Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis (NAVIGATE)

Cirrhosis | NASH - Nonalcoholic Steatohepatitis | Prevention of Esophageal Varices

United States, France, Spain, Australia, Canada, Israel, Puerto Rico, Belgium, Argentina, Chile, Germany, Korea, Republic of, Mexico, Poland, United Kingdom
Epizyme, Inc.

Completed

A Study of Tazemetostat in Adult Participants With Soft Tissue Sarcoma

Synovial Sarcoma | Epithelioid Sarcoma | Renal Medullary Carcinoma | Malignant Rhabdoid Tumors (MRT) | Rhabdoid Tumors of the Kidney (RTK) | Atypical Teratoid Rhabdoid Tumors (ATRT) | Selected Tumors With Rhabdoid Features | INI1-negative Tumors | Malignant Rhabdoid Tumor of Ovary | Poorly Differentiated... and other conditions

France, United States, Australia, Taiwan, Belgium, United Kingdom, Canada, Germany, Italy

Clinical Trials on Negative Consequences of Alcohol Use in Canada

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