- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01257724
Effects of an Evidence Service on Community-based AIDS Service Organizations' Use of Research Evidence
Effects of an Evidence Service on Community-based AIDS Service Organizations' Use of Research Evidence: A Protocol for a Randomized Controlled Trial
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Background To support the use of research evidence by community-based organizations the investigators have developed 'Synthesized HIV/AIDS Research Evidence' (SHARE), which is an evidence service for those working in the HIV sector. SHARE consists of several components: 1) an online searchable database of HIV-relevant systematic reviews (retrievable based on a taxonomy of topics related to HIV/AIDS and open text search), 2) periodic email updates, 3) access to user-friendly summaries, and 4) peer relevance assessments. The objective is to evaluate whether this "full serve" evidence service increases the use of research evidence by community-based organizations as compared to a "self-serve" evidence service.
Methods/design The investigators will conduct a two-arm randomized controlled trial (RCT), along with a follow-up qualitative process study to explore the findings in greater depth. All community-based organizations affiliated with Canadian AIDS Society (n=120) will be invited to participate and will be randomized to receive either the "full-serve" version of SHARE or the "self-serve" version (a listing of relevant systematic reviews with links to records on PubMed and worksheets that help community-based organizations find and use research evidence) using a simple randomized design. All management and staff from each organization will be provided access to the version of SHARE that their organization is allocated to. The trial duration will be 10 months (two-month baseline period, six-month intervention period, and two month cross-over period), the primary outcome measure will be the mean number of logins/month/organization (averaged across the number of users from each organization) between baseline and the end of the intervention period and the secondary outcome will be intention to use research evidence as measured by a survey administered to one key decision-maker from each organization. For the qualitative study, one key organizational decision-maker from 15 organizations in each trial arm (n=30) will be purposively sampled. One-on-one semi-structured interviews will be conducted by telephone on their views about and their experiences with the evidence service they received, how helpful it was in their work, why it was helpful (or not helpful), what aspects were most and least helpful and why, and recommendations for next steps.
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Contacts and Locations
Study Locations
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Ontario
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Toronto, Ontario, Canada, M4T 1X3
- Ontario HIV Treatment Network
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- We will include all community-based organizations affiliated with the Canadian AIDS Society and from relevant provincial HIV/AIDS networks in Canada.
Exclusion Criteria:
- We will exclude organizations that do not have at least one key decision-maker who is comfortable participating and corresponding in English.
Study Plan
How is the study designed?
Design Details
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Full-serve evidence service
The full-serve evidence service consists of:
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SHARE (Synthesized HIV/AIDS Research Evidence) consists of several components:
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Active Comparator: Self-serve evidence service
Organizations allocated to the control group will only be provided website access to a listing of systematic reviews that are organized by year of publication with links to the record on PubMed (or another publicly available source when not available on PubMed) and access to worksheets that help community-based organizations find and use research evidence.
|
SHARE (Synthesized HIV/AIDS Research Evidence) consists of several components:
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
number of logins/month/organization
Time Frame: 6 months
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The investigators will track utilization of the evidence service at the organizational level by calculating the mean number of logins/month/organization (the total organizational logins/month will be averaged across the number of users from each organization).
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6 months
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Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Intention to use research evidence
Time Frame: Baseline and follow-up (after delivery of 6-month intervnetion)
|
The investigators will use the theory of planned behaviour to measure participants' intention to use research.
Using a manual designed to construct measures based on the theory, colleagues have developed and sought preliminary feedback on a data-collection instrument by first assessing face validity through interviews with key informants and then pilot testing it with 28 policymakers and researchers who completed it after participating in a knowledge translation intervention.
In addition, colleagues found the data-collection instrument to have moderate test-retest reliability.
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Baseline and follow-up (after delivery of 6-month intervnetion)
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Collaborators and Investigators
Sponsor
Collaborators
Investigators
- Principal Investigator: Michael G Wilson, PhD, McMaster University; Ontario HIV Treatment Network
- Principal Investigator: John N Lavis, MD, PhD, McMaster University
Publications and helpful links
Study record dates
Study Major Dates
Study Start
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Other Study ID Numbers
- HHS/FHS REB 10-268
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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