Clinical Trials on Nerve Sheath Tumors

Total 25680 results

Oslo University Hospital
Merck Sharp & Dohme LLC

Terminated

A Study of Pembrolizumab in Patients With Malignant Peripheral Nerve Sheath Tumor (MPNST), Not Eligible for Curative Surgery

Malignant Peripheral Nerve Sheath Tumour (MPNST)

Norway
Memorial Sloan Kettering Cancer Center
Astex Pharmaceuticals, Inc.

Recruiting

A Study of ASTX727 in People With Malignant Peripheral Nerve Sheath Tumors (MPNST)

Malignant Peripheral Nerve Sheath Tumors (MPNST)

United States
University of Florida
Epizyme, Inc.

Recruiting

Tazemetostat in Malignant Peripheral Nerve Sheath Tumors

Peripheral Nerve Sheath Tumor

United States
Adaptimmune

Recruiting

SPEARHEAD-3 Pediatric Study

Osteosarcoma | Neuroblastoma | Synovial Sarcoma | Malignant Peripheral Nerve Sheath Tumor (MPNST)

United States
M.D. Anderson Cancer Center

Recruiting

Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Recurrent Rhabdomyosarcoma | Refractory Neuroblastoma | Refractory Rhabdomyosarcoma | Desmoplastic Small Round Cell Tumor | Recurrent Malignant Peripheral Nerve Sheath Tumor | Ewing Sarcoma/Peripheral... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Vaccine Therapy in Treating Patients With Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery

Neurofibromatosis Type 1 | Metastatic Malignant Peripheral Nerve Sheath Tumor | Recurrent Malignant Peripheral Nerve Sheath Tumor

United States
Memorial Sloan Kettering Cancer Center
Bayer

Completed

Sorafenib and Dacarbazine in Soft Tissue Sarcoma

Sarcoma | Leiomyosarcoma | Malignant Peripheral Nerve Sheath Tumor | Synovial Sarcoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Whether Cancers With Specific Mutations Respond Better to Glutaminase Inhibitor, Telaglenastat Hydrochloride, Anti-Cancer Treatment, BeGIN Study

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | NF1 Mutation Positive Malignant Peripheral Nerve Sheath Tumor

United States
Fondazione I.R.C.C.S. Istituto Neurologico Carlo...

Active, not recruiting

Multisession Radiosurgery for Optic Nerve Sheath Meningiomas (ONSMsmSRS)

Optic Nerve Sheath Tumors, Benign

Italy
Semmelweis University
Charles University, Czech Republic; Jagiellonian University; St John of God Hospital...

Not yet recruiting

Learning Curve for the Visualization of Sacral Plexus on TVS (PlexUS)

Endometriosis | Radiculopathy | Nerve Sheath Tumor

Hungary
Memorial Sloan Kettering Cancer Center
Washington University School of Medicine; University of California, Los Angeles and other collaborators

Terminated

Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS)

Sarcoma | Leiomyosarcoma | Malignant Peripheral Nerve Sheath Tumor | Malignant Fibrous | Histiocytoma/Undifferentiated Pleomorphic Sarcoma

United States
Sarcoma Alliance for Research through Collaboration
United States Department of Defense; Synta Pharmaceuticals Corp.

Completed

SARC023: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors)

Sarcoma | Malignant Peripheral Nerve Sheath Tumors (MPNST)

United States
National Cancer Institute (NCI)

Recruiting

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

Colorectal Neoplasms | Advanced Breast Cancer | Advanced Solid Tumors | Malignant Peripheral Nerve Sheath Tumor | Metastatic Pancreatic Cancer | Pediatric Solid Tumor

United States
University of Texas Southwestern Medical Center

Withdrawn

Study of CPI-0610 in Patients With Malignant Peripheral Nerve Sheath Tumors

Peripheral Nerve Tumors

United States
Sarcoma Alliance for Research through Collaboration
Bristol-Myers Squibb

Completed

Trial of Dasatinib in Advanced Sarcomas

Chondrosarcoma | Chordoma | Hemangiopericytoma | Rhabdomyosarcoma | Sarcoma, Alveolar Soft Part | Epithelioid Sarcoma | Gastrointestinal Stromal Tumor (GIST) | Giant Cell Tumor of Bone | Sarcoma, Ewing's | Malignant Peripheral Nerve Sheath Tumors

United States
Johns Hopkins University

Recruiting

Multi-parametric Biomarker Development to Predict Malignant Conversion in Patients With Neurofibromatosis Type 1

Neurofibromatosis 1 | Atypical Neurofibroma | Malignant Peripheral Nerve Sheath Tumor (MPNST) of Soft Tissue (Diagnosis)

United States
National Cheng-Kung University Hospital

Recruiting

Radiographic Prediction of the Nerve Origin of Neck Peripheral Nerve Sheath Tumors

Peripheral Nerve Sheath Tumors | Schwannoma of Neck

Taiwan
Washington University School of Medicine
Boston's Children Hospital

Recruiting

Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

Malignant Peripheral Nerve Sheath Tumors

United States, Canada, United Kingdom, India
Gulam Manji
Daiichi Sankyo

Active, not recruiting

PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors (PLX3397)

Sarcoma | Malignant Peripheral Nerve Sheath Tumors

United States
Novartis Pharmaceuticals

Terminated

Imatinib Mesylate Treatment of Patients With Malignant Peripheral Nerve Sheath Tumors

Malignant Peripheral Nerve Sheath Tumors

Germany
National Cancer Institute (NCI)

Active, not recruiting

Natural History Study of Patients With Neurofibromatosis Type I

Neurofibroma | Neurofibromatosis Type 1 | Malignant Peripheral Nerve Sheath Tumor | Optic Glioma | Plexiform Neurofibroma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Targeted Imaging of Glutamate Carboxypeptidase II With DCFPyL-PET

Malignant Tumors | Schwannomas

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb

Recruiting

Neoadjuvant Nivolumab Plus Ipilimumab for Newly Diagnosed Malignant Peripheral Nerve Sheath Tumor

Nerve Sheath Tumors

United States
Timothy Cripe

Completed

HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors

Soft Tissue Sarcoma | Osteosarcoma | Ewing Sarcoma | Neuroblastoma | Rhabdomyosarcoma | Wilms Tumor | Malignant Peripheral Nerve Sheath Tumor | Clival Chordoma | Non-CNS Solid Tumors

United States
University Hospital, Strasbourg, France

Unknown

Evolution of Cochleovestibular Schwannomas

Schwannoma

France
Washington University School of Medicine

Completed

Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma

Soft Tissue Sarcoma | Sarcoma, Soft Tissue | Leiomyosarcoma | Fibrosarcoma | Liposarcoma | Angiosarcoma | Malignant Peripheral Nerve Sheath Tumor | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Epithelioid Sarcoma | Myxofibrosarcoma

United States
Seoul National University Hospital

Completed

Assessment of Volumetric Growth Rates of Spinal Intradural Extramedullary Schwannoma

Schwannoma | Neurinoma

Korea, Republic of
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0330 Erlotinib in Treating Patients With Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumor

Sarcoma

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Terminated

A Clinical Trial to Evaluate the Safety and Efficacy of AL2846 Capsules in Chinese Patients With Type I Neurofibromatosis

Neurofibromatosis and Malignant Peripheral Nerve Sheath Tumors

China
Assiut University

Unknown

Endoscopic-assisted Microsurgical Removal of Cerebellopontine Angle Lesions

Cerebellopontine Angle Tumor
Sarcoma Alliance for Research through Collaboration
United States Department of Defense; Genentech, Inc.; Novartis Pharmaceuticals

Completed

SARC016: Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath Tumors

Sarcoma | Malignant Peripheral Nerve Sheath Tumors | MPNST

United States
University Health Network, Toronto

Active, not recruiting

A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients

Soft Tissue Sarcoma | Leiomyosarcoma | Endometrial Stromal Sarcoma | Malignant Peripheral Nerve Sheath Tumor (MPNST)

Canada
National Cancer Institute (NCI)

Completed

Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma

Rhabdomyosarcoma | Recurrent Osteosarcoma | Recurrent Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Childhood Angiosarcoma | Childhood Epithelioid Sarcoma | Childhood... and other conditions

United States, Canada
Ascentage Pharma Group Inc.
Merck Sharp & Dohme LLC

Recruiting

A Study of APG-115 in Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

Melanoma | P53 Mutation | Uveal Melanoma | Cutaneous Melanoma | Mucosal Melanoma | Malignant Peripheral Nerve Sheath Tumors | MPNST | Unresectable or Metastatic Melanoma or Advanced Solid Tumors | MDM2 Gene Mutation

United States, Australia
University Hospital, Strasbourg, France

Unknown

MRI Scan and Intra-labyrinthine Schwannoma

Schwannoma

France
Muhammad Magdy Gaber
Cairo University

Completed

Compare the Operating Condition of Two Levels of Muscle Relaxation on Facial Nerve MEP Monitoring in CPA Surgery

Cerebellopontine Angle Tumor

Egypt
Imperial College London

Recruiting

Use of Non-invasive Optical Analysis in Neurosurgery

Glioma | Meningioma | Brain Metastases | Schwannoma | Brain Tumour

United Kingdom
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors

Solid Tumor | Rhabdoid Tumor | Wilms Tumor | Nephroblastoma | Malignant Peripheral Nerve Sheath Tumors | MPNST | XPO1 Gene Mutation

United States
Jona Hattangadi-Gluth

Recruiting

Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients

Glioma | Meningioma | Primary Brain Tumor | Schwannoma

United States
Advanced Accelerator Applications

Completed

A Study Comparing Treatment With 177Lu-DOTA0-Tyr3-Octreotate to Octreotide LAR in Patients With Inoperable, Progressive, Somatostatin Receptor Positive Midgut Carcinoid Tumours (NETTER-1)

Carcinoid Tumor of the Small Bowel | Neuroendocrine Tumour

United States, United Kingdom, Italy, Belgium, France, Germany, Portugal, Spain
Hospices Civils de Lyon

Unknown

The Lyon Real World Evidence in Metastatic NeuroEndocrine Tumours (LyREMeNet)

Metastatic Cancer | Gastro-enteropancreatic Neuroendocrine Tumor | Health Care Costs

France
Aveni Foundation

Available

Expanded Access for DeltaRex-G for Osteosarcoma, Chondrosarcoma, Soft Tissue Sarcoma, Pancreas and Breast Cancer

Sarcoma | Soft Tissue Sarcoma | Pancreatic Cancer | Osteosarcoma | Chondrosarcoma | Chordoma | Carcinoma of Breast | MPNST (Malignant Peripheral Nerve Sheath Tumor)

United States
Ain Shams University

Recruiting

Women's Access to Mobile Phones and Willingness to Utilize mHealth Interventions for Oral Health Promotion in Egypt

mHealth | eHealth | Oral Health

Egypt
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma

Recurrent Neuroblastoma | Recurrent Rhabdomyosarcoma | Wilms Tumor | Recurrent Malignant Peripheral Nerve Sheath Tumor | Recurrent Synovial Sarcoma | Pleuropulmonary Blastoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Leiomyosarcoma | Fibrosarcoma | Liposarcoma | Mesenchymal Chondrosarcoma | Stage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Malignant Peripheral Nerve Sheath Tumor | PEComa | Synovial Sarcoma | Epithelioid Sarcoma | Alveolar Soft Part Sarcoma | Undifferentiated High Grade Pleomorphic... and other conditions

United States, Canada, Puerto Rico
Beijing Tiantan Hospital

Recruiting

Trigeminal Nerve Cardiac Reflex During Resection of Cerebellopontine Angle Tumors and Postoperative Myocardial Injury

Myocardial Injury | Trigeminal Cardiac Reflex

China
Taipei Veterans General Hospital, Taiwan

Unknown

Evaluation of Acupuncture Effects for Complications After Surgery of Cerebellopontine Angle Tumor in Skull Base

Quality of Life | Acupuncture | Neuromuscular Blockade | Complication of Treatment | Tumor, Brain | Skull Base Tumor | Cerebellopontine Angle Tumor

Taiwan
Seattle Children's Hospital

Active, not recruiting

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Melanoma | Soft Tissue Sarcoma | Carcinoma | Osteosarcoma | Ewing Sarcoma | Rhabdoid Tumor | Neuroblastoma | Retinoblastoma | Rhabdomyosarcoma | Wilms Tumor | Hepatoblastoma | Synovial Sarcoma | Desmoplastic Small Round Cell Tumor | Germ Cell Tumor | Pediatric Solid Tumor | Clear Cell Sarcoma | Malignant Peripheral Nerve Sheath...

United States
University Hospital, Strasbourg, France

Unknown

Scleral Hydrops and Intralabyrinthine Schwannoma

Hydrops Saccular

France
OHSU Knight Cancer Institute
Novartis Pharmaceuticals; Oregon Health and Science University

Completed

Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery

Stage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Locally Advanced Leiomyosarcoma | Unresectable Leiomyosarcoma | Myxofibrosarcoma | Metastatic Malignant Peripheral Nerve Sheath Tumor | Metastatic Synovial Sarcoma | Metastatic Undifferentiated Pleomorphic Sarcoma | Unresectable... and other conditions

United States

Clinical Trials on Nerve Sheath Tumors

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